Clinical trials: Stem Cell Transplant Complications
Stem Cell Transplant Complications, Hyperglycemia
Malglycemia in the Pediatric Hematopoietic Stem Cell Transplant Population
This is a retrospective chart review of patients who underwent a hematopoietic stem cell transplant (HSCT) between 1994 and 2016 to evaluate incidence of malglycemia and the relationship to specific outcomes.
- Conditions
- Stem Cell Transplant Complications, Hyperglycemia, Hypoglycemia
- Trial name
- NCT03482154
- Testing
- Hematopoietic Stem Cell Transplant
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Colorado, Denver
Graft vs Host Disease, Complications of Organ Transplant Stem Cells
CEC Count Changes to Support GvHD Diagnosis.
In consideration of the fact that the vascular endothelium has been shown to be a target of GvHD in early stage and that the count of CEC may represent a marker of endothelial damage, we want to evaluate the changes in CEC counts…
- Conditions
- Graft vs Host Disease, Complications of Organ Transplant Stem Cells, Endothelial Dysfunction
- Trial name
- ALLOCEC (NCT02064972)
- Testing
- Patients undergoing allo-HSCT, who manifest GvHD.
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Stem Cell Transplant Complications, Relapse Leukemia
Decitabine Plus mBU/CY Preconditioning for Relapse/Refractory Acute Leukemia
Allogeneic haematopoietic stem cell transplantation (allo-HSCT) remains one of the currently available curative therapies for acute leukemia (AL). Leukemia relapse is one of the mainly causes of transplant failure.
- Conditions
- Stem Cell Transplant Complications, Relapse Leukemia, Refractory Leukemia
- Trial name
- NCT03799224
- Testing
- Decitabine, mBU/CY and ATG, mBU/CY
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Peking University People's Hospital
Oral Disease, Graft-versus-host-disease
Prevalence of Chronic Oral Graft Versus Host Disease Risk Factors in Pediatric Patients
our aim is estimating the Prevalence and predicting risk factors for developing chronic oral graft versus host disease in pediatric patients subjected to hematopoietic stem cells transplantation
- Conditions
- Oral Disease, Graft-versus-host-disease, Stem Cell Transplant Complications, Pediatric Disorder
- Trial name
- NCT03880214
- Volunteers
- 250 people
- Sponsor
- yasmeen magdi sholkamy
Stem Cell Transplant Complications, Delirium
Feasibility of Prophylactic Haldol to Prevent Delirium in Cancer Patients
This research study proposes to conduct an open label, feasibility study administering prophylactic oral haldol to patients undergoing a hematopoietic stem cell transplant (HSCT).
- Trial name
- PHDC (NCT03489551)
- Testing
- Haldol
- Volunteers
- 17 people
- Sponsor
- Michelle Weckmann
Stem Cell Transplant Complications, Graft Versus Host Disease, Acute
Fecal Microbiota Transplantation for Steroid Resistant and Steroid Dependent Gut Acute Graft Versus Host Disease
The investigators hypothesize that perturbations in the intestinal microbiota following allogeneic hematopoietic stem cell transplantation (HSCT) are essential for the development and propagation of acute graft-versus-host…
- Conditions
- Stem Cell Transplant Complications, Graft Versus Host Disease, Acute, Fecal Microbiota Transplantation
- Trial name
- NCT03214289
- Testing
- Fecal Microbiota Transplantation
- Where
- Israel
- Volunteers
- 4 people
- Sponsor
- Sheba Medical Center
Lymphoma, Non-Hodgkin, Lymphoma, Hodgkin
Low Dose Plerixafor Plus G-CSF in Mobilizing Stem Cells for Autologous Peripheral Blood Transplantation
Plerixafor, is added to mobilizing chemotherapy and G-CSF to overcome poor stem cell mobilization. We want to demonstrate that half of the commonly prescribed dose can be safely administered once as a single dose in first attempt…
- Conditions
- Lymphoma, Non-Hodgkin, Lymphoma, Hodgkin, Myeloma, Stem Cell Transplant Complications
- Trial name
- NCT03244930
- Testing
- Plerixafor 0.12 mg/kg
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Acute Myeloid Leukemia, Graft-versus-host-disease
Changes in the Gut Microbiota of Patients Undergoing Allogeneic Stem Cell Transplantation (COLLECT)
COLLECT is a monocentric, prospective, observational study, which aims to assess the association between changes in the intestinal microbiota and the incidence of gastrointestinal graft-versus-host diseases (GvHD).
- Conditions
- Acute Myeloid Leukemia, Graft-versus-host-disease, Allogeneic Hematopoietic Stem Cell Transplantation, Stem Cell Transplant Complications
- Trial name
- COLLECT (NCT03148197)
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Cologne
Stem Cell Transplant Complications
Role of Stem Cell Therapy in Interstitial Pulmonary Fibrosis
Currently, the application status of MSCs as treatment modalities in IPF is still in its infancy and remains exploratory. Although a number of safety and efficacy clinical trials of MSCs as therapeutic options in immune-mediated…
- Trial name
- NCT03187431
- Testing
- autologous bone marrow mesenchymal stem cells
- Volunteers
- 12 people
- Sponsor
- Assiut University
Complications of Organ Transplant Stem Cells Umbilical Cord
Treatment Protocol of Child SAA With the Injection of Mesenchymal Stem Cells（Umbilical Cord Derived）
Mesenchymal Stem Cells (MSC) is a non Hematopoietic Stem Cells (HSC) in adult bone marrow and takes part in the bone marrow microenvironment.
- Trial name
- MSC-SAA (NCT02218437)
- Testing
- MSC+ATG
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences