Clinical trials: Stomatognathic System
Muscle Pain, Feedback, Psychological
Evaluation of Biofeedback Therapy Efficiency in Masticatory Muscles Pain Management
This study evaluates beneficial effects of biofeedback therapy in reducing pain and increased tension of muscles occurring in patients with temporomandibular disorders (TMD).
- Conditions
- Muscle Pain, Feedback, Psychological, Craniomandibular Disorders, Temporomandibular Disorder
- Trial name
- NCT03421028
- Testing
- Electromyography Biofeedback, Classic treatment for myogenous TMD
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw Medical University
Pain, Postoperative, Endodontically Treated Teeth
Post-Endodontic Instrumentation Pain After in a Single Session Associated With Photobiomodulation
The objective of this double-blind, randomized controlled clinical study will be to evaluate the effect f PBM on pain after endodontic instrumentation in the single-session treatment of upper molars and premolars.
- Trial name
- NCT06253767
- Testing
- Endodontic Treatment, Low Level Laser Therapy, Simulation Low Level Laser therapy
- Where
- Brazil
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Penetrating Keratoplasty, Multiple Graft Failure
Subconjunctival Humira for Boston Keratoprosthesis
This trial is studying the safety and tolerability of receiving an injection of adalimumab (Humira) during the Boston Keratoprosthesis (KPro) surgery.
- Conditions
- Penetrating Keratoplasty, Multiple Graft Failure, Ocular Cicatricial Pemphigoid, Stevens-Johnson Syndrome
- Trial name
- NCT06926478
- Testing
- Adalimumab Injection
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Diabetic Retinopathy, Periodontitis
Periodontitis Severity in Patients With Diabetic Retinopathy
The aim of this observational study is to investigate the relationship between periodontal disease severity and retinal layer thickness in patients diagnosed with diabetic retinopathy (DR), using optical coherence tomography…
- Trial name
- NCT07137013
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Facial Paralysis
Outcome of Facial Palsy Following Rehabilitation
Retrospective case series,the aim of this study is to assess the outcome and rate of complications in patients with facial palsy following rehabilitation, a retrospective study.
- Trial name
- NCT04215562
- Testing
- rehabilitation
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- University of Alexandria
Mowat-Wilson Syndrome, Dental Caries
Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study.
Mowat-Wilson Syndrome (MWS) is a rare syndrome characterized by the presence of facial gestalt and delayed psychomotor development, variably associated with intellectual disability, epilepsy, Hirschsprung's disease (HSCR) and…
- Conditions
- Mowat-Wilson Syndrome, Dental Caries, Periodontal Diseases, Sleep Related Breathing Disorder
- Trial name
- ORALMOWAT26 (NCT07476417)
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Milan
Temporomandibular Disorder (TMD)
Marine Lipids Ease Painful TMD
The ADAPT study is a single-site, Phase 2b, randomized, quadruple-masked, placebo-controlled trial evaluating an omega-3 dietary supplement enriched with specialized pro-resolving mediator (SPM) precursors in adults with chronic…
- Trial name
- ADAPT (NCT07437313)
- Testing
- SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Head and Neck Cancer, Mucositis
Magic Mouthwash Plus Sucralfate Versus Benzydamine Hydrochloride for the Treatment of Radiation-induced Mucositis
Radiation treatment is very effective for treating cancers of the head and neck, however, during the course of treatment, it is common for patients to experience soreness of their mouth and throat due to the radiation.
- Trial name
- NCT00814359
- Testing
- Combination of Magic Mouthwash Plus Sucralfate, 0.15% Benzydamine HCl
- Where
- Canada
- Volunteers
- 67 people
- Sponsor
- Juravinski Cancer Centre Foundation
Sjogren Syndrome
Cross-sectional Study of Use of Speckle Method in Early Diagnosis of Cardiovascular Dysfunction
Speckle tracking (STE) is a novel echocardiographic technique which permits calculation of myocardial velocities and deformation parameters such as strain and strain rate (SR).
- Trial name
- SPEEDCARS (NCT02132585)
- Testing
- Speckle tracking echocardiography
- Where
- 2 sites in Italy
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Type 1 Diabetes, Periodontitis
Type I Diabetes and Non-surgical Periodontal Treatment
Current evidence suggests a bidirectional association between periodontitis and diabetes. Periodontal therapy improves short term HbA1c levels and is safe to perform. Most studies are focused on type 2 Diabetes.
- Conditions
- Type 1 Diabetes, Periodontitis, Periodontal Diseases, Diabetes
- Trial name
- NCT05569525
- Testing
- Non-surgical periodontal therapy
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Florence
Bell Palsy
Combined Effects of Low Level Laser Therapy and Kabat Technique in Patients With Bell's Palsy
The objective of this current study is to determine the combined effects of Low-Level Laser Therapy (LLLT) and the Kabat technique on quality of life, synkinetic movements and functional outcome in patients of Bell's palsy
- Trial name
- NCT06028191
- Testing
- Kabat Technique along with baseline treatment, Kabat Technique and LLLT along with baseline treatment
- Where
- 2 sites in Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Maxillary Deficiency, Head and Neck Neoplasms
Predictors of Patient-Reported Outcomes for Maxillectomy Patients
The success of digitally fabricated obturator rehabilitation is determined not only by the prosthesis itself but also by the interaction between patient characteristics, oncologic history, prosthetic support, and…
- Trial name
- NCT07864974
- Testing
- Digitally Fabricated Obturator Prosthesis
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dr. Merve Benli
Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis (Lyell) Syndrome
Topical Infliximab in Autoimmune Eyes With Keratoprosthesis
The Boston Keratoprosthesis type I (KPro) is a prosthetic cornea used to treat several causes of corneal blindness. Some categories of patients, including those with auto-immune diseases such as Stevens-Johnson syndrome, toxic…
- Conditions
- Stevens-Johnson Syndrome, Toxic Epidermal Necrolysis (Lyell) Syndrome, Mucous Membrane Pemphigoid
- Trial name
- NCT02126020
- Testing
- topical infliximab
- Where
- 2 sites in United States, Canada
- Sponsor
- James Chodosh, MD, MPH
Myofacial Pain Syndromes
Evaluation of 3D Michigan Appliance
20 patients will be divided into 2 groups Group 1 : in which conventional appliance will be constructed after alginate impression Group 2 : in which 3d printed appliance will be constructed after intra-oral scanning
- Trial name
- NCT05959174
- Testing
- 3D printed mitchigen appliance, side chair appliance
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Fayoum University
Periapical Abscess
Comparison of Two Combinations of Opioid and Non-opioid Analgesics for Acute Periradicular Abscess
Aim: The aim of this study was to compare the analgesic efficacy of two combinations of opioid and non-opioid analgesics for acute periradicular abscesses.
- Trial name
- NCT02750696
- Testing
- Fixed-dose oral tablet of codeine/ acetaminophen every 4 hours for 3 days, Fixed-dose oral tablet of tramadol/ acetaminophen every 4 hours for 3 days
- Volunteers
- 27 people
- Sponsor
- Federal University of Rio Grande do Sul
Sjogren's Syndrome
Sjogrens Syndrome Measured by Ultrasound
Ultrasound study focused on salivary gland outcomes in Sjogren's subjects
- Trial name
- NCT03411850
- Testing
- Orencia
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arthritis & Rheumatism Associates, P.C.
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Orofacial Clefts, Cleft Lip and Palate
Analgosedation With Ketamine, Nalbuphine, or Dexmedetomidine for Suture Removal in Children After Cleft Surgery
This prospective, randomized study is designed to compare the efficacy and safety of three sedative-analgesic agents-intramuscular ketamine, intranasal nalbuphine, and intranasal dexmedetomidine-for procedural sedation in…
- Conditions
- Orofacial Clefts, Cleft Lip and Palate, Alveolar Ridge Defect
- Trial name
- KID-CLEFT (NCT07340008)
- Testing
- ketamine, Nalbuphine, Dexmedetomidine
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- University Medical Centre Ljubljana
Keratoconus, Ocular Surface Disease
Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting
EYEdeal Scanning Technology enables rapid measurement of corneal and scleral topography. By accurately measuring the ocular surface with this imaging technology, the current iterative fitting method required to fit PROSE…
- Conditions
- Keratoconus, Ocular Surface Disease, Pellucid Marginal Corneal Degeneration, Ectasia
- Trial name
- NCT04649177
- Testing
- Ocular surface optical coherence tomography
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Oropharyngeal Dysphagia, Oropharyngeal Cancer
Respiratory-Swallow Training in Veterans With Oropharyngeal Cancer
Cancers of the head and neck require surgical, radiation, and chemotherapy treatments that are intended to cure the disease. These treatments have toxic effects on muscles and structures that are necessary to swallow safely and…
- Trial name
- RSPT (NCT01032928)
- Testing
- Respiratory-Swallow Phase training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- US Department of Veterans Affairs
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