Clinical trials: Stomatognathic Diseases
Dystonia, Drug Induced Dystonia
Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
- Conditions
- Dystonia, Drug Induced Dystonia, Parkinson Disease, Essential Tremor
- Trial name
- NCT05317390
- Testing
- DystoniaNet-based diagnosis of isolated dystonia
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Chronic Periodontitis, Aggressive Periodontitis
Chronic Presence of Epstein Barr Virus in Epithelial Cells From Gingiva is Associated With Periodontitis
The etiopathogenesis of periodontal disease results from complex interaction between infectious agents, mainly including bacteria, and host cellular and humoral immune responses.
- Conditions
- Chronic Periodontitis, Aggressive Periodontitis, Presence / Absence of EBV
- Trial name
- NCT01246596
- Testing
- dental root planing
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Tonsil Disease, Tonsillitis
Intracapsular Tonsillectomy in Adults
Comparing the classical extracapsular tonsillectomy (TE) performed with electrosurgery to intracapsular approaches (SIPT) by coblation or microdebrider. The patient group is adults with recurrent or chronic tonsillitis
- Conditions
- Tonsil Disease, Tonsillitis, Tonsillitis Acute, Tonsillitis Chronic
- Trial name
- NCT03654742
- Testing
- tonsillectomy
- Where
- Finland
- Volunteers
- 167 people
- Sponsor
- Turku University Hospital
Dental Caries
Dental and Oral Finding in Israeli Children With Past Intrauterine Growth Retardation (IUGR)
oral status and early childhood caries (ecc) in israeli children with past IUGR
- Trial name
- NCT00867542
- Testing
- no intervention
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Dental Caries
Clinical Evaluation of Three Dental Adhesive Systems in Class V Restorations
The purpose of this study is to compare the clinical performance of three dental adhesive systems used to bond Class V cavity fillings in adult teeth.
- Trial name
- NCT00643461
- Testing
- Adhesive A, Adhesive B, Adhesive C
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Solventum US LLC
Temporomandibular Joint Disorders
The Effect of Body Awareness Therapy on Pain, Function and Psychosocial Parameters in Temporomandibular Joint Disorders
This randomized, single-blind controlled trial aims to investigate the effectiveness of Body Awareness Therapy (BAT) on pain, functional limitations, and psychosocial outcomes in individuals with temporomandibular joint disorders…
- Trial name
- BAT-TMJ (NCT07317570)
- Testing
- Body Awareness Therapy, Standard Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Deep Overbite
Tooth Borne Versus Temporary Anchorage Devices (TAD) Based Intrusion Systems for the Correction of Anterior Deep Overbite
Compare the tooth borne versus fixed orthodontic intrusive system (TADs) for the correction of anterior deep overbite
- Trial name
- NCT06430710
- Testing
- Intrusion
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Periodontitis, Adult, Periodontitis (Stage 3)
Microbiological and Clinical Effects of Pre- and Probiotics in Non-Surgical Periodontal Therapy
Periodontitis is a prevalent chronic inflammatory disease driven by a dysbiotic oral biofilm and a dysregulated host immune response.
- Conditions
- Periodontitis, Adult, Periodontitis (Stage 3), Periodontitis Stage IV
- Trial name
- PROPARO (NCT07443410)
- Testing
- Non-surgical periodontal therapy (NSPT) and supportive periodontal therapy (SPT), Probiotic lozenge (Limosilactobacillus reuteri; GUM® PerioBalance®), Vitamin B12 drops (natural elements)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Dental Implant, Peri-Implantitis
Alveolar Ridge Sequelae Due to Peri-implantitis: a Retrospective Observational Study
The scientific evidence available at present regarding the alterations suffered by the alveolar ridge after the explantation of implants that have been considered to be abandoned due to periimplantitis, as well as the remaining…
- Conditions
- Dental Implant, Peri-Implantitis, Bone Remodeling
- Trial name
- NCT04534361
- Testing
- CBCT measurements
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Mandibular Deficiency
Mandibular Reconstruction With Axially Vascularised Bone Substitutes
Mandibular reconstruction is necessary following trauma, tumour resections and extensive infections resulting in severe defects of the mandibular arch.
- Trial name
- NCT04001842
- Testing
- Surgical reconstruction of the mandible using an axially vascularized bone construct
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- University of Alexandria
Canker Sore
Salivary Catecholamines in Aphthous Stomatitis (Canker Sores)
The purpose of this study is to examine how compounds produced in patients with canker sores affect wound healing.
- Trial name
- NCT00556686
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Davis
Gingivitis
To Compare the Effectiveness of Three Self-care Oral Hygiene Regimens
The study is designed to evaluate the clinical changes in gingival health by measuring the reduction of gingival bleeding and inflammation over 4 weeks.
- Trial name
- NCT04804670
- Testing
- Power device A, Power device B, Routine Oral Hygiene
- Where
- Canada
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Water Pik, Inc.
Dental Caries
The Anticariogenic Effect of Miswak (Silvadora Persica) and Grape Seed Extract
Prevention of dental caries has taken a great importance in the last decade. The use of herbal and natural products became mandatory to avoid the side effects of commercially available medications.
- Trial name
- NCT04136639
- Testing
- Miswak, Grape Seed Extract Mouthwash, fluoride
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Discoloration
Phycosocial Impact of Bleaching Teeth
58 patients between 18 and 76 years who attended the Operative Dentistry Clinic at Dental School, Universidad de Chile, were included in the study.
- Trial name
- PSYBLE (NCT02605239)
- Testing
- Bleaching teeth
- Where
- Chile
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Chile
Oral Cavity Cancer
A Study of High-Risk Oral Cavity Cancer
Objectives: 1. To study the effect of anti-angiogenesis therapy on reducing the recurrence of high-risk oral cavity cancer patients after curative local treatment. 2.
- Trial name
- NCT00934739
- Testing
- Thalidomide, Celebrex, Cyclophosphamide, Dexamethasone
- Volunteers
- 150 people
- Sponsor
- National Health Research Institutes, Taiwan
Periodontal Diseases, Biomarkers (D23.050.301)
AI-Assisted Saliva Diagnostics Using an Electrochemical Sensor Platform for Periodontitis Detection (SALIENCE)
This observational study aims to develop and validate a novel, AI-assisted electrochemical sensor platform for saliva-based diagnostics in periodontitis.
- Conditions
- Periodontal Diseases, Biomarkers (D23.050.301), Diagnostic, Saliva
- Trial name
- SALIENCE (NCT07254039)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ostergotland County Council, Sweden
Postoperative Sore Throat
Effect of Chewing Gum and Mouthwash Before Operation on Sore Throat After General Anesthesia With a Laryngeal Mask
Postoperative sore throat (POST) is an important problem after general anaesthesia. We assessed whether chewing gum preoperatively or mouthwash can reduce the incidence of POST after general anaesthesia administered via a…
- Trial name
- NCT04644900
- Testing
- chewed mint gum, Mouthwash
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Fudan University
Molar-Incisor Hypomineralization (MIH)
Nano Silver Fluoride and Photobiomodulation Therapy for Hypersensitivity and Pain in MIH-Affected Molars
Molar-incisor hypomineralization (MIH) is a developmental condition affecting primarily the first permanent molars and may be associated with post-eruptive enamel breakdown, hypersensitivity, and difficulties in achieving…
- Trial name
- NCT07826130
- Testing
- Nano Silver Fluoride, Photobiomodulation Therapy, Pre-appointment analgesics
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Gastroesophageal Reflux Disease, Tooth Wear
Relationship Between Gastroesophageal Reflux Disease and Dental Erosion
This study aimed to investigate the relationship between gastroesophageal reflux disease (GERD) and dental erosion and the alterations in oral tissues. This was a case-control study.
- Trial name
- NCT04595500
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Dental Plaque
Livionex Oral Microbiome and Dental Plaque Control in HSCT Recipients
Children undergoing chemotherapy, radiation treatment and Hematopoietic Stem Cell Transplantation (HSCT) have significant difficulties achieving good oral hygiene and dental plaque control.
- Trial name
- NCT02617407
- Testing
- Livionex® Dental Gel, PreviDent 5000 plus/Tom's of Maine Children's toothpaste, Kolibree Toothbrush
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Francisco
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