Clinical trials: Stepped Care
Insomnia Disorder
Optimization of Insomnia Treatment in Primary Care
The primary objective of this pragmatic clinical trial is to evaluate the efficacy, feasibility, and adaptability of pharmacological and non-pharmacological treatments for insomnia disorder, delivered in primary care clinics.
- Trial name
- NCT03633305
- Testing
- Hypnotics, Online CBT, Face-to-face CBT
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- Laval University
Lung Cancer
Stepped Palliative Care Versus Early Integrated Palliative Care in Patients With Advanced Lung Cancer
This research study is evaluating ways to provide palliative care to patients who have recently been diagnosed with lung cancer
- Trial name
- STEP PC (NCT03337399)
- Testing
- Stepped PC, Early Integrated PC
- Where
- 3 sites in United States
- Volunteers
- 507 people
- Sponsor
- Massachusetts General Hospital
Geriatrics
Impact of a Transitional Care Program on 30-Day Hospital Readmissions for Elderly Patients Discharged From a Short Stay Geriatric Ward
In France, it has be estimated that the hospital readmission rate within 30 days of patients aged 75 or older is 14% (IC95% [12.0-16.7]), nearly a quarter being avoidable.
- Trial name
- PROUST (NCT02421133)
- Testing
- Transitional care program., standard care program
- Where
- 9 sites in France
- Volunteers
- 630 people
- Sponsor
- Hospices Civils de Lyon
Pancreatic Diseases, Pancreatic Neoplasms
POstopeRative Standardization of Care: THe Implementation of Best Practice After Pancreatic Resection
This Nationwide stepped-wedge cluster randomized trial is designed to evaluate if the implementation of a best practice algorithm for postoperative care results in a decrease in incidence of major complications and death after…
- Conditions
- Pancreatic Diseases, Pancreatic Neoplasms, Pancreatic Cancer, Pancreatitis
- Trial name
- PORSCH (NCT03400280)
- Testing
- Best practice algorithm for postoperative care
- Where
- 17 sites in Netherlands
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- St. Antonius Hospital
Cryptococcal Meningitis, Cryptococcus Neoformans
Operational Research for Cryptococcal Antigen Screening
This will be a stepped wedge randomized trial design to evaluate the implementation of cryptococcal antigen (CRAG) screening and preemptive anti-fungal therapy of HIV-infected persons entering antiretroviral therapy (ART)…
- Conditions
- Cryptococcal Meningitis, Cryptococcus Neoformans, Cryptococcosis
- Trial name
- ORCAS (NCT01535469)
- Testing
- Fluconazole
- Where
- 2 sites in Uganda
- Volunteers
- 3,049 people
- Sponsor
- University of Minnesota
Obesity
SMARTer Weight Loss Management
The SMARTer trial will be a three-arm, randomized controlled non-inferiority trial that compares the optimized, adaptive SMARTer intervention, fixed DPP, and Self-Guided (Control).
- Trial name
- SMARTer (NCT05861973)
- Testing
- Adaptive SMARTer intervention (SMARTer), Diabetes Prevention Program (DPP), Self-Guided Treatment (Self-Guided)
- Where
- United States
- Volunteers
- 492 people
- Sponsor
- Florida State University
Chronic Pain
Implementation and Evaluation of a Stepped-Care Mental Health Treatment Program for Patients With Chronic Pain
Chronic pain affects nearly 20% of Canadians, and sixty percent or more of individuals with chronic pain are also struggling with mental health or substance use disorders (referred to as complex chronic pain, or CCP, patients).
- Trial name
- NCT04885192
- Testing
- Stepped-Care Model
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University Health Network, Toronto
Exercise, Cancer
Implementation of the 3-steps Assess-Advise-Refer Exercise (FitARise) Protocol as a Standard Practice in Cancer Care
This study proposes to evaluate the process and outcome of an implementation program designed to implement the American College of Sports Medicine (ACMS)-recommended exercise assessment, advice, and referral instruction as…
- Trial name
- NCT07210905
- Testing
- 3-step Assess-Advice-Refer
- Where
- 8 sites in Hong Kong
- Volunteers
- 1,800 people
- Sponsor
- The University of Hong Kong
Trauma
Evaluation of the Effectiveness of a Regional Trauma Care System for the Treatment of Patients With Severe Trauma
Severe trauma imposes a heavy burden to society and family because of its high mortality and disability rate. Based on the implementation plan of "one region", "two links", and "three teams", the Trauma Medicine Center of Peking…
- Trial name
- NCT05799170
- Testing
- regional trauma care
- Volunteers
- 3,200 people
- Sponsor
- Peking University People's Hospital
Congenital Heart Disease
Online Support 4 CHD Kids & Caregivers
This study will evaluate a virtual mental health parenting stepped-care intervention (I-InTERACT-North) to determine if the program works to improve positive parenting skills and child behaviour among families with children born…
- Trial name
- NCT06075251
- Testing
- I-InTERACT-North
- Where
- Canada
- Volunteers
- 382 people
- Sponsor
- The Hospital for Sick Children
HIV/AIDS
Managed Problem Solving for ART Adherence and HIV Care Retention Delivered by Community Health Workers
The Managed Problem Solving (MAPS) behavioral intervention is an EBP for behavior change in people living with HIV (PLWH). The investigators propose that MAPS can be delivered by trained Community Health Workers (CHWs).
- Trial name
- NCT04560621
- Testing
- Managed Problem Solving (MAPS)
- Where
- 10 sites in United States
- Volunteers
- 210 people
- Sponsor
- University of Pennsylvania
Sleep Deprivation, Critical Illness
Sleep Harmonization Via Bundled Team-Based Interventions in the ICU
SHANTI-ICU compares the effectiveness of two evidence-based multicomponent ICU sleep promotion bundles on delirium and patient-reported sleep quality in critically ill adults. Bundle A is a non-pharmacologic strategy.
- Conditions
- Sleep Deprivation, Critical Illness, Sleep-Wake Disorders, Bundle Care
- Trial name
- SHANTI-ICU (NCT07840560)
- Testing
- Nighttime noise & light reduction, Clustering patient-care interactions, Non-pharmacologic sleep aids
- Where
- 8 sites in United States, Puerto Rico
- Volunteers
- 62,500 people
- Sponsor
- University of California, San Diego