Clinical trials: Stomatognathic Disease
Periodontal Disease, Preterm Birth
Periodontal Disease and Preterm Birth
To determine the relationship between periodontal disease and upper genital tract inflammation in pregnancy. To determine whether certain fluid levels in the oral cavity and the vagina are associated with preterm birth or…
- Conditions
- Periodontal Disease, Preterm Birth, Low Birth Weight
- Trial name
- NCT00582374
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Gingival Diseases
Clinical Study to Evaluate Dental Plaque
Clinical research study to determine anti-plaque efficacy of a prototype toothpastes for a 3 week brushing regiment.
- Trial name
- NCT00758290
- Testing
- Triclosan/Fluoride, Fluoride/triclosan
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontitis
Growth Factors Release of PRF and PRGF
Background: platelet concentrate could enhance growth factors (GF) crevicular fluid levels which might be crucial to proper tissue repair and wound healing.
- Trial name
- NCT02447510
- Testing
- group 1 bio-oss bone xenograft, group 2 platelet rich in growth factor (autogenous platelet rich in growth factor), group 3 platelet rich fibrin (autogenous platelet rich fibrin)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gingival Recession, Recession, Gingival
Coronally Advanced Flap With Alloderm Versus Coronally Advanced Flap With Micro-needling on RT1 Gingival Recession
This study aims to assess the effect of micro-needling together with coronally advanced flap procedure on the gain of gingival thickness (GT) and keratinized tissue width (KTW) and compare it to Alloderm with coronally advanced…
- Conditions
- Gingival Recession, Recession, Gingival, Thin-gingiva
- Trial name
- NCT05470660
- Testing
- Root coverage using coronally advanced flap combined with micro-needling, coronally advanced flap combined with Alloderm
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontitis
Periodontal Phenotype and Scaling and Root Planing
Periodontal phenotype has been recognized as one of the key factors that may potentially impact the outcome of a variety of periodontal surgical and non-surgical procedures.
- Trial name
- NCT05449938
- Testing
- Scaling and root planing
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Chronic Periodontitis, Aggressive Periodontitis
B Cell Functions in Periodontitis
The inflammatory response involves many players from the immune response, including B lymphocytes. These cells are responsible for the synthesis of immunoglobulins in response to the presence of an antigen.
- Trial name
- LBPARO (NCT02833285)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
General Anesthesia
Heated Circuit on Sore Throat
This investigation is planned to compare the incidence and severity of postoperative sore throat according to the use of heated breathing circuit in patients undergoing endotracheal intubation for general anesthesia.
- Trial name
- NCT03693417
- Testing
- Heated circuit on, Heated circuit off
- Volunteers
- 92 people
- Sponsor
- Keimyung University Dongsan Medical Center
Periodontitis
Allogeneic Dental Pulp Stem Cells for the Treatment of Periodontitis
The overall objective of this study is to evaluate the safety and efficacy of allogeneic human dental pulp stem cells (DPSCs) injected for the treatment of chronic periodontitis in humans.
- Trial name
- NCT07574840
- Testing
- Allogeneic Dental Pulp Stem Cells for the Treatment of Periodontitis
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Dental Diseases
Music During Dental Children Care Under MEOPA
In France, the improvement of dental care for children in general and even more so for children with special needs is a real public health issue.
- Trial name
- SONOMEOPAeDENT (NCT05720689)
- Testing
- using relaxing music, No relaxing music
- Where
- 6 sites in France
- Volunteers
- 177 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Nasopharyngeal Carcinoma
Reduced-dose Versus Standard Dose Radiotherapy for Nasopharyngeal Carcinomain
To study the 2-year PFS (progression-free survival) of patients with stage II-III nasopharyngeal carcinoma treated with induction chemotherapy followed by two different doses of intensity modulated radiation therapy plus…
- Trial name
- NCT05304468
- Testing
- IMRT, induction chemotherapy, cisplatin concurrent chemotherapy
- Where
- China
- Volunteers
- 452 people
- Sponsor
- Sun Yat-sen University
Subcondylar Process of Mandible Open Fracture, Facial Nerve Injuries
Evaluation of Preauricular Retromandibular Anteroparotid Versus Retromandibular Through Parotid Approach
Of all the bones in the maxillofacial area, the condylar process is the most susceptible to fracture. The incidence of condylar fracture accounts for 25% to 50% of all mandibular fractures.
- Trial name
- NCT03803150
- Testing
- PRA approach, RT approach
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Extubation Success, Craniofacial Pain Syndrome
The Predictive Value of Peak Cough Flow for Endotracheal Extubation of Patients After Craniotomy
In severe cases after craniotomy, tracheal intubation is often required, and the removal of tracheal intubation presents certain risks and challenges.
- Conditions
- Extubation Success, Craniofacial Pain Syndrome, Cough Peak Flow, Endotracheal Tube
- Trial name
- PCFET (NCT04000997)
- Where
- China
- Volunteers
- 785 people
- Sponsor
- Beijing Tiantan Hospital
Jaw, Edentulous, Partially
Study of Bone Preservation When OsseoSpeed™ Implants Are Placed Immediately Following Tooth Extraction
The purpose of this study is to evaluate the clinical performance of implants placed in individuals who are about to loose one or more of their upper teeth.
- Trial name
- NCT00711282
- Testing
- OsseoSpeed™
- Where
- 3 sites in Italy, Spain and 1 more
- Volunteers
- 104 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus
Disruption of Immune Homeostasis in Type 2 Diabetics With Generalized Chronic Periodontitis
The primary objective of this study is to assess the short-term immune response of type-2 diabetics with generalized chronic periodontitis (GCP) to nonsurgical periodontal treatment.
- Conditions
- Diabetes Mellitus, Type 2, Type 2 Diabetes Mellitus, Periodontal Diseases, Periodontitis
- Trial name
- NCT02172716
- Testing
- Nonsurgical periodontal treatment
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Nasopharyngeal Carcinoma
A Retrospective Study Reveals the Relationship Between gp42-IgG Epitopes and EBV-associated NPC
Epstein-barr virus (EBV) infection is a necessary factor of nasopharyngeal carcinoma (NPC). The incidence of NPC in endemic regions reaches 24.60/100,000 people, far higher than that of the worldwide average.
- Trial name
- NCT05949749
- Testing
- Epitope exploration
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck
Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation
This clinical trial tests the impact of offering hearing tests (audiometry) close to home and remotely on participation in monitoring for treatment-related hearing loss in patients with head and neck squamous cell cancer…
- Conditions
- Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Cutaneous Squamous Cell Carcinoma of the Head and Neck, Head and Neck Carcinoma of Unknown Primary, Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT06662058
- Testing
- Audiometric Test, Interview
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Emory University
Recurrent Nasopharyngeal Carcinoma
A Clinical Trial of Chemotherapy With Lobaplatin and 5-FU in Recurrent Local or Distant Advanced NPC.
The purpose of this study is to evaluate the efficacy and safety of chemotherapy with Lobaplatin and 5-FU, in Recurrent Local or Distant Advanced Nasopharyngeal Carcinoma.
- Trial name
- NCT03210389
- Testing
- Lobaplatin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University
Bone Loss in Jaw
Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation
The purpose of this clinical trial is to assess if the addition of DFDBA fibers to DBBM results in greater vital bone formation than the addition of DFDBA particles to DBBM.
- Trial name
- NCT06173791
- Testing
- DFDBA fibers, DFDBA particles, DBBM
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Tongue Cancer, Squamous Cell Carcinoma
Surgical Margin Assessment by 3D Ultrasound
Complete removal of cancer encircled by a secure margin of healthy tissue is the aim of surgical oncology. A close or positive surgical margin reported by pathologist typically ends in adjuvant therapies (re-surgery and/or…
- Conditions
- Tongue Cancer, Squamous Cell Carcinoma, Head and Neck Cancer
- Trial name
- NCT05740774
- Testing
- 3D ultrasound
- Where
- Denmark
- Volunteers
- 7 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Dental Caries
Retention Rate And Caries Prevention Of Giomer Based Sealant With And Without Pre-Treatment With Bioactive Glass Air Abrasion In Young Adults
Prevention of oral diseases is preferable to treatment and is the key method of achieving cost effectiveness for oral health improvement programs.
- Trial name
- NCT06003452
- Testing
- surface treatment with Bioactive Glass Air Abrasion
- Where
- Egypt
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cairo University
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