Clinical trials: Stomatognathic Diseases
Oral Cancer
Validation of Salivary Proteomic Biomarkers for Early Detection of Oral Cancer in Egyptian Population
The present investigation was conducted on 100 individuals allocated into four groups; 25 healthy controls, 25 patients having OPMDs with dysplasia; 25 patients having OPMDs without dysplasia, and 25 oral cancer patients.
- Trial name
- NCT06471270
- Testing
- histologic evaluation, biochemical analysis, clinical examination
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Dental Caries
Comparing Two Brands of Silver Diamine Fluoride for Stopping Cavities in Children
this study aims to evaluate two different materials used to stop dental caries in children. both materials are available at the market. both materials leave black stain after application.
- Trial name
- SDF (NCT07708883)
- Testing
- SDF, ToothMate®, Egypt, SDF, Advantage Arrest USA
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- National Research Centre, Egypt
Caries Class II, Caries,Dental
Clinical Performance of Advanced Self- Adhesivee Resin Composite Hybrid Restorations.
Clinical performance according to modified USPHS criteria of advanced self-Adhesive resin composite hybrid restorations is evaluated for 1 year versus conventional resin composite restorations in posterior teeth.
- Trial name
- NCT04790383
- Testing
- Advanced Self-Adhesive resin composite hybrid restorations (Surefil one (Dentsply Sirona))., Conventional resin composite restoration. (Sphere Tec, (Dentsply Sirona
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Rawda Hesham Abd ElAziz
Bone Loss, Alveolar
Outcomes of Ridge Splitting Versus Sausage Technique
The current study aims to increase the width of the alveolar bone in defective mandibular ridge with simultaneous implant placement and enhance the implant stability
- Trial name
- NCT07664605
- Testing
- Ridge split
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
White Spot Lesion
Fluoride Controlled-release System for Initial Lesions of Caries
OBJECTIVE: To evaluate in vivo the efficacy of fluoride-containing dentifrice incorporated in a controlled-release system (F-CSL, patent pending) in the remineralization of white spot lesions of caries in caries-active…
- Trial name
- NCT05139966
- Testing
- Mouthwash Product
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Photochemotherapy Reaction, Dental Pulp Necrosis
Antimicrobial Photodynamic Therapy Associated With the Conventional Endodontic Treatment: A Clinical and Microbiological Study
Microorganisms play a critical role in the etiology and pathogenesis of apical periodontitis. Enterococcus faecalis and Candida sp. are frequently associated with persistent infections.
- Conditions
- Photochemotherapy Reaction, Dental Pulp Necrosis, Polymerase Chain Reaction, Infection
- Trial name
- NCT03212729
- Testing
- ANTIMICROBIAL PHOTODYNAMIC THERAPY, Conventional endodontic treatment
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Intubation Complication, Hoarseness
Thermosoftening of Double-lumen Tube for Airway Exchanger Catheter
The purpose of this study is to investigate the effect of double-lumen tube thermal-softening before intubation on the success rate of tube exchange by airway exchange catheter.
- Conditions
- Intubation Complication, Hoarseness, Sore Throat
- Trial name
- NCT03846713
- Testing
- non-thermosoftening, thermosoftening
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Seoul National University Hospital
Head and Neck Neoplasms, Laryngeal Neoplasms
Cetuximab Plus Radiotherapy Versus Cisplatin Plus Radiotherapy in Locally Advanced Head and Neck Cancer
BACKGROUND: Concomitant radiotherapy and cisplatin (CDDP) based chemotherapy is the standard treatment for LA-NHSCC. This combined modality treatment is linked with considerable acute local and systemic toxicity.EGFR is…
- Conditions
- Head and Neck Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Pharyngeal Neoplasms
- Trial name
- CTXMAB+RT (NCT01216020)
- Testing
- cetuximab, cisplatin (associated to radiotherapy)
- Where
- 7 sites in Italy
- Volunteers
- 70 people
- Sponsor
- Azienda USL 4 Prato
Nasopharyngeal Carcinoma (NPC)
RAIRI Model-Guided Adjuvant Therapy in Nasopharyngeal Carcinoma
This study aims to evaluate a personalized approach for treating patients with locoregionally advanced nasopharyngeal carcinoma (NPC).
- Trial name
- RAIRI-NPC (NCT07590024)
- Testing
- PD-1 inhibitor, Capecitabine
- Where
- China
- Volunteers
- 651 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Oral Neoplasm
Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment
The purpose of this observational study is to evaluate the utility of the S100A7 immunohistochemistry signature-based assessment - STRATICYTE - in determining the risk of progression to cancer of clinically suspicious oral…
- Trial name
- NCT04622462
- Testing
- Standard of Care Histopathology, STRATICYTE Assessment
- Where
- 3 sites in Canada
- Volunteers
- 500 people
- Sponsor
- Proteocyte Diagnostics Inc.
Gingival Recession, Periodontal Attachment Loss
Flap Thickness Upon Root Coverage With the Use of Acellular Dermal Matrix
OrACell has been tested as a barrier in bone regenerative procedures showing promising results in new bone formation after socket preservation, but no data is available on root coverage procedures.
- Conditions
- Gingival Recession, Periodontal Attachment Loss, Periodontal Diseases, Soft Tissue Injuries
- Trial name
- NCT04802473
- Testing
- Mucogingival surgery
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Placebo and Post-bleaching Sensitivity
Purpose: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT03065673
- Testing
- Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flavia Pardo Salata Nahsan
Periodontitis, Inflammation
Calcium-vitamin D & Periodontal Therapy for Improving Metabolic and Inflammatory Profile Among Pregnant Women
The improvement of maternal and child health remains a key issue in global health. Production and improved accessibility of healthy and nutrient-rich milk-based products could potentially tackle health and nutrition inequalities…
- Trial name
- IMPROVE (NCT03148483)
- Testing
- Early PT, Delayed PT, Fortified Milk
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Abnormalities, Radiation-Induced
Evaluation of the Unstimulated Whole Saliva Flow During and After Radiotherapy, With the Use HcT20
The aim of this report was to evaluate the unstimulated whole saliva flow in patients with head and neck cancers during and after the exclusive radiotherapy with an association of lauryl-diethylene-glycol-ether sodium sulfate and…
- Trial name
- EUWSFDAR (NCT00741754)
- Testing
- Mouthrinse with HcT20
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Jaw, Edentulous, Partially
Evaluation of Marginal Bone Loss and Associated Factors Around Ziacom Dental Implants With Different Prosthetic Connection
Dental implants may suffer from bone loss around them, particularly at the upper portion where the prosthesis starts. The connection between both parts of the tooth restoration is key for avoiding micromovement during chewing…
- Trial name
- NCT05859113
- Testing
- Ziacom Galaxy dental implant with internal connical prosthetic connection, Ziacom Zinic dental implant with internal hexagonal prosthetic connection
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Gingival Recession
Treatment of Single Maxillary Gingival Recession With Loss of Inter-dental Attachment. A Randomized Controlled Clinical Trial
Background: The aim of this randomized clinical trial (RCT) was to evaluate the adjunctive benefit of Connective Tissue Graft (CTG) to Coronally Advanced Flap (CAF) for the treatment of gingival recession associated with…
- Trial name
- NCT05460182
- Testing
- CAF+CTG, CAF
- Where
- Italy
- Volunteers
- 29 people
- Sponsor
- University of Florence
Mucositis, Multiple Myeloma
Comparative Trial of Cryotherapy Versus Caphosol Versus Saline Solution Mouth Washes for the Prevention of Oral Mucositis in Patients With Multiple Myeloma Undergoing Hematopoietic Stem Cell Transplantation
Chemotherapy-induced oral mucositis is the inflammation of the oral mucous membranes, which are tissues that line the mouth. Oral mucositis is caused when chemotherapy attacks and kills the rapidly-dividing cells in the oral…
- Trial name
- NCT01066624
- Testing
- 0.9% Sodium Chloride irrigation solution, Cryotherapy (ice chips), Calcium phosphate (Caphosol) Ca2+/PO43- mouth rinse
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Sensitivity, Tooth
The Association of CPP-ACPF Associated With LASER in the Treatment of Tooth Sensitivity After at Home Bleaching
Tooth whitening is a procedure that has been increasingly requested by patients around the world, whether at home or in office bleaching. Tooth sensitivity is the main side effect of bleaching.
- Trial name
- NCT05298059
- Testing
- Laser of low frequncy, CPP-ACPF
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Mandibular Reconstruction, Dental Implant
Simultaneous Dental Implant in Free Vascularized Bone Flaps for Jaw Reconstruction
After jaw resection, free vascularized bone flaps are frequently used for repairing maxillofacial defects. Simultaneous dental implantation is more preferable to secondary implantation as it saves the patients from going through…
- Conditions
- Mandibular Reconstruction, Dental Implant, Free Tissue Flaps, Jaw Neoplasms
- Trial name
- NCT05405179
- Testing
- Simultaneous dental implantation
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- The University of Hong Kong
Malignant Lymphoma of Lymph Nodes of Inguinal Region, Malignant Lymphoma of Lymph Nodes of Axillary
Optical Detection of Peripheral Nerve Bundles During Surgery
Investigation of application possibilities of optical spectroscopy within the field of surgical resection procedures to spare nerve tissue.
- Conditions
- Malignant Lymphoma of Lymph Nodes of Inguinal Region, Malignant Lymphoma of Lymph Nodes of Axillary, Malignant Lymphoma of Lymph Nodes of the Cervix, Carcinoma of Parotid Gland
- Trial name
- NerveSpect (NCT01731379)
- Testing
- Surgical resection
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- Philips Healthcare
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.