Clinical trials: Stool Assessment, active
Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis), Inflamatory Bowel Disease
Physical Activity and Fitness in Pediatric Inflammatory Bowel Disease
Pediatric inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is a chronic condition associated not only with intestinal inflammation but also with reduced physical fitness, fatigue, impaired…
- Trial name
- PAFIT-IBD (NCT07484620)
- Testing
- Physical Activity Intervention
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid
Emerging Infectious Diseases, Communicable Diseases
Establishment of a Biobank for the Evaluation of Rapid Diagnostic Solutions
This multicenter prospective registry aims to establish a biobank of residual biological samples and associated clinical data from hospitalized patients.
- Conditions
- Emerging Infectious Diseases, Communicable Diseases, Biological Warfare Agents, Zoonoses
- Trial name
- NCT07411729
- Where
- 10 sites in France
- Volunteers
- 800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Oxidative Stress, Healthy
A Randomized, Double-Blind Study to Assess the Effect of a Postbiotic on Oxidative Stress and Exercise Performance
This is a prospective, randomized, placebo controlled, double-blind study to assess the effects of a postbiotic blend on exercise induced oxidative stress markers and exercise performance in healthy adult.
- Conditions
- Oxidative Stress, Healthy, Exercise-induced Muscle Damage, Exercise-induced Muscle Soreness
- Trial name
- PBE (NCT06795425)
- Testing
- Postbiotic Active Lifestyle Blend
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Cholangitis Acute, Recurrence
Fecal Microbiota Transplant vs Standard Treatment for Recurrent Non-Obstructive Cholangitis
Patients with abnormalities of the biliary tract (the system that connects the liver to the small intestine and allows bile to flow) are prone to the development of strictures, dilations, or other problems that impede bile flow…
- Trial name
- COLANBIOTA (NCT07509346)
- Testing
- Fecal Microbial Transplantation
- Volunteers
- 44 people
- Sponsor
- Puerta de Hierro University Hospital
Colorectal Cancer
Polyprev: Study to Compare Fecal Immunochemical Test With Endoscopic Surveillance After Advanced Adenoma Resection in Fecal Immunochemical Test Colorectal Cancer Screening Programs.
Colorectal cancer (CRC) screening programs have been implemented to reduce the burden of the disease. When an advanced colonic lesions is detected, it is recommended to perform endoscopic surveillance with different intervals…
- Trial name
- NCT04967183
- Testing
- Annual FIT, Endoscopic surveillance.
- Where
- Spain
- Volunteers
- 3,788 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Infantile Colic, Gastroesophageal Reflux (GER)
BioAmicus Complete for Functional Gastrointestinal Symptoms in Infants Aged 0 to 24 Months
Infants often experience functional gastrointestinal symptoms (e.g., colic, excessive gas, regurgitation, constipation, or loose stools) that distress families and may reflect an imbalance of the gut microbiome.
- Conditions
- Infantile Colic, Gastroesophageal Reflux (GER), Functional Constipation, Functional Diarrhea
- Trial name
- CTBE2503 (NCT07148583)
- Testing
- BioAmicus Complete, Usual Care (No Probiotic)
- Where
- Vietnam
- Volunteers
- 110 people
- Sponsor
- Haiphong University of Medicine and Pharmacy
Irritable Bowel Syndrome (IBS)
IBS-Oriented CDED Versus Low FODMAP Diet for Irritable Bowel Syndrome
Background: Irritable Bowel Syndrome (IBS) affects approximately 4.1% of the global population and imposes a significant personal and healthcare burden.
- Trial name
- IBS-CDED (NCT07707635)
- Testing
- Modified Crohn's Disease Exclusion Diet (CDED), Low FODMAP Diet
- Volunteers
- 150 people
- Sponsor
- Ariel University
Gastric Cancer, Colorectal Cancer
Evaluation of Fecal Multi-target Biomarkers in the Screening of Digestive Tract Cancers
This study is a multi-center, observational study. Participants scheduled for gastroscopy and colonoscopy will undergo an epidemiological assessment and provide a stool sample prior to endoscopy for qualitative Fecal…
- Trial name
- NCT07600125
- Testing
- Qualitative Fecal Immunochemical Test (FIT), quantitative (FIT), and testing for new biomarkers
- Where
- 13 sites in China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Crohn Disease
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Crohn Disease
Dysbiosis can be rectified by several methods: antibiotics, prebiotics, probiotics, dietary modulation, and fecal microbiota transplantation.
- Trial name
- ALTER-CD (NCT06890650)
- Testing
- Fecal Microbial Transplantation, Crohns disease exclusion diet
- Where
- 6 sites in India
- Volunteers
- 168 people
- Sponsor
- All India Institute of Medical Sciences
Normal Subjects, Fecal Incontinence
Trial to Evaluate Fecobionics in Fecal Incontinence (FI) (NORMAL and ABNORMAL-FI)
The objective is to determine the length-tension properties of the anal sphincters using Fecobionics in normal subjects and FI patients during anal distension and during simulated evacuation.
- Trial name
- NCT05412069
- Testing
- Fecobionics
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- The California Medical Innovations Institute, Inc.
Irritable Bowel Syndrome, Diarrhea-Predominant (IBS-D), Recurrent Clostridioides Difficile Infection (rCDI)
A Flexible Clinical Trial to Test if Freeze-dried Fecal Microbiota Therapy Helps Treat Diarrhea-predominant Irritable Bowel Syndrome or Prevent Recurring C. Difficile Infections.
The goal of this clinical trial is to learn if oral lyophilized fecal microbiota therapy (ORAL-LYO-FMT) helps treat diarrhea-predominant irritable bowel syndrome (IBS-D) and prevent the recurrence of Clostridioides difficile…
- Conditions
- Irritable Bowel Syndrome, Diarrhea-Predominant (IBS-D), Recurrent Clostridioides Difficile Infection (rCDI), Fecal Microbiota Therapy (FMT), Irritable Bowel Syndrome (IBS)
- Trial name
- ORAL-LYO-FMT (NCT06948461)
- Testing
- ORAL-LYO-FMT
- Volunteers
- 63 people
- Sponsor
- PharmaPlanter Technologies Inc
Colorectal Cancer (Diagnosis)
Secondary Care Colorectal Cancer Pathway Review
Bowel cancer (colorectal cancer) is the 4th most common cancer in Scotland. Approximately 4,000 cases are diagnosed annually. Cancer-related deaths in Scotland are higher than other UK nations.
- Trial name
- NCT07430527
- Testing
- Faecal Immunohistochemical test
- Where
- 2 sites in United Kingdom
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Gut Dysbiosis for TMAO Production From Red Meat Consumption
Development of Microbial Metabolism Gene Tests for Facilitating Precision Health and Preventive Medicine-Evaluation of TMAO Production in Human Body From High-carnitine Diet by Fecal Gbu Gene Testing
The risk of cardiovascular diseases from red meat consumption varies among individuals due to variations in gut microbiota. L-carnitine in red meat can be converted to Trimethylamine n-oxide (TMAO) in the body by certain…
- Trial name
- NCT07322575
- Testing
- Beef
- Where
- Taiwan
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
All Solid Tumors
Feasibility Study of MET-4: Evaluating Fecal Microbiome Effects in Immunotherapy Patients
This study is designed to assess the safety, tolerability and engraftment (cumulative relative abundance) of MET-4 strains when given in combination with immune checkpoint inhibitors (ICIs).
- Trial name
- MET4-IO (NCT03686202)
- Testing
- MET-4
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University Health Network, Toronto
Crohns Disease
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Crohn Disease on Advanced Therapies
Advanced therapies including biologics and small molecules target specific inflammatory pathways. IBD's multifactorial etiology means that blocking a single pathway may not be sufficient for all patients.
- Trial name
- BOOST-CD (NCT06890637)
- Testing
- Fecal Microbial Transplantation, Crohns Disease Exclusion Diet, Advanced therapy
- Where
- 6 sites in India
- Volunteers
- 168 people
- Sponsor
- All India Institute of Medical Sciences
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Patch Electrode
UCon is a medical device for treating the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behavior of the bladder/bowel musculature e.g.…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Nocturia, Urinary Frequency More Than Once at Night
- Trial name
- NCT06754189
- Testing
- Time Limited stimulation
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- InnoCon Medical
Irritation; Anus
Validation of TRansanal Irrigation Adherence scaLe (TRIAL)
Transanal irrigation (TAI) is a method used to empty stools from the recto-sigmoid and colon (from the descending colon to the transverse colon).
- Trial name
- NCT06805903
- Testing
- TRansanal Irrigation Adherence scaLe
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obese Patients, Obese Patients With Bariatric Surgery
Bariatric Surgery and Gut Microbiota Changes Over Time
The goal of this observational study is to learn how bariatric surgery affects gut bacteria and gut-related metabolic products over time in adults with obesity.
- Conditions
- Obese Patients, Obese Patients With Bariatric Surgery, Gut Microbiota, Healthy Participants
- Trial name
- RYGB-MICROGUT (NCT07381140)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Necrotizing Enterocolitis (NEC), Necrotizing Enterocolitis of Newborn
Fecal Microbiota Transplantation (FMT) as a Prophylaxis of Necrotizing Enterocolitis (NEC) - Clinical Study
The aim of the study is to assess the safety of fecal microbiota transplantation (FMT) as a preventive method for the development of Necrotizing enterocolitis (NEC) in a group of premature infants.
- Trial name
- NCT06333405
- Testing
- Fecal Microbiota Transplantation
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Medical University of Warsaw
Exercise, Overreaching
Impact of Training Load on the Gut miCrobiome And Its Relation to exeRcise Performance, mUscle Phenotype, and markerS of Overreaching in Healthy Men
The goal of this study is to learn how different amounts of supervised indoor cycling training change gut health (gut bacteria, the substances gut bacteria make, and the gut barrier integrity), and how these changes relate to…
- Conditions
- Exercise, Overreaching, Butyrate, Gut Microbiome
- Trial name
- ICARUS (NCT07481578)
- Testing
- Supplement, Moderate load exercise training, High load exercise training
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Stefan De Smet