Clinical trials: Stomatognathic System
Metastatic Tumor, Advanced Solid Tumor
A Clinical Study of Anti-CD70 UCAR-T in Relapsed or Refractory Solid Tumors
This is a single-center, single-arm ，open-label ，dose escalation and dose extension study. In this study we plan to evaluate the safety and efficacy of CD70-targeting UCAR-T cells in the treatment of CD70-positive refractory or…
- Conditions
- Metastatic Tumor, Advanced Solid Tumor, Renal Cell Carcinoma, Ovarian Cancer
- Trial name
- NCT06383507
- Testing
- CHT101
- Volunteers
- 18 people
- Sponsor
- Zhejiang University
Trigeminal Neuralgia
Regional Anesthesia in Refractory Trigeminal Neuralgia: 21 Cases Reported to the Limoges University Hospital
Trigeminal neuralgia is defined according to the third edition of the International Classification of Headache Disorders (ICHD-3) criteria. Chronic pain can have a major impact on the quality of life.
- Trial name
- TRINEB ONE (NCT03669744)
- Testing
- telephone survey
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Limoges
Neoplasms, Arteriovenous Malformation of Central Nervous System
RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time…
- Conditions
- Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia
- Trial name
- NCT01885299
- Testing
- SRS/SBRT
- Where
- 13 sites in United States
- Volunteers
- 50,000 people
- Sponsor
- The Radiosurgery Society
Orofacial Pain, Sleep Bruxism
Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras.
- Conditions
- Orofacial Pain, Sleep Bruxism, Oral Health Related Quality of Life (OHRQoL)
- Trial name
- OSQ-MUS (NCT07714837)
- Testing
- Questionaire
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Oral Health, Parkinson Disease
Preliminary Study of the Quality of the Oral Flora in Parkinson's Patients
This is a prospective interventional clinical study whose main objective is to determine the impact of oral hygiene guidance on the oral health status of patients with Parkinson disease
- Trial name
- PARKIDENT (NCT03827551)
- Testing
- Delivery of oral hygiene advices
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Bordeaux
Periodontitis, Periodontal Disease
Investigation of the Relationship Between Periodontitis and Sleep Quality
This project aims to investigate the relationship between periodontitis and sleep quality. Its originality lies in evaluating the association between periodontal status and sleep quality together with salivary interleukin-6…
- Conditions
- Periodontitis, Periodontal Disease, Sleep Quality, Fatigue
- Trial name
- RBPSQ (NCT07421960)
- Testing
- Periodontal examinations, Collection of saliva samples, Pittsburgh Sleep Quality Index
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Pulpitis
Comparison Between Reciproc and Oneshape Systems
A randomized clinical trial to assess postoperative pain in patients with symptomatic irreversible pulpitis after using Reciproc versus One Shape rotary NiTi Systems.
- Trial name
- NCT02940782
- Testing
- Reciproc single file system, One Shape single file system, X-smart Plus, Dentsply Maillefer, Ballaigues, Switzerland
- Volunteers
- 54 people
- Sponsor
- Cairo University
Sjögren's Syndrome
Salivary Biomarkers for Sjögren's Syndrome Detection
This is a multi-center clinical study to compare the performance of a collective panel of salivary biomarkers to discriminate SS from non-SS in sicca cohorts recruited from three clinical sites with the diagnostic outcomes based…
- Trial name
- NCT01807689
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- University of California, Los Angeles
Sjogren's Syndrome
Sjogrens Syndrome Measured by Ultrasound
Ultrasound study focused on salivary gland outcomes in Sjogren's subjects
- Trial name
- NCT03411850
- Testing
- Orencia
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arthritis & Rheumatism Associates, P.C.
Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth
One Year Clinical Evaluation of Milled BioHPP Polyetheretherketone (PEEK)-Based Versus Metal Ceramic Single Crowns
Although the metal-ceramic system is still widely used to fabricate crowns and fixed partial dentures and is considered as the standard treatment in dentistry, aesthetic concerns have stimulated the development of new dental…
- Conditions
- Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth, Malformed Teeth, Malposed Teeth (Tilted, Over-erupted, Rotated, Etc.) or Spacing Between Posterior Teeth
- Trial name
- NCT03685513
- Testing
- BioHPP PEEK-based single posterior crowns, Metal ceramic single posterior crowns
- Volunteers
- 46 people
- Sponsor
- Cairo University
Cleft Lip
Silicone Gel in the Treatment of Cleft Lip Scars
Cleft lip / palate is the most common craniofacial anomaly in humans. Lip repair is one of the most important reconstructions for these patients, and is performed at around 3 months of age.
- Trial name
- NCT03314090
- Testing
- Silicone Gels
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Chang Gung Memorial Hospital
Periodontal Disease, Diabetes Mellitus, Type 2
Treating Periodontal Infection: Effects on Glycemic
The purpose of this project is to obtain important preliminary data necessary to support design of a full scale, multicenter randomized clinical trial (RCT) to evaluate the effect of treating periodontal infection on glycemic…
- Trial name
- NCT00016835
- Testing
- Subgingival scaling and metronidazole, Subgingival scaling and doxycycline
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Michigan
Measles, Mumps
Immunogenicity and Safety of Hepatitis A Vaccine Given at the Same Time of Measles, Mumps, Rubella Combined Vaccine
The present study will explore the immunogenicity of AVAXIM™ 80U-Pediatric in 12-13 months Turkish children and check if the administration of the MMR trivalent vaccine on the same day but at different site will interfere on…
- Conditions
- Measles, Mumps, Rubella, Hepatitis A
- Trial name
- NCT00313950
- Testing
- Inactivated Hep A vaccine; Attenuated Measles Mumps Rubella, Attenuated Measles Mumps Rubella; Inactivated Hep A vaccine
- Where
- Turkey (Türkiye)
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Bell's Palsy
Acupuncture With Deqi And Psychological Effects in Treatment of Bell's Palsy
The purpose of this study is to observe the influence of Deqi and neuropsychological factors on effects of acupuncture treatment for Bell's Palsy.
- Trial name
- ADAPT (NCT00685789)
- Testing
- acupuncture, deqi, acupuncture Non-manipulation
- Where
- China
- Volunteers
- 355 people
- Sponsor
- Huazhong University of Science and Technology
Periodontal Disease, Type 2 Diabetes Mellitus
Relationship of Periodontal Disease Treatment and Type 2 Diabetes Mellitus in the Gullah Population
Our overall hypothesis is that treatment of periodontal disease will produce better diabetes glycemic control (glycated hemoglobin A1c, or HbA1c) and reduced levels of the catalytically active form of matrix metalloproteinase…
- Trial name
- NCT01798225
- Testing
- Doxycycline
- Volunteers
- 113 people
- Sponsor
- Medical University of South Carolina
Sjögren Syndrome, Sicca Syndrome
N-acetylcysteine for Primary Sjögren's Syndrome
N-acetylcysteine (NAC) allows the elimination of reactive oxygen species (ROSs) and it has an anti-inflammatory effect. For this reason, NAC has been used and researched for treatment of several diseases, such as autoimmune…
- Trial name
- NACSS (NCT04793646)
- Testing
- N-acetylcysteine syrup
- Where
- 2 sites in Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
HIV (Human Immunodeficiency Virus), AIDS
Disease Evolution and Risk Factors of AIDS-related Prevalent Cancers
This study aims to investigate the disease progression trends and risk factors of common AIDS-related tumors, including Kaposi sarcoma, lymphoma, lung cancer, and et al., among people living with HIV.
- Conditions
- HIV (Human Immunodeficiency Virus), AIDS, Kaposi Sarcoma (KS), Lymphoma
- Trial name
- NCT07696169
- Volunteers
- 1,000 people
- Sponsor
- Shenzhen Third People's Hospital
Sjogren's Syndrome
Sex Steroids in Sjögren's Syndrome: Effect of Substitution Treatment on Fatigue
Our research contributes to the understanding of some of the basic biology of the salivary glands. The etiology and many of the pathomechanisms of Sjögren's syndrome are unknown.
- Trial name
- NCT00543166
- Testing
- dehydroepiandrosterone
- Where
- Finland
- Volunteers
- 107 people
- Sponsor
- University of Helsinki
Colorectal Cancer, Triple Negative Breast Cancer
Haplo / Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted γδ T Cells for Relapsed or Refractory Solid Tumour
This clinical trial is an open-label, single-centre, dose escalation, phase I study designed to investigate the safety and tolerability of Haploidentical / Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted Gamma Delta…
- Conditions
- Colorectal Cancer, Triple Negative Breast Cancer, Sarcoma, Nasopharyngeal Carcinoma
- Trial name
- NCT04107142
- Testing
- Adoptive Cell Transfer of NKG2DL-targetting Chimeric Antigen Receptor-grafted Gamma Delta T cell
- Where
- Malaysia
- Volunteers
- 10 people
- Sponsor
- CytoMed Therapeutics Pte Ltd
Bell's Palsy
Efficacy of Laser Acupuncture for Idiopathic Bell's Palsy
Objective: Bell's palsy is characterized by acute, unilateral onset that compromises function and esthetics, exerting a considerable impact on the social, professional, and psychological aspects of the lives of affected…
- Trial name
- NCT06280794
- Testing
- Laser acupuncture, Steroids
- Where
- China
- Volunteers
- 336 people
- Sponsor
- Beijing Tongren Hospital
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