Clinical trials: Stomatognathic System
Molar Incisor Hypomineralisation
Correlation Between Colour and Hypersensitivity of First Permanent Molars With Molar Incisor Hypomineralisation (MIH)
Cheese molars (MIH: molar incisor hypomineralisation) can be recognized not only by their colour abnormalities but also by their hypersensitivity.
- Trial name
- NCT07727044
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Basel
Mandibular Hypoplasia
Juvederm Voluma® XC for the Treatment of Hypoplastic Chin
This is a single center study of the safety and efficacy of Juvedérm Voluma for the treatment of hypognathism. Each qualified subject will undergo treatment with Juvedérm Voluma in the anterior and lateral chin for volume…
- Trial name
- VolumaChin (NCT02330016)
- Testing
- Voluma XC
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kenneth Beer
Covid19, Nasopharyngitis
BNO 1030 Extract (Imupret) in the Treatment of Mild Forms of COVID-19
According to WHO (World Health Organisation) data, about 40% of patients with COVID-19 (Corona Virus SARS-CoV-2) have a mild course of the disease, namely, cases of mild course are of great danger from the point of view of the…
- Conditions
- Covid19, Nasopharyngitis, Anosmia, Fever
- Trial name
- NCT04797936
- Testing
- BNO 1030, Standard care
- Where
- Ukraine
- Volunteers
- 133 people
- Sponsor
- Ivano-Frankivsk National Medical University
Sjogren's Syndrome
Evaluation of FID 114657 in Sjogren's Syndrome Subjects
The primary objective of this study is to assess the overall Sjogren's Syndrome subject's preference for a particular product. Dry eye symptom relief will also be evaluated based on clinical evaluation and a set of subject…
- Trial name
- NCT01079871
- Testing
- FID 114657 (ORB Preserved Ocular Emulsion)
- Volunteers
- 50 people
- Sponsor
- Alcon Research
Bullous Keratopathy, Corneal Erosion
AONDA Therapeutic Indication Study I
This study will be used to support assessment of AIR OPTIX® NIGHT \& DAY® AQUA (AONDA) Soft Contact Lenses' safety and performance in accordance with updated European Union Medical Device Regulation (EU MDR) requirements.
- Conditions
- Bullous Keratopathy, Corneal Erosion, Entropion, Corneal Edema
- Trial name
- NCT05891106
- Testing
- Lotrafilcon A contact lenses
- Where
- 3 sites in United States
- Volunteers
- 55 people
- Sponsor
- Alcon Research
Dentofacial Deformities, Le Fort; I
Comparison Between Two Techniques to Reposition the Maxilla After le Fort 1
clinical and radiographic comparison between novel locating guide design with pre-bent titanium plates and 3d printed intermediate wafer to reposition the maxilla after Le Fort 1 osteotomy in orthognathic surgery (randomized…
- Trial name
- orthognathic (NCT06132906)
- Testing
- Orthognathic surgery (lefort1)
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dental Fluorosis
Presence of Enamel Fluorosis in Libyan Children
Fluorosis is caused by hypomineralization in the enamel due to increased fluoride ingestion during early childhood (Cawson.1, Wong et al. 2, and Sudhir 3).
- Trial name
- NCT03746990
- Volunteers
- 1,935 people, healthy volunteers welcome
- Sponsor
- Ajman University
Hemifacial Spasm, Intraocular Pressure
Effect of Hemifacial Spasm on Intraocular Pressure Measurement
Twenty-four consecutive patients with Hemifacial spasm and 25 age and gender-matched randomly selected eyes of healthy volunteers underwent corneal pachymetry and intraocular pressure measurements using Goldmann Applanation…
- Trial name
- NCT03390803
- Testing
- effect of hemifacial spasm on intraocular pressure
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Medipol University
Vocal Cord; Injury, Superficial
Laryngeal Injuries After Removal of the Tracheal Tube: A Comparison Between Sevoflurane and Propofol
Vocal cord injuries occur not only during tracheal intubation, but also during surgery and during removal of tracheal tube. Volatile anesthetics increase neuromuscular block of muscle relaxants.
- Trial name
- NCT01616966
- Testing
- Sevoflurane, propofol
- Where
- Germany
- Volunteers
- 65 people
- Sponsor
- University of Rostock
Oral Disease, Stroke, Ischemic
Oral Health in Patients Hospitalized Because of Ischemic Stroke
Maintaining good oral health is essential for general health and quality of life. Results of many anal-yses showed that stroke patients had poorer oral condition and worse periodontal status than control population.
- Trial name
- NCT06332846
- Testing
- oral examination
- Where
- Poland
- Volunteers
- 118 people
- Sponsor
- Pomeranian Medical University Szczecin
Trigeminal Neuralgia
Effect of Non-invasive Photobiomodulation Therapies in Patients With Trigeminal Neuralgia
The aim of this study was to compare the effectiveness of two different photobiomodulation (PBM) therapies as an alternative to medical treatment to reduce pain and improve quality of life in patients with trigeminal neuralgia…
- Trial name
- NCT06440356
- Testing
- laser therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Sleep Bruxism, Airway Remodeling
Physiotherapy on the Airway of Bruxist Children
Objective: to evaluate the effects of physiotherapy on the anteroposterior airway size in a group of bruxist children Question: Is a physiotherapeutic technique aiming at changing the head posture, effective to increase the…
- Conditions
- Sleep Bruxism, Airway Remodeling, Physical Therapy Modalities
- Trial name
- NCT01178229
- Testing
- Physiotherapy
- Where
- Colombia
- Volunteers
- 26 people
- Sponsor
- CES University
Primary Sjögren's Syndrome
Safety, Pharmacokinetics and Preliminary Efficacy Study of CFZ533 in Patients With Primary Sjögren's Syndrome
This study did evaluate the safety,tolerability and preliminary therapeutic efficacy of multiple doses of intravenous infusion of CFZ533 monoclonal antibody in patients with primary Sjögren's syndrome(pSS)
- Trial name
- NCT02291029
- Testing
- CFZ533 active - Cohort 1, CFZ533 active - Cohort 2, CFZ533 active -Cohort 3
- Where
- 9 sites in United States, Germany and 3 more
- Volunteers
- 69 people
- Sponsor
- Novartis Pharmaceuticals
Malocclusion
Class II Correction Study Using the Invisalign System
To demonstrate that growing teenagers which present up to full cusp Class II malocclusions can be treated using the Invisalign System.
- Trial name
- NCT02376829
- Testing
- Invisalign System
- Where
- 10 sites in United States, Canada
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Align Technology, Inc.
Mucosal Inflammation, Contraceptive; Complications, Intrauterine
Impact of Contraceptives on Cervico-Vaginal Mucosa
UMPALA is a research study to look at the effect of four different, approved contraceptives on the cervical and vaginal tissues as well as on factors in the blood.
- Trial name
- UMPALA (NCT04814927)
- Testing
- Copper IUD, Etonogestrel implant, Levonorgestrel IUS
- Where
- 2 sites in United States, Kenya
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Trigeminal Neuralgia
Efficacy and Safety of Irregular Pulsed Radiofrequency (Sluijter-Teixera Poisson) Versus Regular Pulsed Radiofrequency to the Gasserian Ganglion for Treatment of Primary Trigeminal Neuralgia
This study aims to compare between the Efficacy and safety of irregular pulsed radiofrequency STP versus regular pulsed radiofrequency to the gasserian ganglion for treatment of primary trigeminal neuralgia.
- Trial name
- NCT07275229
- Testing
- Irregular pulsed Radiofrequency, Regular pulsed Radiofrequency
- Volunteers
- 62 people
- Sponsor
- Sohag University
Malocclusion, Malocclusion; Displaced or Missing Teeth
Effectiveness of Auxiliary Segmental Lingual Appliances in Leveling the Curve of Wilson at Second Molars
This study aims to evaluate the effectiveness of auxiliary segmental lingual appliances in leveling the Curve of Wilson at the second molars in patients undergoing labial fixed orthodontic treatment.
- Conditions
- Malocclusion, Malocclusion; Displaced or Missing Teeth, Malocclusions, Orthodontic Treatment
- Trial name
- EASLALCW (NCT06858670)
- Testing
- Auxiliary Segmental Lingual Appliances
- Where
- Vietnam
- Sponsor
- Hanoi Medical University
Stevens-Johnson Syndrome
Corneal Epitheliotropic Factors in Autologous Serum Eye Drops in Nonautoimmune and Stevens-Johnson Syndrome With Dry Eye
Autologous serum eye drops (ASE) have been becoming popular in treatment of severe dry eye for the past decade. One of the most beneficial properties of the ASE over artificial eye drops is the epitheliotropic capacity owing to…
- Trial name
- NCT01122303
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Pain, Postoperative, Endodontically Treated Teeth
Postoperative Pain Intensity Associated With the Use of Different Nickel Titanium Instrumentation Systems
In this study the effect of different engine-driven nickel titanium (Ni-Ti) instrumentation systems (OneShape, Revo S and WaveOne) on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root…
- Trial name
- NCT03478241
- Testing
- Group 1: single file rotary motion, Group 2: multiple file rotary motion, Group 3: single file reciprocal motion
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Stevens-Johnson Syndrome, Toxic Epidermal Necrolyses
NATIENS: Optimal Management and Mechanisms of SJS/TEN
The North American Therapeutics in Epidermal Necrolysis Syndrome (NATIENS) study is a multicenter double-blind randomized controlled assessment of two arms - one of systemic immunomodulatory therapy (etanercept) and one of…
- Trial name
- NATIENS (NCT02987257)
- Testing
- Harmonized supportive care, Etanercept 50 mg sc day 1 and day 4
- Where
- 14 sites in United States
- Volunteers
- 2 people
- Sponsor
- Vanderbilt University Medical Center
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