Clinical trials: Stenosis, Spinal
Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb
Cost Effectiveness of OMT for Chronic Low Back Pain
The specific aim of this study is to conduct a prospective, multicenter cohort study over four months to compare the cost of standard of allopathic care (control group, N=90) versus standard of care plus osteopathic manipulative…
- Conditions
- Lumbar Radiculopathy, Lesion of Sciatic Nerve, Left Lower Limb, Lesion of Sciatic Nerve, Right Lower Limb, Lumbar Spinal Stenosis
- Trial name
- NCT03532230
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- Rowan University
Spinal Stenosis
The Impact of Spinal Manipulation on Leg Movement in Lumbar Spinal Stenosis Patients
The objectives of the proposed research are to quantify the impact on motor performance of a single SM intervention on surgical waitlist patients with degenerative Lumbar Spinal Stenosis (LSS) using a recently established lower…
- Trial name
- NCT02118103
- Testing
- Spinal Manipulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Herniated Disc, Low Back Pain
Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation
This study tests the effectiveness of different treatments for the three most commonly diagnosed lumbar (lower) spine conditions.
- Trial name
- SPORT (NCT00000410)
- Testing
- Diskectomy, Non-surgical treatments
- Where
- 13 sites in United States
- Volunteers
- 501 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Low Back Pain, Recurrent, Degenerative Disc Disease
GDS Muscle and Articulation Chain Treatment for Chronic LBP and Spinal Stenosis
Our purpose is to conduct a pilot study to evaluate GDS muscle and articulation chain treatment for inoperable spine patients with degenerative changes in the lumbar spine, compared to "standard treatment" (any other chosen…
- Trial name
- GDS (NCT04436003)
- Testing
- Muscle and articulation chains GDS method
- Where
- Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Hospital of Vestfold
Lumbar Spinal Stenosis, Erector Spinae Plane Block
Erector Spinae Plane Block After Lumbar Spinal Stenosis Surgery
Lumbar spinae stenosis surgery is a frequent intervention resulting in important postoperative pain. Management of this postoperative pain is thus important. Different pain management therapies exist.
- Trial name
- NCT04403360
- Testing
- ESPB, Local infiltration by the surgeon
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Clinique Saint Pierre Ottignies
Back Pain, Radiculopathy Lumbar
Threshold Response of Lumbar Selective Nerve Root Block in Predicting Good Outcome Following Lumbar Foraminotomy
SNRB, as measured by the change in pain and objective functional ability, can solicit crucial information regarding a patient's clinical picture and can predict a patient's outcome post-surgery.
- Conditions
- Back Pain, Radiculopathy Lumbar, Degenerative Lumbar Spinal Stenosis
- Trial name
- NCT03801356
- Testing
- Selective Nerve Root Block
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- The Cleveland Clinic
Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy
Opioid Free and Opioid Based Anesthesia in Elective Lumbar Spine Surgery
This prospective, observational, non-randomized clinical study aims to evaluate the intraoperative and postoperative effects of opioid-free multimodal anesthesia compared with opioid-containing anesthesia methods in adult…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation With Radiculopathy, Lumbar Degenerative Spondylolisthesis, Lumbar Disc Degeneration
- Trial name
- NCT07489001
- Testing
- Opioid-free Anesthesia, Erector Spinae Plane Block, Opioid based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Marmara University
Scoliosis; Adolescence, Degenerative Disc Disease
Personalized Spine Study Group (PSSG) Registry
The primary objective of the study is a data collection initiative. The study will collect clinical and radiographic outcomes of patients implanted with patient specific rods.
- Conditions
- Scoliosis; Adolescence, Degenerative Disc Disease, Spinal Fusion, Kyphoscoliosis
- Trial name
- PSSG (NCT04601363)
- Testing
- Patient Specific Rod
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Colorado, Denver
Spinal Stenosis, Intermittent Claudication
Outcome of Surgery for Lumbar Spinal Stenosis - a Comparison of Data From Three National Quality Registries
There is no international consensus on evaluation and surgical treatment of Lumbar Spinal Stenosis (LSS). The indication for operative treatment is relative, and the variation in surgical rates and procedures is significant, both…
- Trial name
- NCT02897947
- Testing
- Surgery for lumbar spinal stenosis in Norway, Surgery for lumbar spinal stenosis in Sweden, Surgery for lumbar spinal stenosis in Denmark
- Volunteers
- 7,500 people
- Sponsor
- St. Olavs Hospital
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Lumbar Disc Herniation, Spondylolisthesis
The Spine PROMCO Study
Our primary objective is to design a cohort to determine the treatment outcome of different surgical interventions of the degenerative lumbar spine highlighting the expediency and value of the current surgical treatment program.
- Conditions
- Lumbar Disc Herniation, Spondylolisthesis, Spinal Stenosis
- Trial name
- Spine PROMCO (NCT05963815)
- Testing
- Spine surgery
- Where
- Netherlands
- Volunteers
- 4,000 people
- Sponsor
- Park Medical centrum
Lumbar Spinal Stenosis, Radiation Exposure
Radiation Exposure Reduction Protocol for Minimally Invasive Lumbar Decompression (mild) Techniques
To evaluate the efficacy of radiation reduction techniques to minimize clinician and patient exposure during minimally invasive lumbar decompression (MILD) procedure.
- Trial name
- NCT06651138
- Testing
- Fluoroscopy
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Lumbar Spinal Stenosis (LSS), Degenerative Spondylolisthesis G1
Multicenter Clinical Randomized Controlled Trial of Unilateral Biportal Endoscopic Spinal Surgery for Degenerative Grade 1 Spondylolisthesis Complicated With Lumbar Spinal Stenosis
The research objective of this project is to clarify and compare the efficacy of the unilateral biportal endoscopy (UBE) technique and traditional open decompression, fusion and internal fixation surgery in the treatment of…
- Trial name
- NCT07303348
- Testing
- UBE, PLIF
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital
Lumbar Spinal Stenosis, Low Back Pain
Radiological Lumbar Spinal Stenosis Level and Patient Questionnaires
One of the important causes of low back pain is lumbar spinal stenosis. With the increasing prevalence of magnetic resonance imaging (MRI), lumbar spinal stenosis grading systems have been developed.
- Trial name
- NCT07058350
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Lumbar Spinal Stenosis, Spinal Stenosis
Necessity of Fusion Following Decompression Surgery in Patients With Single-level Lumbar Stenosis
Long-term clinical results of two methods of surgical treatment (spinal decompression with or without fusion) in patients with single-level lumbar stenosis will be compared.
- Conditions
- Lumbar Spinal Stenosis, Spinal Stenosis, Spinal Fusion
- Trial name
- NCT05273879
- Testing
- decompression, fusion
- Where
- 2 sites in Russia
- Volunteers
- 86 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Degenerative Lumbar Spine Diseases, Lumbar Degenerative Disc Disease
Kore Fiber PLF Study
This is a prospective, randomized controlled trial evaluating Kore Fiber® versus autograft in adults undergoing posterolateral lumbar fusion (PLF).
- Conditions
- Degenerative Lumbar Spine Diseases, Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT07868510
- Testing
- Kore Fiber, Autologous bone graft
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Kolosis Bio, LLC
Sciatica
Comparing the Efficacy of Steroid, Acupuncture and Platelet Rich Plasma Injection in Patients With Sciatica
Disc herniation, stenosis of the spine and spondylolisthesis are the common causes of radiculitis in medical practice today, and can cause symptoms of sciatica.
- Trial name
- NCT03801512
- Testing
- Steroid, Acupuncture, Platelet Rich Plasma
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Medical University Hospital
Neuropathic Pain, Spinal Stenosis
Gabapentin Versus Transdermal Fentanyl Matrix for Chronic Neuropathic Pain
Gabapentin is a first line medication and fentanyl is second line medication in neuropathic pain. But, there is no head to head study on the efficacy of those medication in neuropathic pain.
- Trial name
- NCT01127100
- Testing
- transdermal fentanyl matrix, gabapentin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Lumbar Spinal Stenosis
Postmarket Registry for Evaluation of the Superion® Spacer
To gather evidence documenting the performance and clinical outcomes associated with treatment of moderate degenerative lumbar spinal stenosis using the Superion® Indirect Decompression System (IDS).
- Trial name
- PRESS (NCT04087811)
- Testing
- Superion® Indirect Decompression System (IDS)
- Where
- 66 sites in United States
- Volunteers
- 1,674 people
- Sponsor
- Boston Scientific Corporation