Clinical trials: Stomatognathic Diseases
Ear Noise, Tinnitus, Noise Induced
Multimodal Therapy for Somatosensory Tinnitus
Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of the adult population and significantly reduces quality of life in many patients.
- Conditions
- Ear Noise, Tinnitus, Noise Induced, Tinnitus, Subjective, Headache Other
- Trial name
- SOMATIN (NCT07468318)
- Testing
- Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Nasopharyngeal Carcinoma
A Phase III Study of YL201 in Recurrent or Metastatic Nasopharyngeal Carcinoma (TAISHAN-301)
This study was designed to compare the efficacy and safety of YL201 with Investigator's choice of chemotherapy in subjects with recurrent or metastatic nasopharyngeal carcinoma who have failed prior PD-(L)1 inhibitor and at least…
- Trial name
- NCT06629597
- Testing
- YL201, Docetaxel, Capecitabine
- Where
- China
- Volunteers
- 400 people
- Sponsor
- MediLink Therapeutics (Suzhou) Co., Ltd.
Periodontitis, Chronic
Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction
Treatment of chronic medium-severe periodontitis with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
- Trial name
- NCT04446897
- Testing
- mesenchymal stem cells, standard treatment
- Where
- Belarus
- Volunteers
- 10 people
- Sponsor
- Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Biological Markers; Dental Implants; Cytokines; Triclosan; Toothpastes; Peri-Implantitis; Microbiology
Impact of a Triclosan-containing Toothpaste During the Progression of Experimental Peri-implant Mucositis
The aim of this study was to evaluate the influence of a triclosan-containing toothpaste in the profile of osteo-immunoinflammatory mediators in the peri-implant crevicular fluid (PICF) and in the clinical parameters during the…
- Trial name
- NCT03145610
- Testing
- triclosan/copolymer/fluoride toothpaste
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Paulista University
Periodontitis
Diagnostic Potential of the Salivary Biomarkers to Differentiate Statuses of Periodontitis
Periodontitis is a chronic inflammatory disease characterized by both dysbiosis of oral microbiota and proinflammatory events involving both cells and mediators from innate and adaptive immunity.
- Trial name
- NCT05722613
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontitis
Salivary Bacterial Profiles in Relation to Periodontal Treatment
The purpose of the present investigation is to record and compare bacterial compositions in subgingival plaque samples and saliva samples in subjects receiving periodontal treatment.
- Trial name
- NCT02913248
- Testing
- Conventional periodontal treatment
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- University of Copenhagen
Nasopharyngeal Cancer
A Study of Xeloda (Capecitabine) in Combination With XELOX (Oxaliplatin) in Patients With Metastatic Nasopharyngeal Cancer.
This single arm study will assess the efficacy and safety of Xeloda + oxaliplatin when given as first line treatment for patients with metastatic nasopharyngeal cancer.
- Trial name
- NCT00439426
- Testing
- Oxaliplatin, capecitabine [Xeloda]
- Where
- 5 sites in Morocco
- Volunteers
- 25 people
- Sponsor
- Hoffmann-La Roche
Oropharyngeal Cancer, Squamous Cell Carcinoma to the Head and Neck
A Pilot Study at a Single-Institution of Pregabalin in the Management of Mucositis Pain in Patients Undergoing Chemoradiation Therapy to the Head and Neck.
To assess the efficacy of pregabalin in the management of mucositis pain in patients receiving radiotherapy to the head and neck.
- Trial name
- NCT02277548
- Testing
- Lyrica 300 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Periodontitis
AI-Based Radiographic Detection of Periodontal Defects
The primary objective of the study is to develop and validate a machine learning model for the automatic identification of periodontal vertical bone defects, improving diagnostic accuracy and efficiency.
- Trial name
- NCT07086625
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Cagliari
Head and Neck Cancer, Non-melanomatous Skin Cancer
Radiation Therapy in Treating Patients With Head and Neck Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known which regimen of radiation therapy is more effective for head and neck cancer.
- Trial name
- NCT00021125
- Testing
- adjuvant therapy, radiation therapy
- Where
- United Kingdom
- Volunteers
- 460 people
- Sponsor
- Medical Research Council
Gingival Recession, Localized
The Laterally Closed Tunnel Versus Modified Coronally Advanced Tunnel for Mandibular Anterior Gingival Recession Defects
The aim of this study is to comparatively evaluate the advantages of LCT with SCTG over MCAT with SCTG for coverage of deep isolated mandibular anterior recession.
- Trial name
- NCT04198376
- Testing
- Group A The Laterally Closed Tunnel Technique with SCTG, Group B Modified Coronally Advanced Tunnel Technique with SCTG.
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Amelogenesis Imperfecta, Dental Fluoroses
Colorimetric, Ultra-structural and Elemental Comparison of Dental Enamel Defects
The study focuses on the analysis of enamel defects grouping together hypomineralization and hypoplasia. It focuses on 3 very characteristic enamel pathologies that are most often encountered in dental consultations: Molar…
- Conditions
- Amelogenesis Imperfecta, Dental Fluoroses, Hypomineralization Molar Incisor
- Trial name
- COLOEMAIL (NCT04704089)
- Testing
- spectrophotometer, Biological (protein analysis by western blot or mass spectrometry of matrix proteins), structural (electron microscopy) and physico-chemical analyses
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oral Disorder
Assessment and Remediation of Oral Disorders
As part of the Reference Center for Rare Diseases of the Robert Debré Hospital, many children have eating and verbal oral disorders.
- Trial name
- ERTO (NCT06046768)
- Testing
- Psychological care
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Temporomandibular Disorder, Fibromyalgia
Effects of a Self-management Program for Temporomandibular Myalgia in Subjects With Fibromyalgia: a Single Arm Study
Fibromyalgia is one of the most prevalent chronic widespread pain entities today. One of the most common problems in patients with fibromyalgia are alterations of the temporomandibular region, present in approximately 80% of the…
- Conditions
- Temporomandibular Disorder, Fibromyalgia, Self Management
- Trial name
- NCT05426655
- Testing
- Self management
- Where
- Spain
- Volunteers
- 107 people
- Sponsor
- Jose Edgar Ferrandez Gomez
Pulpitis
Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as…
- Trial name
- NCT06468085
- Testing
- premixed Bioceramic NeoPUTTY®, Biodentine™, Root canal treatment
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis, Adult
Association of Periodontitis With Oral Health Related Quality of Life
Objective: The aim of this study was to investigate the impact of periodontitis on oral health-related quality of life (OHQoL) and the factors may associated with OHQoL.
- Trial name
- NCT04240015
- Testing
- Oral-Dental Health-Related Quality of Life-United Kingdom (OHRQoL-UK) scale
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pulp Necroses
Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems
Evaluation of post operative pain after pulpectomy procedures for primary molars with irreversible pulp damage and without periapical radulicency using two different systems (One shape file ( ratation movemont) and wave one gold…
- Trial name
- NCT05057325
- Testing
- Pulpectomy using single file system ( One Shape file), Pulpectomy using single file system ( WaveOne Gold file)
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Minia University
Cerebral Palsy, Temporomandibular Disorder (TMD)
TMJ Dysfunction and Motor Severity in Children With CP
This study aims to examine the function of the temporomandibular joint (TMJ)-the jaw joint-in children with cerebral palsy (CP).
- Trial name
- NCT07043517
- Testing
- RDC/TMD
- Where
- Turkey (Türkiye)
- Volunteers
- 517 people
- Sponsor
- Istanbul Arel University
Bell Palsy
Motor Imagery and Mirror Therapy on Synkinesis, Facial Asymmetry, Facial Function and QoF in Bell's Palsy Patients.
Bell's palsy is a condition that causes sudden weakness in the muscles on one side of the face. The weakness makes half of the face appear to droop, difficulty in closing eyes and synkinesis.
- Trial name
- NCT06775717
- Testing
- Motor Imagery with conventional Treatment, Mirror therapy with conventional Treatment.
- Where
- 2 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Periodontal Pocket
The Use of Erythritol Powder and Metronidazole Gel for the Non-surgical Treatment of Periodontitis
Aim of the present study is evaluate the use of erythritol powder with/without the adjunct of local metronidazole in the treatment of periodontal pockets.
- Trial name
- NCT02023840
- Testing
- metronidazole gel, ultrasonics, erythritol
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Proed, Torino, Italy
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