Clinical trials: Stomatognathic System
Gingivitis; Chronic
Effects of Using Miswak in Addition to Oral Hygiene Products in Patients With Gingivitis
This pilot study aims to evaluate the effects of miswak use on the oral biological environment by comparing biochemical parameters obtained from saliva and dental plaque samples collected from individuals who use miswak and…
- Trial name
- NCT07689786
- Testing
- Miswak, Toothpaste
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Bladder Cancer, Cervical Cancer
Acceptability of Less Harmful Alternatives to Cigarettes
RATIONALE: A study that evaluates participants' beliefs about smokeless tobacco products and nicotine replacement therapy may be useful in helping smokers stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00957424
- Testing
- telephone-based intervention, nicotine replacement therapy, informational intervention
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Roswell Park Cancer Institute
Oral Mucositis
Impact of the Use of Zinc in the Prevention of Oral Mucositis in Pediatric Patients With Lymphoblastic Acute Leukemia.
Oral mucositis (OM) is a secondary complication of chemo/radiotherapy, which causes pain, dysphagia and predisposition to infections, being a frequent reason for hospitalization that may have an impact on the prognosis of cancer…
- Trial name
- NCT04321850
- Testing
- Zinc Sulfate 50 Mg Tab
- Where
- Mexico
- Volunteers
- 21 people
- Sponsor
- National Institute of Pediatrics, Mexico
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Systemic Sclerosis, Gougerot Sjogren Syndrome
Echo Systemic Sclerosis
Systemic sclerosis is an autoimmune connective tissue disease with undefined etiology and characterized by progressive fibrosis of the skin and major organs.
- Conditions
- Systemic Sclerosis, Gougerot Sjogren Syndrome, Sicca-Asthenia-Polyalgia Syndrome
- Trial name
- NCT03143413
- Testing
- Ultrasonography
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies
The purpose of this study is to identify genes associated with impaired development and function of the cranial nerves and brainstem, which may result in misalignment of the eyes (strabismus) and related conditions.
- Conditions
- Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome, Duane Radial Ray Syndrome, Mobius Syndrome
- Trial name
- NCT03059420
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Inferior Alveolar Nerve Injuries
Does Low-level Laser Therapy Protocol Affect the Efficacy of Treatment of Inferior Alveolar Nerve Injury After Maxillofacial Surgery
Dear Patient, Dear Parent / Guardian; This consent form has been prepared to enlighten you about the nature of the diagnosis and treatment methods that have been explained to you/patient and will be applied, the expected benefits…
- Trial name
- NCT06893497
- Testing
- Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Karadeniz Technical University
Temporomandibular Disorders
Stomatognathic System Assesment, After Different Methods of Establishing the Centric Relation
Patients with complete dentures were examined after the prosthoddontic treatment with two methods of establishing a centric relation: wax rims and gothic arch tracing method.
- Trial name
- NCT03343015
- Testing
- complete dentures
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Dental Malocclusion, Angle Class II
BRIUS Vs FFA Efficiency
The purpose of this study is to compare the Full Fixed Preadjusted appliances (regular braces) when to the BRIUS system.
- Conditions
- Dental Malocclusion, Angle Class II, Angle Class I, Crowding, Tooth
- Trial name
- NCT04347018
- Testing
- BRIUS
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Dysphagia, Head and Neck Cancer
Chemo/XRT +/- Amifostine to Assess Outcomes Related to Xerostomia, Mucositis, & Dysphagia
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells.
- Conditions
- Dysphagia, Head and Neck Cancer, Mucositis, Xerostomia
- Trial name
- NCT00503776
- Testing
- exercise intervention, amifostine trihydrate, therapeutic dietary intervention
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Mucositis, Chemotherapeutic Toxicity
The Efficacy and Safety of a Compound Glutamine Capsule in the Primary Prevention of Chemotherapy-induced Mucositis
Chemotherapy regimens not only improve the survival of patients with gastric cancer and colorectal cancer, but also cause obvious adverse reactions of digestive tract, such as chemotherapy-induced oral mucositis, abdominal pain…
- Trial name
- NCT05092113
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Meng Qiu
Facial Paralysis
Intraoperative Electrical Stimulation to Improve Nerve Grafting Outcome
A research study to find out if brief intraoperative electrical stimulation therapy improves nerve regeneration and smile outcomes following two-stage cross face nerve graft facial reanimation surgery.
- Trial name
- NCT06335719
- Testing
- BES, Standard of Care surgery
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Esophageal Cancer, Head and Neck Cancer
Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal Volunteers
RATIONALE: Studying samples of sputum and tissue in the laboratory from patients with dysplasia or cancer may help doctors identify and learn more about biomarkers related to cancer.
- Conditions
- Esophageal Cancer, Head and Neck Cancer, Lung Cancer, Precancerous Condition
- Trial name
- NCT00900419
- Testing
- immunohistochemistry staining method, laboratory biomarker analysis, sputum cytology
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- University of Colorado, Denver
Hypersalivation, Cerebral Palsy
Turkish Validation of The Drooling Impact Scale
The aim of this study is to investigate the reliability and construct validity of the Turkish version of the Drooling Impact Scale in children with cerebral palsy
- Trial name
- NCT04132765
- Testing
- Drooling Impact Scale, Drooling Frequency and Severity Scale, The Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD™)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Gingivitis, Plaque
Effectiveness of the GumChucks® Flossing System Compared to String Floss for Interdental Plaque Removal in Children
This study evaluates the interdental plaque removal efficacy, flossing speed, and reduction in gingival inflammation of a new flossing system (GumChucks®) compared to string floss, and to assess preference between the two…
- Trial name
- NCT04057430
- Testing
- GumChucks, String floss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Tooth Loss
A Clinical Study of the TSX Dental Implant System (Xpresso)
A prospective, observational, multicenter study where 62 patients needing implants in the maxilla or mandible will be enrolled. The patients will be restored with a final prosthesis no later than 4 months following implant…
- Trial name
- Xpresso (NCT06571812)
- Testing
- TSX
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- ZimVie
Tongue Cancer, Jaw Cancer
Quality of Life in Patients Treated for Tongue and/or Jaw Neoplasia Before and After Speech Therapy
This study aims to verify the impact of four speech therapy sessions on the Quality of Life of patients treated for malignant tongue and/or jaw cancer, using as measure specific questionnaires of speech and swallowing.
- Conditions
- Tongue Cancer, Jaw Cancer, Oral Cancer, Intelligibility, Speech
- Trial name
- NCT04126226
- Testing
- Speech-language guidance, Speech therapy exercises for swallowing, Speech therapy exercises for speech
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Diabetes Mellitus, Type 1, Periodontal Diseases
Periodontal and Salivary Evaluation of Type 1 Diabetes Mellitus Patients
Diabetes Mellitus is a risk factor for periodontal disease increasing its prevalence, extension and severity. Periodontal disease is considered the sixth complication of diabetes.
- Trial name
- NCT02935868
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Breast Cancer, Colorectal Cancer
Vaccine Therapy in Treating Patients With Advanced or Metastatic Cancer
RATIONALE: Vaccines made from a person's white blood cells that have been treated in the laboratory may make the body build an immune response to kill tumor cells.
- Conditions
- Breast Cancer, Colorectal Cancer, Gallbladder Cancer, Gastric Cancer
- Trial name
- NCT00027534
- Testing
- TRICOM-CEA(6D)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Michael Morse, MD
Molar Incisor Hypomineralisation, Enamel Hypoplasia
Effect of Resin Infiltration on Hypersensitivity and Satisfaction in Children With Enamel Defects
This study evaluates the effect of resin infiltration on dental sensitivity, quality of life, and satisfaction in children aged 7-14 with enamel defects in their front teeth.
- Conditions
- Molar Incisor Hypomineralisation, Enamel Hypoplasia, Dental Hypersensitivity
- Trial name
- NCT07118111
- Testing
- Resin infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gizem Tıraşçı
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