Clinical trials: Steroid
Hemiplegic Shoulder Pain
Suprascapular Nerve Block Versus Intraarticular Steroid Injection in Hemiplegic Shoulder Pain
Suprascapular nerve block versus(vs) intra-articular steroid injection in the management of hemiplegic shoulder pain (HSP): a randomised, double blinded, controlled trial BACKGROUND Hemiplegic shoulder pain (HSP) is a common…
- Trial name
- NCT04128605
- Testing
- Suprascapular nerve block (SSNB), Intraarticular shoulder steroid injection (IAS)
- Where
- Malaysia
- Volunteers
- 86 people
- Sponsor
- University of Malaya
Swallowing
Randomized Controlled Trials of the Effects of Decadron on Swallowing, Airway, and Arthrodesis
Anterior cervical discectomy and fusion with or without decompression is a well-established surgical treatment for spine patients with the appropriate indications.
- Trial name
- NCT01065961
- Testing
- Decadron, Saline
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Albany Medical College
Chronic Graft-Versus-Host Disease, Acute Graft-Versus-Host Disease
Donor Regulatory T Cells Infusion in Patients With Chronic Graft-versus-host Disease (GVHD)
The immune system has offensive and defensive capacities. In bone marrow transplantation, offensive cells in the donor grafts may attack host's organs, leading to a complication known as Graft versus Host Disease (GVDH).
- Conditions
- Chronic Graft-Versus-Host Disease, Acute Graft-Versus-Host Disease, Steroid Refractory Graft-Versus-Host Disease
- Trial name
- NCT01903473
- Testing
- Rapamycin, T regulatory cells
- Where
- 2 sites in Belgium
- Volunteers
- 19 people
- Sponsor
- University of Liege
Lumbosacral Radicular Pain
The Incidence of the Intravascular Injection During S1 Transforaminal Epidural Steroid Injection in Two Approaches: Anteroposterior Versus Oblique
Lumbosacral transforaminal epidural steroid injection (TFESI) is helpful for the treatment of lumbosacral radicular pain, but in case of intravascular injection, infrequently serious complication can be developed.
- Trial name
- NCT01926470
- Testing
- anteroposterior approach group, oblique approach group
- Where
- South Korea
- Volunteers
- 201 people
- Sponsor
- Yonsei University
Congenital Cystic Adenomatoid Malformation
Prenatal Steroids for Treatment of Congenital Cystic Adenomatoid Malformations (CCAM)
Congenital cystic adenomatoid malformations (CCAMs) are theorized to be growing immature lung tissue. Administration of maternal steroids in the mid-trimester may stop the growth or decrease the size of the CCAM, thus increasing…
- Trial name
- CCAM Steroids (NCT00670956)
- Testing
- Betamethasone
- Where
- 3 sites in United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Endometrioma
Post Operative Continuous Active Combination Sex Steroids for the Prevention of Recurrent Endometrioma Formation
The aim of this study is to determine whether or not continuous combined oral contraceptive pills (COCP's) decrease the risk of recurrent endometrioma formation.
- Trial name
- NCT00999479
- Testing
- Norethindrone acetate and ethinyl estradiol tablets, USP
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Alopecia Areata
Sodium Valproate-loaded Nanospanlastics in Patchy Alopecia Areata in Comparison to Topical Steroids
the aim of this study is to assess the efficacy and safety of sodium valproate-loaded nanospanlastic in the treatment of patchy AA, in comparison to conventional therapy with topical steroids
- Trial name
- NCT05017454
- Testing
- the optimized sodium valproate-loaded nanospanlastic dispersion, mometasone furoate lotion
- Where
- Egypt
- Volunteers
- 67 people
- Sponsor
- Kasr El Aini Hospital
Disorder Related to Renal Transplantation
Phase IV Study to Evaluate Calcineurin Inhibitor Reduced, Steroid Free Immunosuppression After Renal Transplantation
Current practice of immune suppressive standard therapy after renal transplantation in non-risk patients is a triple therapy consisting of steroids, a calcineurin inhibitor and MMF.
- Trial name
- Harmony (NCT00724022)
- Testing
- Basiliximab, Tacrolimus, MMF, Prednisolon, Basiliximab, Tacrolimus, MMF, Tacrolimus, MMF, rATG
- Where
- 25 sites in Germany
- Volunteers
- 600 people
- Sponsor
- University Hospital Freiburg
Percutaneous Nephrolithotomy (PCNL), Postoperative Pain
The Effect of NSAID Steroid Therapy for PGE2 Level and Analgesia After Percutaneous Nephrolithotomy Surgery
The goal of this clinical trial is to learn if combination of NSAID-steroid can decrease the PGE2 level and postoperative pain after percutaneous nephrolithotomy surgery.
- Trial name
- BUPARDEX (NCT06604598)
- Testing
- IBU-PCT-DEX
- Where
- Indonesia
- Volunteers
- 45 people
- Sponsor
- Universitas Jenderal Soedirman
Heart Transplantation
A Study of CellCept (Mycophenolate Mofetil) in Combination Therapy in Heart Transplant Patients.
This study will investigate the efficacy and safety of CellCept (1.5-2g/day po), in combination with a standard care regimen of cyclosporine A (trough level 150-200ng/mL) and steroids, in patients receiving a heart transplant.
- Trial name
- NCT02091414
- Testing
- mycophenolate mofetil (MMF), cyclosporine A (CsA), corticosteroids
- Where
- 3 sites in China
- Volunteers
- 36 people
- Sponsor
- Hoffmann-La Roche
Lumbosacral Radiculopathy
Caudal Versus S1 Transforaminal Epidural Steroid Injection for the Treatment of Unilateral S1 Radiculopathy
To compare the efficacies of two different interventional techniques (Caudal epidural steroid injection and S1 transforaminal epidural steroid injection) for the treatment of unilateral S1 radiculopathy.
- Trial name
- NCT05711121
- Testing
- Transforaminal epidural steroid injection, Caudal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Effects of Banned Substances
Effects of Banned Substances on Some Metabolic Functions in Male Amateur Athletes
The aim of this study was to investigate the effects of banned substances on some metabolic functions in male athletes in order to raise awareness among individuals who use these substances by highlighting the potential harms of…
- Trial name
- NCT06823011
- Testing
- blood collection
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hitit University
Carpal Tunnel Syndrome
Efficacy of Combined Ultrasound Guided Steroid Injection and Splinting in Patients With Carpal Tunnel Syndrome
To compare the effectiveness of ultrasound guided-steroid injection plus splinting to that of steroid injection alone using clinical and electrophysiological parameters in patients with carpal tunnel syndrome
- Trial name
- NCT02708693
- Testing
- Triamcinolone Acetonide, thermoplastic wrist splint, lidocaine hydrochloride
- Volunteers
- 52 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Graft vs Host Disease
Mesenchymal Stem Cells as First Treatment Line for Resistant Acute Graft Versus Host Disease
Steroids are still the first line treatment for established severe acute-graft-versus-host-disease (aGVHD), with a response rate of 30-50%, and there is no established and effective therapy for severe steroid-refractory (aGVHD).
- Trial name
- NCT02770430
- Testing
- mesenchymal stem cells, conventional treatment
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Obstructive Pulmonary Disease, Emphysema
Inhaled Steroid Reduces Systemic Inflammation in COPD
Systemic inflammation is present in chronic obstructive pulmonary disease (COPD), which has been linked to cardiovascular morbidity and mortality.
- Conditions
- Chronic Obstructive Pulmonary Disease, Emphysema, Chronic Bronchitis
- Trial name
- NCT00175565
- Testing
- inhaled fluticasone 500 mcg b.i.d.
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Asthma
Small Particle Steroids in Refractory Asthma
The purpose of this study is to determine whether an inhaled steroid with a small particle size can be an additional treatment option in patients with refractory eosinophilic asthma.
- Trial name
- SPIRA (NCT01171365)
- Testing
- Ciclesonide
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Nottingham
Congenital Adrenal Hyperplasia, Adrenal Insufficiency
Evaluation of Circadian Hormonal Balance: LC-MS/MS Measurement of Salivary and Serum Steroids in Patients With Congenital Adrenal Hyperplasia
In congenital adrenal hyperplasia (CAH), lifelong hormone replacement therapy is required to treat adrenal insufficiency and to reduce elevated androgen levels. This is essential to ensure "normal" growth and puberty.
- Conditions
- Congenital Adrenal Hyperplasia, Adrenal Insufficiency, Hyperandrogenism; 21-hydroxylase Deficiency
- Trial name
- MASSALIVE (NCT07718230)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nephrotic Syndrome in Children
Predictors of Steroid Response in Childhood Nephrotic Syndrome
Retrospective study of predictors of steroid response in childhood nephrotic syndrom
- Trial name
- NCT06130631
- Volunteers
- 79 people
- Sponsor
- Maha Radwan
Carpal Tunnel Syndrome
Ultrasound-guided PRP Versus Steroid Injections in Management of Carpal Tunnel Syndrome
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel.
- Trial name
- NCT04434105
- Testing
- platlet rich plasma (PRP), Triamcinolone Acetonide, Saline
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Allogeneic Hematopoietic Stem Cell Transplantation
A Dose-Finding Study of Vedolizumab for Treatment of Steroid-Refractory Acute Intestinal Graft-Versus-Host Disease (GvHD) in Participants Who Have Undergone Allogeneic Hematopoietic Stem Cell Transplantation (Allo-HSCT)
The purpose of this study is to assess the initial activity, tolerability, safety and to identify a recommended dose and regimen of vedolizumab intravenous (IV) administered for treatment of steroid-refractory acute intestinal…
- Trial name
- NCT02993783
- Testing
- Vedolizumab
- Where
- 15 sites in United States, Belgium and 3 more
- Volunteers
- 17 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
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