Clinical trials: Strain
Heart Failure, Diastolic, Aortic Valve Stenosis
Changes in Cardiac Deformation Following Physiologic Alterations and Inotropic Support.
The investigators want to compare the effects of two drugs, levosimendan and milrinone, on cardiac muscle, both in terms of contractility and relaxation. Half of the participants will be randomized to each drug.
- Conditions
- Heart Failure, Diastolic, Aortic Valve Stenosis, Monitoring, Physiologic, Physiology
- Trial name
- NCT02408003
- Testing
- Levosimendan, Milrinone
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Sahlgrenska University Hospital
Athletic Injuries, Sprains and Strains
The Design and Evaluation of an Active Intervention for the Prevention of Non-contact ACL Injury
The overall goal of this project is to reduce the risk for anterior cruciate ligament injuries by designing a targeted intervention that will alter the known kinematic and kinetic risk factors associated with ACL injuries.
- Conditions
- Athletic Injuries, Sprains and Strains, Wounds and Injuries, Knee Injuries
- Trial name
- NCT01021111
- Testing
- Activity Training with Feedback
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Stanford University
Acute Pain From Ankle Sprain or Strain
An Efficacy and Safety Study for the Treatment of Mild to Moderate Acute Pain Associated With Ankle Strain or Sprain.
This is a randomized, double blind, placebo controlled, parallel group study to assess the efficacy and safety of K-103-IP compared with placebo patch for treatment of mild to moderate acute pain associated with ankle strain or…
- Trial name
- NCT02089425
- Testing
- K-103-IP
- Where
- 47 sites in United States
- Volunteers
- 384 people
- Sponsor
- Kowa Research Institute, Inc.
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Pain, Fracture, Sprain
Fentanyl Administered Intraorally for Rapid Treatment of Orthopedic Pain
Assess whether transbuccal fentanyl provides more rapid relief of orthopedic pain, than does the comparator Percocet
- Trial name
- FAIRTOP (NCT00685295)
- Testing
- Fentanyl, Lansoprazole, Oxycodone
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Decompensated Heart Failure
Speckle Tracking Echocardiography Adds Information in Decompensated Heart Failure
The overall objective of the study is to determine whether speckle tracking echocardiography presents additional prognostic value to the routine assessment (clinical and echocardiographic) in patients admitted with acute…
- Trial name
- STRAIN-DHF (NCT03009552)
- Testing
- speckle tracking echocardiography
- Where
- Brazil
- Volunteers
- 176 people
- Sponsor
- Marco Stephan Lofrano Alves
Suspected Infection With Vancomycin Susceptible Bacterial Strains
Pharmacokinetics of Vancomycin in ICU Patients
Vancomycin is frequently under-dosed in ICU patients during the first 24-48 hours of treatment. Glomerular hyperfiltration syndrome, increased drug volume of distribution, vasopressor use, male sex and hypoalbuminemia are…
- Trial name
- PK-VANCO-ICU (NCT02844192)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Hip Strain
Hip Manipulation in Young Adults With Groin, Lateral Hip or Buttock Pain
The purpose of the study is to identify the characteristics of young adults with pain in the groin, lateral hip or buttock who will benefit from manipulation of the hip.
- Trial name
- NCT02842801
- Testing
- Hip manipulation
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Texas Woman's University
Joint Instability, Chronic Disease
Jumping Exercises Approach in Individuals With Chronic Ankle Instability
The aim of this pilot study is to analyze the effect of a 12-week specific jump training compared with conventional therapy in patients with chronic functional instability of the ankle.
- Conditions
- Joint Instability, Chronic Disease, Sprains
- Trial name
- NCT02115971
- Testing
- Jumping exercise, Strength exercise
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Swanenburg
Heart Failure
Myocardial Performance at Rest and During Exercise in Heart Failure With Preserved Ejection Fraction
This study is being done to study how well the heart contracts and relaxes during exercise. In addition to traditional measures of heart function, we will use a new computer program that may improve understanding of why people…
- Trial name
- X-HF-SPECKLE (NCT01747785)
- Testing
- Cardiac rehabilitation, Myocardial deformation imaging, Cardiopulmonary exercise test
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pulmonary Embolism, Right Heart Strain
Study of Diagnosis and Pathophysiology of Pulmonary Embolism (APE 1 Trial)
The purpose of this study is to investigate which method and criterion for diagnosing pulmonary embolism is the best and determine the relationship between blood vessel constriction and clot size in patients developing heart…
- Trial name
- NCT00302601
- Testing
- Scintigraphic interpretation
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Odense University Hospital
Quality of Life
Effectiveness of Nursing Intervention on Caregivers
The purpose of this study is to evaluate the effectiveness of a structured nursing intervention (PCE), including two types of intervention defined in the literature (coping strategies promoting social support and empowerment…
- Trial name
- CuidaCare (NCT01478295)
- Testing
- CuidaCare Intervention, Control Group/Usual Care:
- Where
- Spain
- Volunteers
- 266 people
- Sponsor
- Gerencia de Atención Primaria, Madrid
Atrial Fibrillation
Atrial Fibrillation Prediction Trial.
Atrial Fibrillation (AF) is a common arrhythmia with a prevalence of 1.5-2%. This prevalence increases significantly after 80 years of age.
- Trial name
- AFPRET (NCT02307032)
- Where
- 4 sites in Greece
- Volunteers
- 500 people
- Sponsor
- University of Athens
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery
One technique for the nerve block involves injecting the numbing medicine where the nerve is together (higher up in the back of the thigh).
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot
- Trial name
- NCT01550094
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Percutaneous Coronary Intervention, Myocardial Ischemia
Analysis of Myocardial Layer Specific Systolic and Diastolic Function During and After PCI
Investigators will analyzed systolic and diastolic function during and after ischemia induced by percutaneous coronary intervention.Also will be analyzed a local work index during acute ischemia induced by percutaneous coronary…
- Conditions
- Percutaneous Coronary Intervention, Myocardial Ischemia, Anginal Pain
- Trial name
- PCI-Strain (NCT02004483)
- Testing
- Percutaneous Coronary Intervention
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- RWTH Aachen University
Myopia,, Hyperopia,
Refraction Determination Analysis
Correlating the accuracy of a refraction done over telemedicine to that of a standard refraction, with a study hypothesis that the results will be equivalent.
- Conditions
- Myopia,, Hyperopia,, Astigmatism,, Presbyopia,
- Trial name
- NCT01995435
- Testing
- Telemedicine refraction, Traditional refraction
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lee, Steven, M.D.
Abdominal Pain, Children
Resistance of Helicobacter Pylori to Antibiotics in Children
Helicobacter Pylori (HP) is one of the most common pathogens in humans. This infection can present in children with abdominal pain, vomiting and iron deficiency.
- Conditions
- Abdominal Pain, Children, Bacterial Infection Due to Helicobacter Pylori (H. Pylori), Antibiotic Resistant Strain
- Trial name
- NCT01902589
- Testing
- Helicobacter Pylori Culture
- Where
- Israel
- Volunteers
- 115 people
- Sponsor
- HaEmek Medical Center, Israel
Sprains and Strains
Ankle Manual Therapy for Ankle Sprains
The purpose of this study is to determine the effect of using ankle manual therapy procedures on clinical outcomes in individuals with post-acute ankle sprains.
- Trial name
- AMT (NCT00888498)
- Testing
- Passive Positioning, High-Velocity, Low-Amplitude Stretch, Slow, Mobilization Stretch
- Where
- United States
- Volunteers
- 189 people
- Sponsor
- University of the Pacific
Ankle Sprain
HKT-500 in Adult Patients With Ankle Sprain
The objective of this study is to demonstrate the multiple-dose efficacy and safety of HKT-500 for the treatment of ankle sprain.
- Trial name
- NCT00680784
- Testing
- HKT-500 Ketoprofen Topical Patch
- Where
- 30 sites in United States
- Volunteers
- 260 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Fractures, Sprain
Epidemiology of Incidents and Accidents in Sport. Influence of Moisture.
sports accidents and incidents are relatively frequent. We hypothesize that the pursuit of good hydration, including days without training or competition could prevent their occurrence
- Conditions
- Fractures, Sprain, Stress Fractures, Aches
- Trial name
- NCT02346786
- Testing
- eau minérale d'Aix-Les-Bains, tap water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche Rhumatologique et Thermal