Clinical trials: Stomach Diseases
Pancreatic Ductal Adenocarcinoma, Colorectal Cancer
Study to Evaluate the Safety and Activity (Including Distribution) of 177Lu-3BP-227 in Subjects With Solid Tumours Expressing Neurotensin Receptor Type 1.
This study was conducted to advance new treatment for patients with metastatic or locally advanced cancers expressing Neurotensin receptor 1 (NTSR1).
- Conditions
- Pancreatic Ductal Adenocarcinoma, Colorectal Cancer, Gastric Cancer, Squamous Cell Carcinoma of the Head and Neck
- Trial name
- NCT03525392
- Testing
- 177Lu-3BP-227 (also called 177Lu-IPN01087)
- Where
- 8 sites in United States, Belgium and 3 more
- Volunteers
- 14 people
- Sponsor
- Ipsen
Gastric Cancer
A Study of Cetuximab(Erbitux) With Cisplatin and Capecitabine(Xeloda)as 1st Line Treatment in the Advanced Gastric Cancer
The purpose of this study is to investigate whether cetuximab (Erbitux®) with cisplatin and capecitabine (Xeloda) as 1st line treatment in the advanced gastric cancer is effective.
- Trial name
- EXTRA (NCT00477711)
- Testing
- cetuximab, cisplatin, capecitabine
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Peking University
Gastric Cancer, RWS
A Real-world Study of Camrelizumab Alone or in Combination With Apatinib/Chemotherapy for Advanced Gastric Cancer
The purpose of this observational study is to evaluate the safety and efficacy of camrelizumab and apatinib in patients with advanced gastric cancer under real-life conditions, particularly in various subgroups of gastric cancer…
- Conditions
- Gastric Cancer, RWS, PD-1 Immunotherapy
- Trial name
- NCT06485271
- Testing
- Camrelizumab, apatinib, chemotherapy
- Where
- China
- Volunteers
- 504 people
- Sponsor
- Changzhi People's Hospital Affiliated to Changzhi Medical College
Gastric Ulcer
Efficacy of TAK-438 Compared to AG-1749 (Lansoprazole) in the Treatment of Gastric Ulcer
The purpose of this study is to investigate the efficacy of TAK-438, once daily (QD), compared to lansoprazole in patients with gastric ulcer.
- Trial name
- NCT01452711
- Testing
- TAK-438, Lansoprazole
- Where
- 64 sites in Japan
- Volunteers
- 482 people
- Sponsor
- Takeda
Advanced Solid Tumors
A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors
This is a first-in-human, Phase 1/2 study to evaluate LCB84, a TROP2-directed antibody-drug conjugate, alone and in combination with an anti-PD-1 Ab, in dose escalation (Phase 1) followed by dose expansion (Phase 2).
- Trial name
- NCT05941507
- Testing
- LCB84, Anti-PD-1 monoclonal antibody
- Where
- 8 sites in United States, Canada
- Volunteers
- 300 people
- Sponsor
- LigaChem Biosciences, Inc.
Gastric Cancer
Immunomodulating Nutrients in Perioperative Patients With Gastric Cancer
The survey is a phase IV, prospective randomized clinical trial to determine whether an immunomodulating nutrient-enriched diet compared to a standard diet can improve nutritional status and reduce postoperative infection and…
- Trial name
- NCT03123432
- Testing
- immunomodulating nutrients enriched diet, standard diet
- Where
- Taiwan
- Volunteers
- 34 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Non-small Cell Lung Cancer, Esophageal Cancer
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery.
- Conditions
- Non-small Cell Lung Cancer, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT02838836
- Testing
- Study sample collection
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Gastric Cancer, Nutrition
Evaluation of Four Reconstructions After Total Gastrectomy
There are four capital reconstructions after total gastrectomy which is widely used in China. Life quality is the only standard to evaluate postoperative results of different reconstructions.
- Trial name
- NCT00677456
- Testing
- R-Y reconstruction after total gastrectomy, P-Y reconstruction after total gastrectomy, Pouch reconstruction after total gastrectomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tang-Du Hospital
Gastric Cancer, Gastric Metaplasia
Narrow Band Imaging for Gastric Neoplasia
It is thought that the development of cancer of the stomach follows a series of stages in which the lining becomes increasingly abnormal. Early detection of precursors of gastric cancer likely enable less invasive treatment.
- Conditions
- Gastric Cancer, Gastric Metaplasia, Gastric Dysplasia
- Trial name
- NCT02197351
- Testing
- White light biopsy, Protocolled, Narrow Band Imaging Guided Biopsy
- Where
- 2 sites in United States, Portugal
- Volunteers
- 220 people
- Sponsor
- University of Southern California
Stomach Neoplasms
Prospective Study on Modified Delta-shaped Gastroduodenostomy in Totally Laparoscopic Surgery for Distal Gastric Cancer
The purpose of this study is to explore the clinical application value of modified delta-shaped gastroduodenostomy in totally laparoscopic surgery for distal gastric cancer.
- Trial name
- MDSG (NCT02289183)
- Testing
- Totally laparoscopic distal gastrectomy, Laparoscopy-assisted distal gastrectomy
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Fujian Medical University
Chagas' Disease (Chronic) Nos
Oral Fexinidazole Dosing Regimens for the Treatment of Adults With Chronic Indeterminate Chagas Disease
This study focuses on the evaluation of low doses (600 and 1200 mg) and short treatment duration (at 3, 7 and 10 days) of fexinidazole (Fexi) to determine the minimal efficacious and safe dose for the treatment of adult patients…
- Trial name
- FEXI12 (NCT03587766)
- Testing
- Fexinidazole
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Drugs for Neglected Diseases
Oesophageal Cancer, Gastric Cancer
Modulated Mid-frequency Whole-body Electromyostimulation and Nutritional Therapy in Gastrointestinal Cancer Patients
The purpose of this study is to assess the efficacy of modulated mid-frequency whole-body electromyostimulation (WB-EMS) combined with nutritional therapy in patients with gastrointestinal cancer.
- Conditions
- Oesophageal Cancer, Gastric Cancer, Duodenal Cancer, Colorectal Cancer
- Trial name
- MOMENT (NCT06414122)
- Testing
- mid-frequency whole-body electromyostimulation (WB-EMS), conventional exercise training, nutritional therapy
- Where
- Germany
- Volunteers
- 88 people
- Sponsor
- University of Cologne
Obesity
Use of Radiofrequency Ablation for RGB Salvage
The present study will assess the feasibility of using endoscopic radiofrequency ablation (RFA) to treat the gastric pouch and stoma with the intent to cause tissue contraction and decreased compliance after a failed Roux-en-Y…
- Trial name
- NCT01910688
- Testing
- RFA treatment
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Esophageal Dysfunction, Pylorus Dysfunction
Normal Values for Esophageal and Pyloric Impedance Planimetry Under General Anesthesia (NormaFLIP)
Impedance planimetry using Endoscopic Functional Lumen Imaging Probe (EndoFLIP) device is a promising diagnostic tool to assess esophageal, esophago-gastric junction and pylorus function.
- Trial name
- NormaFLIP (NCT02905669)
- Testing
- EndoFLIP
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Gastric Cancer
Enriched-CRT 2017: Advanced Gastric Cancer With LN+ and LVI+, Chemotherapy vs. Chemoradiotherapy
This Enriched-CRT 2017 trial is a prospective, multicenter trial for adjuvant chemoradiotherapy (CRT) and chemotherapy (CT) in radical resected advanced gastric cancer (GC) patients with lymph node metastasis (LN+) and…
- Trial name
- NCT03680261
- Testing
- chemoradiotherapy, chemotherapy
- Where
- China
- Volunteers
- 556 people
- Sponsor
- Shanghai Zhongshan Hospital
Advanced Gastric Cancer
Capecitabine and Cisplatin (XP)+Sorafenib in Advanced Gastric Cancer (AGC): Sorafenib+XP
There is strong scientific rationale for exploring the role of sorafenib with capecitabine and cisplatin (XP) in AGC. XP is a new standard of care in AGC and sorafenib is a novel signal transduction inhibitor that prevents tumor…
- Trial name
- NCT00565370
- Testing
- Capecitabine, Cisplatin, Sorafenib
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Asan Medical Center
Microbial Colonization, Preterm Birth
Gastric Bacterial Colonization of Preterm Neonates
This prospective cohort study was conducted in the Christiana Care Health System Neonatal Intensive Care Unit. It occurred at two time periods: Time period 1 included infants admitted to the traditional, open bay NICU.
- Trial name
- NCT05385939
- Testing
- Observational
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Obesity, Weight Loss
Bariatric Embolization Trial for the Obese Nonsurgical
The purpose of this study is to assess the safety profile of bariatric embolizations and confirm published reports of sustained post-procedural weight loss, and pathologically assess post-procedural metabolic effects.
- Conditions
- Obesity, Weight Loss, Body Weight, Morbid Obesity
- Trial name
- BET-ON (NCT03601273)
- Testing
- Left gastric artery embolization
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity, Morbid Obesity
Study of Weight Loss Using Gastric Stimulation in Obese Patients
The purpose of this study is to test the effect of an implanted device that stimulates the stomach to help obese patients lose weight.
- Trial name
- SHAPE (NCT00200083)
- Testing
- Transcend II Model 8848
- Where
- 8 sites in United States
- Volunteers
- 190 people
- Sponsor
- MedtronicNeuro
Breast Neoplasms, Stomach Neoplasms
A Dose-escalation Study of ARX788, IV Administered in Subjects With Advanced Cancers With HER2 Expression
This is a 2-part, Phase 1 FIH study with Phase 1a designed to determine the maximum tolerated dose (MTD)/recommended Phase 2 dose (RP2D) in subjects with metastatic cancers with a human epidermal growth factor receptor 2 (HER2)…
- Trial name
- NCT02512237
- Testing
- ARX788
- Where
- 7 sites in Australia, New Zealand
- Volunteers
- 9 people
- Sponsor
- Zhejiang Medicine Co., Ltd.
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