Clinical trials: Stomach Diseases
Obesity, Gastroesophageal Reflux
Ultrasound Assessment for Comparison of Gastric Residual Volume After Ingestion of Carbohydrate Drink and Water in Obesity Class II and III Volunteers at Risk of Aspiration
The goal of this clinical trial is to compare gastric residual volume between drinking a carbohydrate drink and water in obesity class II and III volunteers at risk of aspiration.
- Trial name
- CarbDrinkUltra (NCT06941623)
- Testing
- Ultrasonography of gastric residual volume, Point-of-care testing of glucose, Hunger numeric rating scale
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Severe Obesity
Influence of Gut Hormones on Food Intake After Roux-en-Y Gastric Bypass Surgery
The aim of this study is to examine the effect of GLP-1 and other gut-secreted hormones (glucagon, GIP, grelin and PYY) on food-intake, appetite and glucose metabolism after Roux-en-Y gastric bypass surgery.
- Trial name
- NCT02336659
- Testing
- exendin 9-39, sitagliptin
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Hvidovre University Hospital
Gastric Cancer
Real World Study of Immune Checkpoint Inhibitors for Advanced Gastric Cancer
Gastric cancer ranks as the fifth most common and the third most common cause of cancer deaths in the world. In spite of the progresses made in the diagnosis and treatment of gastric cancer in the past decades, the prognosis is…
- Trial name
- NCT04086888
- Where
- 2 sites in China
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Stomach Neoplasm
Laparoscopic vs. Open Distal Gastrectomy After Neoadjuvant Chemotherapy
The study was designed as single-country, multi-center, open-labelled, randomized (1:1), phase II trial. 238 patients with medically and technically operable advanced gastric adenocarcinoma in middle or distal 1/3 of stomach are…
- Trial name
- NCT04658589
- Testing
- Laparoscopic versus open distal gastrectomy
- Volunteers
- 238 people
- Sponsor
- Chonnam National University Hospital
Oncology, Melanoma
Glycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)
This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.
- Conditions
- Oncology, Melanoma, Ovarian Cancer, NSCLC
- Trial name
- GLIMMER-01 (NCT05259696)
- Testing
- E-602, Cemiplimab
- Where
- 13 sites in United States
- Volunteers
- 69 people
- Sponsor
- Palleon Pharmaceuticals, Inc.
Gastroenteritis, Rota Virus Gastroenteritis
Admission Pattern Among Children With Gastro-intestinal Infections Before and During the Covid-19 Pandemic
During the Covid-19 pandemic, admission patterns for infections other than Covid-19 have changed dramatically among children worldwide.
- Conditions
- Gastroenteritis, Rota Virus Gastroenteritis, Dehydration in Children, Infectious Disease
- Trial name
- NCT06211621
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Region Zealand
Obesity, Hormone Responses
Effect of Gastric Bypass Surgery on Brain Responses
After obesity surgery gastric bypass (GBP) patients usually lose more than 50% of its former preponderance in relative short time (~ 2 years).
- Conditions
- Obesity, Hormone Responses, Cognitive Health
- Trial name
- NCT01815216
- Testing
- Bariatric surgery, Brain activity in resting state, Memory performance
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Uppsala University
Uncut Roux-en-Y, Roux-en-Y
Uncut Roux-en-Y vs Roux-en-Y
Uncut Roux-en-Y vs Roux-en-Y reconstruction after distal gastrectomy for gastric cancer
- Conditions
- Uncut Roux-en-Y, Roux-en-Y, Gastric Cancer
- Trial name
- NCT03349398
- Testing
- Uncut Roux-en-Y reconstruction, Roux-en-Y reconstruction
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Jilin University
Gastric Cancer
Gastric Cancer Marker Detection and Its Kit Development
The gastric cancer diagnosis and treatment specifications clearly point out that tumor markers need to be detected in the process of diagnosis, efficacy evaluation and follow-up.
- Trial name
- GCMDKD (NCT05010863)
- Testing
- Blood collection
- Where
- China
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Gastric Adenocarcinoma
Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma
The purpose of this study was to evaluate the efficacy of derazantinib monotherapy or derazantinib in combination with paclitaxel and ramucirumab in patients with gastric adenocarcinoma (GAC) i.e.
- Trial name
- FIDES-03 (NCT04604132)
- Testing
- Derazantinib, Derazantinib-paclitaxel-ramucirumab combination
- Where
- 81 sites in United States, Argentina and 13 more
- Volunteers
- 47 people
- Sponsor
- Basilea Pharmaceutica
Risk Factor
Factors Associated With High Mortality of Gastric Adenocarcinoma in Thailand Versus Japan
The differences in patient's clinicopathological characteristic between high and low prevalence of gastric cancer region should be further examined to elucidate factors that associate with poor survival rate of patients with…
- Trial name
- NCT03059732
- Testing
- Treatment
- Where
- Thailand
- Volunteers
- 700 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Overweight or Obesity
The Effect of AMG 133 on Gastric Emptying
The primary objective of the trial is to evaluate the effect of AMG 133 versus placebo on acetaminophen pharmacokinetics (PK), a marker for gastric emptying, in participants living with overweight or obesity.
- Trial name
- NCT07429032
- Testing
- AMG 133, Acetaminophen
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Amgen
Cirrhosis, Liver, Portal Hypertension
Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial.
Research has proven that large varices can be treated with beta-blockers (a type of anti-hypertensive medication) to reduce the pressure in the veins. The management of small varices is still uncertain.
- Conditions
- Cirrhosis, Liver, Portal Hypertension, Variceal Hemorrhage, Varices, Esophageal
- Trial name
- BOPPP (NCT05872698)
- Testing
- Carvedilol
- Where
- United Kingdom
- Volunteers
- 763 people
- Sponsor
- King's College Hospital NHS Trust
Cancer
Irradiated Donor Lymphocyte Infusion in Treating Patients With Relapsed or Refractory Hematologic Cancer or Solid Tumor
RATIONALE: When irradiated lymphocytes from a donor are infused into the patient they may help the patient's immune system kill cancer cells.
- Trial name
- NCT00161187
- Testing
- therapeutic allogeneic lymphocytes
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Gastric Cancer
Prognostic Values of Inflammation-based Indices in Gastric Cancer
This study aims to evaluate the prognostic values of preoperative inflammation-based indices in patients undergoing potentially curative resection of gastric cancer.
- Trial name
- NCT05075421
- Testing
- Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Gulhane Training and Research Hospital
Gastric Cancer
The Safety of Totally Laparoscopic Versus Laparoscopy-Assisted Total Gastrectomy.
To compare the short-term surgical safety and postoperative quality of life of totally laparoscopic versus laparoscopy-assisted total gastrectomy and to evaluate the superiority of totally laparoscopic total gastrectomy.
- Trial name
- NCT04351321
- Testing
- Totally Laparoscopic Total Gastrectomy, Laparoscopy-Assisted Total Gastrectomy
- Volunteers
- 560 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cirrhoses, Liver, Oesophageal Varices
Beta-blockers for Oesophageal Varices
To determine if carvedilol reduces the rate of variceal haemorrhage in patients with cirrhosis and small oesophageal varices
- Trial name
- BOPPP (NCT03776955)
- Testing
- Carvedilol
- Where
- 4 sites in United Kingdom
- Volunteers
- 1,200 people
- Sponsor
- King's College Hospital NHS Trust
Morbid Obesity
Laparoscopic Adjustable Gastric Banding Versus Laparoscopic Sleeve Gastrectomy
The investigators aim to determine the clinical and metabolic outcomes of two available bariatric restrictive procedures: laparoscopic adjustable gastric banding (LAP-BAND) and laparoscopic sleeve gastrectomy for the treatment of…
- Trial name
- NCT00434655
- Testing
- Laparoscopic restrictive procedure
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- North Texas Veterans Healthcare System
Stomach Neoplasms, Gastric Outlet Obstruction
Malignant Gastric Outlet Obstruction Study With Stomach Partitioning (GO-PART)
The goal of this clinical trial is to evaluate whether stomach-partitioning gastrojejunostomy (SPGJ) more effectively reduces postoperative delayed gastric emptying (DGE) compared to conventional gastrojejunostomy (CGJ) in…
- Trial name
- GO-PART (NCT07749326)
- Testing
- Conventional Gastrojejunostomy, Stomach-Partitioning
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Gyeongsang National University Hospital
Gastrointestinal Cancer
Artificial Intelligence and Cancer Staging in Upper Gastrointestinal Malignancies
Esophageal and stomach cancers, which constitute cancers of the upper region of the digestive system, are cancers that are frequently observed and unfortunately have a low rate of cured patients.
- Trial name
- NCT05648084
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sebahattin Celik MD
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