Clinical trials: Stomatognathic Diseases
Gingival Recessions
Influence of Keratinized Tissue Width and Attached Gingiva Width on Root Coverage in Patients With Recession Defects: A Prospective Clinical Study
To evaluate the association between the width of keratinized tissue and attached gingiva with root coverage outcomes in RT1 gingival recession defects of maxillary and mandibular anterior teeth treated with subepithelial…
- Trial name
- NCT07576439
- Testing
- Vestibular incision subperiosteal tunnel access with connective tissue graft in treating RT 1 gingival recession defects
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Styloid-Stylohoid Syndrome, Temporomandibular Disorder
Evaluation of Styloid Chain Calcification to the Patient With the Temporomandibular Joint Disorder
The aim of the study was to evaluate any relation between elongated styloid process (ESP) and type of Temporomandibular Joint Disorders (TMD).
- Trial name
- NCT04280107
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Nuh Naci Yazgan University
Tooth Erosion
Investigate a Varnish to Protect From Erosive Toothwear
This in-situ study will investigate on extracted teeth the protection of a re-formulated varnish containing fluoride in the same concentration as an existing approved varnish used to treat caries and erosion.
- Trial name
- NCT06136754
- Testing
- Varnishes, Fluoride
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Loss, Disorder Related to Renal Transplantation
Osseointegrated Dental Implants in Kidney Transplanted Patients
The evaluation of the bone, using several techniques and on several aspects will be the purpose to study the possible impact of the kidney transplant (and, extensively, the pre-transplant dialysis, the organ replacement and the…
- Trial name
- NCT02513602
- Testing
- Dental implant insertion
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- University of Trieste
Periodontal Diseases, Dental Plaque
Marginal Biofilm Distribution and Periodontal Response to Supragingival and Juxtagingival Aligner Designs
This prospective, longitudinal, within-person (split-mouth) clinical study evaluates the influence of two clear aligner trimming-line designs on marginal soft-tissue biofilm distribution and periodontal tissue response over a…
- Conditions
- Periodontal Diseases, Dental Plaque, Gingivitis
- Trial name
- BIOFILM-ALIGN (NCT07642037)
- Testing
- Supragingival aligner trimming-line, Juxtagingival festooned aligner trimming-line
- Where
- Romania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Endodontically Treated Teeth
Bite Force and Occlusal Force Distribution Following Root Canal Treatment.
Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the…
- Trial name
- B-FORCE RCT (NCT07626372)
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Gingival Inflammation
Lactobacillus Reuteri Strains for Gingivitis Reduction
The aim of the present study was to investigate the potential beneficial effects in volunteer young adults of orally administered L. reuteri (DSM 17938 and ATCC PTA 5289) on gingival inflammation.
- Trial name
- NCT06234839
- Testing
- L. reuteri (DSM 17938 and ATCC PTA 5289) in form of oral tablets
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Mandible Cyst, Mandible Tumor
Bone Lid Technique Versus Standard Technique for Treatment of Mandibular Lesions
Twenty patients with benign mandibular lesion will be included in this study. the patient will be divided randomly (10 patients each group). Group I the lesion will be treated using bone lid technique.
- Conditions
- Mandible Cyst, Mandible Tumor, Mandibular Diseases
- Trial name
- NCT05987930
- Testing
- bone lid technique, standard technique
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tanta University
Platelet-rich Fibrin, Sinus Floor Augmentation
Maxillary Sinus Augmentation With Xenogeneic Bone Graft Associated or Not With Fibrin Rich in Platelets and Leukocytes Produced by Horizontal Centrifugation: A Randomized Clinical Trial.
The objective of study is to evaluate the influence of the use of Platelet Rich Fibrin (PRF) from the patient's produced by a new horizontal centrifugation protocol associated with particulate xenogenous bone graft in the…
- Conditions
- Platelet-rich Fibrin, Sinus Floor Augmentation, Cone-beam Computed Tomography, Dental Implants
- Trial name
- NCT05957705
- Testing
- Maxilar Sinus augmentation, Dental implant placement using guided surgery
- Where
- Brazil
- Volunteers
- 13 people
- Sponsor
- University of Sao Paulo
Gingival Recession
Treatment of Multiple Gingival Recessions With a MCAF or a MCAT and a Collagen Matrix
In a recent meta-analysis, Graziani et al. reported that despite the "ideal" treatment for multiple gingival recession defects is not yet identified, there are some indirect suggestions from the analyzed data that, in comparison…
- Trial name
- NCT04225351
- Testing
- MCAF+CM, MCAT+CM
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Edentulous Jaw
Study of Hard and Soft Tissue Behavior Around Abutments on Implants.
Purpose: To compare the loss of peri-implant tissue by means of radiographic and digital analysis of a zirconia prosthesis placed immediately and delay loading.
- Trial name
- NCT05924451
- Testing
- Immediate Loading
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universitat Internacional de Catalunya
Burning Mouth Syndrome
Inflammatory Markers in Saliva of Patients With Burning Mouth Syndrome
Burning Mouth Syndrome (BMS) is a chronic pain disorder that presents with inflammation and burning sensation in the oral cavity without visible lesions.
- Trial name
- burningmouth (NCT06217731)
- Testing
- Laser+clonazepam, Laser, Clonazepam
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Murcia
Dental Implant Failed, Teeth Absent
Gelatin Sponge VS PTFE Membrane for Socket Sealing After Immediate Implant Placement
Digital panoramas will be made to assess the implant sites. The included patients are assigned to their respective groups randomly.
- Conditions
- Dental Implant Failed, Teeth Absent, Soft Tissue Injuries
- Trial name
- NCT05982353
- Testing
- PTFE application, Gelatin sponge
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carcinoma, Squamous Cell, Oral Cancer
Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma
Participants in this study have a type of cancer called squamous cell carcinoma of the head and neck (SCCHN). Their SCCHN has spread around the area where the cancer first started. This is called locally-advanced SCCHN.
- Conditions
- Carcinoma, Squamous Cell, Oral Cancer, Oropharynx Cancer, Larynx Cancer
- Trial name
- NCT03174275
- Testing
- Durvalumab, Carboplatin, Nab-paclitaxel
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Chronic Generalized Periodontitis
Moxifloxacin in Situ Gel to Treat Periodontal Pocket.
In this Randomized clinical trial locally delivered moxifloxacin in situ gel was evaluated as an adjunct to scaling and root planing for efficacy in the treatment of chronic periodontitis and for short-term effects on the…
- Trial name
- NCT02016157
- Testing
- Moxifloxacin
- Where
- India
- Volunteers
- 5 people
- Sponsor
- Sri Hasanamba Dental College and Hospital
Healthy, Periodontitis
Effect of Non-Surgical Periodontal Treatment on Biomarker Levels
Periodontitis is a destructive disease that follows untreated gingivitis and is characterized by gingival inflammation, clinical attachment loss, alveolar bone loss and periodontal pocket formation, increased tooth mobility and…
- Trial name
- NCT06178081
- Testing
- Periodontal Healthy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Biruni University
Sjogren's Syndrome, Autoimmune Diseases
Exploratory Study of the Efficacy of HuMoSCs (Human Monocyte-derived Suppressor Cells) on Glandular Involvement in Sjögren's Syndrome
Sjögren's syndrome is an autoimmune disease. Dry syndrome is a key feature of this condition, almost always leading to dryness of the mouth and eyes.
- Trial name
- Immuno-DRYve (NCT07861828)
- Testing
- Blood sample, Salivary gland biopsy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Periodontal Disease
Estimation of Sialic Acid and IL10 Levels in Stage 1 and 2 Periodontitis Patients
Sialic acid (SA) is the generic term given to a family of acetylated derivatives of neuraminic acid. SA is a 9 carbon monosaccharide. An important function of host SA is to regulate innate immunity.
- Trial name
- NCT03775967
- Testing
- sialic acid, IL10
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ajman University
Gingival Recession
Evaluation of Two Types of Matrix (Mucograft® and Mucoderm®) Associated With Coronally Advanced Flap
The aim of this study is to evaluate clinically the results of two types of matrix (Geistlich Mucograft® and Mucoderm®) associated with CAF technique for the treatment of gingival recessions.
- Trial name
- NCT03667105
- Testing
- CAF, MC, XDM
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Dentofacial Deformities
Full-3D Computer-Assisted Workflow for the Diagnosis and Correction of Deformities? Dentofacial
"Dentofacial deformity refers to deviations from the norm of facial proportions and tooth ratios of such magnitude as to represent a disability." [1] These conditions afflicted two aspects of the patient's health: the first…
- Trial name
- NCT06806605
- Testing
- 3d analisys
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
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