Clinical trials: Stomach Diseases
Stomach Neoplasms, Robotic Surgical Procedures
Single-port Versus Conventional Laparoscopic Surgery for Radical Proximal Gastric Cancer: A Randomized Controlled Trial
To evaluate the safety and efficacy of SP1000 and conventional laparoscopy in radical gastrectomy for proximal gastric cancer.
- Trial name
- NCT07586384
- Testing
- Single-Port Robotic Surgical System, Traditional Laparoscopic Surgery
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Wenzhou Medical University
Hematopoietic Stem Cell Transplantation (HSCT), aGVHD
GMPA Versus PPI for Gastric Protection and aGVHD Risk
The goal of this clinical trial is to observe whether different gastric protection strategies affect the incidence of acute graft-versus-host disease (aGVHD) in patients undergoing allogeneic hematopoietic stem cell…
- Conditions
- Hematopoietic Stem Cell Transplantation (HSCT), aGVHD, Infection, Mortality
- Trial name
- NCT07791849
- Testing
- Teprenone, Esomeprazole
- Where
- China
- Volunteers
- 198 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Gastric Cancer
A Clinical Study of Adebrelimab Combined With Apatinib and Paclitaxel in Patients With Advanced Gastric Cancer.
Phase II Clinical Study of Adebrelimab Combined with Apatinib and Paclitaxel for Injection(Albumin Bound) as Second-line Therapy in Patients with Advanced Gastric Cancer Previously Treated with Immunotherapy
- Trial name
- NCT06339216
- Testing
- Adebrelimab+Apatinib+Paclitaxel for Injection(Albumin Bound)
- Volunteers
- 30 people
- Sponsor
- Chinese PLA General Hospital
Coronary Artery Disease, Left Ventricular Systolic Dysfunction
Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass Surgery
This study aims to investigate whether reduced heart function is associated with differences in stomach contents before elective coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Left Ventricular Systolic Dysfunction, Gastric Contents
- Trial name
- NCT07898215
- Testing
- Gastric Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University
Obesity
Microenvironment of Adipose Tissue in Endocannabinoid System
The purpose of this study is examine the relationship between adipose tissue inflammation and activation of the endocannabinoid system before and after Roux-en-Y gastric bypass surgery.
- Trial name
- NCT00978289
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University
Ulcers, Gastric
Efficacy and Safety of Vonorasan Versus Esomeprazole in the Treatment of Ulcers After Endoscopic Submucosal Dissection
The purpose of this clinical trial is to find out the effectiveness of voronasan in combination with aluminum phosphate gel in the treatment of post-operative ESD ulcers.
- Trial name
- NCT06526455
- Testing
- Vonoprazan, Esomeprazole
- Where
- 5 sites in China
- Volunteers
- 196 people
- Sponsor
- Shicai Ye
Stomach Neoplasms
Phase 3 Study of Xelox Followed by Maintenance Capecitabine in the Advanced Gastric Cancer
XELOX regimen had a more favorable toxicity profile compared to cisplatin for patients with advanced gastric cancer. The safety profile of oxaliplatin makes it an ideal candidate for combination therapy.
- Trial name
- NCT02289547
- Testing
- Capecitabine
- Where
- 8 sites in South Korea
- Volunteers
- 184 people
- Sponsor
- The Catholic University of Korea
Gastric Disease
A Study to Evaluate Endoscopic Visibility of Stomach After a Combination Drink of N-acetylcysteine and Simethicone
Endoscopy is the diagnostic modality for most gastroduodenal diseases. During endoscopy mucus and foam may actually interfere with the visibility of the stomach mucosa.
- Trial name
- NCT05801055
- Testing
- Evaluation of gastric visibility following the combination drink of N-acetyle cysteine and simethocone
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Gastric Cancer
Questionnaire Survey of the Advanced Training Program for Laparoscopic Radical Gastrectomy
This study aims to evaluate the outcomes of the advanced training program for laparoscopic radical gastrectomy (ATP-LRG). The research subjects are the trainees who participated in this training program.
- Trial name
- ATP-LRG-1 (NCT05219539)
- Where
- China
- Volunteers
- 1,355 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Insomnia
A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia
This is a multi center, double blind placebo controlled, two-way crossover study in patients with Insomnia suffering from difficulty in falling asleep and staying asleep.
- Trial name
- NCT01277107
- Testing
- Zaleplon AP formulation
- Where
- 6 sites in United States, Israel
- Volunteers
- 83 people
- Sponsor
- Intec Pharma Ltd.
Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck
A Study of Sigvotatug Vedotin in Advanced Solid Tumors
This trial will look at a drug called sigvotatug vedotin (SGN-B6A) alone and with pembrolizumab, with or without chemotherapy, to find out whether it is safe for people who have solid tumors.
- Conditions
- Carcinoma, Non-Small Cell Lung, Squamous Cell Carcinoma of Head and Neck, HER2 Negative Breast Neoplasms, Esophageal Squamous Cell Carcinoma
- Trial name
- NCT04389632
- Testing
- sigvotatug vedotin, pembrolizumab, cisplatin
- Where
- 158 sites in United States, France and 5 more
- Volunteers
- 1,006 people
- Sponsor
- Seagen, a wholly owned subsidiary of Pfizer
Gastroparesis
Dose Response of 28 Days of Dosing of GSK962040 in Type I and II Diabetic Male and Female Subjects With Gastroparesis
GSK962040 is a novel small molecule motilin agonist. The Phase I studies (MOT107043 and MOT109681) demonstrated that single doses of GSK962040 up to 150 mg and repeat dosing of up to 125 mg/day for 14 days were well tolerated…
- Trial name
- NCT01262898
- Testing
- GSK962040 (5 mg tablet), GSK962040 (25 mg tablet), GSK962040 (125 mg tablet)
- Where
- 22 sites in United States, Australia and 4 more
- Volunteers
- 79 people
- Sponsor
- GlaxoSmithKline
Gastric Ulcers, Duodenal Ulcers
Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin
The purpose of this study is to evaluate the efficacy of TAK-438, once daily (QD) compared to AG-1749 (Lansoprazole) in patients with a history of gastric or duodenal ulcer who require long-term therapy of low-dose aspirin.
- Trial name
- NCT01452763
- Testing
- TAK-438, Lansoprazole
- Where
- 76 sites in Japan
- Volunteers
- 621 people
- Sponsor
- Takeda
Adults,Gastric Symptoms,Suspected Gastric Motility Disorders
Non-invasive Measurement of Gastric Motility
Clinical evaluation to compare performance of the physiological recordings from the Gastric Alimetry System vs a predicate reference device (Medtronic Polygram NET / Polygraf ID EGG System
- Trial name
- NCT04992884
- Testing
- Gastric Alimetry
- Where
- New Zealand
- Volunteers
- 25 people
- Sponsor
- Greg O'Grady
Cancer, All Types, Cancer of Liver
The PIONEER Initiative: Precision Insights On N-of-1 Ex Vivo Effectiveness Research Based on Individual Tumor Ownership (Precision Oncology)
The PIONEER Initiative stands for Precision Insights On N-of-1 Ex vivo Effectiveness Research. The PIONEER Initiative is designed to provide access to functional precision medicine to any cancer patient with any tumor at any…
- Conditions
- Cancer, All Types, Cancer of Liver, Cancer of Stomach, Cancer of Head and Neck
- Trial name
- PIONEER (NCT03896958)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- SpeciCare
Gastric Cancer
A Study of Ramucirumab in Treating Japanese Participants With Metastatic Gastric or Gastroesophageal Junction Cancer
The purpose of this study is to evaluate progression-free survival in participants with gastric or gastroesophageal junction cancer who have had disease progression following first-line therapy who undergo treatment with…
- Trial name
- NCT01983878
- Testing
- Ramucirumab
- Where
- 11 sites in Japan
- Volunteers
- 36 people
- Sponsor
- Eli Lilly and Company
Duodenal Ulcer
Ilaprazole for the Treatment of Duodenal Ulcer in Chinese Patients (Phase 3)
Patients with endoscopically diagnosed active duodenal ulcer disease were enrolled in a randomized, double-blind, parallel and positive-controlled trial.
- Trial name
- NCT00952978
- Testing
- 10 mg ilaprazole, 20 mg omeprazole
- Where
- China
- Volunteers
- 496 people
- Sponsor
- Livzon Pharmaceutical Group Inc.
Early Gastric Cancer, Barrett Esophagus
Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer Precursors
This study aims to examine the use of Linked Color Imaging in detection of gastric cancer precursors, as well as oesophageal and duodenal lesions.
- Trial name
- NCT03990025
- Testing
- Linked Color Imaging, White Light Imaging
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- Changi General Hospital
Esophageal Neoplasms
Home Jejunostomy Feeding Following Esophagectomy/Gastrectomy
After surgery for oesophageal (gullet) or gastric (stomach) cancer, patients are routinely fed by means of a small feeding tube into the intestine (jejunostomy, JEJ) while they are in hospital.
- Trial name
- NCT01870817
- Testing
- Home jejunostomy feeding
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- University Hospitals, Leicester
Stomach Cancer
Development of a Versatile Intra-operative On-screen Audiovisual Mentoring System Using TileproTM Program for Robotic Gastrectomy
Considering the development of gastric cancer surgery using da Vinci Robotic Surgical System, the development of educational program needs to be achieved in Korea and this institute.
- Trial name
- NCT01319084
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
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