Clinical trials: Stomach Ulcer
Obesity, Gastric Reflux
The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass
The objective of this study is to investigate the effect of Esomeprazol administered in tablets (Esomeprazol MUT Sandoz® 40mg) or in solution (Esomeprazol MUT Sandoz® 40mg in 10ml tap water) on acid production in the gastric…
- Conditions
- Obesity, Gastric Reflux, Ulcer, Gastric
- Trial name
- NCT05320796
- Testing
- upper endoscopy
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Prof Urs Zingg
Peptic Ulcer, Hemorrhage
Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clot
The investigators will include those patients with adherent clot on gastric or duodenal ulcers after endoscopic confirmation After receiving well explanation and giving written consent, they are enrolled and will be allocated to…
- Trial name
- NCT02536989
- Testing
- omeprazole
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Far Eastern Memorial Hospital
Gastric Cancer, Reflux Esophagitis
Preliminary Efficacy Analysis of Cheng's Giraffe Reconstruction After Proximal Gastrectomy
In the past years, the adenocarcinoma of the esophagogastric junction (AEG) has been increasing obviously in China. It may be caused by the reason of increased body weight, alcohol consumption, gastroesophageal reflux disease and…
- Trial name
- NCT04657848
- Testing
- proximal gastrectomy combined with Cheng's Giraffe reconstruction
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhejiang Cancer Hospital
Emergent Surgery, Perforated Peptic Ulcer
Short Term Outcome Following Post Operative Enhanced Recovery Implementation in Patients With Perforated Peptic Ulcer
This study aimed to evaluate the effect of implementing post operative enhanced recovery on perforated peptic ulcer surgery outcome.
- Trial name
- NCT06570018
- Testing
- Post operative enhanced recovery elements
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Gastritis, Gastric Ulcer
A Clinical Trial to Investigate the Safety, Tolerability, Pharmacokinetics, and Food Effect of PMK-S005 After Oral Administration in Healthy Male Volunteers
The Purpose of a randomized, double-blind, placebo-controlled, single-dose, dose-escalation clinical trial is to explore investigate the safety, tolerability, pharmacokinetics, and food effect of PMK-S005 after oral…
- Trial name
- NCT01762397
- Testing
- PMK-S005
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- PharmaKing
Gastric Ulcer, Chronic Gastritis
Helicobacter Rescue Therapy With Berberine Plus Amoxicillin Quadruple Therapy Versus Tetracycline Plus Furazolidone Quadruple Therapy
This study aims at evaluating efficacy and safety of berberine- amoxicillin containing quadruple therapy(berberine, amoxicillin, esomeprazole and bismuth) versus tetracycline-furazolidone quadruple therapy (tetracycline…
- Conditions
- Gastric Ulcer, Chronic Gastritis, Gastric Cancer, Helicobacter Pylori Infection
- Trial name
- NCT03609892
- Testing
- Berberine, Amoxicillin, Esomeprazole
- Where
- China
- Volunteers
- 658 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Duodenal Ulcer, Gastric Ulcer
Lymphocytic Subsets and Cytokine Production With H. Pylori Infection
The aims of this study are 1) to determine the cytokines produced by both Th1 and Th2 subsets in gastric antral biopsy specimens from Taiwanese patients before and after anti H.
- Conditions
- Duodenal Ulcer, Gastric Ulcer, Dyspepsia
- Trial name
- NCT00173953
- Testing
- immune response
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Acute Upper Gastrointestinal Non Variceal Hemorrhage
Endoscopic Diagnosis and Treatment of Acute Nonvariceal Upper Gastrointestinal Bleeding
Acute nonvariceal upper gastrointestinal bleeding (ANVUGIB) is a common critical disease in gastroenterology. Due to the development of modern medical technology, the incidence rate of ANVUGIB has been decreasing in recent years…
- Trial name
- NCT04895904
- Testing
- No intervention
- Volunteers
- 3,200 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Gastric or Duodenal Ulcer
A Study to Evaluate the Pharmacokinetics and Safety Between Single Administration of "BR6002" and Coadministration of "BR6002A" and "BR6002B" Under Fed Conditions in Healthy Adult Volunteers
The purpose of this clinical trial is evaluate the pharmacokinetics and safety between single administration of "BR6002" and coadministration of "BR6002A" and "BR6002B" under fed conditions in healthy adult volunteers
- Trial name
- NCT05959499
- Testing
- BR6002A, BR6002B, BR6002
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boryung Pharmaceutical Co., Ltd
Peptic Ulcer, Dyspepsia
HEP-FYN 12-Years Follow-up
Aims: 1. Evaluate the long-term effect of screening and eradication of Helicobacter Pylori on the prevalence of dyspepsia, and, as secondary outcomes, to assess the effect on dyspepsia related health-care consumption and quality…
- Conditions
- Peptic Ulcer, Dyspepsia, Reflux
- Trial name
- NCT02001727
- Testing
- 13C-Urea breath test for Helicobacter Pylori, Questionaire
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Surgery, Emergencies
Laparoscopic Versus Open Repair of Peptic Ulcer Perforation
Although laparoscopic repair (LR) of perforated peptic ulcers (PPUs) has long been accepted, clinical evidence comparing LR versus open repair (OR) remains lacking.
- Conditions
- Surgery, Emergencies, Peptic Ulcer Perforation
- Trial name
- LOREPUP (NCT04447170)
- Testing
- Simple repair or Graham technique
- Where
- 13 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Gianluca Costa
Gastroesophageal Reflux Disease With Esophagitis
Evaluate the Intestinal Microbiome in Patients With Erosive Gastroesophageal Reflux Disease and in Asymptomatic Healthy Controls
. In this study, we investigated intestinal microbiomes, in individuals with Gastroesophageal Reflux Disease and healthy individuals, using metagenomic techniques.
- Trial name
- NCT04248296
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Gastroesophageal Reflux Disease
Mass Balance Study of [14C]X842 in Healthy Adult Male Subjects
This study is a single-site, single-dose, non-randomized, open-label study to assess the absorption, metabolism, and excretion profile of [14C]X842 in healthy adult male subjects.
- Trial name
- NCT07107672
- Testing
- [14C]X842
- Where
- China
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Jiangsu Sinorda Biomedicine Co., Ltd
Gastroduodenal Ulcer
Hemostatic Forceps vs. Bipolar Electrocautery Probes for High-Risk Bleeding Gastroduodenal Ulcers
A randomized controlled trial to evaluate the efficacy of hemostatic forceps and bipolar electrocautery probes in patient with high risk bleeding gastroduodenal ulcers.
- Trial name
- NCT06393907
- Testing
- Hemostatic Forceps, Bipolar Electrocautery Probes
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Mahidol University
Tuberculosis, Gastric Cancer
Volatiles in Breath and Headspace Analysis - Diagnostic Markers
Detection of Volatile Organic Compounds (VOC) directly from tissue by headspace analysis (skin, surgery material, other tissue) and exhaled breath is feasible using affordable user-friendly novel nano-chemo sensors that can…
- Conditions
- Tuberculosis, Gastric Cancer, Peptic Ulcer, Atrophic Gastritis
- Trial name
- Volatolome (NCT03228095)
- Testing
- VOC detection in breath and in skin headspace, Breath sampling, Upper endoscopy with biopsies
- Where
- Latvia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Latvia
Peptic Ulcer, NSAID-Induced Peptic Ulcer
Fexuclue for Prevention of NSAIDs-Induced Peptic Ulcer in Real-World Practice
This study is a prospective, multi-center, observational study to evaluate the efficacy and safety of Fexuclue Tablet 20 mg in patients requiring prevention of NSAIDs-induced peptic ulcer in real-world clinical practice in Korea.
- Trial name
- NCT07558707
- Where
- South Korea
- Volunteers
- 7,000 people
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
Stomach Ulcer, Gastroesophageal Reflux
Pharmacodynamics and Safety of CDFR0209
This is a randomized, open-label, two-way crossover study to investigate the pharmacodynamics(24 hour gastric pH) and the safety between repeated doses of CDFR0209 and Losec in Healthy Male Volunteers
- Trial name
- NCT02710994
- Testing
- CDFR0209, Losec
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Peptic Ulcer Perforation
Peptic Ulcer Perforation Study
The objective of this study is to implement an optimized perioperative course for patients surgically treated for peptic ulcer perforation in order to improve the outcome for these patients.
- Trial name
- PULP (NCT00624169)
- Testing
- An optimized perioperative course
- Where
- 7 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital at Herlev
Complications, Quality of Life
Double Tract Anastomosis and Gastric Tube Anastomosis to Proximal Gastrectomy
Gastric cancer as one of the most common gastrointestinal cancers, radical resection of primary lesions combined with dissection of regional lymph-nodes is acknowledged by surgeons all over the world.
- Conditions
- Complications, Quality of Life, Remnant Gastritis, Reflux Esophagitis
- Trial name
- DTA>A (NCT02288728)
- Testing
- Gastric tube anastomosis, Double-track anastomosis
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Jian-Kun Hu
Peptic Ulcer
Natural History of Non-steroidal Anti-inflammatory Drug and Non-Helicobacter Pylori in Bleeding Peptic Ulcers
The aim of this study is to study the natural history of the ulcer healing while on proton pump inhibitors (PPI) and the ulcer recurrence without acid suppression therapy of Non-steroidal Anti-inflammatory Drugs (NSAID)…
- Trial name
- NCT00153712
- Where
- China
- Volunteers
- 391 people
- Sponsor
- Chinese University of Hong Kong