Clinical trials: Sterility
Infertility, Anovulation
Efficacy Study of the OV-Watch™ Personal Fertility Monitor for Women Using Clomiphene Citrate.
The purpose of this study is to evaluate the effectiveness of the OV-Watch to predict ovulation while women are taking clomiphene citrate.
- Conditions
- Infertility, Anovulation, Polycystic Ovary Syndrome
- Trial name
- NCT00239603
- Testing
- OV-Watch
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Polycystic Ovary Syndrome
Cinnamon and COH in PCOS Women Underdoing IVF/ICSI Cycles
In patients with polycystic ovary syndrome, insulin resistance increases, and since the extracts from cinnamon reduces insulin resistance by two mechanisms (1- increasing activation of the IRS/PI-3 kinase insulin signaling…
- Trial name
- NCT06199024
- Testing
- Oral cinnamon supplementation
- Where
- Iran
- Volunteers
- 80 people
- Sponsor
- Royan Institute
Male Infertility, Testicular Diseases
Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm
Our data indicate that environmental exposure to the heavy metal lead are more widespread than currently appreciated and that such exposures are associated with the production of human male subfertility.
- Conditions
- Male Infertility, Testicular Diseases, Urologic and Male Genital Diseases, Lead Poisoning
- Trial name
- NCT00012480
- Where
- 3 sites in United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility, Female, Poor Response to Ovulation Induction
Does DHEA IVF Outcomes in Poor Responders?
This study is a RCT to examine whether DHEA is capable of improving results for poor responders to ovarian stimulation during IVF treatment
- Trial name
- DHEA (NCT04066478)
- Testing
- Dehydroepiandrosterone
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- Homerton University Hospital NHS Foundation Trust
Infertility
Efficacy Study of Granulocyte-macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF
This study is to assess whether addition of 2 ng/ml GM-CSF into a specific culture medium will increase the chance of a pregnancy after in vitro fertilisation.
- Trial name
- GM-CSF (NCT00565747)
- Testing
- Test culture, Control culture
- Where
- 14 sites in Denmark, Sweden
- Volunteers
- 1,332 people
- Sponsor
- Origio A/S
Infertility, Female
Can Virtual Reality Technology Improve the Patient Experience in Oocyte Retrieval?
A non-pharmacological, non-blinded, randomized cohort study that will investigate the effect of Virtual Reality technology on the patient experience during oocyte retrieval.
- Trial name
- NCT05826938
- Testing
- Virtual reality technology
- Where
- Denmark
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility, Male
Role of Nutritional Support in Idiopathic Male Infertility
Approximately 100 males with idiopathic infertility and oligo- and/or astheno- and/or and/or teratozoospermia and fertile woman will take a Test dietary supplement (TDS), containing carnitine, vitamins and trace elements (active…
- Trial name
- NCT03588949
- Testing
- Dietary Supplement with L-carnitine (FertilHom), Control Dietary Supplement
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- NATURAmedicatrix Sàrl
Infertility
Application of Two Different Synthetic Sequential Media for the Human IVF-Embryo Transfer (IVF-ET) Program
Quality-controlled commercial media have been used in many in-vitro fertilization (IVF) laboratories. However, commercial media are costly and difficult to compare directly because their exact compositions are not clearly…
- Trial name
- NCT01356238
- Testing
- MRC media, Sydney IVF media
- Where
- South Korea
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Maria Fertility Hospital
Metabolic Diseases, Infertility
Study to Create Potential Cell-Based Therapies to Treat Human Disease and Disability
This is a research study in which your cells will be used for somatic cell nuclear transfer (SCNT), and/or genetic reprogramming research which may result in the production of stem cell lines.
- Trial name
- NCT00628199
- Testing
- Improving the scientific process of human cell reprogramming
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Infertility, Genetic Disease
Follow-up With Preimplantation Genetic Testing Patients
The main purpose of this study is to perform longitudinal evaluations of clinical outcomes and personal perspectives following utilization of preimplantation genetic testing (PGT).
- Conditions
- Infertility, Genetic Disease, IVF
- Trial name
- NCT04477863
- Testing
- Follow-up Interview
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Genomic Prediction Inc.
Prostate Cancer
Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer
RATIONALE: Nerve-sparing radical prostatectomy with nerve grafting followed by standard therapies for erectile dysfunction may be effective in helping patients with prostate cancer improve sexual satisfaction and quality of life.
- Trial name
- NCT00080808
- Testing
- Alprostadil (E1), Papaverine, Phentolamine mesylate
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- M.D. Anderson Cancer Center
Infertility, Ovulation Induction
A Clinical Trial to Determine the Effect of Lutropin Alfa on Embryo Quality and Implantation Rate in Advanced Reproductive Age
This is a multicentric, open, randomized, comparative trial aimed to assess the influence of recombinant luteinizing hormone (r-LH) supplementation during controlled ovarian stimulation (COS) in advanced reproductive age in terms…
- Trial name
- NCT01075815
- Testing
- Recombinant human luteinizing hormone (rhLH), Recombinant follicle-stimulating hormone (rFSH)
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Oocyte Donation, Infertility, Female
Transfer Strategy in an Oocyte Donation Programme
It has been previously shown that although the activation of the embryonic genome can begin as early as two days of initiation of the embryonic development (D2), it is expressed on day 3 (D3).
- Conditions
- Oocyte Donation, Infertility, Female, Embryo Transfer
- Trial name
- NCT03088735
- Testing
- Blastocyst-stage embryo transfer strategy, Cleavage-stage embryo transfer strategy
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Fundacion Dexeus
Infertility
Dual Ovarian Stimulation in the Same IVF/ICSI Cycles for Treatment of Poor Ovarian Responders
This study is a prospective before \& after clinical trial to investigate the efficacy of double stimulations during both the follicular and luteal phases in patients with poor ovarian response undergoing IVF and intracytoplasmic…
- Trial name
- NCT02732808
- Testing
- Ovulation stimulation
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Royan Institute
Infertility, Female, Ovarian Reserve
hCG Priming in Women With Low Ovarian Reserve
The aim of this trial is to examine the possible effects of hCG administration for eight weeks prior to IVF/ICSI in women with low ovarian reserve.
- Conditions
- Infertility, Female, Ovarian Reserve, In Vitro Fertilization
- Trial name
- NCT04643925
- Testing
- Ovitrelle
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infertile Women Undergoing Assisted Reproductive Technology (ART)
A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Ovarian Stimulation
To demonstrate the comparative safety and efficacy of Cetrotide® 3 milligram (mg) and Antagon™ in the inhibition of a premature luteinizing hormone (LH) surge in women undergoing ovarian stimulation with recombinant human…
- Trial name
- NCT00298025
- Testing
- Cetrotide®, Antagon ™, Recombinant human follicle stimulating hormone (r-hFSH)
- Volunteers
- 185 people
- Sponsor
- EMD Serono
Infertility
Type of Gonadotropin and Embryo Kinetics of Development
The study is proposed to determine the effect of three types of gonadotropins that are currently used in protocols of controlled ovarian stimulation in women undergoing in vitro fertilization techniques on the kinetics of…
- Trial name
- PEM-ESD (NCT02402192)
- Testing
- Corifollitropin alfa
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- IVI Madrid
Infertility, Female, Clomiphene Citrate
Effects of Clomiphene Citrate Ovulation Induction on Frozen Embryo Transfer
Clomiphene citrate has been widely used for treatment of infertility for decades. Although its anti-estrogenic effects leads to low pregnancy rate, clomiphene citrate is still a first-line treatment for ovulation induction…
- Trial name
- NCT03309436
- Testing
- Clomiphene Citrate protocol, Procedure
- Where
- China
- Volunteers
- 360 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility, Female
Parental Attitudes in Invitro Fertilization
The relationship between revelation of mode of conception and child behavior is not known
- Trial name
- NCT04126109
- Testing
- questionaire
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aljazeera Hospital
Infertility
Follicular Activation in Poor Responders
This study aims to assess whether activation of primordial follicles through ovarian cortex fragmentation may increase the number of antral follicles present in the ovary of patients with diminished ovarian reserve.
- Trial name
- FAPPOR (NCT02354963)
- Testing
- In vitro fragmentation of the ovarian tissue
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- César Díaz García