Clinical trials: Stent Occlusion
Coronary Artery Disease, Diabetes Mellitus
Outcome of Second Generation Drug-eLuting Stents in Patients With Diabetes Mellitus
Design: prospective, randomized, multi-center trial comparing the safety and efficacy in the prevention of target lesion failure (TLF) of second generation paclitaxel- versus ABT578- versus Everolimus- eluting stents Study…
- Trial name
- OCELOT (NCT01293773)
- Testing
- Taxus Element stent, Integrity Resolute stent, Xience Prime stent
- Where
- 2 sites in Italy
- Sponsor
- Policlinico Casilino ASL RMB
Coronary Artery Disease
The Bioresorbable Implants for Scaffolding Obstructions in Randomized Bifurcations (BIFSORB) Study
Coronary artery disease is often treated by implantation of permanent metallic stents.Coronary stents are required in the early healing phase after balloon dilatation but constitute a lifelong foreign body.
- Trial name
- BIFSORB (NCT02973529)
- Testing
- Absorb, Desolve
- Where
- 4 sites in Denmark, Latvia
- Volunteers
- 120 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease, Stent Restenosis
MACE in Different Drug-Eluting Stents
In this retrospective cohort study, all patients from Iranian registry were recruited and follow up after 5 years were recorded for MACE, and its relation to type and demographic data were evaluated
- Trial name
- NCT06470529
- Testing
- drug eluting stents
- Where
- Iran
- Volunteers
- 4,159 people
- Sponsor
- Shiraz University of Medical Sciences
Peripheral Arterial Disease
Paclitaxel Balloon Versus Standard Balloon in In-stent Restenoses of the Superficial Femoral Artery (PACUBA I Trial)
Prospective monocenter single-blind randomized (1:1) investigator sponsored clinical trial, in which consecutive patients candidates for percutaneous intervention of angioplasty to treat symptomatic in-stent restenosis of the SFA…
- Trial name
- PACUBA 1 (NCT01247402)
- Testing
- drug eluting balloon angioplasty, standard balloon angioplasty
- Where
- 2 sites in Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Peripheral Arterial Disease
Clinical Trial Investigating the BeGraft Peripheral Plus Stent Graft System for Iliac Lesion Treatment
The BeGraft Plus PMCF Trial investigates the efficacy of the BeGraft Peripheral Plus Stent Graft System in the treatment of iliac stenotic or occlusive lesions (TASC A, B, C and D).
- Trial name
- BeGraft+PMCF (NCT03286361)
- Testing
- BeGraft Peripheral Plus Stent Graft System
- Where
- 9 sites in Belgium, France
- Volunteers
- 70 people
- Sponsor
- ID3 Medical
Coronary Artery Disease, Image
Concurrent OCT and FFR-guided PCI in CAD
The present study is a prospective randomized clinical trial aimed to compare the therapeutic strategy of angiography-guided versus concurrent OCT/FFR-guided intervention in patients with coronary artery disease.
- Conditions
- Coronary Artery Disease, Image, Atheroscleroses, Coronary
- Trial name
- OPTICARE-CAD (NCT06182683)
- Testing
- optical coherence tomography and fractional flow reserve, Coronary angiography
- Where
- South Korea
- Volunteers
- 700 people
- Sponsor
- Korea University Guro Hospital
Coronary Artery Disease
Choice Of Optimal Strategy For Bifurcation Lesions With Normal Side Branch
Few data are available about the late patency of side branches in association with the currently used stent types and implantation techniques.
- Trial name
- CROSS (NCT00694005)
- Testing
- kissing balloon, without kissing balloon angioplasty "leave alone"
- Where
- 11 sites in South Korea
- Volunteers
- 504 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease
OPTIMIZE PCI: Multicenter Randomized Trial of OCT Compared to IVUS and Angiography to Guide Coronary Stent Implantation
The objective of this clinical investigation is to demonstrate the safety and efficacy of an OCT guided strategy for stent implantation
- Trial name
- ILUMIEN III (NCT02471586)
- Testing
- Coronary PCI guided by IVUS, Coronary PCI guided by OCT, Coronary PCI guided by Angiography
- Where
- 29 sites in United States, Belgium and 6 more
- Volunteers
- 450 people
- Sponsor
- Abbott Medical Devices
Drug-eluting Stent, Coronary Artery Disease
Efficacy of OSFIT Drug-Eluting Stent in Coronary Ostial Artery Stenosis
The purpose of this observational study is to evaluate the long-term effectiveness and safety of the OSFIT drug-eluting stent designed to facilitate procedures in coronary artery lesions.
- Trial name
- NCT06066450
- Testing
- Genoss® DES system, Genoss® Osfit system
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Genoss Co., Ltd.
Coronary Artery Disease, Angina Pectoris
Prevention of Instent Renarrowing With Aggressive Glucose Lowering With Pioglitazone in Diabetic Patients
Patients with diabetes have worse outcomes after percutaneous coronary intervention (PCI) procedures, compared to those patients without diabetes.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Type 2 Diabetes Mellitus, Percutaneous Coronary Intervention
- Trial name
- PPAR-G (NCT00819325)
- Testing
- pioglitazone, oral hypoglycemic agents
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Queen Elizabeth II Health Sciences Centre
Pulmonary Artery Stenosis
Post-Approval Study of PALMAZ MULLINS XD™ in Treating Pulmonary Artery Stenosis
The purpose of the clinical investigation is to characterize clinical outcomes and to assess the real-world use of the commercial PALMAZ MULLINS XD™ Pulmonary Stent.
- Trial name
- REALPASS (NCT07122518)
- Testing
- PALMAZ MULLINS XD™ Pulmonary Stent
- Where
- 8 sites in United States
- Volunteers
- 35 people
- Sponsor
- Cordis US Corp.
Aorto-iliac Occlusive Disease
Prospective, Non-Randomised Clinical Trial to Investigate the BeGraft Aortic Stent Graft System and the BeGraft Peripheral Stent Graft System Treating Aortic-iliac Occlusive Disease
This is a prospective, multi-center, investigational study to evaluate safety and performance of the BeGraft Aortic balloon expandable covered Stent Graft System and the BeGraft Peripheral balloon expandable covered stent Graft…
- Trial name
- NCT05805111
- Testing
- endovascular intervention
- Where
- 15 sites in Germany, Netherlands
- Volunteers
- 109 people
- Sponsor
- Marc Bosiers, MD
Coronary Artery Disease
Supralimus-Core™ Pharmacokinetic (PK) Study
The primary objective of this study is to evaluate the pharmacokinetic (PK) and safety associated with Supralimus-Core™ Sirolimus Eluting Coronary Stent system in the treatment of single de novo lesions in native coronary…
- Trial name
- NCT01121744
- Testing
- Supralimus-Core™ Sirolimus eluting Coronary Stent
- Where
- 4 sites in India
- Volunteers
- 20 people
- Sponsor
- Sahajanand Medical Technologies Limited
Atherosclerosis, Coronary Artery Disease
A Prospective, Multi-center Trial to Assess an Everolimus-Eluting Coronary Stent System (PROMUS Element™)
Compile acute (30-day) clinical outcomes data and 9-month angiographic and intravascular ultrasound (IVUS) data for the PROMUS Element™ Everolimus- Eluting Coronary Stent System in the treatment of patients with a single de novo…
- Trial name
- PLATINUM QCA (NCT00824434)
- Testing
- PROMUS Element™
- Where
- 17 sites in Australia, Malaysia and 2 more
- Volunteers
- 100 people
- Sponsor
- Boston Scientific Corporation
Carotid Stenosis
Remote Ischemic Conditioning Plus Stenting for Symptomatic Carotid Artery Stenosis
Remote ischemic conditioning (RIC) has emerged as a promising non-invasive strategy to protect the brain, with evidence suggesting its benefit in patients with carotid artery stenting (CAS).
- Trial name
- RICSICAS (NCT07412249)
- Testing
- Remote ischemic conditioning
- Where
- China
- Volunteers
- 300 people
- Sponsor
- General Hospital of Shenyang Military Region
Carotid Artery Diseases
A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach
The objective of this study is to evaluate acute device and technical success of the CGuard Prime™ Carotid Stent System (80cm) when used in conjunction with the Enroute NPS during Transcarotid Artery Revascularization procedures…
- Trial name
- NCT06653387
- Testing
- CGuard Prime 80cm stent system
- Where
- 8 sites in United States
- Volunteers
- 50 people
- Sponsor
- InspireMD
Coronary Artery Disease
Randomized Evaluation of Sirolimus-eluting Versus Everolimus-eluting Stent Trial
The purpose of this study is to evaluate whether the newly-approved everolimus-eluting stent is not inferior to the sirolimus-eluting stent in terms of the rate of target-lesion revascularization at 1-year and death or myocardial…
- Trial name
- RESET (NCT01035450)
- Testing
- Everolimus-eluting stent, Sirolimus-eluting stent
- Where
- Japan
- Volunteers
- 3,206 people
- Sponsor
- Takeshi Morimoto
Coronary Artery Disease, Drug Resistance
Efficacy of Adjusted Clopidogrel Dose in Patients With Insufficient Platelet Inhibition
This study is a prospective, single-center evaluation of the efficacy of clopidogrel dose adjustment in patients with insufficient platelet inhibition after elective coronary stent implantation.
- Trial name
- NCT00302913
- Testing
- Adjustment of clopidogrel dose
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University Heart Center Freiburg - Bad Krozingen
Coronary Artery Disease, Angina Pectoris
The Real-World Endeavor Resolute Versus XIENCE V Drug-Eluting Stent Study in Twente
The TWENTE Study is a single center prospective single-blinded randomized study. Randomization will involve the type of Drug-Eluting Stent (DES) used in study population.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Unstable Angina Pectoris, Coronary Stenosis
- Trial name
- TWENTE (NCT01066650)
- Testing
- Endeavor Resolute (Biolinx-based Zotarolimus-eluting stent), Xience V (Everolimus-eluting stent)
- Where
- Netherlands
- Volunteers
- 1,391 people
- Sponsor
- Foundation of Cardiovascular Research and Education Enschede
Atherosclerosis, Peripheral Artery Disease
The ABSORB BTK (Below The Knee) Clinical Investigation
The purpose of the ABSORB BTK Clinical Investigation is to evaluate the safety and efficacy of the Everolimus Eluting Bioresorbable Vascular Scaffold System (BVS) in subjects with critical limb ischemia (CLI) following…
- Conditions
- Atherosclerosis, Peripheral Artery Disease, Peripheral Vascular Disease, PAD
- Trial name
- NCT01341340
- Testing
- Everolimus Eluting BVS
- Where
- Belgium
- Volunteers
- 2 people
- Sponsor
- Abbott Medical Devices