Clinical trials: Stomatognathic System
Dental Caries
Microbiological Evaluation and Clinical 24-month Follow-up of Adhesive Systems on Carious Dentin
The objectives were to evaluate the antibacterial effect of self-etching adhesives on carious dentin and the clinical results of restorations in a randomized controlled clinical trial.
- Trial name
- NCT05676671
- Testing
- Applications of self-etching adhesives and dental restorations
- Where
- Brazil
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Uveitis, Diabetic Retinopathy
Biomarkers of Common Eye Diseases
To identify biomarkers of common eye diseases based on single-cell sequencing technologies using PBMC samples. These diseases include uveitis, diabetic retinopathy, age-related macular degeneration and polypoid choroidal…
- Conditions
- Uveitis, Diabetic Retinopathy, Age-related Macular Degeneration, Polypoidal Choroidal Vasculopathy
- Trial name
- NCT04101604
- Testing
- Collection of blood samples
- Where
- China
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Acne, Bites
Implementation of a Minor Ailment Service in Community Pharmacy Practice
Self-care and self-medication are commonly the treatments of choice for the management of minor ailments. Minor ailments can be treated through community pharmacy using a Minor Ailment Service (MAS).
- Conditions
- Acne, Bites, Burns, Cold
- Trial name
- INDICA+PRO (NCT05247333)
- Testing
- Minor ailment service
- Where
- Spain
- Volunteers
- 20,987 people
- Sponsor
- Universidad de Granada
Trigeminal Neuralgia, Glossopharyngeal Neuralgia
Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia
The investigators will treat patients (targeting enrollment of n=20) who suffer from trigeminal or glossopharyngeal nerve pain in the context of painful small fiber neuropathy.
- Trial name
- NCT04158752
- Testing
- Galcanezumab
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Gingivitis, Diabetes
Mechanical-chemical Gingival Therapy in Diabetics and/or Obese
Diabetes and obesity affect many people in different countries. Similarly, millions of people have some type of gum disease such as gingivitis.
- Conditions
- Gingivitis, Diabetes, Obesity
- Trial name
- MCGTDO (NCT02123563)
- Testing
- Ultrason Essential oils rinse
- Where
- Brazil
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Taubate
Cleft Lip and Palate
Otologic and Rhinologic Outcomes in Children With Clef Palate
OBJECTIVE: To compare otologic and rhinologic outcomes in patients with cleft palate according to surgical protocols and type of cleft. DESIGN: Monocentric retrospective and prospective analysis of medical reports.
- Trial name
- Clef Palate (NCT03708406)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of…
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Head and Neck Cancer, Kidney Cancer
- Trial name
- NCT00005952
- Testing
- filgrastim, temozolomide, peripheral blood stem cell transplantation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Bruxism, Sleep
Efficacy of Botulinum Toxin and Marjoram Oil Applications in Bruxism
Objective: Bruxism is defined as clenching or grinding teeth unconsciously. It can be categorized under two subheadings: sleep and awake bruxism.
- Trial name
- NCT06674733
- Testing
- Botox administration, Aromatherapy, Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Bezmialem Vakif University
Tooth-loss
Occlusal Relationship Assesment of Monolithic Zirconia FDPs
To analyze in vivo occlusal accuracy and occlusal adjustment requirement, a cross-over clinical trial was designed. Two 3-unit tooth-supported posterior FDPs were planned to be made for each patient's single missing tooth gap…
- Trial name
- NCT04855084
- Testing
- Monolithic FDPs: before adjustment, Monolithic FDPs: after adjustment, Metal fused porcelain FDPs: before adjustment
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duygu Karasan
Jaw Abnormalities
A Modified Minimally Invasive Approach Towards Le Fort I Osteotomy: a Prospective Study
Nowadays, maxillary Le Fort I osteotomy is a safe and routinely performed procedure. The conventional approach is characterized by a vestibular incision extending from molar-to-molar, associated with a pterygomaxillary…
- Trial name
- MILF-I (NCT02660216)
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- AZ Sint-Jan AV
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Laryngeal Injuries
Laryngeal Injuries After Anesthesia Induction With Sevoflurane and After Anesthesia Induction With Rocuronium
Anesthesia induction with sevoflurane is not associated with an increased incidence or severity of laryngeal injuries compared with an anesthesia induction with a muscle relaxant.
- Trial name
- NCT01591031
- Testing
- Sevoflurane, Rocuronium
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Rostock
Trigeminal Neuralgia
Management of Arachnoid Nerve Tethering in Trigeminal Neuralagia
This study aims to evaluate the clinical significance of arachnoid-trigeminal nerve conflict in patients with medically refractory trigeminal neuralgia without demonstrable neurovascular conflict on preoperative magnetic…
- Trial name
- NCT07811973
- Testing
- Arachnoid nerve detethering
- Volunteers
- 23 people
- Sponsor
- Assiut University
Hypomineralization of Enamel
PMCs as a Treatment of Children With HSPM Using the HT
Hypomineralised primary second molars are primary molars with a developmental disorder of the enamel. Preformed metal crowns already have good results for the treatment of caries on primary molars.
- Trial name
- NCT04265183
- Testing
- Placing preformed metal crowns using Hall technique.
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cochlear Hearing Loss, Hearing Loss, Sensorineural
Minimizing Facial Nerve Stimulation in Cochlear Implants
This study aims to understand how to manipulate the electrical stimulation from the cochlear implant to maximize hearing stimulation and minimize facial stimulation.
- Conditions
- Cochlear Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Facial Nerve Injury
- Trial name
- NCT04161261
- Testing
- Electrical Stimulation
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Dental Implants, TNF-alpha Inhibitors
Dental Implant Healing With TNF-Alpha Inhibitors
The goal of this pilot study is to learn about healing after dental implant placement in patients taking a class of biologic drug called Tumor Necrosis Factor or TNF-alpha antagonist or inhibitor.
- Conditions
- Dental Implants, TNF-alpha Inhibitors, Edentulism
- Trial name
- NCT06538870
- Testing
- Placement of dental implants
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Oral Squamous Cell Carcinoma, Oropharynx Squamous Cell Carcinoma
Detection of Oral and Throat Cancers Using OralViome Cancer Testing System
To evaluate the design, safety and efficacy of OralViome Cancer Testing system in the early detection of Oral and Throat Cancers using saliva metatranscriptomic analysis.
- Conditions
- Oral Squamous Cell Carcinoma, Oropharynx Squamous Cell Carcinoma, Premalignant Lesion
- Trial name
- NCT05451303
- Testing
- OralViome Cancer Testing System
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Viome
Pulpitis
Efficacy of Oral Prednisolone on Pain Reduction in Emergency Care of Acute Irreversible Pulpitis
Irreversible pulpitis is an inflammatory condition of the dental pulp, highly painful, representing one of the main reasons for consulting dental emergency.
- Trial name
- PULPISOLONE (NCT02629042)
- Testing
- Partial endodontic treatment under local and/or locoregional anesthesia, prednisolone
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Bordeaux
Urologic Diseases, Gastrointestinal Diseases
PACT Programme for Parents of Children With SHCN
This randomised controlled trial aims to determine the efficacy of a 12-week, smartphone-based Prosocial-orientated Acceptance and Commitment Training (PACT) programme plus age-appropriate positive parenting advice on the…
- Conditions
- Urologic Diseases, Gastrointestinal Diseases, Vascular Diseases, Cleft Lip and Palate
- Trial name
- NCT05467527
- Testing
- Prosocial-orientated Acceptance and Commitment Training plus positive parenting advice, Positive parenting advice
- Where
- 2 sites in Hong Kong
- Volunteers
- 196 people
- Sponsor
- Chinese University of Hong Kong
Edentulous Jaw
A Clinical Study of the TSV Dental Implant System
This will be a prospective, randomized, observational study. All implants will be placed in either the maxilla or mandible and loaded within 2 months with a provisional or definitive prosthesis.
- Trial name
- Blue Sky (NCT04236336)
- Testing
- TSV dental implant
- Where
- 5 sites in United States, Spain
- Volunteers
- 104 people
- Sponsor
- ZimVie
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.