Clinical trials: Stomach Ulcer
Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight
The Transit Bipartition With the Use of a Metallic Anastomosis Clip and Circular Fundocorporeal Gastroplication
This study evaluates a new surgical device - the Metallic Anastomotic Clip (MAC) - for performing a laparoscopic bypass gastroenteroanastomosis with entero-enteric anastomosis (transit bipartition / "dual-path" procedure) in…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Obesity & Overweight, Marginal Ulcer (Peptic) or Erosion, Leakage, Anastomotic
- Trial name
- MACBIPARTFCG (NCT07495020)
- Testing
- Laparoscopic transit bipartition with Metallic Anastomotic Clip and Circular Fundocorporeal Gastroplication, Laparoscopic transit bipartition (gastroenteroanastomosis and entero-enteric anastomosis) use the Metallic Anastomotic Clip and with sleeve gastrectomy, laparoscopic duodenal transit bipartition using the Metallic Anastomotic Clip with circular fundocorporeal gastroplication without gastrectomy
- Where
- Kazakhstan
- Volunteers
- 90 people
- Sponsor
- The Society of Bariatric and Metabolic Surgeons of Kazakhstan
Gastrinoma, Zollinger Ellison Syndrome
The Use of Oral Omeprazole and Intravenous Pantoprazole in Patients With Hypersecretion of Gastric Acid
Patients with Zollinger-Ellison Syndrome suffer from ulcers of the upper gastrointestinal tract, higher than normal levels of gastric acid, and tumors of the pancreas known as non-beta islet cell tumors.
- Trial name
- NCT00001191
- Testing
- Pantoprazole, Omeprazole
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Esophagitis, Reflux
Assessment of GERD Knowledge Level Among Patients With it in Korea
1. Research topic: How much do patients with GERD know about their own disease in Korea? (multicenter survey) 2. Questionnaires for multicenter survey: 1.
- Trial name
- GERD (NCT02049723)
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Peptic Ulcer Hemorrhage
Effects of 2 Different Doses of Pantoprazole on Gastric pH and Recurrent Bleeding in Patients Who Bled From Peptic Ulcers
Endoscopic treatment of bleeding peptic ulcers is effective to prevent rebleeding. Adjuvant medical treatment to increase gastric pH may further decrease rebleeding.
- Trial name
- NCT00279123
- Testing
- pantoprazole infusion, pantoprazole bolus, no treatment
- Where
- China
- Sponsor
- Kwong Wah Hospital
NSAID Associated Gastric Ulcers
A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is Continued in Subjects in the US Only
Nonsteroidal anti-inflammatory drugs (NSAIDS) are often associated with gastric ulcers. This study looks at the treatment of these gastric ulcers with one of the three following treatment groups for up to 8 weeks: esomeprazole 40…
- Trial name
- NCT00633412
- Testing
- Esomeprazole, Ranitidine
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Duodenal Ulcer
Comparison of TAK-438 (Vonoprazan) to Lansoprazole in the Treatment of Duodenal Ulcer Participants With or Without Helicobacter Pylori Infection
The purpose of this study is to demonstrate the non-inferior efficacy of TAK-438 versus lansoprazole in the treatment of participants with duodenal ulcer.
- Trial name
- NCT03050359
- Testing
- TAK-438, Lansoprazole, Bismuth-Containing Quadruple Therapy
- Where
- 81 sites in China, Philippines and 2 more
- Volunteers
- 533 people
- Sponsor
- Takeda
Peptic Ulcer Perforation, Perforated Bowel
ERAS vs Conventional Approach in Peptic Perforation-RCT
This study compares 2 different ways of perioperative management in patients of peptic perforation. Experimental arm is the ERAS arm( Enhanced recovery after surgery) and the comparative arm is Conventional arm.
- Conditions
- Peptic Ulcer Perforation, Perforated Bowel, Post-Op Complication, Emergencies
- Trial name
- ERASE (NCT04194060)
- Testing
- Enhanced Recovery after Surgery group, Conventional
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Peptic Ulcer
Importance of Cytokines in Peptic Ulcer Disease: Implications for Treatment
Although all PPIs are effective, there are some differences in their clinical performance, particularly in terms of the degree and speed of gastric acid suppression.
- Trial name
- NCT00534443
- Testing
- Endoscopy of upper GI tract
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- University of Athens
Gastric Ulcer, Duodenal Ulcer
Comparison of Ulcer Healing in Patients Taking Rabeprazole With Different Antiplatelets
Clopidogrel causes significantly less peptic ulcer disease (PUD) and ulcer bleeding than low-dose aspirin in general population.
- Trial name
- NCT01037491
- Testing
- rabeprazole plus aspirin versus rabeprazole plus clopidogrel
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Peptic Ulcer
Esomeprazole Versus Pantoprazole to Prevent Peptic Ulcer Rebleeding
The aim of this study is to compare the clinical effectiveness of intravenous esomeprazole and pantoprazole in preventing recurrent bleeding in the patients with high-risk bleeding peptic ulcers after successful standard…
- Trial name
- NCT00881413
- Testing
- Esomeprazole, Pantoprazole
- Sponsor
- Lotung Poh-Ai Hospital
Helicobacter Pylori Infection, Gastric Ulcer
A Study on the Gastrointestinal Disease and Helicobacter Pylori Controlled Long Non-coding RNA
Helicobacter pylori (H.pylori) is a major human pathogenic bacterium in gastric mucosa which is linked to the development of gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue lymphoma and gastric cancer.
- Conditions
- Helicobacter Pylori Infection, Gastric Ulcer, Duodenal Ulcer, Stomach Cancer
- Trial name
- NCT03057171
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Peptic Ulcer Bleeding
Tegoprazan And Lansoprazole Effectiveness in Bleeding Peptic Ulcer Treatment
The goal of this clinical trial is to compare the effects of tegoprazan vs lansoprazole in healing bleeding peptic ulcers. It will also teach about the safety of both modalities.
- Trial name
- TALENT (NCT06894992)
- Testing
- Tegoprazan, Lansoprazole
- Where
- 2 sites in Indonesia
- Volunteers
- 162 people
- Sponsor
- Mario Steffanus
Pain
Safety, Tolerability and Efficacy Study With a Fixed-Dose Combination (FDC) Ketoprofen Plus Omeprazole
Primary Objective: To confirm the safety and tolerability of the fixed dose combination of a Non-Steroidal Anti-Inflammatory Drug (NSAID), ketoprofen, associated to a Proton Pump Inhibitor (PPI), omeprazole, in Mexican patients.
- Trial name
- NCT00971581
- Testing
- FDC KETOPROFEN+OMEPRAZOLE
- Where
- Mexico
- Volunteers
- 52 people
- Sponsor
- Sanofi
Peptic Ulcer
A Comparison of Two Therapeutic Strategies for the Treatment of Aspirin-associated Peptic Ulcers
Esomeprazole plus aspirin compared with esomeprazole alone for the treatment of aspirin-related peptic ulcers.
- Trial name
- NCT01353144
- Testing
- aspirin
- Where
- 3 sites in Taiwan
- Volunteers
- 178 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Zollinger Ellison Syndrome
Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome
This protocol concerns the approach to the localization, diagnosis of MEN1 and management of the tumor and the tissue samples in patients with Zollinger-Ellison syndrome.
- Trial name
- NCT00001254
- Where
- United States
- Volunteers
- 273 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Peptic Ulcers, Upper Gastrointestinal Bleeding
High Versus Standard Dose of Proton Pump Inhibitors (PPIs) in Peptic Ulcer Bleeding
High intravenous dosage of Proton Pump Inhibitors is not better than standard dosage in bleeding peptic ulcers successfully treated by endoscopic therapy
- Trial name
- NCT00374101
- Testing
- omeprazole, pantoprazole
- Where
- 10 sites in Italy
- Volunteers
- 450 people
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Duodenal Ulcer Due to Helicobacter Pylori
The Efficacy and Safety of Ilaprazole/Doxycycline-based Bismuth-containing Quadruple Therapy on Hp Infected Duodenal Ulcers
Helicobacter pylori (Hp) infection is one of the important causes of gastrointestinal diseases, including gastritis, peptic ulcer, and malignancies, nd the eradication of Hp can effectively cure or prevent these diseases.
- Trial name
- NCT03342456
- Testing
- Doxycycline Hyclate Enteric-Coated Capsules, Amoxicillin Capsules, Ilaprazole Enteric-Coated Tablets
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Islet Cell Adenoma, Neoplasm Metastasis
Combination Chemotherapy in Patients With Zollinger-Ellison Syndrome and Tumors of the Pancreas
Patients with Zollinger-Ellison Syndrome suffer from ulcers of the upper gastrointestinal tract, higher than normal levels of gastric acid, and tumors of the pancreas known as non-beta islet cell tumors.
- Conditions
- Islet Cell Adenoma, Neoplasm Metastasis, Zollinger Ellison Syndrome
- Trial name
- NCT00001165
- Testing
- combined chemotherapy with streptozotocin, 5-fluorouracil, and doxorubicin
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NSAID Associated Gastric Ulcers
A Comparative Efficacy and Safety Study of Nexium Delayed-Release Capsules (40mg qd and 20mg qd) Versus Ranitidine 150mg Bid for the Healing of NSAID-Associated Gastric Ulcers When Daily NSAID Use is Continued
Nonsteroidal anti-inflammatory drugs (NSAIDS) are often associated with gastric ulcers. This study looks at the treatment of these gastric ulcers with one of the three following treatment groups: esomeprazole 40 mg once daily…
- Trial name
- NCT00633672
- Testing
- Esomeprazole, Ranitidine
- Volunteers
- 400 people
- Sponsor
- AstraZeneca
Esophagitis, Reflux, Esophagitis, Peptic
Efficacy and Safety of Dexlansoprazole MR on Maintaining Healing in Subjects With Healed Erosive Esophagitis
The purpose of this study is to assess the ability of once-daily (QD) treatment with Dexlansoprazole modified-release (MR) 60 mg and 90 mg and placebo in maintaining healing of erosive esophagitis (EE).
- Trial name
- NCT00255164
- Testing
- Dexlansoprazole MR
- Where
- 96 sites in United States
- Volunteers
- 451 people
- Sponsor
- Takeda