Clinical trials: Steroid
Plaque Psoriasis
Ammonium Lactate Lotion 12% (Lac-hydrin®) and Halobetasol Propionate Ointment 0.05% (Ultravate®) in the Treatment and Maintenance of Psoriasis
The purpose of this study is to determine whether the combinational use of ammonium lactate lotion 12% (Lac-Hydrin) and halobetasol propionate ointment 0.05% (Ultravate) is safe and effective in the initial treatment and…
- Trial name
- NCT01111123
- Testing
- Lac-Hydrin lotion (ammonium lactate lotion 12%) ; UItravate ointment (halobetasol propionate ointment 0.05%)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Alopecia Totalis, Alopecia Universalis
Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata
Systemic Pulse Glucocorticoids have been shown to be effective in widespread Alopecia areata but not the totalis, universalis or ophiasic type.
- Conditions
- Alopecia Totalis, Alopecia Universalis, Ophiasic Alopecia
- Trial name
- NCT01167946
- Testing
- methylprednisolone sodium succinate
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- King Saud University
To Assess the Changes in Markers of Bone Turnover Over a Six Month Period After Epidural Steroid Inject, To Assess the Changes in Bone Mineral Density
Effect of Epidural Steroid Injection on Bone Mineral Density in Postmenopausal Women
To evaluate for the effect of corticosteroid epidural injections on bone mineral density in postmenopausal women. Candidates for the study: Post menopausal women between the ages of 55 and 80. No history of bone disease.
- Trial name
- NCT00941473
- Testing
- Triamcinilone (kenalog)
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Acute Graft-versus-host Disease
Safety of Itacitinib in Combination With Corticosteroids for Treatment of Steroid-Naive Acute Graft-Versus-Host Disease in Japanese Subjects
The purpose of this study is to assess the safety and tolerability of itacitinib in combination with corticosteroids in Japanese subjects with Grades II to IV acute graft-versus-host disease (aGVHD).
- Trial name
- NCT03497273
- Testing
- Itacitinib, Corticosteroid
- Where
- 17 sites in Japan
- Volunteers
- 14 people
- Sponsor
- Incyte Corporation
High-grade Gliomas (HGG)
Steroid Avoidance, Dexamethasone, and RAGE Inhibition for Perioperative Cerebral Edema Management in High-Grade Gliomas
The purpose of this study is to learn whether two alternatives to standard steroid treatment can safely control swelling around a brain tumor after surgery.
- Trial name
- NCT07694089
- Testing
- Dexamethasone, Azeliragon
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Akshitkumar MIstry
Fever, Labor Pain
Maternal Epidural Steroids and Hyperthemia
The purpose of this study is to look to see if adding steroids to an epidural reduces the chances of having a fever in labor, and protects the baby from exposure to inflammation.
- Conditions
- Fever, Labor Pain, Complication of Anesthesia During Pregnancy, Unspecified
- Trial name
- NCT02212210
- Testing
- Methylprednisolone, Normal saline
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Medical University of South Carolina
Immune Thrombocytopenia, Blood Coagulation Disorders
The Combination of Sitagliptin and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia
Randomized, open-label, multicenter study to compare the efficacy and safety of combination of Sitagliptin and danazol versus danazol for the treatment of adults with steroid-resistant/relapse immune thrombocytopenia (ITP).
- Conditions
- Immune Thrombocytopenia, Blood Coagulation Disorders, Thrombocytopenia, Physiological Effects of Drugs
- Trial name
- NCT05353673
- Testing
- Sitagliptin, Danazol
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University People's Hospital
Cushing's Syndrome, Postoperative
Contralateral Adrenal Volume Predicts Duration of Postoperative Steroid Replacement Therapy in Non-ACTH-dependent Hypercortisolism
To identify preoperative factors influencing the duration of steroid replacement therapy after adrenalectomy/adrenal-sparing surgery in patients with non-ACTH-dependent hypercortisolism.
- Conditions
- Cushing's Syndrome, Postoperative, Glucocorticoid, Prediction
- Trial name
- NCT07282223
- Testing
- observational diagnostic model development
- Where
- China
- Volunteers
- 121 people
- Sponsor
- Peking University First Hospital
Pediatric Disorder, Esophageal Diseases
Role of Topical Steroid Injection With Refractory Benign Esophageal Stricture Endoscopic Dilatation in Children
This clinical trial study included 21 children with refractory benign esophageal strictures. Upper GI endoscopy performed up to the area of stricture, esophageal dilatation done, endoscopy repeated, and steroid injected…
- Conditions
- Pediatric Disorder, Esophageal Diseases, Esophageal Stricture
- Trial name
- ISIs (NCT06514079)
- Testing
- Esophageal dilatation with steroids injection
- Where
- Egypt
- Volunteers
- 21 people
- Sponsor
- Mohammad Daboos
Chronic Low Back Pain
Epidural Study of Patients With Chronic Lower Back Pain
The purpose of this study is to examine 4 different epidural dosing regimes of local anaesthetic solution in a series of 3 epidural injections over a period of 12 months to determine the optimum dose of anaesthetic solution for…
- Trial name
- NCT00887003
- Testing
- Bupivacaine, Depo-Medrol
- Where
- Canada
- Volunteers
- 252 people
- Sponsor
- McMaster University
Mild and Moderate Atopic Dermatitis Patients, Atopic Dermatitis (AD)
Clinical Trial of an Ointment in Patients With Mild and Moderate Atopic Dermatitis
Atopic dermatitis (AD) is a chronic skin disorder, which negatively impacts up to 20% children and 3% adults in the world. The main AD treatments aim to regress clinical manifestations, improve and restore skin lesions.
- Trial name
- NCT07653386
- Testing
- S.formosum-containing ointment, commercial moisturizer
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- VinUniversity
Mild Autonomous Cortisol Secretion (MACS), Autonomous Cortisol Secretion (ACS)
Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS
single-center, randomized, double-blind, placebo-controlled Phase 2 study to evaluate safety and efficacy of overnight metyrapone in patients with MACS.
- Trial name
- NCT07138274
- Testing
- Metyrapone 250 mg Oral Tablets
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Peripheral Nerve Stimulation, Genicular Nerves
Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study
To compare the effects of the following types of therapy on knee range of motion when given to patients with chronic knee pain: A standard steroid injection Peripheral nerve stimulation (PNS) therapy in combination with a…
- Conditions
- Peripheral Nerve Stimulation, Genicular Nerves, Chronic Knee Pain
- Trial name
- NCT06004882
- Testing
- PNS therapy, Triamcinolone, Bupivacaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Asthma, Obesity
Examining the Link Between Obesity, Inflammation, and Response to Asthma Medications
Asthma is a common, long-term disease that is caused by inflammation of the airways. Inflammation also plays a role in obesity and may affect the way a person responds to asthma medication.
- Trial name
- NCT00557180
- Testing
- Beclomethasone dipropionate HFA, Tiotropium bromide, Salmeterol xinafoate
- Where
- 10 sites in United States
- Volunteers
- 33 people
- Sponsor
- National Jewish Health
Cataract Extraction, Cataract
Clinical Study to Evaluate the Efficacy and Tolerability of an Anti-inflammatory/Antibiotic Treatment Following Ocular Cataract Extraction
Cataract is an ophthalmic disease that usually affects the elderly population. Cataract surgery with phaco-emulsification is now the most frequently performed intraocular surgical procedure in the developed world.
- Trial name
- NCT02973880
- Testing
- NETILDEX™ ophthalmic gel, NETILDEX™ eye drops solution
- Where
- 7 sites in Germany, Italy and 1 more
- Volunteers
- 180 people
- Sponsor
- SIFI SpA
Chronic GVHD
Front Line Ibrutinib Without Corticosteroids for Newly Diagnosed Chronic Graft-versus-Host Disease
Background: Chronic Graft Versus Host Disease (cGVHD) can occur after a person has had a stem cell or bone marrow transplant. In cGVHD, the donor cells attack the recipient's body.
- Trial name
- NCT04294641
- Testing
- Ibrutinib, ECG, PFT's
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Plantar Fasciitis
Comparing Steroid Injections and Platelet Rich Plasma Injections in the Treatment of Plantar Fasciitis
In cases of Plantar Fasciitis not responding to conservative management, minimally invasive techniques may be used. These include platelet rich plasma injections and corticosteroid injections.
- Trial name
- NCT01957631
- Testing
- Corticosteroid injection (Bupivacaine and Depo Medrol), Platelet rich plasma injection
- Where
- Bahrain
- Volunteers
- healthy volunteers welcome
- Sponsor
- King Hamad University Hospital, Bahrain
Acute Graft Versus Host Disease
Evaluation of Umbilical Cord-Derived Wharton's Jelly Stem Cells for the Treatment of Acute Graft Versus Host Disease
This study evaluates the safety and effectiveness of two different doses of umbilical cord derived, ex-vivo cultured and expanded Wharton's jelly mesenchymal stem cells (MSCTC-0010) in the treatment of acute Graft versus Host…
- Trial name
- NCT03158896
- Testing
- MSCTC-0010 Dose Escalation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Kansas Medical Center
Thrombocytopenia
Efficacy of Helicobacter Pylori Eradication, Anti-D and Danazol Combination in Steroid Dependant or Refractory Immune Thrombocytopenia (ITP)
Proportion who would avoid splenectomy at 6 months of follow up
- Trial name
- NCT01162941
- Testing
- Steroid refractory ITP
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Cooperative Study Group A for Hematology
Ethmoid Sinusitis
Sinopsys® Lacrimal Stent Indicated for Sinus Irrigation
The primary objective is to evaluate clinical data related to the safety and performance of the Sinopsys® Lacrimal Stent.
- Trial name
- NCT03304951
- Testing
- Sinopsys® Lacrimal Stent
- Where
- Czechia
- Volunteers
- 8 people
- Sponsor
- Sinopsys Surgical
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