Clinical trials: Stomatognathic Diseases
Aphthous Stomatitis
Prevention of Recurrent Aphthous Stomatitis Using Vitamins
The purpose of this research study is to find out if taking a multivitamin daily can affect the number of canker sores that people get and how long they last.
- Trial name
- NCT00527306
- Testing
- multivitamin
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- UConn Health
Gingival Recession
Use of Platelet Rich Fibrin in Addition to CAF and SCTG for Treatment of Gingival Recession
This research will be conducted in an attempt to achieve complete root coverage with physiologic probing depth and a harmonious view with the adjacent tissues using Platelet rich fibrin in conjunction with Coronally advanced flap…
- Trial name
- NCT03199118
- Testing
- CAF +SCTG, platelet rich fibrin
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Recurrent Aphthous Stomatitis, Oral Ulcers
Efficacy of 5% Chitosan Nanoparticle Paste in the Treatment of Recurrent Aphthous Stomatitis
The purpose of this study is to evaluate the therapeutic clinical efficacy of a synthesized 5 wt.% chitosan nanoparticle paste compared to a standard topical corticosteroid (triamcinolone acetonide 0.1% oral paste) in patients…
- Trial name
- NCT07702474
- Testing
- Triamcinolone Acetonide 0.1% Oral Paste, 5 wt.% Chitosan Nanoparticle Paste
- Volunteers
- 30 people
- Sponsor
- Kerman University of Medical Sciences
Dental Anxiety, Dental Fear
Dental Anxiety in Children Attending Emergency Versus Routine Dental Care
The goal of this observational study is to learn whether children who come to a pediatric dental emergency clinic have higher dental anxiety than children who come for routine dental care.
- Trial name
- NCT07882914
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Marmara University
Peri-Implantitis
Non-invasive Solution for Periodontal and Peri-implant Diseases (INPERIO)
DESCRIPTION: The Investigational Product "A-Ce toughened TZP nanocomposite implant" is a Medical Device (MD) intended for the dental rehabilitation of edentulous sites with fixed prosthesis.
- Trial name
- INPERIO (NCT03977714)
- Testing
- Zirconia implants with G3-coated abutments (test implants and abutments), Zirconia implants with control abutments (test implants, negative control abutments), Titanium implants with G3-coated abutments (control implants, test abutments)
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Nanoker Research S.L.
Rheumatoid Arthritis, Lupus Erythematosus, Systemic
Lessening the Impact of Fatigue in Inflammatory Rheumatic Diseases
Fatigue is common and disabling for most patients with inflammatory rheumatic disease. Therapies designed to improve physical activity and 'talking' treatments, which positively help patients change the way they think and behave…
- Conditions
- Rheumatoid Arthritis, Lupus Erythematosus, Systemic, Axial Spondyloarthritis, Psoriatic Arthritis
- Trial name
- LIFT (NCT03248518)
- Testing
- Usual Care, Cognitive behavioural approach, Personalised Exercise Programme
- Where
- 6 sites in United Kingdom
- Volunteers
- 368 people
- Sponsor
- University of Aberdeen
Pharyngitis
Best Assessment of Sore Throat and Antibiotic Prescribing
This project aims to investigate if an organisational change of patient flow away from medical practitioners can reduce unnecessary antibiotic prescribing in patients attending with a sore throat as the main complaint.
- Trial name
- BASTA (NCT06114706)
- Testing
- Physicians assess patients, Nurses assess patients, Pharmacists assess patients
- Where
- 4 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Vastra Gotaland Region
Gingival Recession, Localized
Comparing Two Different Tunneling Technique for Gingival Recession Treatment Using Two Different Matertial
The goal of this clinical trial is to compare two different tunneling surgical technique in treatment of gingival recession using two different materials.
- Trial name
- NCT06065774
- Testing
- The Laterally Closed Tunnel Technique with SCTG, The Laterally Closed Tunnel Technique with collagen matrix mucograft, Modified Coronally Advanced Tunnel Technique with SCTG.
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Gingival Recession, Gingival Recession, Localized
The Effect of Using Injectable Platelet-rich Fibrin on Root Surface Closure in Patients with Gingival Recession.
Gingival recession is the term used to describe the apical positioning of the marginal gingiva from the enamel-cementum junction.
- Trial name
- NCT05591326
- Testing
- i-PRF application procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Berceste Guler
Dentin Sensitivity
Effectiveness of Two Water-Based Potassium Oxalate Desensitizers on Dental Hypersensitivity
This study will compare the safety and effectiveness of two water-based potassium oxalate desensitizers on existing dentinal hypersensitivity.
- Trial name
- NCT02152826
- Testing
- Potassium oxalate
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Acute Pharyngitis
Yanlishuang Buccal Dropping Pills for Acute Pharyngitis
Acute pharyngitis commonly causes sore throat and pain on swallowing. This multicenter trial will compare Yanlishuang Buccal Dropping Pills with a matching placebo in 400 adults aged 18 to 65 years whose acute pharyngitis began…
- Trial name
- YLS-AP-RCT (NCT07761013)
- Testing
- Yanlishuang Buccal Dropping Pills
- Where
- 10 sites in China
- Volunteers
- 400 people
- Sponsor
- Beijing University of Chinese Medicine
Temporomandibular Joint Disorders
Therapeutic Response of Ultrasound and Muscular Stretching in Temporomandibular Disorder Patients
The combination of ultrasound and muscular stretching may have positive effects on pain relief and on the balance of the masticatory muscles activity.
- Trial name
- NCT02139735
- Testing
- Ultrasound, Ultrasound associated with stretching
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Universidade Federal de Santa Maria
Nasopharyngeal Carcinoma
TPC vs PF as Induction Chemotherapy Combined With CCRT for Stage IVa-b Nasopharyngeal Carcinoma
The purpose of this study is to compare the survival and toxicity of TPC (TAXOL, DDP AND CAPECITABINE ) VS PF (cisplatin and 5-Fluorouracil) as induction chemotherapy combined with concurrent chemoradiotherapy (CCRT) for stage…
- Trial name
- NCT02940925
- Testing
- Drug: Taxol,cisplatin and capecitabine, Drug: Cisplatin and 5-Fluorouracil
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Sun Yat-sen University
Head and Neck Cancer
Everolimus and Docetaxel in Treating Patients With Recurrent, Locally Advanced, or Metastatic Head and Neck Cancer
RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.
- Trial name
- DORA (NCT01313390)
- Testing
- docetaxel, everolimus, laboratory biomarker analysis
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- University College, London
Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer
Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer
This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy.
- Conditions
- Radiation-Induced Oral Mucositis, Head &Amp; Neck Cancer, Head &Amp; Neck Squamous Cell Carcinoma
- Trial name
- RICE-MUC (NCT07242859)
- Testing
- rice bran
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Christina Milad Lobos
Chronic Periodontitis
Evaluation of Local Delivery of Aloe Vera Gel as an Adjunct to Non-surgical Treatment in Patients With Chronic Periodontitis
Aim of the current study was to evaluate the effect of Aloe vera gel as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis.
- Trial name
- NCT04615585
- Testing
- Aloe vera after SRP, Scaling and root planing (SRP)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Nourhan M.Aly
Experimental, Dementia
Salivary Gland Massage and Olfactory Stimulation for Relieving Feeding Difficulty and Triggering Oral Intake Among People With Dementia
Feeding difficulties are a common issue among individuals with dementia during moderate to advanced stages, particularly those in long-term care (LTC) facilities.
- Conditions
- Experimental, Dementia, RCT, Dry Mouth
- Trial name
- NCT07678515
- Testing
- SMART program (Salivary gland massage combined with aromatherapy
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Cheng Kung University
Cleft Lip and Cleft Palate, Cleft Lip Bilateral
Improving the Outcomes of Nasoalveolar Molding in Complete Bilateral Cleft Lip and Palate Neonates Using a Modification in the Design of the Conventional Molding Appliance.
The goal of this clinical trial was to improve the outcome of using the nasoalveoalr molding appliances in patients with complete bilateral cleft lip and palate.
- Conditions
- Cleft Lip and Cleft Palate, Cleft Lip Bilateral, Complete Bilateral Cleft Lip and Palate
- Trial name
- NCT07814625
- Testing
- vomer molding appliance, conventional molding appliance
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
TMJ Disorder
Effect of Order and Conjugation of Different Photobiomodulation Therapies and Anterior Repositioning Appliance in Management of TMD Cases
This study aimed to evaluate the effect of using Low level laser therapy / Infrared led therapy with anterior repositioning appliance in anterior dislocation patients with reduction (ADDwR) concerning: 1.
- Trial name
- NCT06103110
- Testing
- Photobiomodulation
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Demineralization, Tooth, White Spot Lesion of Tooth
Preventive Effects of Silver Diamine Fluoride on Early Enamel Caries
Fixed orthodontic patients are at risk of developing dental caries. Topical application of fluoride varnish (FV) around the orthodontic brackets and using fluoridated mouth rinses have been suggested to prevent the formation of…
- Conditions
- Demineralization, Tooth, White Spot Lesion of Tooth, Fixed Appliances, Early Caries Lesions
- Trial name
- NCT06797882
- Testing
- Silver diamine fluoride- potassium iodide, Fluoride varnish, 0.9 % saline
- Where
- Malaysia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
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