Clinical trials: Stomatognathic System
Cleft Lip
Alveolar Bone Grafting Outcome Between Patient With and Without Orthodontic Treatment
Alveolar bone grafting (ABG) is an essential part of the surgical management of cleft lip and palate patients. This procedure could obliterate oronasal fistula, stabilize dental arch, offer bone matrix for adjacent teeth…
- Trial name
- NCT02454998
- Testing
- orthodontic treatment
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Cleft Lip and Palate
Alt-RAMEC Expansion and Protraction by EDO in Cleft Lip and Palate Patient
Evaluate the treatment outcome of Alternate Rapid Maxillary Expansion and Constriction Alt-RAMEC protocol on patients with cleft lip and palate, using a differential opening expander and face mask which will be measured and…
- Trial name
- NCT04970095
- Testing
- Maxillary Expander with Differential Opening (EDO), Petit Face Mask
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Eczema, Allergy
Probiotics in Prevention of Allergies, Obesity and Caries
During the period of 2000-2003, 179 healthy, term infants with no previous signs of allergic disease were recruited and randomized to daily intake of cereals with or without the addition of Lactobacillus paracasei subspecies…
- Conditions
- Eczema, Allergy, Asthma, Obesity
- Trial name
- ELEFANT (NCT00894816)
- Testing
- Lactobacillus F19
- Where
- Sweden
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Umeå University
Cancer
Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Cancer
RATIONALE: Suberoylanilide hydroxamic acid may stop the growth of cancer cells by blocking the enzymes necessary for cancer cell growth.
- Trial name
- NCT00045006
- Testing
- vorinostat
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Sialorrhea, Cerebral Palsy
Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral Palsy
The purpose of this study is to evaluate the safety and efficacy of botulinum toxin-A in salivary glands as a treatment for decrease drooling in patients with cerebral palsy and evaluate the long-term effects and tolerance .
- Trial name
- NCT01489904
- Testing
- BOTULINUM NEUROTOXIN TYPE-A
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Vall d'Hebron
Behcet Disease, Cranial Nerve Disorder
Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters
The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features.
- Trial name
- NCT07135063
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Buccal Fat Pad, Cleft Palate
Evaluating Salivary α - Amylase Levels Following Trigona Sp Honey Application To Post Palatoplasty Patients: A Pilot Randomized Clinical Study
Palatoplasty is a surgical procedure performed to restore palatal continuity and improve velopharyngeal function in patients with cleft palate.
- Conditions
- Buccal Fat Pad, Cleft Palate, Honey, Salivary Alpha Amylase
- Trial name
- NCT07610993
- Testing
- Trigona sp honey with the buccal fat pad technique, framicetyn sulfate dressing with the buccal fat pad technique, Trigona sp. honey dressing without the buccal fat pad technique
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Hasanuddin University
Myocarditis, ANCA Associated Vasculitis
EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases
Inflammatory Cardiovascular Diseases and Autoimmune Rheumatic Diseases (ICARDs) encompass cardiovascular involvement in connective tissue diseases, vasculitis, and primary inflammatory cardiac processes affecting all layers of…
- Conditions
- Myocarditis, ANCA Associated Vasculitis, Pericarditis, Systemic Sclerosis
- Trial name
- EACVI-INFLAME (NCT07077304)
- Testing
- observational study
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bruxism, Sleep-Related
Interest of the BRUXENSE Occlusal Splints for Bruxism Diagnosis: a Feasibility Study
There is no accurate diagnosis method for bruxism for now. Consequences of bruxism over teeth, muscles and articulation of the jaw are important.
- Trial name
- BRUXENSE (NCT03363204)
- Testing
- BRUXENSE occlusal splint
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Hospices Civils de Lyon
Bladder Cancer, Glioma
Evaluation of the Distribution of 64Cu/68Ga Labeled CM500 in Healthy Volunteers and Patients With Cancer
The objective of this study is to assess two novel positron emission tomography (PET) radiotracers, [64Cu]CM500 and [68Ga]CM500, for Positron Emission Tomography-Magnetic Resonance Imaging (PET-MR) and Positron Emission…
- Conditions
- Bladder Cancer, Glioma, Glioblastoma (GBM), Breast Cancer
- Trial name
- NCT07781852
- Testing
- [64Cu]CM500, [68Ga]CM500, PET/MR
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lumina Pharmaceuticals Inc
Periodontitis, Diabetes
Effect of Non Surgical Treatment of Periodontitis on Diabetes Control
The aim of this study is to investigate the effects of non-surgical periodontal treatment on the metabolic control of type2 diabetes patients.
- Trial name
- PARODIA1 (NCT02745015)
- Testing
- non-surgical periodontal treatment
- Where
- Cameroon
- Volunteers
- 45 people
- Sponsor
- Yaounde Central Hospital
Radiation Indused Oral Mucositis
Comparison Between the Effect of Aloe Vera and Benzydamine Hydrochloride Mouth Gel on Prevention of Pain and Progression of Radiation-induced Oral Mucositis
Oral mucositis, a painful inflammation and ulceration of the mucous membranes in the mouth, is commonly seen in patients undergoing chemotherapy or radiation therapy.
- Trial name
- NCT06862817
- Testing
- Aloe vera gel, Benzydamine Hydrochloride 0.15% Oral gel, bioadhesive gel
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Leukemia, Lymphoma
Pharmacokinetic Study of Palifermin in Subjects Receiving Radiation Therapy and Chemotherapy Followed by Blood Stem Cell Support
Open label palifermin will be administered to subjects who are at a risk of developing mucositis after radiotherapy and chemotherapy followed by blood stem cell support.
- Conditions
- Leukemia, Lymphoma, Myeloma
- Trial name
- NCT00070616
- Testing
- Palifermin 6 x 60 μg/kg/day, Palifermin 2 x 180 μg/kg/day, radiotherapy
- Volunteers
- 25 people
- Sponsor
- Swedish Orphan Biovitrum
Non-Hodgkin Lymphoma, Hodgkin Lymphoma
Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors
The goals of this study is to determine if nelfinavir can target Epstein-Barr virus (EBV) and Kaposi sarcoma-associated herpesvirus (KSHV) in patients with certain cancers.
- Conditions
- Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Kaposi Sarcoma, Gastric Cancer
- Trial name
- NCT02080416
- Testing
- Nelfinavir
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Cairo University, Nonvital Tooth
Clinical Evaluation of Two Post Systems for Single Crown Restoration of Anterior Teeth
This randomized controlled trial evaluates two post systems used to restore endodontically treated (root canal treated) maxillary anterior teeth with 1-2 missing coronal walls.
- Trial name
- NCT07827755
- Testing
- Custom-Fit UHMWPE Fiber Post with Composite Core
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Cairo University
Bell Palsy
Do We Need to Taper Down Steroid Therapy for Bell's Palsy
Bell's palsy [BP] is defined as acute idiopathic peripheral facial palsy or paralysis. Additional symptoms frequently include pain around or behind the ear, impaired tolerance to ordinary levels of noise and disturbed sense of…
- Trial name
- NCT04406376
- Testing
- Prednisone tablet
- Where
- Israel
- Volunteers
- 124 people
- Sponsor
- Carmel Medical Center
Malocclusion
0.018 or 0.022 Bracket Slot System More Effective in Orthodontic Treatment?
The purpose of this study is to compare the 0.018-inch and 0.022-inch bracket slot systems to determine which is more effective for orthodontic treatment .
- Trial name
- 18v22 (NCT02080338)
- Testing
- Orthodontic bracket slot system
- Where
- 3 sites in United Kingdom
- Volunteers
- 187 people
- Sponsor
- David Bearn
Obstructive Sleep Apnea Syndrome, Temporomandibular Disorders
Side Effects of Mandibular Advancement Devices
Sleep-related breathing disorders (SBAS) are one of the most common causes of non-restorative sleep. Sleep therapy options include positive pressure ventilation with continuous positive airway pressure (CPAP) masks, mandibular…
- Trial name
- NCT04050514
- Testing
- H-MAD with a hinge system according to Herbst
- Where
- 9 sites in Germany
- Volunteers
- 65 people
- Sponsor
- University Medicine Greifswald
Tinnitus, Subjective, Temporomandibular Disorder
Evaluation of the Effect of Muscle Activity on Subjective Tinnitus in Temporomandibular Disorders
Treatment of Temporomandibular Joint Disorder can help reduce subjective tinnitus levels. This treatment changes the electrical activity of the patient's chewing muscles.
- Trial name
- NCT05830604
- Testing
- Occlusal Splint Treatment- Non Invasive treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kutahya Health Sciences University
Jaw, Edentulous
Comparison of Early and Late Loading in the Edentulous Upper Jaw Using Cresco Prosthetic System on Straumann Implants
Comparison of early and late loading of implants supporting full each prosthesis in upper jaw, using the Cresco prosthetic system on Straumann implants.
- Trial name
- NCT00922935
- Testing
- Cresco, Straumann components
- Where
- 2 sites in Sweden
- Volunteers
- 36 people
- Sponsor
- Institut Straumann AG
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