Clinical trials: Stomatognathic System
Dentin Sensitivity, Hypersensitivity
A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH
Dentin hypersensitivity (DH) is defined as sharp pain of a shorter duration arise from exposed dentin in response to several chemicals and thermal or tactile stimuli that cannot be ascribed to other dental defects".
- Conditions
- Dentin Sensitivity, Hypersensitivity, Cervical Lesion
- Trial name
- NCT06463938
- Testing
- Active comparator, Experimental group, Combination of laser and paste
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Malocclusion, Maxillofacial Injuries
A Cohort Prospective Study of Predictors Influencing the Quality of Visualization of the Operating Field During Orthognathic Surgery
It is very important to decrease the bleeding during bimaxillary osteotomy in order to increase the visibility of the surgical site.
- Conditions
- Malocclusion, Maxillofacial Injuries, Orthodontics, Hemorrhage
- Trial name
- NCT05814991
- Testing
- Nitroglycerin solution, monitoring of cerebral oxygen saturation
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Sjogren Disease
A Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren's
This is a phase 2 study to evaluate the effects of sibeprenlimab 400 mg administered subcutaneously (SC) every 4 (Q4) weeks as an add-on to background treatment in participants with Sjögren's disease.
- Trial name
- EnVISage (NCT06928142)
- Testing
- Sibeprenlimab
- Where
- 64 sites in United States, Argentina and 6 more
- Volunteers
- 83 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Oral Lichen Planus, Thyroid Disease
Association Between Oral Lichen Planus and Thyroid Disease
The goal of this observational study is to determine the prevalence of thyroid disease in adults with oral lichen planus (OLP) treated at the Dental Hospital of the University of Barcelona (HOUB), and to evaluate the association…
- Trial name
- NCT06550154
- Testing
- Data collection
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Parkinson Disease
STN-DBS and the Risk of Sialorrhea
OBJECTIVE: The aims of this study were to assess the incidence rate and risk factors for sialorrhea in the long-term follow-up in a cohort of 170 patients with advanced Parkinson's disease [84 with deep brain stimulation (DBS)…
- Trial name
- NCT06090929
- Testing
- STN-DBS
- Where
- China
- Volunteers
- 234 people
- Sponsor
- Qilu Hospital of Shandong University
Sjögren Syndrome, Pulmonary Hypertension
Early Detection of Pulmonary- and Pulmonary Vascular Disease in Sjögren Syndrome
According to the literature available pulmonary hypertension is present in 12 to 23% of patients suffering from Sjögren Syndrome. However epidemiological data are based on non-invasive measurements using echocardiography.
- Trial name
- NCT02752269
- Where
- Austria
- Volunteers
- 86 people
- Sponsor
- Medical University of Graz
Chronic Periodontitis, Type 2 Diabetes Mellitus
Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal Therapy
1. Are adipokines involved in pathogenesis of periodontal disease in diabetic patients? 2. Does their level change after periodontal therapy?
- Trial name
- NCT02174146
- Testing
- non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sleep Apnea, Obstructive, Tonsillitis
Laryngeal Mask Airway in Pediatric Adenotonsillectomy
The study will compare how often the tubing kinks when a LMA (laryngeal mask airway) with modified retractor is used compared to use of an endotracheal tube (ETT) and non modified retractor is used.
- Trial name
- LMA (NCT01695980)
- Testing
- ETT with non modified retractor, LMA with modified retractor
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Eastern Virginia Medical School
Temporomandibular Joint Dysfunction Syndrome
Physiotherapy and Deontology in the Temporomandibular Joint Dysfunction in Patients With Fibromyalgia Syndrome.
The purpose of this study is to determine whether kinesitherapy techniques and a myofascial therapy protocol are effective in the treatment of temporomandibular joint dysfunction in patients with fibromyalgia syndrome.
- Trial name
- NCT01800279
- Testing
- Physiotherapy Protocol, Deontology Therapy
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universidad de Almeria
Swallowing Disorder, Oropharyngeal Dysphagia
Effectiveness of an Optimal-Massive Intervention in Older Patients With Dysphagia
The aim of this study is to evaluate the efficacy of an optimal-massive intervention (OMI) based on increasing shear viscosity of fluids, nutritional support with oral nutritional supplements (ONS) and triple adaptation of food…
- Conditions
- Swallowing Disorder, Oropharyngeal Dysphagia, Respiratory Infection, Malnutrition
- Trial name
- OMI (NCT04581486)
- Testing
- Optimal-Massive Intervention, Control (standard clinical practice)
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Hospital de Mataró
Dental Caries
Safety and Performance Evaluation of the Calcivis System
This is a prospective, multi-centre clinical study to evaluate the safety and performance of the Calcivis Caries Activity Imaging System.
- Trial name
- NCT02780856
- Testing
- Imaging with the Calcivis System
- Where
- 4 sites in United Kingdom
- Volunteers
- 110 people
- Sponsor
- Calcivis Ltd
Mucositis (MeSH Unique ID: D052016), Stomatitis (MeSH Unique ID: D013280)
OZOCLO_MUCOSITIS: a New Protocol for Prevention of Oral Mucositis
Oral mucositis (OM) is a significant side effect of cytotoxic anti-cancer chemotherapy and HN radiotherapy. CT-associated OM (CT-OM). It is the ulcerative phase that is most painful and associated with poor health outcomes.
- Trial name
- OZOCLO_MUCOS (NCT05211622)
- Testing
- 1. alpha acid lipoic - tables, 2. ozonated oil - mouthwash, 3. chlorhexidine 0,2% - mouthwash
- Volunteers
- 80 people
- Sponsor
- University of Palermo
Sleep Apnea, Sleep Apnea, Obstructive
Effect Of Sleep Apnea Treatment On Temporo-Mandibular Disorders
Aims of this research are to detect if an improvement in sleep pattern in patients suffering from obstructive sleep apnea (OSA), produces a reduction in pain and dysfunction in the orofacial area by examining variation in…
- Conditions
- Sleep Apnea, Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Pain
- Trial name
- NCT04948541
- Testing
- osa treatment, no treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Anna Alessandri Bonetti
Bell Palsy
Ultrasound-guided Combined Perineural and Intramuscular Dextrose Injection for Management of Refractory Bell's Palsy
Bell's palsy (BP) is characterized by idiopathic acute weakness of the facial muscles associated with compression of the facial nerve.
- Trial name
- NCT07728331
- Testing
- Ultrasound-guided combined perineural and intramuscular dextrose injection.
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Al-Azhar University
Diabetes Mellitus., Chronic Periodontitis
Periodontal Treatment in Non-controlled Type 2 Diabetes Mellitus Patients. Clinical Trial
Periodontitis is an infectious disease that destroys the tooth supporting tissues and triggers a local and systemic immune response.
- Trial name
- FONIS12I2106 (NCT01904422)
- Testing
- conventional periodontal treatment
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Universidad de los Andes, Chile
Mucositis Oral
Effect of Probiotic Use Bifidobacterium Animalis Subsp. Lactis in Peri-implant Mucositis
Peri-implant disease is an inflammatory process of bacterial etiology that can affect the tissues around the implants and can be classified as peri-implant mucositis or peri-implantitis.
- Trial name
- Mucosite prob (NCT04187222)
- Testing
- Mechanical debridements, Bifidobacterium animalis subsp. lactis
- Where
- Brazil
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Facial Paralysis, Bell Palsy
Artificial Eye Blinking Stimulation Following Paralysis of the Facial Nerve
Artificial eye blinking stimulation following damage to the facial nerve. Group 1 - Patients with a persistent unilateral facial paralysis (palsy) that underwent an operation for facial reanimation Group 2 - Patients with…
- Trial name
- Bioniceye (NCT04153916)
- Testing
- Neurotrigger eye blinking stimulator
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Neurotrigger Ltd
Myofacial Pain Syndrome
Extracorporeal Shock-wave Therapy in Myofascial Pain Syndrome
Introduction: Myofascial pain syndrome (MPS) is a syndrome characterized by painful trigger points on palpation located at certain points of common muscles of the musculoskeletal system.
- Trial name
- ESWT (NCT06987721)
- Testing
- Modus ESWT-Focused, Modus ESWT-Radial
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Ankara City Hospital Bilkent
Sjogren's Syndrome, Autoimmune Diseases
Exploratory Study of the Efficacy of HuMoSCs (Human Monocyte-derived Suppressor Cells) on Glandular Involvement in Sjögren's Syndrome
Sjögren's syndrome is an autoimmune disease. Dry syndrome is a key feature of this condition, almost always leading to dryness of the mouth and eyes.
- Trial name
- Immuno-DRYve (NCT07861828)
- Testing
- Blood sample, Salivary gland biopsy
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Rheumatoid Arthritis, Spondyloarthritis
Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases
The prognosis of rheumatic diseases has improved considerably with development of therapy. However, infections are considered the most important cause of morbidity and mortality in this group of patients.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Systemic Lupus Erythematosus (SLE), Dermatomyositis (DM)
- Trial name
- NCT01151644
- Testing
- Anti-pandemic H1N1 influenza vaccine
- Where
- Brazil
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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