Clinical trials: Stomach Diseases
Cancer-related Fatigue, Breast Cancer
Guaraná Supplementation for Cancer-Related Fatigue
Cancer-related fatigue is one of the most common and distressing symptoms experienced by patients during and after cancer treatment, and current options to manage it are limited.
- Conditions
- Cancer-related Fatigue, Breast Cancer, Lung Cancer, Colorectal Cancer
- Trial name
- GUARANA-CRF (NCT07816263)
- Testing
- Guaraná (Paullinia cupana)
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo
Gastroesophageal Reflux Disease, Depression
Zuojin Wan Combined With Woonosan Fumarate for the Treatment of GRD Combined With Depression
To evaluate the improvement of symptoms in patients with gastroesophageal reflux disease combined with depression (hepatic and gastric depression-heat type) by Zuojin Wan combined with vornodine fumarate regimen as a control, and…
- Trial name
- NCT06481787
- Testing
- Vonorasan Fumarate, Zuojin Pills
- Volunteers
- 300 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Gastro-Intestinal Disorder
Ionizing Radiation During Endoscopic Procedures (ENDORAY Study)
The primary objective of this prospective study was to describe the evolution of dose reference levels (DRLs) in a specialized French center during endoscopic procedures involving ionizing radiation and performed without a…
- Trial name
- ENDORAY (NCT07009587)
- Testing
- Endoscopy
- Where
- France
- Volunteers
- 2,782 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Gastric Cancer (Diagnosis)
Screening and Validation of Serum Protein Biomarkers for Early Diagnosis of Gastric Cancer
This study focuses on the discovery of protein biomarkers for the early diagnosis of gastric cancer and the development of corresponding detection methods.
- Trial name
- NCT07096752
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Gastric Carcinoma
XELOX Combined With Apatinib as Post-operative Chemotherapy in Locally Advanced Gastric Adenocarcinoma
To observe and evaluate the efficacy and safety of oxaliplatin with oapecitabine（XELOX）combined with apatinib as post-operative chemotherapy in locally advanced gastric adenocarcinoma with D2 dissection
- Trial name
- NCT03599778
- Testing
- Apatinib
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Anhui Provincial Hospital
Pancreatic Cancer, Small Bowel Cancer
Expanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered Malignancies
The objective of this expanded access program is to provide ulixertinib (BVD-523) for compassionate use in advanced cancer patients with MAPK pathway-altered solid tumor(s), including but not limited to KRAS, NRAS, HRAS, BRAF…
- Conditions
- Pancreatic Cancer, Small Bowel Cancer, Colorectal Cancer, Melanoma
- Trial name
- NCT04566393
- Testing
- Ulixertinib (BVD-523)
- Where
- 26 sites in United States
- Sponsor
- xCures
Obesity, Hormone Responses
Effect of Gastric Bypass Surgery on Brain Responses
After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (~ 2 years).
- Conditions
- Obesity, Hormone Responses, Cognitive Health
- Trial name
- NCT01815216
- Testing
- Bariatric surgery, Brain activity in resting state, Memory performance
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Uppsala University
Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass
Laparoscopic Revision of Jejunoileal Bypass to Gastric Bypass
This study objectives are the following. To describe the updated clinical presentation, indications, and multidisciplinary medical management of patients with a failed and/or complicated jejunoileal bypass (JIB).
- Conditions
- Clinically Severe Obesity, Metabolic Complications After Jejunoileal Bypass, Nutritional Complications After Jejunoileal Bypass, Obesity Recidivism
- Trial name
- JIB-to-RYGB (NCT01040533)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Francisco
Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction
Erlotinib Hydrochloride in Treating Patients With Advanced Esophageal Cancer or Stomach Cancer
This phase II trial is studying erlotinib hydrochloride to see how well it works in treating patients with advanced esophageal cancer or stomach cancer.
- Conditions
- Adenocarcinoma of the Esophagus, Adenocarcinoma of the Gastroesophageal Junction, Recurrent Esophageal Cancer, Squamous Cell Carcinoma of the Esophagus
- Trial name
- NCT00045526
- Testing
- erlotinib hydrochloride, laboratory biomarker analysis
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Cancer Institute (NCI)
Obesity, Endoscopic Sleeve Gastroplasty
Endoscopic Sleeve Gastroplasty for Obesity and Microbiota Randomized Trial
This is an interventional, open-label, randomized (2:1), standard medical therapy-controlled trial. Subjects in the standard therapy group will be given the opportunity to undergo the active endoscopic treatment after 6 months of…
- Conditions
- Obesity, Endoscopic Sleeve Gastroplasty, Gastric Motility, Gastric Hormones
- Trial name
- ESGORT (NCT04200144)
- Testing
- Endoscopic sleeve gastroplasty
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Abdominal Pain
Chronic Abdominal Pain After Gastric Bypass
The study aims to explore patients perception of chronic abdominal pain after Roux en Y gastric bypass surgery for morbid obesity. The investigators aim to describe characteristics of symptoms of pain.
- Trial name
- NCT03455998
- Testing
- questionnaires
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hyperglycemia, Insulin Sensitivity
Investigating Inter-individual Variability in Glycemic and Insulin Responses
This study aims to test the following hypothesis in healthy lean young men: There are differences in glycemic response (GR) and insulin response (IR) between Chinese, Malay and Asian-Indian There are differences in GI values to…
- Trial name
- NCT01804738
- Testing
- Jasmine rice, Parboiled basmati rice
- Where
- Singapore
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Bariatric Surgery (Gastric Bypass), Severe Obesity
Gut Hormones as Mediators of Different Weight Loss Responses After Roux-en-Y Gastric Bypass
After gastric bypass, 10-20% of patients will obtain a suboptimal weight loss, often defined as <50% of the excess body weight. Exaggerated meal related secretion of gut hormones seem important for appetite reduction and…
- Trial name
- NCT02374632
- Testing
- Meal tests after saline injection, Meal tests after octreotide injection
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital
Gastrointestinal Cancer, Cholangiocarcinoma
Treatment of Cabotamig (ARB202) in Advanced Gastrointestinal Cancer Patients
This study aims to find out: 1. The tolerability of Cabotamig (ARB202) in adults with advanced solid gastrointestinal tumors who failed the standard treatment. People can participate if their tumor has the CDH17 marker. 2.
- Conditions
- Gastrointestinal Cancer, Cholangiocarcinoma, Liver Cancer, Colorectal Adenocarcinoma
- Trial name
- NCT05411133
- Testing
- Cabotamig (ARB202)
- Where
- 3 sites in Australia, Hong Kong
- Volunteers
- 33 people
- Sponsor
- Arbele Pty Ltd
Gastric Adenocarcinoma, Gastric Cancer
A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer
This study will assess the efficacy, safety, optimal dose and ADA and NAbs development of TRK-950 at two separate dose levels in combination with ramucirumab and paclitaxel (RAM+PTX) as compared with RAM + PTX treatment alone in…
- Conditions
- Gastric Adenocarcinoma, Gastric Cancer, Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT06038578
- Testing
- TRK-950, Ramucirumab, Paclitaxel
- Where
- 27 sites in United States, Japan and 1 more
- Volunteers
- 146 people
- Sponsor
- Toray Industries, Inc
Gastric Cancer
Adebrelimab and Fruquintinib Combined With Paclitaxel/Albumin Paclitaxel for Advanced Gastric Cancer
This is a prospective, single-center, open, single-arm clinical study to observe and evaluate the efficacy and safety of Fruquintinib and Adebrelimab combined with paclitaxel/albumin paclitaxel for second-line treatment of…
- Trial name
- NCT06102772
- Testing
- Adebrelimab，Fruquintinib
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Stomach Neoplasms
ctDNA for Prediction of Relapse in Gastric Cancer
Gastric cancer is one of the common malignant tumors in China, with relatively high incident rate and mortality among the population.
- Trial name
- NCT02887612
- Testing
- ctDNA test
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Pancreatic Cancer, Colon Cancer
Cancer Loyalty Card Study 2 (CLOCS-2)
Cancer is one of the leading causes of mortality worldwide and is responsible for an estimated 9.6 million deaths yearly. Cancer-related deaths can be reduced if patients are diagnosed and treated early.
- Conditions
- Pancreatic Cancer, Colon Cancer, Oesophageal Cancer, Stomach Cancer
- Trial name
- (CLOCS-2) (NCT06447064)
- Testing
- Cases & Controls
- Where
- United Kingdom
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stomach Cancer, Gastric Cancer
Neoadjuvant Chemotherapy With PISOXO for Locally-invaded-gastric Cancer (LIGC)
The main purpose of this study is to compare the safety and efficacy of PIPAC+SOX+OLAPARIB for locally-invaded-gastric cancer (LIGC) patients in China.
- Trial name
- NCT04410887
- Testing
- PIPAC+SOX+OLAPARIB
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Ruijin Hospital
Aspiration Pneumonia
Gastric POCUS for Airway Management in Patients Using Glucagon-like Peptide-1 Receptor Agonist (Multicentric)
1. Introduction Scheduled surgery requires patients to undergo a preoperative fasting period of at least 6 hours to reduce the risk of perioperative pulmonary aspiration.
- Trial name
- POCUS (NCT06666049)
- Testing
- Gastric Ultrasound
- Where
- 2 sites in Spain
- Volunteers
- 39 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
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