Clinical trials: Stimulant Use Disorder
Opioid Use Disorder, Stimulant Use Disorder
Contingency Management for Opioid and Stimulant Use Disorders in Primary Care
Contingency management (CM) is a behavioral intervention that involves incentivizing participants for target behaviors in a clinical setting.
- Trial name
- NCT05288751
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Minnesota
HIV, Stimulant Use Disorder
RESTORE Study R61 Phase: Recovery and Engagement for Stimulant Users on Re-entry
Justice-involved individuals face disproportionately high rates of stimulant use disorder and HIV, along with disrupted access to HIV treatment and prevention services like ART and PrEP.
- Conditions
- HIV, Stimulant Use Disorder, Justice Involved Populations, HIV Prevention
- Trial name
- RESTORE (NCT07136363)
- Testing
- DynamiCare, Patient Navigation (PN)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Cognitive Dysfunction, Stimulant Use
Change in Cognitive Function in Stimulant Users
In Hong Kong, methamphetamine use is common and cocaine use has increased steadily over the past few years. While the use of ketamine decreased from 35.8% in 2015 to 13.9% in 2017, methamphetamine and cocaine have become the most…
- Conditions
- Cognitive Dysfunction, Stimulant Use, Methamphetamine Abuse, Cocaine Use
- Trial name
- SToP-S_CogFx (NCT04061941)
- Testing
- Cognitive Assessment
- Where
- Hong Kong
- Volunteers
- 93 people
- Sponsor
- The University of Hong Kong
Alcohol Abuse, Cannabis Abuse
Study Comparing Two Types of Psychotherapy for Treating Depression and Substance Abuse
The purpose of this study is to determine whether Integrated Cognitive Behavioral Therapy or Twelve Step Facilitation Therapy is most effective for treatment of dually diagnosed veterans with depressive and substance use…
- Conditions
- Alcohol Abuse, Cannabis Abuse, Major Depressive Disorder, Substance-Related Disorders
- Trial name
- NCT00108407
- Testing
- Integrated Cognitive Behavioral Therapy, Twelve Step Facilitation Therapy
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Stimulant Use, Contingency Management
Contingency Management for Stimulant Use Disorders
The invetigators' objective is to implement Medication Assisted Treatment (MAT) and contingency management in patients affected by co-occurring opioid use disorder and stimulant use disorder.
- Trial name
- NCT05097547
- Testing
- Contingency Management
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders
Safety, Tolerability and Abuse Liability Study of Intravenous NRP104 in Adults With Stimulant Abuse Histories
This research is being done to evaluate if NRP 104 is a safe drug. The other purpose is to learn if NRP104, when injected into a vein, produces a high and any other effects like amphetamine and other stimulant drugs that are…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Amphetamine-Related Disorders, Substance-Related Disorders
- Trial name
- NCT00247572
- Testing
- NRP104
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- New River Pharmaceuticals
Anxiety, Depression
An Online Intervention Addressing Mental Health and Substance Use in University Students
The purpose of this study is to assess the effectiveness of mobile app containing a range of evidence based tools to improve the mental health and substance use outcomes of university students.
- Conditions
- Anxiety, Depression, Alcohol Use, Substance Use
- Trial name
- NCT05606601
- Testing
- Minder
- Where
- Canada
- Volunteers
- 1,489 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
HIV, Drug Addiction
Treating South African Pregnant Women for Methamphetamine
The purpose of this study was to develop and initially evaluate an efficacious, comprehensive, culturally sensitive, women-centered model of care for pregnant South African women by adapting and refining PI Jones'…
- Trial name
- NCT01386138
- Testing
- Psycho-education, Experimental
- Where
- South Africa
- Volunteers
- 60 people
- Sponsor
- RTI International
Substance Use Disorder
Functional Connectivity Changes During Early Recovery as a Marker for Relapse
The study purpose is to examine whether there are structural or functional differences in the brains of individuals who use cocaine or amphetamines as opposed to control participants who have never used cocaine or amphetamines.
- Trial name
- NCT02861820
- Testing
- MRI: Brain Imaging Data Collection
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Methamphetamine Use Disorder, Pregnancy
Transcranial Magnetic Stimulation for Methamphetamine Use Disorder During Pregnancy
The goal of this clinical trial is to learn whether transcranial magnetic stimulation, also called TMS, is a practical and acceptable treatment option for methamphetamine use disorder during pregnancy.
- Trial name
- NCT07849530
- Testing
- 4- Week Dual-Target Transcranial Magnetic Stimulation (TMS), Accelerated Dual-Target Transcranial Magnetic Stimulation (aTMS), Treatment as Usual (TAU)
- Volunteers
- 45 people
- Sponsor
- University of Utah
Substance Use Disorders, Alcohol Use Disorder
A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT
Substance Use Disorders continue to increase across the United States with significant adverse effects resulting in more than $700 billion annually (NIDA, 2017) with high co-occurring rates of IPV.
- Conditions
- Substance Use Disorders, Alcohol Use Disorder, Stimulant-Related Disorder
- Trial name
- NCT05943171
- Testing
- Cognitive Behavioral Therapy, Standard CBT
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Methamphetamine Abuse, Methamphetamine-dependence
Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder
Methamphetamine use disorder (MUD) is becoming an increasing public health concern in Canada. While the evidence on the efficacy and safety of prescription psychostimulants for the treatment of MUD is promising, the knowledge on…
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance Abuse
- Trial name
- NCT06788587
- Testing
- LDX-01 plus TAU
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Attention Deficit Hyperactivity Disorder, Stimulant Use
Acute Effects of Stimulant Medication in College Students With ADHD
The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent…
- Conditions
- Attention Deficit Hyperactivity Disorder, Stimulant Use, Working Memory, Change in Sustained Attention
- Trial name
- NCT03935646
- Testing
- Adderall IR 10mg
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Cocaine Dependence, Substance Use Disorders
Transcranial Magnetic Stimulation for Cocaine Addiction
Background: Cocaine use disorders (CUD) is a complex brain disorder, involving several brain areas and neurocircuits. Effective treatments for CUD are still needed.
- Conditions
- Cocaine Dependence, Substance Use Disorders, Chemical Addiction, Mental Disorder
- Trial name
- BRAINSWITCH (NCT03333460)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Stimulant Use, Stimulant-Related Disorder
The Longitudinal Study of Stimulant Use Disorder
This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation.
- Conditions
- Stimulant Use, Stimulant-Related Disorder, Healthy
- Trial name
- STIM-RAD (NCT06073340)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Stimulant Use Disorder, Cocaine Use Disorder
LDART for Stimulant Use Disorder
The goal of this study is to evaluate the feasibility, acceptability, and preliminary efficacy of a digital intervention called LDART in adults with stimulant use disorder.
- Conditions
- Stimulant Use Disorder, Cocaine Use Disorder, Methamphetamine Use Disorder
- Trial name
- LDART (NCT07221396)
- Testing
- LDART, Psychoeducational booklet
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Human Immunodeficiency Virus
HIV and Drug Use in Georgian Women
The purpose of this study is to determine how drug abuse treatment interventions can be integrated with established Human Immunodeficiency Virus prevention approaches to optimize their combined effectiveness.
- Trial name
- IMEDI (NCT01331460)
- Testing
- RBT, Case-Management
- Where
- Georgia
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Methamphetamine Abuse, Substance Use Disorders
rTMS for Craving in Methamphetamine Use Disorder
The primary aim of this project is to use a randomized single-blind sham-controlled study to investigate if high frequency repetitive transmagnetic stimulation (HF-rTMS) can modulate cue-induced craving in adult methamphetamine…
- Conditions
- Methamphetamine Abuse, Substance Use Disorders, Stimulant Dependence, Methamphetamine-dependence
- Trial name
- NCT03470480
- Testing
- Real Repetitive transcranial magnetic stimulation, Methamphetamine visual cues, Neutral visual cues
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Oregon Health and Science University
Opioid Use, Stimulant Use
Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City
The sequential trial compares recovery and mHealth engagement outcomes among Black participants who participated in the mHealth intervention uMAT-R or uMAT-R + enhanced community engagement.
- Conditions
- Opioid Use, Stimulant Use, Depression and Anxiety Symptoms
- Trial name
- NCT07673380
- Testing
- uMAT-R + enhanced community engagement, Original uMAT-R supplementary mHealth recovery intervention
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Washington University School of Medicine
Amphetamine Use Disorders
Transcranial Magnetic Stimulation for Treatment of Methamphetamine Use Disorder
Repetitive transcranial magnetic stimulation (rTMS) was used to treat methamphetamine use disorder in previous studies, while the evidence-based protocols still required.
- Trial name
- NCT03736317
- Testing
- real mPFC cTBS, real dlPFC iTBS, real dlPFC iTBS + real mPFC cTBS
- Where
- China
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center