Clinical trials: Stenosis, Spinal
Spondylolisthesis, Spinal Stenosis
Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis
This study tests the effectiveness of different treatments for the three most commonly diagnosed conditions of the lower backbone (lumbar spine).
- Conditions
- Spondylolisthesis, Spinal Stenosis, Low Back Pain
- Trial name
- SPORT (NCT00000409)
- Testing
- Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented
- Where
- 13 sites in United States
- Volunteers
- 304 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Herniated Disc, Low Back Pain
Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation
This study tests the effectiveness of different treatments for the three most commonly diagnosed lumbar (lower) spine conditions.
- Trial name
- SPORT (NCT00000410)
- Testing
- Diskectomy, Non-surgical treatments
- Where
- 13 sites in United States
- Volunteers
- 501 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Spinal Stenosis, Low Back Pain
Spine Patient Outcomes Research Trial (SPORT): Spinal Stenosis
This study tests the effectiveness of different treatments for the three most commonly diagnosed conditions of the lower backbone (lumbar spine).
- Trial name
- NCT00000411
- Testing
- Decompressive laminectomy, Non-surgical treatments
- Where
- 13 sites in United States
- Volunteers
- 289 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Spinal Stenosis
Level of Activity in Lumbar Spinal Stenosis Patients Pre- and Post-surgery
The purpose of the proposed research is to explore the relationship between objectively measured physical activity and surgical intervention for lumbar spinal stenosis (LSS).
- Trial name
- NCT02154191
- Testing
- Surgical Intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Lumbar Spinal Stenosis
Magnetic Resonance Imaging (MRI) Interpretations for Lumbar Spinal Stenosis (LSS)
The objective of this study is to establish a relationship between the degree of radiologically established anatomical stenosis and the severity of self-assessed outcome measures in patients that have undergone and MRI.
- Trial name
- NCT01017692
- Testing
- MRI
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- State University of New York - Upstate Medical University
Multilevel Cervical Spinal Stenosis, Single Brachial Radiculopathy
Head-neck Coordination Analysis After Minimally Invasive Surgery in the Dorsal Cervical Spine
To proof patients' benefit of minimally invasive surgery in the dorsal cervical spine an apparatus to examine head-neck-coordination was constructed.
- Trial name
- MISDCS (NCT01988259)
- Testing
- Bilateral approach for Laminoplasty, Unilateral approach for laminoplasty, Subperiosteal approach for foraminotomy
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Schoen Klinik Hamburg Eilbek
Spinal Stenosis
The Impact of Spinal Manipulation on Leg Movement in Lumbar Spinal Stenosis Patients
The objectives of the proposed research are to quantify the impact on motor performance of a single SM intervention on surgical waitlist patients with degenerative Lumbar Spinal Stenosis (LSS) using a recently established lower…
- Trial name
- NCT02118103
- Testing
- Spinal Manipulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Spinal Stenosis, Spinal Cord Compression
Comparative Effectiveness of Microdecompression and Laminectomy for Central Lumbar Spinal Stenosis
Introduction: This observational study is designed to test the equivalence between the clinical effectiveness of microdecompression and laminectomy in the surgical treatment of central lumbar spinal stenosis.
- Trial name
- NCT02006901
- Testing
- microdecompression, laminectomy
- Where
- Norway
- Volunteers
- 721 people
- Sponsor
- St. Olavs Hospital
Spinal Stenosis, Back Pain
Postural Balance and Stability Among Patients With Cervical and Back Pain
High percentage of chronic back pain is due to spinal stenosis. The clinical picture is of 'neurogenic claudication' which effects postural balance and stability.
- Trial name
- NCT02395887
- Volunteers
- 80 people
- Sponsor
- Meir Medical Center
Spinal Stenosis
Acupuncture for Lumbar Spinal Stenosis
Acupuncture is widely used to manage chronic low back pain. Mounting evidence suggests the beneficial effects of acupuncture for mitigating chronic low back pain with acceptable minor adverse events.
- Trial name
- NCT01987622
- Testing
- Acupuncture, Usual care
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korean Medicine Hospital of Pusan National University
Spinal Stenosis
Effect of Nicardipine on Renal Function in Deliberate Hypotension
The aim of this study was to demonstrate the effect of nicardipine on renal function with creatinine clearance, serum cystatin C, urine output and fractional excretion of sodium during deliberate hypotension for spine surgery.
- Trial name
- NCT02271191
- Testing
- Nicardipine
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome
Efficacy of Pregabalin in Patients With Radicular Pain
The purpose of this study is to evaluate whether pregabalin is effective in reducing the pain in patients who present with radicular pain due to a herniated disc, spinal stenosis or failed back surgery syndrome.
- Conditions
- Neuropathy; Radicular, Lumbar, Lumbosacral, Failed Back Surgery Syndrome, Spinal Stenosis, Herniated Disc
- Trial name
- NCT00908375
- Testing
- Pregabalin, Sugar Pill
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Northwestern University
Lumbar Spinal Canal Stenosis
Irrigation Endoscopic Decompression
To evaluate a new endoscopic technique for lumbar spinal canal decompression.
- Trial name
- NCT02254590
- Testing
- Irrigation Endoscopic Decompressive Laminotomy
- Volunteers
- 104 people
- Sponsor
- Cairo University
Spinal Stenosis, Spondylolisthesis
Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures
The purpose of this retrospective data review is to evaluate the health economic drivers and complications of two surgical procedures: transsacral lumbar interbody fusion and transforaminal lumbar interbody fusion when used in…
- Conditions
- Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Trial name
- NCT02171169
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Baxano Surgical, Inc.
Spinal Stenosis, Spondylolisthesis
RAMP Study: A Study Comparing Two Lumbar Fusion Procedures
This is a post-marketing, on-label Efficacy, Effectiveness and Safety Study designed in a Multicenter, Randomized, Prospective format.
- Conditions
- Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Trial name
- RAMP (NCT01716182)
- Where
- 11 sites in United States
- Volunteers
- 200 people
- Sponsor
- Baxano Surgical, Inc.
Spinal Stenosis
Cognitive-Behavioral Physical Therapy
The overall objective of this application is to conduct a two-group randomized controlled trial (RCT) to gather preliminary evidence on the efficacy of a brief cognitive-behavioral based PT (CBPT) intervention in patients at-risk…
- Trial name
- CBPT (NCT01131611)
- Testing
- CBPT, Control-Attention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Vanderbilt University
Pseudoarthrosis, Spinal Stenosis
A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures
The purpose of this study is to demonstrate the relative efficacy of two lumbar fusion procedures: transacral lumbar interbody fusion when used in conjunction with unilateral or bilateral posterior pedicle screw fixation as an…
- Conditions
- Pseudoarthrosis, Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Trial name
- NCT01972256
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Baxano Surgical, Inc.
Lumbar Spinal Stenosis
Influence of Pain Sensitivity on Lumbar Surgery Outcomes
Pain sensitivity would be associated with surgical outcomes after lumbar spine surgery.
- Trial name
- NCT02134821
- Testing
- Surgery for lumbar spinal stenosis
- Where
- South Korea
- Volunteers
- 171 people
- Sponsor
- Seoul National University Hospital
Radiculopathy, Spondylolisthesis
Spondylolisthesis Treated With an iO-Flex® System Enabled Decompression
The purpose of this study is to evaluate the clinical performance of a decompression using the FDA cleared iO-Flex® System on-label in treating patients with spinal stenosis and stable grade I degenerative lumbar…
- Conditions
- Radiculopathy, Spondylolisthesis, Lumbar Spinal Stenosis
- Trial name
- STRiDE (NCT01338766)
- Testing
- Decompression using the iO-Flex® system
- Where
- 14 sites in United States
- Volunteers
- 100 people
- Sponsor
- Baxano Surgical, Inc.
Degenerative Disc Disease, Spinal Stenosis
Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable Screws
Trinica Anterior Lumbar Plate (ALP) System is a commercially available, supplemental fusion device for use in the lumbar or sacral spine (L1-S1) to treat instability.
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT00762723
- Testing
- Trinica Anterior Lumbar Plate System
- Where
- 3 sites in United States
- Volunteers
- 19 people
- Sponsor
- Zimmer Biomet