Clinical trials: Step
Sedentary Behaviors, Physical Inactivity
Step-Up vs. Running Exercise at Matched Heart Rate Zones in Sedentary Males
This study compares the effects of two aerobic exercise methods - loaded step-up exercise and treadmill running - on cardiovascular fitness, leg strength, heart rate variability, and recovery in sedentary adult males.
- Trial name
- NCT07585617
- Testing
- Loaded Step-Up Exercise, Treadmill Running
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ankara University
Multiple Myeloma, Relapsed Cancer
Plan Development for Giving Teclistamab in the Outpatient Setting
This is a pilot study to develop an outpatient-based process for the administration of teclistamab for for relapsed/refractory multiple myeloma patients and to evaluate the burden on caregivers of patients receiving outpatient…
- Conditions
- Multiple Myeloma, Relapsed Cancer, Refractory Cancer
- Trial name
- NCT06251076
- Testing
- Teclistamab, Tocilizumab
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University Health Network, Toronto
Chronic Stroke Patients
Lateral Stair Walking Training After Chronic Stroke
The experimental group received 15 minutes of lateral stair walking exercise and 30 minutes of traditional physiotherapy (strengthening exercise, balance training and gait training) each time.
- Trial name
- NCT03702517
- Testing
- lateral stair walking exercise, traditional physiotherapy
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Anxiety, Depression
Child STEPS for Youth Mental Health in Maine Sustainability
The overarching goal of this project is to study the sustainability of MATCH-ADTC within community mental health clinics, to learn what is needed for evidence-based practices (EBPs) to take root and thrive within a public system.
- Conditions
- Anxiety, Depression, Trauma, Behavior Problems
- Trial name
- NCT03112304
- Testing
- MATCH-ADTC, TRAC
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Harvard University
Mask Usage Condition
Acute Mask Effects on Walk Distance and Vital Signs
The goal of this prospective observational study is to investigate the acute effects of mask use on walking distance and vital signs in healthy individuals aged 18-24 years.
- Trial name
- NCT06634238
- Testing
- Incremental shuttle walk test
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nagihan Acet
Trauma, Posttraumatic Stress Disorder
Increasing Treatment Access in Trauma Exposed Children: Developing an Adapted Step One Intervention (Pilot)
One of the most common and widely disseminated trauma treatments is Trauma Focused Cognitive Behavioral Therapy (TF-CBT). TF-CBT is a therapist-led, structured and sequential intervention, with treatment organized around…
- Trial name
- NCT07396935
- Testing
- Personalized Stepped Care Cognitive Behavioral Therapy for Children after Trauma (pSC-CBT-CT)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Pain, Low Back Pain
Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics
The main objective of the study is to evaluate the effectiveness, tolerability, and safety of tapentadol hydrochloride prolonged release in subjects suffering from severe chronic low back pain (LBP) who are taking either WHO Step…
- Trial name
- NCT00983385
- Testing
- Tapentadol PR, Observation period
- Where
- 46 sites in Austria, Croatia and 7 more
- Volunteers
- 208 people
- Sponsor
- Grünenthal GmbH
Acute Ischemic Stroke
Ali Pay Intelligent Navigation Applet-aided Pre-hospital Triage for Non-emergency Medical Service Patients With Acute Ischemic Stroke
According to the Bigdata Observatory platform for Stroke of China (BOSC), the proportion of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis or endovascular treatment in China is 5.64% and 1.45%…
- Trial name
- i-Path (NCT06613074)
- Testing
- Ali Pay intelligent navigation applet
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Dental Pulp Necrosis, Dental Pulp Disease
Digitized Assessment for the Survival of Mature Anterior Teeth With Periapical Lesion After One Step Regenerative Approach Using Different Asepsis Maneuvers
Trial is designed to allow revascularization and tissue engineering in necrotic teeth with peripical lesion in a single visit approach.
- Conditions
- Dental Pulp Necrosis, Dental Pulp Disease, Dental Pulp; Degeneration
- Trial name
- RCT (NCT03652129)
- Testing
- Disinfection
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Feeding and Eating Disorders of Childhood
Impact of the "Ten Steps for Healthy Feeding of Children Younger Than Two Years" in Health Centers
A cluster randomized field trial to evaluate the impact that training healthcare workers in healthy feeding practices has on the nutrition and health of children.
- Trial name
- NCT00635453
- Testing
- Dietary Advice
- Where
- Brazil
- Volunteers
- 715 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Renal Dialysis, Kidney Failure, Chronic
Quality of Life of Frail Aged Patients in Incremental Hemodialysis
End stage renal disease (ESRD) is a major public health problem. The dialysis population is aging. As a result we observe a high prevalence of frailty among dialysis patients (ranges from 3 to 10 fold higher than in the…
- Conditions
- Renal Dialysis, Kidney Failure, Chronic, Frailty
- Trial name
- Qualifragilys (NCT03782519)
- Testing
- Dialysis frequency reduction, Frailty diagnosis
- Where
- France
- Volunteers
- 783 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Caries Class II
Clinical Evaluation of Fiber Reinforced Resin Composite Base Versus Incremental Packing of Nanohybrid Resin Composite
A clinical trial, comparing two different incrementation techniques in the restoration of proximal caries in permanent posterior teeth .
- Trial name
- NCT04019145
- Testing
- EverX Posterior, Resins, Composite
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Kidney Diseases
System Interventions to Achieve Early and Equitable Transplants Study - Long-Term
STEPS-LT is an extension of the System Interventions to Achieve Early and Equitable Transplants (STEPS) study. STEPS-LT will follow participants that previously completed the STEPS study to evaluate sustained behavioral…
- Trial name
- STEPS-LT (NCT07515794)
- Where
- United States
- Volunteers
- 793 people
- Sponsor
- Wake Forest University Health Sciences
Peyronie Disease
Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease
Our team has previously demonstrated efficacy in performing a novel collagenase Clostridium histolyticum (CCH) injection protocol in men who previously failed to achieve a response to an initial 4 series of CCH.
- Trial name
- NCT06649539
- Testing
- Collagenase Clostridium Histolyticum, RestoreX, Sildenafil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Critical Illness
Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients
This pilot study will study the impact of critical illness and ICU processes of care on the trajectory and development of frailty.
- Trial name
- FORECAST (NCT04605029)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Dr. John Muscedere
Healthy
Daily Intake of Cocoa Flavanols and Arterial Stiffness in Humans
A randomized, double-masked and cross-over dietary intervention study to investigate the effects of diet supplementation with cocoa flavanols on arterial stiffness in healthy adult human subjects.
- Trial name
- NCT03587883
- Testing
- Cocoa flavanols I, Control I, Cocoa flavanols II
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Tuberculosis
A Step Forward for Unraveling the Immune Mechanisms and Tools for Tuberculosis Spectrum Management
Tuberculosis (TB) is a significant infectious disease worldwide, with millions of people infected and major impact on mortality and public health.
- Trial name
- TB-SPECTRUM (NCT07735754)
- Volunteers
- 940 people, healthy volunteers welcome
- Sponsor
- Irene Latorre Rueda
Sepsis
Single-dose/Multiple-doses Incremental Intravenous Injection of SY-005 （Recombinant Human Annexin A5）in Healthy Subjects
This is a single-dose/multiple-doses incremental, randomized, double-blind, parallel, placebo-controlled study on safety, tolerance and pharmacokinetics healthy subjects.
- Trial name
- NCT04217629
- Testing
- SY-005
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Suzhou Yabao Pharmaceutical R&D Co., Ltd.
Intervention Study, Physical Activity
Mi Band Step Challenge to Improve Body Composition in Overweight University Students
This is an eight-month research project using one group pretest-midst-posttest design. This study is based on self-efficacy and self-regulation of Social Cognitive Theory.
- Trial name
- NCT02893566
- Testing
- Mi Band Step Challenge
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Hemato-Oncologic Patients, Myelosuppression
Efficacy of Transfusions With Platelets Stored in Platelet Additive Solution II Versus Plasma
The purpose of this study is to evaluate the clinical efficacy of transfusions with platelets stored in platelet additive solution II compared to plasma storage.
- Conditions
- Hemato-Oncologic Patients, Myelosuppression, Thrombocytopenia
- Trial name
- NCT00151866
- Testing
- platelet transfusion
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- Sanquin Research & Blood Bank Divisions