Clinical trials: Stomatognathic Disease
Oral Cancer
Evaluation of a Multispectral Vision Enhancement System for Assessment of Oral Mucosal Lesions
To obtain data to evaluate whether multispectral digital imaging can assist clinicians to screen for premalignant lesions in the oral cavity.
- Trial name
- NCT00502580
- Testing
- Interview
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- M.D. Anderson Cancer Center
Cleft Lip and Palate
Weigh Easy: Simplifying Home Weight Monitoring for Infants
This single-site, experimental, pilot study in infants identified from 0 - 3 months of age who present to the Cleft and Craniofacial Clinic with a cleft lip and/or palate will compare weight outcomes of infants who used the Weigh…
- Trial name
- NCT04384276
- Testing
- The Weigh Easy System, Retrospective Control
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Gingivitis, Dental Plaque
Comparing the Efficacy of Toothbrushing With and Without Interproximal Cleaning Aids: A Split-Mouth Trial
The goal of this prospective clinical trial is to evaluate whether adding interproximal cleaning aids (interproximal brush, rubber toothpick, water flosser) to regular tooth brushing improves oral hygiene outcomes and gingival…
- Conditions
- Gingivitis, Dental Plaque, Periodontal Disease
- Trial name
- NCT07725276
- Testing
- Tooth Brushing Alone (Control), Water flosser, Interproximal Brush
- Where
- Lebanon
- Volunteers
- 29 people
- Sponsor
- Saint-Joseph University
Dental Caries
DPBRN Reasons for Replacement or Repair of Dental Restorations
The purpose of this study was to document the reasons for replacement or repair of defective restorations ("fillings") and to record the restorative material of the failed restoration and the material used in the replacement…
- Trial name
- NCT01201876
- Where
- 7 sites in United States, Denmark
- Volunteers
- 6,368 people, healthy volunteers welcome
- Sponsor
- Dental Practice-Based Research Network
Dental White Spots
Enamel Damages Following De-bracketing From Infiltrated Surfaces
Demineralisation and white-spot caries often occures during MB treatment. While resin infiltration has been proved to stop progression of enamel demineralisation, there is still a paucity of information in the literature…
- Trial name
- NCT02359318
- Testing
- Resin infiltration, Bonding and debonding of brackets.
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Tooth Disease
Clinical Evaluation of a Restorative Glass Ionomer and a Composite Resin for the Restoration
The clinical performances of a restorative glass ionomer and a composite resin will be compared in the restoration of non-carious cervical lesions (NCCLs) at patients with systemic diseases.
- Trial name
- NCT04266210
- Testing
- Fuji Bulk, G-ænial Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Dental Implant, Edentulous Alveolar Ridge
Clinical and Radiographic Comparison of Two Implant-Abutment Connections
The aim of this clinical study is to evaluate two different implant-abutment connection design on preserves gingiva and bone health in the long term.
- Trial name
- NCT07889882
- Testing
- N1 Dental implant placement + N1 abutment, Nobel active Implant placement + on1 abutment
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kutahya Health Sciences University
Nasopharyngeal Carcinoma
Paclitaxel (Albumin-bound) Combined With Radiotherapy for the Treatment of Early Stage Nasopharyngeal Carcinoma
This trial is a prospective, parallel controlled, randomized, open, multi-center phase III clinical trial. The trial will enroll 364 patients with nasopharyngeal carcinoma who are staged T1-2N0-1M0 (except T1N0M0) (UICC 8th…
- Trial name
- NCT04766359
- Testing
- Albumin-Bound Paclitaxel
- Volunteers
- 364 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Dry Eye, Keratoconjunctivitis Sicca
Efficacy of Two Concentrations of Autologous Serum for the Treatment of Severe Dry Eye
The purpose of this study is to compare the effects of autologous serum 20% and autologous serum 50% for the treatment of Severe Dry Eye Syndrome
- Conditions
- Dry Eye, Keratoconjunctivitis Sicca, Sjogren's Syndrome, Corneal Diseases
- Trial name
- NCT03436576
- Testing
- Autologous Serum 20%, Autologous Serum 50%
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Streptococcal Pharyngitis
Diagnostic Accuracy of Rapid Molecular Tests for Group A Streptococcal Pharyngitis Using Saliva Samples
Observational study evaluating the diagnostic accuracy of rapid point-of-care molecular Group A strep diagnostic tests in saliva as compared to standard culture- and PCR-based techniques for the management of children aged 3-15…
- Trial name
- NCT05521568
- Testing
- Index test: Abbott ID NOW STREP A 2, Reference standard test: Composite of culture and PCR-based tests based on a throat swab, Comparator test: Rapid antigen detection test (usual care)
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Head and Neck Squamous Cell Carcinoma, Malignant Head and Neck Tumors
A Lithium-containing Mouthwash Prevention and Treatment of Oral Mucositis and Dysgeusia in Patients Undergoing Radiotherapy
To evaluate the efficacy and safety of lithium-containing mouthwash for prevention and treatment of oral mucositis and dysgeusia in patients undergoing radiotherapy for malignant head and neck tumors.
- Trial name
- NCT06251050
- Testing
- lithium-containing mouthwash （Phase I）, Plcacebo mouthwash （Phase II）, lithium-containing mouthwash（Phase II）
- Where
- China
- Volunteers
- 175 people
- Sponsor
- West China Hospital
Nasopharyngeal Carcinoma
Concurrent Chemoradiotherapy With Nimotuzumab for High Risk Nasopharyngeal Carcinoma
This is the first phase II randomized clinical trial of concurrent chemoradiotherapy with or without EGFR blocker Nimotuzumab for high risk advanced nasopharyngeal carcinoma(NPC) , determining whether concurrent…
- Trial name
- NCT04223024
- Testing
- CCRT+Nimotuzumab, CCRT alone
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Sun Yat-sen University
Periodontal Disease Stage 2, Peri-Implantitis and Peri-implant Mucositis
Evaluation of Hydrogel Application in the Treatment of Periodontitis and Peri-implantitis
To date, systemic/local antibiotics, antimicrobials, laser application, and probiotics have been used as adjuncts to improve the outcome of non-surgical periodontal treatment for both periodontitis and peri-implantitis patients.
- Conditions
- Periodontal Disease Stage 2, Peri-Implantitis and Peri-implant Mucositis, Periodontal Regeneration
- Trial name
- NCT06740123
- Testing
- Nonsurgical periodontal treatment and application of H42® hydrogel to the peri-implant pocket, Nonsurgical periodontal treatment of periodontal pocket, Non-surgical periodontal treatment and application of H42® hydrogel to the periodontal pocket
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Temporomandibular Disorders (TMD), Orofacial Pain
Comparing the Effectiveness of Online vs. Face-to-face Physiotherapy for Treating Temporomandibular Disorders
Dentists and physiotherapists have two options for treating these conditions: splint therapy and physiotherapy. Right now, the gold standard is individual physiotherapy, which contains manual therapy and active exercises too.
- Conditions
- Temporomandibular Disorders (TMD), Orofacial Pain, Temporo-mandibular Dysfunction, Temporomandibular Joint and Muscle Disorder
- Trial name
- NCT07474662
- Testing
- Individual physiotherapy, Group physiotherapy, Online physiotherapy
- Where
- 2 sites in Hungary
- Volunteers
- 90 people
- Sponsor
- Semmelweis University
Molar Incisor Hypomineralization
Molar-Incisor Hypomineralization and Resin Infiltration
This dual-design study-encompassing a cross-sectional descriptive phase and a controlled clinical trial-aims to investigate the prevalence and associated risk factors of Molar Incisor Hypomineralization (MIH), while evaluating…
- Trial name
- NCT07873268
- Testing
- Resin infiltration, Fluoride Varnishes
- Where
- 3 sites in Vietnam
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hanoi Medical University
Periodontitis
Prevalence of Periodontitis Based Upon Principles Presented by the 2017 Classification: A Hospital-based Cross-sectional Study on a Sample of Young Egyptian Dental Patients
The study aims at determining the Prevalence Of Periodontitis based upon principles presented by the 2017 Classification: A Hospital-Based Cross-Sectional Study on A Sample of Young Egyptian Dental Patients
- Trial name
- NCT05441397
- Where
- Egypt
- Volunteers
- 464 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malocclusion, Narrow Maxilla
Clear Orthodontic Expander Versus Hyrax
This study will be conducted to evaluate the effectiveness of a clear expander fabricated from 2-mm biocompatible polyethylene terephthalate glycol (PETG) thermoforming material integrated with an expansion screw in achieving…
- Trial name
- COE-Hyarx (NCT07362160)
- Testing
- New clear expander, Hyrax expander
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Gingival Recession
Xenogeneic Collagen Matrix or Palatal Connective Tissue Graft With a Coronally Advanced Flap in Class III Recessions
The purpose of this multi-center study is to compare the effectiveness of Mucograft versus connective tissue graft in combination with coronal advanced flap for the treatment of Miller class III recessions The connective tissue…
- Trial name
- NCT03344315
- Testing
- experimental: collagen matrix, Active Comparator: autologous connective tissue graft
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Basque Country (UPV/EHU)
Taste, Altered
Efficacy of Zinc on Concurrent Chemo-radiotherapy Induced Taste Alterations
Taste changes are common in cancer patients receiving concurrent chemoradiation which become a significant complaint and a cause of distress and morbidity.
- Trial name
- NCT03824925
- Testing
- Zinc Sulfate 220 MG
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Gingival Bleeding, Prosthesis Failure, Dental
Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel
This study aims to compare the horizontal gingival displacement by using a retraction cord and aluminum chloride gel, and also to determine the time taken for placement and hemorrhage after the procedure by using a retraction…
- Conditions
- Gingival Bleeding, Prosthesis Failure, Dental, Tissue Injury
- Trial name
- NCT07255976
- Testing
- knitted cotton retraction cord, aluminum chloride gel
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.