Clinical trials: Stomatognathic Disease
Caries, Dental, Risk Reduction
Using a Mouthwash Containing Propolis, Clove Oil and Chlorhexidine to Improve the Caries Risk of High Risk Patients
This study is conducted to determine if using a mouthwash containing propolis, clove oil and chlorhexidine will improve the caries risk of high risk patients in comparison to using a mouthwash containing chlorhexidine only.
- Trial name
- NCT03553628
- Testing
- Chlorhexidine, Propolis and Clove Oil mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Moataz Gamal Ali Abdul-Maksoud Konsouh
Caries,Dental
CARDEC-PEL: Comparison of Two Methods of Caries Risk Assessment in Children
The aim of the study was to compare dental caries treatment and follow-up based on an elaborate and individualized assessment of caries risk in children, to a simpler risk assessment strategy by means of a double-blind randomized…
- Trial name
- NCT03969628
- Testing
- ICCMS
- Where
- Brazil
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Generalized Aggressive Periodontitis, Chronic Periodontitis
Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods
Generalized aggressive Periodontitis (GAgP) and chronic periodontitis (CP) are inflammatory diseases. Little is known about molecular changes and signaling cascade of host response.
- Trial name
- NCT04026828
- Testing
- Periodontitis Group
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Chronic Periodontitis, Diabetes Mellitus
Effects of Adjunct Photodynamic Therapy in the Treatment of Type 2 Diabetic Patients With Chronic Periodontitis
Periodontal Diseases are considered the sixth complication of Diabetes Mellitus (DM). This close relationship between both diseases is characterized by mutual influence.
- Trial name
- NCT02627534
- Testing
- Ultrasonic debridement, Antimicrobial photodynamic therapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Dental Caries
Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Lesions
This study will be conducted to evaluate and compare the clinical performance of fluoride, calcium, and phosphate-releasing new bioactive material versus a fluoride-releasing hybrid restorative material in cervical lesions for…
- Trial name
- NCT05149209
- Testing
- cervical restoration
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
Densah Burs vs. Electrical Mallet in Closed Sinus Lifting.
The aim of the comparative study is to evaluate the density and amount of new bone formed (bone height gain)around dental implant placed simultaneously in posterior maxilla after closed sinus floor elevation using…
- Trial name
- NCT06180187
- Testing
- Electrical mallet, Osseo-densification burs
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Periodontal Disease
Assessment of the Efficacy and Safety of OROXID® Oral Solution in Patients With Periodontitis
Periodontitis is a chronic, irreversible inflammatory disease affecting the supporting structures of the teeth. It is most commonly caused by bacteria in dental plaque, also known as biofilm.
- Trial name
- OroxParodont (NCT07257887)
- Testing
- OROXID® forte oral solution, OROXID® sensitive oral solution, Standard of Care
- Where
- 2 sites in Slovenia
- Volunteers
- 90 people
- Sponsor
- ENIKAM d.o.o.
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Crowding, Tooth
Evaluating the Influence of Showing Patients Their Predicted Teeth Alignment on Their Expectations and Satisfaction
Patients who have moderate crowding will be treated in this study. The efficacy of showing the predicted alignment of patient's teeth at the end of orthodontic treatment previously to treatment on their expectations from…
- Trial name
- NCT05010616
- Testing
- Fixed orthodontic appliances
- Where
- Syria
- Volunteers
- 25 people
- Sponsor
- Damascus University
Tonsillitis, Tonsillectomy
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy
The purpose of this pilot study: 1) to examine the use of gabapentin in reducing pain in the first 48 hours postoperatively including the total amount of narcotics mg/kg given 2) to record the time to first analgesic…
- Trial name
- NCT03625011
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Healthcare of Atlanta
Periapical Periodontitis, Bacterial Infections
Adjunctive Steps for Disinfection of Teeth With Primary Endodontic Infections
This study aims to evaluate an endodontic treatment protocol using adjunctive steps for disinfection of teeth with primary endodontic infections.
- Trial name
- NCT03537664
- Testing
- Root canal preparation, Intracanal medication
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo
Periodontal Diseases, Periodontitis
Evaluation of the Effects of Probiotic Toothpastes on Periodontal Health
This controlled, randomized clinical study aims to evaluate the possible effects of probiotic toothpaste on the success of periodontal treatment in smokers and non-smokers with clinical data.
- Conditions
- Periodontal Diseases, Periodontitis, Gingivitis
- Trial name
- NCT06514664
- Testing
- Using Probiotic Toothpaste
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Muscle Strength, Neck Muscle Issue
The Cranio-cervical Flexion Test Using the NOD Device
to measure strength of the deep anterior neck muscles with a new measurement protocol and by using the NOD device, a dynamometer, in subjects with and without bruxism, and compared to EMG on the superficial muscles of the…
- Conditions
- Muscle Strength, Neck Muscle Issue, Bruxism, EMG
- Trial name
- CCFT-NOD (NCT06037798)
- Testing
- cranio-cervical flexion test with NOD
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Zurich University of Applied Sciences
Dental Pain
Anesthetic Effectiveness of Lidocaine Versus Articaine in Dentistry
Context: Lidocaine and articaine are two of the most commonly used local anesthetics in dentistry. Lidocaine has often been the anesthetic of choice in clinical practice, but in clinical experience, articaine has proven to be…
- Trial name
- NCT07231614
- Testing
- lidocaine + epinephrine 1:100,000, Articaine 4% with epinephrine 1:100,000
- Where
- Chile
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Measles, Mumps
Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Children in Their Second Year of Life
The purpose of this study is to evaluate end of shelf-life potency in terms of the immunogenicity and safety of GSK Biologicals' trivalent MMR vaccine, by comparing it to Merck \& Co., Inc.'s MMR vaccine, which is approved for…
- Conditions
- Measles, Mumps, Rubella, Measles-Mumps-Rubella Vaccine
- Trial name
- NCT01681992
- Testing
- Priorix, M-M-R II, Varivax
- Where
- 81 sites in United States, Czechia and 5 more
- Volunteers
- 4,538 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Alveolar Bone Loss
Evaluation of Short Implants' Success for Teeth Replacement in Atrophic Posterior Mandibular Ridge
The aim of this study was to evaluate clinically and radiographically the splinted short implants' and single short implants' stability and bone condition before and after loading, in atrophic posterior mandibular alveolar ridges.
- Trial name
- NCT04414709
- Testing
- Double short implant, Single short implant
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Pharyngitis, Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Comparative Trial of Azithromycin Sustained Release Versus 3-Day Azithromycin for the Treatment of Strep Throat in Adolescents and Adults
To determine if a single 2.0-g dose of azithromycin SR is at least as effective as a 3-day course of azithromycin (500 mg once daily for 3 days) when used to treat adolescents and adults with strep throat, and to assess efficacy…
- Trial name
- NCT00644293
- Testing
- azithromycin (Zithromax), azithromycin SR
- Where
- 59 sites in United States, Belgium and 8 more
- Volunteers
- 598 people
- Sponsor
- Pfizer
Gingival Inflammation
Evaluation of The Effect of Live Probiotic Cultures Present in Fermented Dairy Product (Yogurt) Versus The Effect of Freeze-Dried Probiotic Sachets on Gingival Bleeding of Adolescents
To evaluate the effect of probiotics supplied in two different forms (dairy products containing probiotics as yogurt and freeze-dried synthetic probiotics sachets) on improving gingival condition and caries potentiality of dental…
- Trial name
- NCT03640065
- Testing
- freeze-dried probiotic sachets, fermented dairy product ( yogurt)
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingivitis
Clinical Evaluation and Assesment of Ginigivitis Patients Treated by Yarrow Natural Extract in Compare to a Contro Group
A double-blind, prospective, randomized, intra-individual comparative, single-center clinical study was conducted. Participants were placed in parallel groups, and the study was performed in the Department of Operative Dentistry…
- Trial name
- NCT06070571
- Testing
- Yarrow and moringa mixture
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Deraya University
Molar Incisor Hypomineralization, Anesthesia, Local
Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars
The purpose of this randomized, controlled clinical study is to evaluate if application of 38% SDF increases the efficacy of local anesthesia during operative dentistry on permanent molars affected by molar-incisor hypoplasia…
- Trial name
- NCT05964387
- Testing
- SDF
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Michigan
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