Clinical trials: Stomatognathic Diseases
Tonsil Disease, Dental Diseases
Oral Device Clinical Trial
The investigators are studying the use of a new medical device developed at Nationwide Children's. This technology has been licensed and produced by Zotarix LLC, a medical device company.
- Conditions
- Tonsil Disease, Dental Diseases, Adenoid; Disorder (and Tonsils)
- Trial name
- NCT05022368
- Testing
- LabraGuard
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Nationwide Children's Hospital
Mastication Disorder
Masticatory Efficiency in Children
This study aims to evaluate the association of masticatory efficiency with different conditions of the stomatognathic system (transitioning from primary to secondary dentition, dental caries, malocclusion, tooth loss…
- Trial name
- NCT05000385
- Testing
- Assesment of masticatory efficiency with optical scanning method, body mass index
- Where
- 2 sites in Croatia
- Volunteers
- 96 people
- Sponsor
- Clinical Hospital Center Rijeka
Dental Diseases, Tooth Discoloration
6-year Clinical Performance of Prefabricated and Composite Veneers ( Componeer)
The aim of this study is to compare the clinical performance of composite veneers performed in two different ways, indirect and direct methods over a period of 6-year.
- Trial name
- NCT05998980
- Testing
- Componeer prefabricated veneers, Essentia resin composite veneers
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ege University
Dental Diseases, Tooth Discoloration
3-year Clinical Performance of Prefabricated and Composite Veneers
The aim of this study was to evaluate the clinical performances of Edelweiss prefabricated veneers and direct resin composite restorations (Ceram-X Duo SphereTec) performed with U- veneer transparent templates used for anterior…
- Trial name
- Edelweiss (NCT05984472)
- Testing
- Edelweiss prefabricated veneers, Ceram-X Duo SphereTec with U-Veneer
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ege University
Tooth, Impacted, Tooth Diseases
Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
This is a single centre, three-arm randomised, double-blind, double-dummy, parallel group, single-dose, active and placebo-controlled efficacy and pharmacokinetics/ pharmacodynamics study to evaluate the efficacy and safety of 2…
- Conditions
- Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT05484401
- Testing
- Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Tooth Loss, Bone Loss, Alveolar
Immediate Implant Outcomes With and Without Bone Augmentation
To evaluate immediate implant placement feasibility and esthetic outcomes in severely damaged sockets that received simultaneously bone reconstruction (cortical bone shield) and implant placement versus intact sockets that needed…
- Conditions
- Tooth Loss, Bone Loss, Alveolar, Dental Diseases, Dental Trauma
- Trial name
- NCT05157009
- Testing
- implant placement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Verdugo, Fernando, DDS
Dental Diseases
School Oral Health Intervention in Nepal
Oral health problems in school children are highly prevalent in Nepal. The investigators designed oral health counseling and promotion intervention in Kaski district of Nepal for six months.
- Trial name
- NCT05811650
- Testing
- Oral Health Counseling and promotion
- Where
- Nepal
- Volunteers
- 669 people, healthy volunteers welcome
- Sponsor
- Cyberjaya University College of Medical Sciences
Stroke, Mastication Disorder
Expiratory Muscle Training in Stroke
Stroke affects the vital activities of daily living such as breathing and swallowing. After stroke excursion of the diaphragm reduces about 50%, and also the maximum expiratory pressure of the individual 50% or higher.
- Conditions
- Stroke, Mastication Disorder, Temporomandibular Disorders, Dysphagia
- Trial name
- NCT04569968
- Testing
- Expiratory muscle training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Abant Izzet Baysal University
Molar Incisor Hypomineralization, Oral Health
Prevalence, Etiology and Effects on Oral Health and Life Quality of Molar Incisor Hypomineralization
Molar incisor hypomineralization (MIH) can lead to many clinical conditions and affect oral health-related quality of life (OHRQoL).
- Conditions
- Molar Incisor Hypomineralization, Oral Health, Child, Only, Pediatric ALL
- Trial name
- NCT05779332
- Testing
- survey application
- Where
- Turkey (Türkiye)
- Volunteers
- 655 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Dental Diseases
Clinical Evaluation of Dimethyl Sulfoxide Dentin Pre-treatment
This study is conducted in order to evaluate the clinical effectiveness of 1% DMSO dentin pre-treatment on the clinical performance of etch and rinse adhesive.
- Trial name
- NCT04492306
- Testing
- Dimethyl Sulfoxide, 3M ESPE Single bond 2, Filtek Z350 XT, 3 M ESPE, St Paul, MN, USA)
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Sjögren Syndrome
A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome
This was an adaptive design phase 2 study to establish safety and efficacy; and to characterize the dose-response of LOU064 in subjects with moderate to severe Sjögren's syndrome.
- Trial name
- LOUiSSe (NCT04035668)
- Testing
- Remibrutinib
- Where
- 26 sites in United States, Australia and 10 more
- Volunteers
- 73 people
- Sponsor
- Novartis Pharmaceuticals
Dental Diseases
Repair of Proximal Restoration Resin Bulk Fill. Clinical Trial
Bulk Fill" (RBF) composite resins (RC) has been on the market, with the main advantage of being applied in a single layer, faster and easier than a conventional RC.
- Trial name
- NCT05013866
- Testing
- Repair resin composite proximal
- Where
- Chile
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Andres Bello
Dental Diseases
A Clinical Trial to Evaluate the Safety and Effectiveness of MatrixOssTM Bone Graft
The objective of this clinical trial is to evaluate the efficacy and safety of MatrixOssTM Bone Graft in bone defect repair caused by tooth extraction.
- Trial name
- NCT05371535
- Testing
- MatrixOssTM Bone Graft plus Bio-Gide membrane
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Collagen Matrix
Hereditary Hemorrhagic Telangiectasia, Dental Diseases
Nationwide Awareness Campaign and Call for Dental Screening for HHT in Germany
HHT is a relative rare autosomal dominant inherited disorder of the fibrovascular tissue. Diagnosis of HHT is often delayed for decades (Pierucci 2012).
- Trial name
- NCT03549949
- Where
- Germany
- Volunteers
- 411 people, healthy volunteers welcome
- Sponsor
- University Hospital, Essen
Bone Resorption, Dental Diseases
Allogeneic Bone Paste Versus Allogeneic Bone Powder
Autogenous bone graft has been considered the gold standard in Guided Bone Regeneration (GBR) technique used for bone augmentation.
- Trial name
- NCT04141215
- Testing
- BIOBank bone paste, BIOBank cortico-cancellous bone powder
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Biobank
Periapical Periodontitis, Tooth Diseases
Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF
This study evaluates the clinical effect of regenerative endodontic procedure using PRF in immature permanent teeth with apical periodontitis.
- Conditions
- Periapical Periodontitis, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT02801552
- Testing
- PRF
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Pain, Stomatognathic Diseases
The Effect of Different Physiotherapeutic Stimuli on Stomatognathic System Structures.
The study will determinate influence of four selected physiotherapeutic procedures on the pain intensity and the range of mandibular mobility in patients with myofascial disorders in the SS.
- Conditions
- Pain, Stomatognathic Diseases, Muscle Hypertonia, Myofacial Pain Syndromes
- Trial name
- NCT05021874
- Testing
- Four different physiotherapy treatment
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Mouth and Tooth Diseases, Periodontal Diseases
Chlorhexidine and Essential Oil Mouthwashes on Human Beta-Defensin 2 (hbD2) and Kathelicidin (LL-37) Saliva Levels
Recent studies have shown that while mouthwashes exhibit antimicrobial properties against bacteria and their products, at the same time showing the cytotoxic effect on living cells in the mouth.29 To the best of our knowledge…
- Conditions
- Mouth and Tooth Diseases, Periodontal Diseases, Gingivitis
- Trial name
- hbD2 (NCT04946617)
- Testing
- undefined
- Volunteers
- 120 people
- Sponsor
- Istanbul Medeniyet University
Radiography, Digital
Deep Learning to Summarize Findings in Dental Panoramic Radiographs
In this work, the investigators study the application of artificial intelligence systems on dental panoramic images for dental findings.
- Conditions
- Radiography, Digital, Dental Diseases, Dentist-Patient Relations
- Trial name
- NCT04894201
- Testing
- Dental Panoramic Radiographs
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Dental Caries in Children, Dental Diseases
Information and Communication Technologies (ICTS) in Dentistry for SUS
At the time of the COVID-19 pandemic, thousands of children had their dental care interrupted or postponed, generating a pent-up demand for primary care.
- Trial name
- NCT04798599
- Testing
- Telemonitoring and teleorientation, Control Group - Waiting list
- Where
- Brazil
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo