Clinical trials: Stomatognathic Diseases
Pulp Necrosis, Regeneration
Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots
This multi-center exploratory clinical trial is a randomized trial designed to test whether a regenerative endodontic procedure using tissue engineering principles (REGENDO), or a revascularization (REVASC) endodontic procedure…
- Trial name
- NCT01976065
- Testing
- Triple Antibiotic Paste, Standard Treatment
- Where
- 4 sites in United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Kenneth Hargreaves
Lymphoma, Non-Hodgkin's, Adult, Lymphoma, Hodgkin's, Adult
Safety, Tolerability, PK/PD of FE 203799 in Adults With Lymphomas
RATIONALE: The integrity of the intestinal mucosa is a key factor for the preservation of a normal gut function. Damage of the epithelium (i.e.
- Trial name
- NCT03417765
- Testing
- FE 203799
- Sponsor
- GlyPharma Therapeutics
Periodontitis, Chronic, Chewing Problem
Assessment of Masticatory Performance in Periodontitis
The loss of periodontal attachment contributes to reduced masticatory performance and has a negative impact on general health.This clinical trial aims to assess the status of masticatory performance among patients with stage I…
- Conditions
- Periodontitis, Chronic, Chewing Problem, Inflammation
- Trial name
- NCT06426069
- Testing
- Masticatory efficiency assessment
- Where
- India
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Gingival Recession
Comparison of Root Coverage Outcomes by NORD Flap Versus Subepithelial Connective Tissue Graft in RT1 Gingival Recession
Management of GR in the initial stages (when there is no inter proximal attachment and bone loss involved) has better clinical outcomes and reduces the chances of further progression of recession.
- Trial name
- Recession type (NCT05844254)
- Testing
- novel overlapping rotated double (NORD) flap
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tumor
Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors
This is a study to assess the combination of PXD101 and 5-Fluorouracil (5-FU)in patients with advanced solid tumors. The primary goal of the study is to understand the safety, anti-tumor activity, and how the study drug behaves…
- Trial name
- NCT00413322
- Testing
- belinostat, 5-Fluorouracil (5-FU)
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- Valerio Therapeutics
Pemphigus, Bullous Pemphigoid
Human Leukocyte Antigen Class II (DRB1 and DQB1) Alleles and Haplotypes Frequencies in Patients With Pemphigus Vulgaris Among the Russian Population
Pemphigus is a rare autoimmune life-threatening blistering condition affecting skin and mucous membranes. Pemphigus belongs to a family of polygenic disorders.
- Conditions
- Pemphigus, Bullous Pemphigoid, Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
- Trial name
- NCT05284929
- Testing
- A single blood sample for HLA typing
- Where
- Russia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sechenov University
Dental Caries
A Clinical Study to Assess an Experimental Dentifrice in an Experimental Model of Early Stage Caries
The aim of this study is to evaluate the relative efficacy of an experimental dentifrice containing 1150 parts per million (ppm) fluoride (as sodium fluoride [NaF]) to remineralize early stage caries type lesions in an in situ…
- Trial name
- NCT06949072
- Testing
- Test Dentifrice, Reference Dentifrice, Negative Control Dentifrice
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- HALEON
Trigeminal Neuralgia, Headache Disorders
Trigeminal Ganglion RFT vs Maxillary/Mandibular PRF in the Treatment of Trigeminal Neuralgia
Trigeminal ganglion (TG) radiofrequency thermocoagulation (RFT) and ultrasound (US)-guided maxillary or mandibular (max/mand) pulsed radiofrequency (PRF) are two interventional procedures for the treatment of trigeminal neuralgia…
- Trial name
- NCT06366139
- Testing
- Radiofrequency thermocoagulation of the trigeminal ganglion, Maxillary/Mandibular nerve pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Diskapi Teaching and Research Hospital
Facial Asymmetry
Asymmetry Index From Photogrammetric Analysis
We propose a transversal observational study, to be performed on three-dimensional images acquired through photogrammetry of patients who will undergo orthodontic treatments.
- Trial name
- NCT07807657
- Testing
- stereophotogrammetry
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dental Caries
Comparison of Clinical and Radiographic Outcomes of SMART Technique vs ART in Primary Molars
This study conducted on thirty children aged 3-6 years old of both genders, have bilateral carious lower first primary molars. Pre-operative periapical x- ray were taken for both sides.
- Trial name
- NCT05438381
- Testing
- Atraumatic Restorative Technique (ART), SMART Technique
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Adenoid Hypertrophy, Masseter Muscle
Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study
The goal of this observational study is to evaluate the effect of adenoid hypertrophy on the masseter muscle in children aged 3 to 8 years.
- Conditions
- Adenoid Hypertrophy, Masseter Muscle, Malocclusion
- Trial name
- NCT07094581
- Testing
- USG
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Melis AKYILDIZ
Temporomandibular Joint Dysfunction, TMD
Effects of Core Strengthening Exercises for Treating TMD
Temporomandibular disorders (TMD) are commonly managed with non-invasive interventions such as manual therapy, therapeutic exercise, relaxation techniques, and patient education.
- Conditions
- Temporomandibular Joint Dysfunction, TMD, TMJ Internal Derangement, Myofascial Pain
- Trial name
- NCT07226505
- Testing
- Experimental: Group 1: Core Strengthening, Group 2: Standard TMD PT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Loyola University
Peri-Implantitis
Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis
Decontamination procedure is a challenging factor that affects the success of surgical regenerative therapy (SRT) of peri-implantitis.
- Trial name
- NCT03018795
- Testing
- Decontamination of implant surfaces
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Gazi University
Autism Spectrum Disorder, Autism
Oral Health Care in Autism Spectrum Disorder
Persons with autism spectrum disorder (ASD) are characterized by impairments in social interactions, speech and communication, restricted patterns of behaviour, and unusual sensory sensitivities.
- Trial name
- CREASED (NCT03830541)
- Testing
- Oral care delivery analysis in participants with ASD
- Volunteers
- 52 people
- Sponsor
- University of Novi Sad
Pain, Postoperative, Tooth Diseases
Efficacy and Safety of Ibuprofen and Caffeine in Dental Pain
The primary objective of this study is to compare the efficacy of a combination product containing ibuprofen 400 mg and caffeine 100 mg versus either ingredient alone as well as placebo for the treatment of post-surgical dental…
- Trial name
- NCT01929031
- Testing
- ibuprofen + caffeine, ibuprofen, caffeine
- Where
- United States
- Volunteers
- 562 people
- Sponsor
- Boehringer Ingelheim
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Partial Edentulism, Tooth Disease
Assessment of the Effect of a Novel Surface Roughness Treatment on Dental Implants on Integration Success
A study where dental implants with different roughened surfaces will be evaluated for the ability to resist countertorque forces.
- Trial name
- Luna (NCT01529801)
- Testing
- Osseotite Certain Tapered Group A, Osseotite Certain Tapered Group B, Osseotite Certain Tapered Group C
- Where
- Chile
- Volunteers
- 80 people
- Sponsor
- ZimVie
Sjogren's Syndrome
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease
Background: Sjogren disease is an autoimmune disease - that is, a disease that causes the body's immune system to attack its own organs and tissues. Sjogren disease can affect the kidneys, lungs, or other organs.
- Trial name
- NCT07281456
- Testing
- Tofacitinib
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Dental Caries, Dental Cavities
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
The purpose of this clinical trial is to evaluate and compare the outcomes of selective carious tissue removal versus stepwise carious tissue removal in young permanent teeth with deep carious lesions.
- Trial name
- SELECT (NCT06944028)
- Testing
- Selective excavation, Stepwise excavation
- Where
- Sweden
- Volunteers
- 666 people
- Sponsor
- Karolinska Institutet
Edentulous Jaw, Periodontitis
Effect of Implant Treatment and/or Dietary Advice on the Nutrition of Edentulous Ageing Subjects
Loss of masticatory function consequent to tooth loss is associated with changes in food choices and insufficient nutrition intake.
- Trial name
- NCT05334407
- Testing
- Implant-supported full-arch fixed dental prostheses（dental intervention,DE）, Dietary intervention tailored to the dental status (dietary intervention, DI), Delayed implant-supported full-arch fixed dental prostheses（dental intervention,DE）
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
The first 5,000 results can be paged through. Add a filter or change the sort order to reach the rest.