Clinical trials: Stillbirths
Delivery Complication, Delivery Problem
Delivery Outcomes by AIDA (Artificial Intelligence Dystocia Algorithm) Analysis
Aims: Primary aim is to investigate outcomes of eutocic labor, evaluating intrapartum ultrasound parameters by AIDA method: Angle of progression (AoP), Asynclitism degree (AD), fetal head-symphysis distance (HSD), and midline…
- Conditions
- Delivery Complication, Delivery Problem, Delivery; Injury, Delivery; Injury, Maternal
- Trial name
- AIDA (NCT06664112)
- Testing
- AIDA Analysis
- Where
- 2 sites in Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Stillbirth, Placental Insufficiency
Placental Risk Assessment to CusTomize Individualized Pregnancy Care and Evaluation
This is a prospective observational study with the goal of developing and assessing a predictive model of placental insufficiency.
- Trial name
- PRACTICE (NCT07144839)
- Testing
- Data Collection Throughout Pregnancy and Delivery
- Where
- United States
- Volunteers
- 640 people
- Sponsor
- Oregon Health and Science University
Stillbirth, Intrauterine Growth Retardation
Antenatal Detection of Fetal Growth Restriction and Stillbirths Rate.
The main objective is to assess the role of antenatal detection of fetal growth restriction (FGR) on stillbirth, by a case-control study in a population-based sample of small for gestational age (SGA) livebirths and stillbirths…
- Conditions
- Stillbirth, Intrauterine Growth Retardation, Infant, Small for Gestational Age
- Trial name
- REPERE (NCT01995968)
- Testing
- Antenatal identification of fetal growth restriction
- Where
- 21 sites in France
- Volunteers
- 480 people
- Sponsor
- University Hospital, Grenoble
Cytomegalovirus Congenital, Hearing Loss
Epidemiology of Congenital Cytomegalovirus in a High HIV Prevalence Setting, South Africa
The aim of this project is to determine the epidemiology of congenital cytomegalovirus (CMV) infection and incidence of subsequent permanent neurological sequelae in a high HIV prevalent setting in Soweto, Johannesburg.
- Conditions
- Cytomegalovirus Congenital, Hearing Loss, Neurodevelopmental Disorders, Immunogenicity
- Trial name
- NCT03722615
- Where
- South Africa
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Witwatersrand, South Africa
Stillbirth and Fetal Death
Intervention to Prevent Mental Health Disorders of Women and Their Partners Who Experienced Pregnancy Loss
The goal of this clinical trial is to test impact of a multiprofessional intervention in mothers and partners who suffer a pregnancy loss.
- Trial name
- Enzo (NCT06340555)
- Testing
- GUIA ATENCION MULTIDISCIPLINAR SANT BOI, USUAL CARE
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació Sant Joan de Déu
Pregnancy, Spontaneous Abortions
Study of the Best Blastocyst Post Transfer by aCGH
An Observational, blind and prospective study of Preimplantational Aneuploidy Screening by aCGH in Trophectoderm Biopsy
- Conditions
- Pregnancy, Spontaneous Abortions, Stillbirth
- Trial name
- NCT01664546
- Testing
- Trophectoderm biopsy
- Where
- Argentina
- Volunteers
- 150 people
- Sponsor
- University of Buenos Aires
Perinatal Death, Hypertension, Pregnancy-Induced
Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution.
- Conditions
- Perinatal Death, Hypertension, Pregnancy-Induced, Abortion, Spontaneous, Stillbirth
- Trial name
- NCT07751432
- Testing
- CC-ANC intervention group.
- Where
- Tanzania
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Caesarean Section;Stillbirth
Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section
This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia.
- Trial name
- NECS (NCT04245891)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Depressive Symptoms, Perinatal Loss
e-Perinatal Butterfly: An Embedded Study for Parents Experiencing Perinatal Loss
This study is part of the e-Perinatal project and is embedded within the parent e-Perinatal cluster randomized controlled trial (NCT07613008). No additional randomization is performed for this embedded study.
- Conditions
- Depressive Symptoms, Perinatal Loss, Perinatal Grief, Anxiety Symptoms
- Trial name
- e-Butterfly (NCT07898176)
- Testing
- e-Perinatal Butterfly, Standard routine maternal care
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Seville
Cholestasis of Pregnancy, Intrahepatic Cholestasis of Pregnancy
Bile Acid Effects in Fetal Arrhythmia Study
Intrahepatic cholestasis of pregnancy (ICP) is a liver disorder of pregnancy that typically presents in late pregnancy with generalised itching.
- Conditions
- Cholestasis of Pregnancy, Intrahepatic Cholestasis of Pregnancy, Obstetric Cholestasis
- Trial name
- BEATS (NCT03519399)
- Testing
- Monica AN24
- Where
- 2 sites in United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stillbirth and Fetal Death, Termination of Pregnancy
A Feasibility Study of Virtopsy With Tissue Sampling in Besancon University Hospital
The aim of this project is to assess the feasibility of a new local post mortem procedure at Besançon University Hospital : Virtopsy+, magnetic resonance (MR) imaging with tissue sampling of the fetus and newborns.
- Conditions
- Stillbirth and Fetal Death, Termination of Pregnancy, Neonatal Death
- Trial name
- VIRTOPSY+ (NCT03877900)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Perinatal Hypoxia
Stillbirth Risk Identification Using Multiparametric Ultrasound
The goal of this observational study is to identify a novel biomarker for stillbirth. Specifically the aim is to predict perinatal hypoxia using quantitative ultrasound from the placenta (QUS-P) between 35 and 37 weeks gestation.
- Trial name
- STIMULUS (NCT06930274)
- Where
- Canada
- Volunteers
- 282 people
- Sponsor
- University of British Columbia
Stillbirth, Post-traumatic Stress Disorder
Feasibility of Online Yoga With Facebook After Stillbirth
The purpose of this study is to investigate the feasibility and effectiveness on PTSD symptoms of the addition of a Facebook group to an online yoga intervention for women following a stillbirth.
- Conditions
- Stillbirth, Post-traumatic Stress Disorder, Anxiety, Depression
- Trial name
- NCT04077476
- Testing
- Online Yoga + Facebook, Online Yoga
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Fetal Growth Retardation, Stillbirth
Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio
To investigate the screening performance of CPR and biophysical profile score for the prediction of composite of adverse neonatal morbidity and mortality and operative delivery (CS or instrumental) for intrapartum fetal distress…
- Conditions
- Fetal Growth Retardation, Stillbirth, Neonatal Respiratory Failure, Neonatal Death
- Trial name
- NCT04640467
- Testing
- Biophsical profile, Cerebroplacental ratio
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Stillbirth
The Tommy's National Rainbow Clinic Study
The death of a baby before or shortly after birth affects approximately 1 in every 250 pregnancies in the UK meaning that over 4,000 parents experience the death of a baby each year in the UK.
- Trial name
- NCT04393259
- Testing
- Rainbow Clinic Model of Antenatal Care
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University of Manchester
Preterm Delivery, Obstetrical Complications
Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial
This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg aspirin or 81 mg aspirin…
- Trial name
- ADEPT (NCT06980025)
- Testing
- 162mg Aspirin, 81mg Aspirin
- Where
- 14 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Stillbirth, Grief
MOMSonLINE2 ; A Pilot Study Testing Recruitment and Retention of Women of Color to an Online Support Group for Bereaved Mothers
This is a 6-week pilot study to see how research participants feel about an internet support site after a stillbirth or infant death. Losing a baby through stillbirth or early infant death is typically devastating for families.
- Conditions
- Stillbirth, Grief, Infant Death
- Trial name
- NCT04600076
- Testing
- BabyCenter site and the community group
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Spontaneous Abortion, Malaria
Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa
Background: In some countries, such as South Africa, the pesticide DDT is an important chemical for control of malaria-carrying mosquitoes. However, there is little evidence about the effects that it might have on human health.
- Conditions
- Spontaneous Abortion, Malaria, Pregnancy Outcome, Stillbirth
- Trial name
- NCT00878098
- Where
- South Africa
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
IUD, Analgesia
TENS Unit for Analgesia During IUD Insertion
Subjects will be screened over the phone or in Tufts GYN clinic for participation in the study. If eligible and interested in participating, written informed consent (and assent if applicable) will be obtained.
- Conditions
- IUD, Analgesia, Patient Preference, Pain, Acute
- Trial name
- NCT06240260
- Testing
- TENS (transcutaneous electrical nerve stimulation) unit, Standard care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tufts Medical Center
Cardiovascular Diseases
Continuation of the nuMoM2b Heart Health Study
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women.
- Trial name
- nuMoM2b-HHS2 (NCT05472597)
- Where
- 14 sites in United States
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- RTI International