Clinical trials: Steroid
Chronic Sinusitis
A Clinical Study to Evaluate the Safety and Effectiveness of Novabel Bioabsorbable Steroid-releasing Stent for the Chronic Sinusitis
The goal of this clinical trial is to learn about the safety and effectiveness of Novabel bioabsorbable steroid-releasing stent in chronic sinusitis.
- Trial name
- NCT06020690
- Testing
- bioabsorbable steroid-releasing stent
- Where
- China
- Volunteers
- 93 people
- Sponsor
- Enlight Medical Technologies (Shanghai) Co., Ltd
Bipolar Disorder, Circadian Rhythm
Effects of Sex Hormones on Circadian Rhythm in Men and Women
For many years researchers have been trying to better understand the regulation of sleep and activity by studying circadian (daily) rhythms of human beings.
- Conditions
- Bipolar Disorder, Circadian Rhythm, Depressive Disorder
- Trial name
- NCT00001285
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Antiphospholipid Syndrome
Steroids and Antiphospholipid Syndrome- Related Pregnancy Loss
Does the addition of steroids during the first trimester to the standard aspirin + heparin treatment reduce the miscarriage rates in women with antiphospholipid antibodies and recurrent first trimester miscarriage in those who…
- Trial name
- NCT00180778
- Testing
- Low dose steroids
- Where
- United Kingdom
- Sponsor
- Imperial College London
Trigger Point Pain, Myofascial, Lumbar Radiculopathy
The Effect of the Presence of Active Trigger Points in the Muscles Innervated by the Affected Nerve Roots on the Treatment Results of Transforaminal Epidural Steroid Injection in Patients With Lumbar Radiculopathy.
The association between lumbosacral radiculopathy and the ipsilateral gluteal trigger point has been demonstrated in 74% of previous studies in patients with chronic low back pain.
- Trial name
- NCT05535010
- Testing
- Transforaminal epidural steroid injection(TFESI)
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Marmara University
Lower Abdominal Oncologic Surgery
Epidural Steroids With Intrathecal Nalbuphine for Lower Abdominal Oncologic Surgery
Intraoperative pain, nausea, vomiting, hypotension, bradycardia are known side effects during lower abdominal surgery under spinal anesthesia, Time to 2 segment regression of sensory block and duration of effective analgesia…
- Trial name
- NCT03276325
- Testing
- Dexamethasone-nalbuphine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Asthma, Obesity
Examining the Link Between Obesity, Inflammation, and Response to Asthma Medications
Asthma is a common, long-term disease that is caused by inflammation of the airways. Inflammation also plays a role in obesity and may affect the way a person responds to asthma medication.
- Trial name
- NCT00557180
- Testing
- Beclomethasone dipropionate HFA, Tiotropium bromide, Salmeterol xinafoate
- Where
- 10 sites in United States
- Volunteers
- 33 people
- Sponsor
- National Jewish Health
Graft vs Host Disease
Sirolimus as Treatment of Steroid-Refractory or Steroid-Dependent Chronic Graft-Versus-Host Disease
To study the effectiveness of an immunosuppressive drug sirolimus, in the treatment of chronic graft versus host disease in combination with prednisone.
- Trial name
- NCT00388362
- Testing
- Sirolimus, Prednisone
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Stanford University
Low Back Pain, Radiculopathy
The Effect of Comorbid Psychiatric Conditions on Results of Transforaminal Epidural Steroid Injection
Low back pain (LBP) and radiculopathic pain are a major socio-economic problem affecting all age groups. 70% of people consult a doctor at least once in their life due to LBP.
- Trial name
- NCT03821350
- Testing
- Information leaflet
- Volunteers
- 166 people
- Sponsor
- Hitit University
De Quervain Syndrome
Splint Versus Steroid Randomized Trial
The primary aim is to compare the effectiveness of splinting versus steroid injection in improving the DASH scores in participants diagnosed with De Quervain's tenosynovitis over a period of 6 months.
- Trial name
- NCT05165875
- Testing
- Hydrocortisone-Lidocaine, Splint
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Steroid Dependent Crohn's Disease
A Phase 2a Study to Evaluate the Safety, Tolerability and Efficacy of Cannabidiol as a Steroid-sparing Therapy in Steroid-dependent Crohn's Disease Patients
Treatment will start with dose escalation in addition to Standard of Care (steroid therapy with or without additional therapies) .
- Trial name
- NCT04056442
- Testing
- Cannabidiol , synthetic form
- Where
- 3 sites in Israel
- Volunteers
- 15 people
- Sponsor
- Stero Biotechs Ltd.
Steroid-refractory Acute Graft Versus Host Disease
Study of Efficacy and Safety of Ruxolitinib in Patients With Grade II to IV Steroid-refractory Acute Graft vs. Host Disease
The purpose of this study is to assess the efficacy and safety of ruxolitinib therapy in Chinese adults and adolescents (≥ 12 years old) with Grade II-IV steroid-refractory acute graft versus host disease (SR-aGvHD).
- Trial name
- NCT06462469
- Testing
- Ruxolitinib
- Where
- 9 sites in China
- Volunteers
- 36 people
- Sponsor
- Novartis Pharmaceuticals
Giant Cell Arteritis
A Study to Evaluate Efficacy and Safety of Subcutaneous Abatacept With Steroid Treatment Compared to Steroid Treatment Alone in Adults With Giant Cell Arteritis (GCA)
To investigate the safety and efficacy of abatacept with steroid treatment in comparison to steroid treatment alone in up to a 28 week taper of steroid treatment to sustain remission of Giant Cell Arteritis in adults.
- Trial name
- NCT03192969
- Testing
- Abatacept, Glucocorticoid Treatment
- Where
- 99 sites in United States, Australia and 19 more
- Sponsor
- Bristol-Myers Squibb
Enuresis, Obstructive Sleep Apnea
Intranasal Steroids for the Treatment of Nocturnal Enuresis With Associated Obstructive Sleep Apnea
Enuresis (E) or bedwetting is a common pediatric complaint, and recent research has discovered a link with obstructive sleep apnea (OSA).
- Conditions
- Enuresis, Obstructive Sleep Apnea, Sleep Disordered Breathing
- Trial name
- NCT01861145
- Testing
- Bed Alarm, Nasonex
- Where
- 2 sites in Canada
- Sponsor
- University of Alberta
Adrenal Hyperplasia, Congenital
Growth Hormone (GH) in Congenital Adrenal Hyperplasia
Congenital adrenal hyperplasia (CAH) is a genetic rare disease, which alters the adrenal production of gluco and mineralo corticoids. The treatment consists in supplementing children using hydrocortisone.
- Trial name
- OPALE GH (NCT03162172)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Hospices Civils de Lyon
Dexamethasone, Glucocorticoids
High vs Low Dose Dexamethasone on Complications in the Immediate Postoperative Phase After Mastectomy
The aim of this study is to investigate the effect of a single preoperative high-dose steroid injection on complications in the immediate postoperative phase after breast cancer surgery, with removal of the breast (mastectomy).
- Conditions
- Dexamethasone, Glucocorticoids, Mastectomy, Breast Cancer
- Trial name
- DEX-MAS (NCT03125941)
- Testing
- Dexamethasone
- Where
- Denmark
- Volunteers
- 130 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
GVHD, Acute
Decidua Stroma Cells for Steroid Resistent Acute Graft-versus-host Disease After Allo-HSCT
A randomized (1:1) phase II open label study of DSC compared to Investigator choice Best Available Therapy (BAT) in allogeneic hematopoietic stem cell transplant recipients with Grades II-IV steroid refractory acute graft vs.
- Trial name
- 2017-00355 (NCT04118556)
- Testing
- Decidua Stroma Cells (DSC), Best available Treatment (BAT)
- Where
- 4 sites in Denmark, Norway and 1 more
- Volunteers
- 12 people
- Sponsor
- Mats Remberger
Central Retinal Vein Occlusion, Branch Retinal Vein Occlusion
Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions
The aim of this study is to develop a less risky, yet effective and more sustainable treatment for retinal vein occlusions than the current commonly used approach of repeated intravitreal triamcinolone acetonide (Kenalog)…
- Trial name
- NCT00500045
- Testing
- nicotinic acid
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Palo Alto Medical Foundation
Disorder Related to Renal Transplantation
A Phase II Study of Belatacept (BMS-224818) With a Steroid-free Regimen in Subjects Undergoing Kidney Transplantation
The purpose of this clinical research study is to learn if belatacept (BMS-224818) is expected to show acceptable rates of acute rejection (AR) in steroid-free belatacept-based immunosuppressive regiments compared to a similar…
- Trial name
- NCT00455013
- Testing
- Thymoglobulin, Belatacept, Sirolimus
- Where
- 17 sites in United States, Italy and 1 more
- Volunteers
- 93 people
- Sponsor
- Bristol-Myers Squibb
Muscular Dystrophy, Duchenne
An Open-label Pilot Study of Coenzyme Q10 in Steroid-Treated Duchenne Muscular Dystrophy
This study will help to determine the safety and efficacy of the nutritional supplement Coenzyme Q10 when added to steroids as a treatment for Duchenne muscular dystrophy (DMD).
- Trial name
- NCT00033189
- Testing
- Coenzyme Q10
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Cooperative International Neuromuscular Research Group
Cardiovascular Disease
VIP: Vascular Imaging Project. Study on the Progression of Cardiovascular Disease in Renal Transplant Recipients
This is a prospective randomized study to compare the influence of area under the curve (AUC)-monitored dual treatment with steroids in combination with either a calcineurin inhibitor (CNI) or mycophenolate mofetil (MMF) on the…
- Trial name
- NCT00169910
- Testing
- AUC monitored withdrawal of MMF or CNI
- Where
- Netherlands
- Volunteers
- 119 people
- Sponsor
- Leiden University Medical Center
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