Clinical trials: Stigma, open to volunteers
Major Depressive Disorder (MDD), Gender Differences
Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder
Depression is a common and serious mental health condition that affects mood, thoughts, behavior, and overall quality of life. It arises from a complex interaction of biological, psychological, and environmental factors.
- Conditions
- Major Depressive Disorder (MDD), Gender Differences, Resilience, Psychological, Self Stigma
- Trial name
- GD-GSS-R-S-MDD (NCT07474363)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Eskisehir Osmangazi University
HIV, Cervical Cancer Stigma
RISE: Reducing Cancer and HIV Stigma Through Empowerment
This multilevel randomized behavioral study evaluates participant- and provider-level stigma-reduction interventions in Zambia. Participant-level intervention: Women living with cervical cancer and HIV (WLC+H ) are randomized in…
- Trial name
- NCT07728370
- Testing
- Neutral Video, Storytelling, Self disclosure
- Where
- United States
- Volunteers
- 440 people
- Sponsor
- M.D. Anderson Cancer Center
Depressive Symptoms, Mental Health (Depression)
Using a School-Based Depression Literacy Psychoeducation Program With AI Chatbot to Improve Depression Literacy and Help-Seeking Among High School Students
The primary purpose of this randomized controlled trial is to evaluate the effectiveness of an AI chatbot enhanced school-based depression literacy psychoeducational program, combined with a resource navigation booklet, on high…
- Trial name
- NCT07790731
- Testing
- school-based depression literacy program
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Chang Hsiu-Ju
Stigma, Social, Drug Abuse Illicit
Lower Intersecting HIV-related Stigmas to Facilitate Treatment as Prevention (LIFT)
The purpose of this study is to reduce HIV transmission risk among people who inject drugs (PWID) through a multilevel intervention known as LIFT.
- Conditions
- Stigma, Social, Drug Abuse Illicit, HIV (Human Immunodeficiency Virus)
- Trial name
- LIFT (NCT07541131)
- Testing
- LIFT for People Who Use Drugs, LIFT for MMT Providers
- Where
- Kyrgyzstan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Hypogonadism, Male, Endocrine Disease
Anticipated Stigma, Illness Identity, and Quality of Life in Male Hypogonadism
This study aims to systematically compare the levels of anticipated illness stigma and illness identity among men diagnosed with hypogonadism to those of men with other chronic endocrine conditions (e.g., diabetes mellitus…
- Conditions
- Hypogonadism, Male, Endocrine Disease, Hypertension
- Trial name
- NCT07752511
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Hacettepe University
Schizophrenia Disorder
Reducing Mental Health Stigmatization Among Healthcare Workers and Students Using a Virtual Reality Protocol: The VIRTUS Protocol
Schizophrenia is a chronic psychiatric disorder, frequently associated with stigma, including within healthcare settings, that significantly impairs quality of life and symptoms.
- Trial name
- VIRTUS (NCT07375199)
- Testing
- VIRTUS, VR Control
- Where
- 2 sites in France
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Henri Laborit
Tourette Syndrome, Tic Disorders
Evaluating and Promoting Resilience in Adolescents With Tourette Syndrome
This study adapts and tests PRISM (Promoting Resilience in Stress Management), a short skills-based program that teaches resilience, for teens ages 12-18 with Tourette syndrome or persistent tic disorder.
- Conditions
- Tourette Syndrome, Tic Disorders, Persistent (Chronic) Motor or Vocal Tic Disorder
- Trial name
- PRISM-TS (NCT07905898)
- Testing
- PRISM Intervention, Usual care intervention
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Wake Forest University Health Sciences
HIV, Indonesia
Care Disengagement Prevention in PLWH in Indonesia
This study is being done because the investigators want to learn about how stigma and culture in Indonesia affects how much contact people living with HIV have with the healthcare system and also how it might affect their health…
- Conditions
- HIV, Indonesia, Engagement in HIV Care, Stigma
- Trial name
- NCT07706634
- Testing
- Stigma reduction
- Where
- Indonesia
- Volunteers
- 110 people
- Sponsor
- University of California, Los Angeles
Action Tremor, Stigma, Social
ET Stigma Response to Tremor Suppression
Essential Tremor (ET) is prevalent, affecting approximately 3% of the adult population. Involuntary shaking of the hands during action is a prominent feature, interfering with feeding and writing and other manual tasks.
- Trial name
- NCT07430761
- Testing
- stereotactic thalamotomy with focused ultrasound
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- University of Texas Southwestern Medical Center
Sexual and Gender Minorities, Social Stigma
Examining the Health Effects of NPOWER365 Among Black Same Gender Loving Men
This research study aims to test the effectiveness, reach, and maintenance over time of the NPOWER365 HIV care intervention for Black men who have sex with men (BMSM) living with HIV.
- Conditions
- Sexual and Gender Minorities, Social Stigma, Medication Adherence, Depressive Symptoms
- Trial name
- NCT06315218
- Testing
- NPOWER365 HIV care intervention
- Volunteers
- 350 people
- Sponsor
- Rutgers, The State University of New Jersey
Chronic Disease, Serious Mental Illness
Improving Health and Wellness for People With Serious Mental Illness in Puerto Rico
This study evaluates the effectiveness of a culturally tailored intervention, Bridges to Better Health and Wellness (BRIDGES), aimed at reducing chronic disease disparities among Puerto Ricans with serious mental illness (SMI).
- Trial name
- BRIDGES (NCT06859060)
- Testing
- BRIDGES Healthcare Manager Intervention, Enhanced Treatment as Usual (ETAU)
- Where
- 2 sites in Puerto Rico
- Volunteers
- 300 people
- Sponsor
- Ponce Medical School Foundation, Inc.
Noncommunicable Disease, Psoriasis
Impact of Hand Rub Placement on Patient Trust and Disease Stigma
This study aims to investigate how the physical placement of hand sanitizer in consultation rooms affects patient trust and feelings of disease stigma.
- Trial name
- NCT07552792
- Testing
- Distant placement of hand rub, Conventional placement of hand rub
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Bipolar Disorder, Schizophrenia
COMpassion for Psychiatric Disorders And Self-Stigma
People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into…
- Conditions
- Bipolar Disorder, Schizophrenia, Depression, Borderline Personality Disorder
- Trial name
- COMPASS (NCT05698589)
- Testing
- Compassion Focused Therapy, Ending Self Stigma
- Where
- 7 sites in France
- Volunteers
- 336 people
- Sponsor
- University Hospital, Strasbourg, France
Depression
Efficacy of Narrative Therapy for Older People With Depression
The research aims to investigate the efficacy of a narrative therapy group in reducing depressive symptoms among older people. This study adopts a mixed methods research design, involving both quantitative and qualitative…
- Trial name
- NTOPD (NCT07371988)
- Testing
- Narrative therapy group, Treatment as usual (TAU)
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- City University of Hong Kong
Rectal Cancer, Anal Cancer
Stigma and Psychological profilE in REctal-anal caNcer pAtients
In 2022, Italy is estimated to have 48,100 cases of colon-rectum cancer. Locally advanced mid-lower rectal cancers require preoperative chemo-radiotherapy with fluoropyrimidine.
- Trial name
- SERENA (NCT06366841)
- Testing
- Psychological tests administration
- Where
- 2 sites in Italy
- Volunteers
- 148 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
HIV, Substance Use Disorder (SUD)
Combining Social Network Strategies and Routine Substance Use Screening
This study aims to improve health care for people who may have HIV or substance use disorders by bringing two services to a large community health center in Chicago.
- Trial name
- SNSUS (NCT07414459)
- Testing
- Substance use disorder screening, Social network intervention
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of California, San Diego
Depression - Major Depressive Disorder, HIV
HIV-Mental Illness Stigma Reduction and Outcomes in Malawi
The overall aim of this study is to assess the acceptability, feasibility, fidelity, and effectiveness of a depression treatment intervention augmented with counseling to address stigma.
- Conditions
- Depression - Major Depressive Disorder, HIV, Health Condition Stigma
- Trial name
- NCT06951542
- Testing
- Stigma Reduction Counseling
- Where
- 2 sites in Malawi
- Volunteers
- 200 people
- Sponsor
- University of Pennsylvania
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 163 people
- Sponsor
- University of California, San Francisco
Urinary Tract Infections, Malnutrition
Effect of Hygiene and Menstrual Hygiene Interventions on Learning and Psychosocial Wellbeing in Madagascar
A previous study in schools in rural Madagascar found that a bundle of hygiene-focused interventions substantially improved girls' learning outcomes.
- Conditions
- Urinary Tract Infections, Malnutrition, Inflammation, Stress
- Trial name
- KILONGA2 (NCT07702916)
- Testing
- Peer leadership/sensitization + sanitary pads, School infrastructure
- Where
- Madagascar
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- University of California Santa Cruz
Schizophrenia Disorders
The Effect of Mindfulness-Based Psychoeducation Programme Given Individually to Schizophrenia Patients on Internalised Stigma and Healthy Lifestyle Behaviours
Schizophrenia is a chronic, recurrent and disabling illness that usually lasts a lifetime and causes serious problems in quality of life and functioning.
- Trial name
- NCT06882538
- Testing
- awareness-based psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kastamonu University