Clinical trials: Stomatitis
Childhood Oncology, Mucositis Oral
Oral Mucositis Management in Pediatric Oncology Patients
This study evaluated the impact of an oral mucositis care protocol on the severity of mucositis. The main questions it aims to answer are: -What is the severity of mucositis in parents and children who receive oral mucositis…
- Trial name
- NCT06711315
- Testing
- Oral Mucosit Care Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Zubeyde Ezgi Ercelik
Radiation-Induced Mucositis
Efficacy of Glutamine in Management of Radiation Mucositis
The goal of this [ type of study: Clinical trial] is to test effectiveness of glutamine in management of Radiation Induced Mucositis in head and neck cancer patients.
- Trial name
- NCT05856188
- Testing
- Glutamine
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Radiation-induced Oral Mucositis, Oral Malignancy
A Phase II Prospective, Open-Label, Randomized, Multicenter Study of Kangfu Spray for the Prevention of Radiation-Induced Oral Mucositis in Patients With Oral Malignancies Receiving Intensity-Modulated Radiotherapy
This is a prospective, open-label, randomized, controlled, multicenter phase II study evaluating the efficacy and safety of Kangfu Spray for the prevention of radiation-induced oral mucositis in patients with histologically…
- Trial name
- NCT07538934
- Testing
- Kangfu Spray, Standard Oral Care
- Volunteers
- 140 people
- Sponsor
- YE ZHANG
Recurrent Aphthous Stomatitis, Mouth Ulcer
The Preventive and Therapeutic Effects of Spirulina Preparations on Ulcers of Oral Mucosa
This is a prospective, randomized, double-blind, placebo-controlled clinical trial designed to evaluate the efficacy and safety of spirulina supplementation in patients with radiation-induced oral mucositis (RIOM) receiving…
- Trial name
- NCT07723612
- Testing
- Spirulina Tablets
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Oral Mucositis
Effects for Oral Mucositis Care During Chemoradiotherapy in Cancer Patients: Evaluation of the Bee Products
Oral mucositis is common among cancer patients receiving radiotherapy and chemotherapy. 80-90% of the patients are suffering from the mucositis pain; poor nutrition and even treatment discontinued.
- Trial name
- Mucositis (NCT05625841)
- Testing
- Honey product, propolis, Usual care
- Where
- Taiwan
- Volunteers
- 135 people
- Sponsor
- Taipei Medical University
Radiation-Induced Mucositis, Head and Neck Cancer
Curcumin Gel On Radiation Induced Oral Mucositis
The goal of this clinical study is to investigate the effect of a curcuma longa oral gel (curenext) on reducing radiation-induced oral mucositis severity in cancer patients and provide a context for understanding if there is a…
- Trial name
- NCT05982197
- Testing
- Curcumin Gel, Standard Preparation
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- University of Baghdad
Radiation Induced Oral Mucositis
Benzydamine vs Supersaturated Calcium Phosphate Oral Rinses for Radiation Induced Oral Mucositis in Head and Neck Cancer Patients.
The goal of this clinical trial is to compare and correlate salivary macrophage migratory inhibitory factor levels with onset and severity of radiation induced mucositis in head and neck cancer patients by using super saturated…
- Trial name
- NCT07748442
- Testing
- Benzydamine hydrochloride mouthrinse, Super saturated calcium phosphate oral rinses
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Malignant Solid Tumour
Ph1 Administration of VSV-IFNβ-NIS Monotherapy and in Combination With Avelumab in Pts With Refractory Solid Tumors
This is a three-part open label phase 1 study designed to determine the safety profile, MTD, PK and tumor and biomarker response after IT or IV administration of a single dose of VSV-IFNβ-NIS, or combined IT followed by IV…
- Trial name
- NCT02923466
- Testing
- VSV-IFNβ-NIS, VSV-IFNβ-NIS and avelumab
- Where
- 6 sites in United States
- Volunteers
- 76 people
- Sponsor
- Vyriad, Inc.
Oral Mucositis
Multi-centre, Open-label, First-in-man Study With Mucopad HA
The device´s intended use is to treat defects and/or lesions of the oral mucosa, e.g. oral mucositis.To prove safety of the device in terms of clinical results.
- Trial name
- NCT06276270
- Testing
- Mucopad HA
- Where
- 5 sites in Czechia
- Volunteers
- 50 people
- Sponsor
- Contipro Pharma a.s.
Melanoma, Head and Neck Squamous Cell Carcinoma
Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients
This is a Phase 2 study designed to determine the preliminary anti-tumor activity and confirm the safety of VV1 in combination with cemiplimab. The study will enroll patients with three distinct separate tumor cohorts.
- Conditions
- Melanoma, Head and Neck Squamous Cell Carcinoma, Colo-rectal Cancer
- Trial name
- NCT04291105
- Testing
- VV1, Cemiplimab
- Where
- 13 sites in United States, Brazil
- Volunteers
- 87 people
- Sponsor
- Vyriad, Inc.
Head and Neck Neoplasms, Chemoradiotherapy
Evaluation the Effects of Herbal Gargle for Chemoradiotherapy-induced Oral Mucositis of Head & Neck Cancer, a Pilot Study.
The aim of the study is to evaluate the effects of Herbal gargle on chemoradiotherapy-induced stomatitis in head \& neck cancer patients.
- Conditions
- Head and Neck Neoplasms, Chemoradiotherapy, Stomatitis and Ulceration
- Trial name
- NCT05341206
- Testing
- Herbal gargle, Normal saline
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Oral Mucositis, Stomatitis
Prospective Study of Head and Neck Cancer Radiation Treatment With or Without Amifostine
The purpose of this study is to compare the incidence of stomatitis when treating with amifostine before radiation treatment.
- Trial name
- NCT01288625
- Testing
- Amifostine
- Sponsor
- Sun Pharmaceutical Industries Limited
Inflammation of Mouth
Association of Periodontal Inflammation on Immune Response in Wound Healing
Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken.
- Trial name
- NCT04805320
- Testing
- Dental Extraction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Stomatitis, Aphthous
Comparison of Hypericum Perforatum, Topical Corticosteroids, and Hyaluronic Acid for Recurrent Aphthous Stomatitis
Recurrent aphthous stomatitis (RAS) is one of the most common ulcerative diseases of the oral mucosa and is characterized by recurrent painful ulcers that adversely affect eating, speaking, and overall quality of life.
- Trial name
- NCT06839313
- Testing
- Kenacort A Orabase® pomad , Bristol-Myers Squibb İlaçları Inc. İstanbul , Türkiye, Hyaluronic acid, Aftamed ® Oral jel , AktiFarma . İstanbul, Türkiye, Hypericum perforatum (St. John's wort oil, Zade Vital; Health&Fitness, Developed With Ege Üniversiesi Argefar)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Batman University
Oral Mucositis, Pain
Cryotherapy for Prevention of Oral Mucositis in Children Undergoing Hematopoietic Stem Cell Transplantation
Oral mucositis (OM) is a common adverse effect of chemotherapy, radiotherapy and conditioning regimens before Hematopoietic Stem Cell Transplantation (HSCT).
- Conditions
- Oral Mucositis, Pain, Infection, Nutrition Aspect of Cancer
- Trial name
- NCT01789658
- Testing
- Cryotherapy
- Where
- 5 sites in Sweden
- Volunteers
- 53 people
- Sponsor
- Uppsala University
Oral Mucositis
A Mouthwash Medicine for the Reduction or Prevention of Mouth Ulceration Caused by Radiotherapy for Head and Neck Cancer
This study is looking at a new medication called NG11-2 to see if it can reduce a side effect called severe Radiation-induced Oral Mucositis (RIOM) that can happen to people getting radiation treatment for head and neck cancer.
- Trial name
- NCT06669390
- Testing
- NG11-2
- Where
- 4 sites in United Kingdom
- Volunteers
- 15 people
- Sponsor
- VasoDynamics Ltd
Mucositis, Hematopoietic Stem Cell Transplantation
Cryotherapy in the Prevention of Chemotherapy-Induced Mucositis in Stem Cell Transplant
Oral mucositis is a common complication of cancer therapy. Mucositis results from damage to the mucosal epithelium after delivery of chemotherapy or radiation treatments designed to treat the cancer.
- Conditions
- Mucositis, Hematopoietic Stem Cell Transplantation, Peripheral Blood Stem Cell Transplantation, Stomatitis
- Trial name
- NCT02326675
- Testing
- Ice, Normal Saline Solution
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Florida
Head and Neck Cancer Patients Treated With Radiotherapy
Evaluation of the Efficacy of Aloe-Vera el Versus Bezydamine Hydrochloride in the Prevention of Radiation Induced Oral Mucositis A Randamized Controlled Clinical Trial
Background and Rationale Oral mucositis (OM) is one of the most debilitating toxic side effects of radiotherapy and chemotherapy.
- Trial name
- NCT06879366
- Testing
- Aloe vera gel, Benzydamine Hydrochloride 0.15% Oral gel
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Pemphigus, Bullous Pemphigoid
Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Pemphigus is a rare autoimmune life-threatening blistering condition affecting skin and mucous membranes. Pemphigus belongs to a family of polygenic disorders.
- Conditions
- Pemphigus, Bullous Pemphigoid, Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
- Trial name
- NCT05284929
- Testing
- A single blood sample for HLA typing
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sechenov University
Oral Mucositis, Quality of Life
Thalidomide With or Without Probiotics in Radioactive Oral Mucositis
Study on the application of thalidomide with or without probiotics in radioactive oral mucositis
- Trial name
- NCT05059613
- Testing
- probiotics
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jiangxi Provincial Cancer Hospital