Clinical trials: Stenosis, Spinal
Spinal Stenosis, Pain, Postoperative
Postoperative Analgesia With Buprenorphine for Postoperative Pain Control and Quality of Life After Spinal Surgery
Major purpose of this research is to evaluate the effect and usefulness of Buprenorphine transdermal system (MTDS) among the patients with lumbar spinal disease who was performed the single-level posterior lumbar fusion.
- Trial name
- NCT02416804
- Testing
- Buprenorphine, Tramadol
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Hospital
Low Back Pain
A Randomized, Equivalence Trial of Percutaneous Lumbar Adhesiolysis and Caudal Epidural Steroid Injections
The purpose of this study is to: evaluate the effectiveness of percutaneous epidural adhesiolysis in managing chronic low back and/or lower extremity pain in patients without post lumbar surgery syndrome or spinal stenosis and…
- Trial name
- NCT01053273
- Testing
- Caudal Epidural Injection, percutaneous adhesiolysis
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Degenerative Disc Disease, Herniated Disc
Bone Graft Materials Observational Registry
A multi-center, prospective, observational patient registry to collect information on the clinical outcomes and "real world" use of approved and commercially available bone graft substitutes, autograft and allograft.
- Conditions
- Degenerative Disc Disease, Herniated Disc, Spinal Stenosis, Spondylolithesis
- Trial name
- APPROACH-001 (NCT00974623)
- Testing
- Bone graft substitute, autograft or allograft
- Where
- 14 sites in United States, Hungary and 1 more
- Volunteers
- 329 people
- Sponsor
- Baxter Healthcare Corporation
Degenerative Disk Disease, Spinal Stenosis of Lumbar Region
Performance of Inductigraft in Spinal Fusion
This is an open-label non-randomised, prospective, post market study to evaluate the performance of Inductigraft (osteoinductive synthetic bone graft) in patients receiving posterolateral lumbar spine fusion through assessment of…
- Trial name
- APOLLO (NCT01452022)
- Testing
- Inductigraft
- Where
- 15 sites in Germany, Hungary and 3 more
- Volunteers
- 125 people
- Sponsor
- Baxter Healthcare Corporation
Hypertrophic Pyloric Stenosis, Spinal Anesthesia
Spinal Anesthesia and General Anesthesia for Pyloromyotomy - Surgical Outcomes a Comparison Retrospective Study
Background: The purpose of this retrospective study is to evaluate surgical outcomes of pyloromyotomy in infants performed under spinal anesthesia compares to general anesthesia.
- Conditions
- Hypertrophic Pyloric Stenosis, Spinal Anesthesia, General Anesthesia
- Trial name
- NCT03095144
- Testing
- Spinal anesthesia, General anesthesia
- Volunteers
- 100 people
- Sponsor
- Bnai Zion Medical Center
Lumbar Spinal Stenosis
Comparison of the Order of Treatment in Lumbar Spinal Stenosis
Patients with back pain with spinal stenosis of the lower back will be asked to volunteer for this research study. These patients don't need immediate surgery for this problem.
- Trial name
- NCT02103543
- Testing
- physical therapy, lumbar interlaminar epidural steroid injection, epidural steroid injection
- Where
- United States
- Sponsor
- Emory University
Lumbar Spinal Stenosis
Risk Factors for Ligamentum Flavum Hypertrophy in Lumbar Spinal Stenosis Patients
To measure ligamentum flavum thickness in patients with different nationalities, sexes, heights, ages, and weights from Xinjiang Uygur Autonomous Region of China with CT, explore the correlation between various factors and…
- Trial name
- NCT03057353
- Testing
- lumbar CT imaging
- Volunteers
- 104 people
- Sponsor
- Sixth Affiliated Hospital of Xinjiang Medical University
Spinal Stenosis
Neurogenic Intermittent Claudication Evaluation Study
The objective of the NICE study is to provide clinical evidence proving that the Aperius™ PercLID™ System is safe and non-inferior to standalone decompressive surgery with regards to clinical outcomes in patients suffering from…
- Trial name
- NICE (NCT00905359)
- Testing
- Aperius™ PercLID™ System, Standalone Decompressive Surgery
- Where
- 19 sites in Australia, Belgium and 8 more
- Volunteers
- 163 people
- Sponsor
- Medtronic Spinal and Biologics
Spinal Stenosis, Intervertebral Disc Displacement
Tranexamic Acid in Reducing Gross Hemorrhage and Transfusions of Spine Surgeries
Multilevel decompression and bone graft fusion is a most effective measure for treating degenerative lumbar spinal diseases. Yet, the surgery is commonly associated with large amount of perioperative blood loss and high demand…
- Trial name
- TARGETS (NCT03011866)
- Testing
- Wound topically irrigated with 500mg TXA, 1mg/kg/hr TXA intravenous infusion till the last suture
- Volunteers
- 176 people
- Sponsor
- Peking Union Medical College Hospital
Lumbar Spinal Stenosis Secondary to Other Disease
NanOss Bioactive With Autograft and Bone Marrow Aspirate in the Posterolateral Spine
The purpose of this study is to assess lumbar fusion using nanOss Bioactive bone void filler
- Trial name
- NCT02005341
- Testing
- nanOSS, Autograft
- Sponsor
- Pioneer Surgical Technology, Inc.
Degenerative Disc Disease, Spinal Stenosis
Effectiveness of Lumbar Fusion When NanOss Bioactive Is Used With Posterolateral Gutter Fusions
Spine fusion is one of the most common procedures performed in spinal surgery. Several surgical techniques can achieve a solid union, but the intertransverse posterolateral fusion (PLF) is the most widely used.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT01452516
- Testing
- nanOss Bioactive Bone void filler, Interbody FCage
- Where
- 7 sites in United States
- Volunteers
- 28 people
- Sponsor
- Pioneer Surgical Technology, Inc.
Degenerative Disc Disease, Spinal Stenosis
Comparison of nanOss Bioactive With Autograft and Bone Marrow Aspirate to Autograft in the Posterolateral Spine
nanOss Bioactive is approved for use in the U.S. The purpose of this study is to compare fusion results in the posterolateral spine using nanOss Bioactive mixed with autograft bone and bone marrow aspirate (BMA) on one side and…
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT01968993
- Testing
- nanOss Bioactive - posterolateral gutter
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Pioneer Surgical Technology, Inc.
Lumbar Spinal Stenosis
Study on the Treatment of Degenerative Lumbar Spine Stenosis With a Percutaneous Interspinous Implant
Neurogenic intermittent claudication is a specific symptom complex occurring in patients with lumbar spinal stenosis. Characteristic of this disease is the occurrence of increasing leg, buttock or groin pain with or without lower…
- Trial name
- NCT01057641
- Testing
- Spacer, physiotherapy
- Where
- 2 sites in Germany
- Volunteers
- 22 people
- Sponsor
- University of Cologne
Spinal Stenosis
Stabilimax Investigational Device Exemption (IDE) Clinical Investigation Patient Followup Study
The intent of this study is to complete the collection of clinical data on subjects enrolled in the Stabilimax Dynamic Spine Stabilization IDE clinical trial (#G060214) sponsored by the now defunct Applied Spine Technologies Inc…
- Trial name
- NCT01485289
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Rachiotek LLC
Spinal Stenosis
The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation in the Elderly With Spinal Stenosis Due to Degenerative Spondylolisthesis
The average life expectancy in Denmark is increasing resulting in an increasing part of the population having age-related disease, ex lumbar spinal stenosis (LSS).
- Trial name
- IVANOS (NCT01618435)
- Testing
- i-FACTOR
- Where
- 2 sites in Denmark
- Volunteers
- 108 people
- Sponsor
- Sygehus Lillebaelt
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Protection of Autonomic Nervous System During Lower Spine Surgical Procedures: A Safety and Feasibility Study
A safety and feasibility study of free-run and stimulated corporal electromyography (EMG) to assess autonomic neural function during spinal and/or pelvic surgery in women and men.
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Stenosis
- Trial name
- NCT02873182
- Testing
- Autonomic nervous system monitoring
- Volunteers
- 20 people
- Sponsor
- Stanley Skinner
Scoliosis, Kyphosis
Epsilon-Aminocaproaic Acid to Reduce the Need for Blood Transfusions During and Following Spine Surgery
Individuals who undergo spine surgery often have a significant loss of blood and may require multiple blood transfusions. Research has shown that epsilon-aminocaproic acid (EACA) may reduce the amount of blood lost during…
- Conditions
- Scoliosis, Kyphosis, Lordosis, Spondylitis
- Trial name
- NCT00320619
- Testing
- Epsilon-Aminocaproic Acid (EACA)
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Neuropathic Pain, Spinal Stenosis
Gabapentin Versus Transdermal Fentanyl Matrix for Chronic Neuropathic Pain
Gabapentin is a first line medication and fentanyl is second line medication in neuropathic pain. But, there is no head to head study on the efficacy of those medication in neuropathic pain.
- Trial name
- NCT01127100
- Testing
- transdermal fentanyl matrix, gabapentin
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Seoul National University Hospital
Lumbar Disc Herniation, Lumbar Spinal Stenosis
Long-term Outcomes of Surgical and Nonsurgical Management of Sciatica Secondary to a Lumbar Disc Herniation or Spinal Stenosis
The rate of success 12 months after surgery is reported to be 60-65% in patients with lumbar disc herniation and 60-70% in patients with spinal stenosis.
- Trial name
- NCT02836730
- Testing
- Low back pain surgery
- Where
- Denmark
- Volunteers
- 425 people
- Sponsor
- Back and Rehabilitation Center, Copenhagen