Clinical trials: Stomatognathic Diseases
Sloughing Skin, Mucosal Inflammation
A Study to Assess the Impact of a Non-SLS Toothpaste Upon Oral Mucosal Desquamation
This study is to compare the effect on oral mucosal desquamation of a non-SLS toothpaste and an SLS-containing toothpaste..
- Trial name
- NCT03598881
- Testing
- Treatment
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Temporomandibular Disorder
A Comparison of Collagen, Lidocaine and Saline, in Trigger Points in Masseter Muscle.
An intramusclular injection of three solutions were performed( collagen, lidocaine, saline) in musculoskeletal trigger points, in patients suffering from temporomandibular disorders(TMD).
- Trial name
- NCT03323567
- Testing
- MD Muscle GUNA collagen, Lidocaine 2% Injectable Solution, Saline Solution, Hypertonic
- Where
- Poland
- Volunteers
- 43 people
- Sponsor
- Medical University of Silesia
Peri-implant Mucositis, Peri-Implantitis
Peri-implant Disease and Prosthetic Cement: Cross-sectional Study
The main objective of the present clinical study project, of a cross-sectional observational nature, is to evaluate the presence of submucosal cement residues through endoscopic visualization in clinical situations with…
- Trial name
- NCT05945836
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Bologna
Locally Advanced Salivary Gland Carcinoma, Metastatic Salivary Gland Carcinoma
Testing the Anti-cancer Drug Darolutamide in Patients With Testosterone-Driven Salivary Gland Cancers
This phase II trial tests how well darolutamide and leuprolide acetate work in treating patients with androgen receptor positive salivary cancer that has spread from where it first started (primary site) to other places in the…
- Conditions
- Locally Advanced Salivary Gland Carcinoma, Metastatic Salivary Gland Carcinoma, Recurrent Salivary Gland Carcinoma, Unresectable Salivary Gland Carcinoma
- Trial name
- NCT05669664
- Testing
- Biopsy Procedure, Biospecimen Collection, Computed Tomography
- Where
- 27 sites in United States
- Volunteers
- 21 people
- Sponsor
- National Cancer Institute (NCI)
Periodontal Disease
Towards a Viral Etiology of Periodontal Disease in Relation to Radiotherapy Treatment of Head and Neck Cancers
The treatment of otolaryngology (OLR) cancer is based on surgery, radiation, sometimes used in combination with chemotherapy. Patients treated with radiotherapy have multiple oral diseases: mucositis, hyposalivation, tissue…
- Trial name
- NCT02180932
- Testing
- periodontal pocket samples
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Palatal Wound
Comparison of Two Different Low-level Laser Intensity Protocols on the Healing of Palatal Wounds
The aim of this study was to compare two intensities of LLLT on wound healing process of the donor palatine area after CTG removal.
- Trial name
- NCT02580357
- Testing
- Low Level Laser Therapy, GaAlAs laser
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Diet Habit, Rheumatologic Disease
Rheumatology Diet Study
This study aims to collect information on rheumatology patients' dietary habits, autoimmune disease activity, dietary changes, disease symptom improvements, and perceptions on their dietary habits and how it affects their…
- Conditions
- Diet Habit, Rheumatologic Disease, Autoimmune Diseases, Rheumatoid Arthritis
- Trial name
- NCT06339957
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Central Florida
Irreversible Pulpitis (Toothache)
Comparative Evaluation of Intraligamentary Injection of Dexamethasone, Diclofenac Sodium, and Chymotrypsin for Enhancing the Success of 4% Articaine Buccal Infiltration in Mandibular Molars With Symptomatic Irreversible Pulpitis
The goal of this clinical trial is to compare anesthetic success rates of intraligamentary dexamethasone, diclofenac sodium, and chymotrypsin administered prior to buccal 4% articaine infiltration in mandibular molars with…
- Trial name
- NCT07506265
- Testing
- Dexamathsone 4mg/ml associated with experimental arm, Diclofenac Sodium (DCS), chymotrypsin
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Fayoum University
Nasopharyngeal Carcinoma (NPC)
SSTR2 Imaging With [68Ga]Ga-DOTA-TOC PET/CT in NPC
This is an investigator-initiated, single-center clinical trial designed to evaluate the feasibility of [68Ga]Ga-DOTA-TOC positron emission tomography (PET) scan in patients with Epstein-Barr virus (EBV) related nasopharyngeal…
- Trial name
- NACASOR (NCT06982300)
- Testing
- [68Ga]Ga-DOTA-TOC PET imaging
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- University Medical Center Groningen
Oral Cancer, Oral Health Knowledge, Attitude and Practice Among Patients
mHealth App for Oral Hygiene and Cancer Awareness in Older Adults
The goal of this clinical trial is to learn whether a mobile app with educational videos and serious games is more effective than a video-only version of the app to improve knowledge, attitudes, and practices about oral cancer…
- Conditions
- Oral Cancer, Oral Health Knowledge, Attitude and Practice Among Patients, Older Adults
- Trial name
- NCT07275411
- Testing
- Mobile Oral Health Education App
- Where
- Chile
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Chile
Penile Cancer, Melanoma
Validation of ICG-99mTc-nanoscan as Hybrid Tracer for Sentinel Node Biopsy
99mTc-nanocolloid, the world wide used hybrid tracer for dynamic sentinel node biopsy, has recently been replaced with 99mTc-nanoscan.
- Conditions
- Penile Cancer, Melanoma, Oral Cancer
- Trial name
- NANOSCAN (NCT06666634)
- Testing
- Sentinel node biopsy with either ICG-99mTc-nanoscan or 99mTc-nanoscan
- Where
- Netherlands
- Volunteers
- 29 people
- Sponsor
- The Netherlands Cancer Institute
Sjogren's Syndrome
Olfactory and Taste Disturbances in Sjogren's Syndrome
Sjögren syndrome is an autoimmune disease, responsible for xerostomia and xerophthalmia. Other organs and tissues can be affected: the skin, vaginal and nasal mucous membranes.
- Trial name
- TOG_SJOGREN (NCT04909112)
- Testing
- Evaluation of olfactory function, Evaluation of taste function, Evaluation of (intra-nasal and oral) trigeminal functions
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Pulpitis, Pulp Disease, Dental
Bioactive Materials in Pulp Therapy of Primary Teeth
The purpose of this study is to compare the clinical and radiographic success of a new injectable, fast setting bioceramic root repair material (BC RRM) putty with mineral trioxide aggregate (MTA) in pulpotomy procedures of…
- Trial name
- NCT04795830
- Testing
- Bioceramic root repair material as pulp dressing in pulpotomy in primary molars, Mineral Trioxide Aggregate as pulp dressing in primary molars (MTA)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Gingival Recession, Generalized, Graft Reaction
The Healing of Soft Tissue Augmentation by Acellular Dermal Matrix and Autogenous Subepithelial Connective Tissue Graft
The study team proposes to prospectively compare the healing outcomes of autogenous soft tissue connective tissue graft (CTG) and Acellular dermis matrix (ADM) in a split-mouth design study for patients requiring modification of…
- Trial name
- NCT03954028
- Testing
- Gingival Punch Biopsy after healing of Gingival Soft Tissue Augmentation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Malaria
Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant Women
This is a clinical trial being done to find better ways to reduce malaria in the community. Malaria is caused by a parasite that is spread by mosquitoes.
- Trial name
- NCT07358767
- Testing
- Artemether-lumefantrine (AL)
- Where
- Ghana
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- Noguchi Memorial Institute for Medical Research
Temporomandibular Disorder
Botulinumtoxin A as a Treatment for Myalgia and Myofacial Pain in Patient With Temporomandibulardisorders
Both patients and remitters ask for treatment with Botulinumtoxin A (BTX) with the hope that it will be an effective aid for pain, but little is known regarding if the effect is dose dependent.
- Trial name
- NCT06941636
- Testing
- 5U/0,1 ml Botulinum toxin A, 10U/0,1 ml Botulinum toxin A
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Region Stockholm
Acute Bacterial Infections, Acute Viral Infections
300 Antibody Diagnostic Test Kit
For the development of a Point of Care IVD test kit for acute phase disease detection against a variety of bacterial and viral infections.
- Trial name
- Antibody 300 (NCT01646411)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Plasma Source
Peri-implantitis
Effect of Metallic Particles on the Progression of Peri-Implantitis
This observational cross-sectional study aims to investigate the presence and characteristics of metallic micro- and nanoparticles in peri-implant tissues and their potential association with peri-implantitis progression, the…
- Trial name
- NCT07792499
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Malocclusion, Angle Class II, Division 1
Clinical Evaluation of Bio-creative Therapy for En Masse Retraction of the Maxillary Anterior Teeth
The purpose of this study is to compare the effectiveness and efficiency of labial versus lingual biocreative therapy in achieving en masse retraction of the maxillary anterior teeth in subjects with class II malocclusion…
- Trial name
- NCT03239275
- Testing
- Biocreative therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Nasopharyngeal Carcinoma, Head and Neck Cancer
The Association of hsCRP and Radiotherapy-Induced Toxicity in Patients With Nasopharyngeal Carcinoma
The primary purpose of this study is to explore the association of high sensitivity C-reactive protein (hsCRP) and radiotherapy(RT)-induced toxicity in patients with nasopharyngeal carcinoma.
- Conditions
- Nasopharyngeal Carcinoma, Head and Neck Cancer, Toxicity Due to Radiotherapy
- Trial name
- NCT04303975
- Testing
- clinical measurements
- Volunteers
- 300 people
- Sponsor
- Jiarong Chen, MD
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