Clinical trials: Stomatognathic Disease
Oral Cavity Squamous Cell Carcinoma
Study Comparing Limited and Extensive Neck Surgery in Oral Cancer Patients With Neck Spread
Oral cavity squamous cell carcinoma (OCSCC) frequently metastasizes to cervical lymph nodes, and the extent of neck dissection remains an area of ongoing debate in patients with clinically node-positive (cN1) disease.
- Trial name
- ExtentN1 (NCT07717307)
- Testing
- Selective Neck Dissection (Levels I-IV), Modified Neck Dissection (Levels I-V)
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Kolhapur Cancer Centre - Cancer Centers of America
Mucositis
Oral Zinc Therapy for the Prevention of Mucositis
Zinc is an intracellular mineral with important enzymatic cofactor activities for cell membrane stability, DNA and RNA structure. Zinc deficiency is associated with delayed wound healing and immune dysfunction.
- Trial name
- NCT00449592
- Testing
- Zinc
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Gastroesophageal Reflux, Pharyngeal Diseases
Study of Changes in Reflux Symptoms and Reflux Finding Score According to Rabeprazole Treatment Period
The purpose of this observational study is to examine RSI (Reflux Symptom Index) and RFS (Reflux Finding Score) by treatment period before and after rabeprazole treatment in LaryngoPharyngeal Reflux Disease(LPRD) patients.
- Trial name
- NCT00614536
- Testing
- Rabeprazole Sodium
- Volunteers
- 1,142 people
- Sponsor
- Janssen Korea, Ltd., Korea
Oral Mucositis, Quality of Life
Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
Effect of Live Combined Bifidobacterium,Lactobacillus and Enterococcus Capsules on Oral Mucositis in Nasopharyngeal Carcinoma Patients Receiving Radiotherapy.
- Trial name
- NCT03112837
- Testing
- Lactobacillus, Bifidobacterium and Enterococcus
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jiangxi Provincial Cancer Hospital
Malocclusion
Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
The purpose of this study is to examine the amount of tooth movement achieved over time between subjects undergoing aligner treatment using a pulsation device known as AcceleDent® Aura with those not using the device.
- Trial name
- NCT01962012
- Testing
- AcceleDent Aura
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- OrthoAccel Technologies Inc.
Temporomandibular Joint Disorders, Dizziness
Investigation of the Aural Symptoms and Dizziness in Patients With Temporomandibular Joint Disorders
120 male and female patients aged between 18-65 years who apply to the outpatient clinic and diagnosed with TMD will be included in the study.
- Conditions
- Temporomandibular Joint Disorders, Dizziness, Tinnitus
- Trial name
- NCT05402228
- Testing
- temporomandbular joint disorders
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Dental Implants, Tooth Loss
Immediate Load in Dental Implants Using Conventional Drilling and Piezoelectric Osteotomy on Aesthetic Zone.
Compare the survival rate of the implants placed using the ultrasonic technique and placed using conventional drilling, with an immediate load on the aesthetic zone.
- Trial name
- NCT04497571
- Testing
- Piezoelectric osteotomy., Conventional drilling
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of a hyaluronic acid-based gel, compared to MINSD…
- Trial name
- NCT05188898
- Testing
- MINSD and Hyaluronic acid, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Head and Neck Cancer, Oropharyngeal Carcinoma
Thermotherapy for Locally Advanced Head and Neck Cancer
Patients with head and neck cancer treated with radiotherapy (RT) have a substantial change of recurrence of the tumor in the pharynx or lymph nodes in the neck. Once tumor and/or lymph nodes have recurred, the prognosis is poor.
- Conditions
- Head and Neck Cancer, Oropharyngeal Carcinoma, Hypopharyngeal Carcinoma, Laryngeal Cancer
- Trial name
- TANCA-I (NCT06761937)
- Testing
- Thermotherapy, radiotherapy
- Where
- Netherlands
- Volunteers
- 2 people
- Sponsor
- Erasmus Medical Center
Periodontal Diseases, Sleep
Periodontitis, Sleep Quality and Fatigue
The goal of this observational study is to investigate the association of stage-grade of periodontitis with sleep quality and fatigue and the effect of periodontitis on QoL (Quality of life) in individuals with periodontitis and…
- Conditions
- Periodontal Diseases, Sleep, Fatigue, Quality of Life
- Trial name
- NCT05622019
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Fluid Loss, Symptom Complex, Triple
Saline vs. Lactated Ringers for Emergency Department IV Fluid Resuscitation
Administration of intravascular (IV) fluid is the most common emergency department (ED) procedure. IV fluids are integral to increasing effective blood volume and ensuring organ perfusion in patients with volume depletion and…
- Conditions
- Fluid Loss, Symptom Complex, Triple, Emergencies
- Trial name
- NCT03133767
- Testing
- Lactated Ringer Solution, Normal Saline 0.9% Infusion Solution Bag
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- Nicholas M Mohr
Dental Caries
Effectiveness of Fissure Sealant and Topical Fluoride Application in Preventing Dental Caries
Nearly half of the 12-year-old children in China have dental caries (tooth decay) and most of the lesions are in the fissures of the first permanent molars.
- Trial name
- NCT01446107
- Testing
- placement of fissure sealant, fluoride varnish, silver fluoride
- Where
- China
- Volunteers
- 502 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Dental Plaque
Oral Hygiene Related Self-efficacy, General Self-efficacy and Daily Plaque Control
The objectives are a) to determine the scores of general self-efficacy (GSE) and oral hygiene related self-efficacy (OHSE) b) to evaluate the relations between the scores of GSE and OHSE c) to examine the changes in OHSE scores…
- Trial name
- NCT03782311
- Testing
- motivation and and oral hygiene instructions
- Volunteers
- 52 people
- Sponsor
- Ege University
Periodontal Disease
Artificial Intelligence for Diagnosing Periodontitis and Monitoring Gingival Inflammation
Background and Objective: Periodontitis and gingivitis are highly prevalent oral diseases that require accurate diagnostic classification and continuous gingival health monitoring.
- Trial name
- NCT07629934
- Testing
- AI-driven Periodontal Diagnostic and Monitoring Algorithms
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Rheumatoid Arthritis, Psoriatic Arthritis
Role of Oral and Intestinal Microbiota in Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is an inflammatory form of arthritis that causes joint pain and damage. RA attacks the lining of the joints (synovium), causing swelling that can result in aching and throbbing, and eventually deformity.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Periodontal Disease
- Trial name
- NCT01198509
- Testing
- doxycycline, vancomycin
- Where
- 2 sites in United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Missing Teeth
Efficacy of a Dental Implant System for Immediate Restoration
The primary objective of this study is to observe the performance of an implant system with a new surface (EK III NH dental implants) over a period of two years.
- Trial name
- NCT06651502
- Testing
- dental implant placement and immediate provisionalization
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Periodontitis, Periodontitis Stage II
Comparative Effects of Two Oral Antiseptics Used as an Adjuvant in the Treatment of Periodontitis
The focus of this study is on two types of mouthwashes - one containing a chlorhexidine (CHX) at 0.2% (CHX), and the other one containing CHX at a lower concentration of 0.12% with cetylpyridinium chloride (CPC).
- Conditions
- Periodontitis, Periodontitis Stage II, Periodontitis Stage III
- Trial name
- NCT06967402
- Testing
- Experimental (chlorhexidine), Control (chlorhexidine with cetylpyridinium chloride)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oropharynx Cancer, Oral Cavity
Oncology, Undernutrition and Sensoriality: Links, Mechanisms and Levers for Action
Cancers of the upper aerodigestive tract account for around 4% of all malignant tumours worldwide. Colon and liver cancer are the most common digestive cancers.
- Conditions
- Oropharynx Cancer, Oral Cavity, Colon Cancer, Liver Cancer
- Trial name
- ONDES (NCT06600295)
- Testing
- tests/questionnaires, biological samples, evaluation
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Apexogenesis, Pulp Exposure, Dental
Bioceramic Repair Materials in Apexogenesis of Immature Permanent Molars
The present study was conducted to compare the clinical, radiographic, and tomographic outcomes of apexogenesis using Bio-C Repair and Biofactor MTA in immature permanent first molars with vital asymptomatic pulp exposure.
- Conditions
- Apexogenesis, Pulp Exposure, Dental, MTA Vital Tooth Pulpotomy, Cone Beam Computed Tomography
- Trial name
- NCT07883239
- Testing
- Bioceramic Repair Pulpotomy (BIO-C® REPAIR), Mineral Trioxide Aggregate Pulpotomy (Biofactor MTA)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.