Clinical trials: Strain
Heart Failure With Preserved Ejection Fraction, Diastolic Dysfunction
Sex Related Differences in Cardiac Function
The aim of the study is to investigate sex-specific differences in LV and RV function (systolic and diastolic) with regarding the development and progression of heart failure with preserved ejection fraction based on a…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Diastolic Dysfunction, Systolic Dysfunction
- Trial name
- NCT05796050
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Sepsis, Septic Shock
Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis
Cardiogenic shock is a condition of low cardiac output that represents the end of a progressive deterioration of cardiac function.
- Conditions
- Sepsis, Septic Shock, Cardiogenic Shock
- Trial name
- GLASSES-1 (NCT04141410)
- Testing
- Levosimendan, Echocardiography
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Azienda USL Toscana Centro
Stress, Psychological, Behavioral Symptoms
The Impact of 8 Weeks of a Digital Meditation Application on Work Stress
The aim of this study is to test the effects of a digital meditation intervention in a sample UCSF employees who report mild to moderate stress.
- Trial name
- NCT03527303
- Testing
- Meditation
- Where
- United States
- Volunteers
- 1,458 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Postpartum Depression
Effect of Consuming a Combination of Probiotic Strains on Postpartum Depression
The objective of this trial is to evaluate the effect of consuming a combination of Lactobacillus during the pregnancy and lactation period on the incidence of postpartum depression.
- Trial name
- NCT06651424
- Testing
- Combination of Lactobacillus probiotics (no comercial)
- Where
- 3 sites in Spain
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Adhesive Capsulitis
Spencer's Muscle Energy Technique Along With Strain Counter Strain in Adhesive Capsulitis.
Numerous Physiotherapy techniques have been found to be beneficial but there is no consensus on the best treatment approach for speeding up rehabilitation process and rejuvenating functional capacity in patients suffering from…
- Trial name
- NCT04822324
- Testing
- Spencer Muscle energy technique with conventional Physiotherapy, Strain counter strain along with conventional Physiotherapy and Spencer Muscle energy technique
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cardiopulmonary Bypass, Coronary Artery Bypass
GLS in Difficult CPB Weaning
The goal of this observational study is to learn whether global longitudinal strain (GLS), measured by echocardiography, can predict difficulty separating from cardiopulmonary bypass (CPB) in adults undergoing elective cardiac…
- Conditions
- Cardiopulmonary Bypass, Coronary Artery Bypass, Heart Valve Diseases, Echocardiography
- Trial name
- NCT07390903
- Testing
- Myocardial strain imaging
- Where
- 2 sites in Italy, Turkey (Türkiye)
- Volunteers
- 213 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Healthy Eating Index, Muscle Strain
Evaluation of the Relationship Between Healthy Eating and Intrinsic Capacity in Elderly Individuals
The aim of this study is to evaluate the relationship between intrinsic capacity and healthy eating in elderly individuals.
- Conditions
- Healthy Eating Index, Muscle Strain, Frailty
- Trial name
- NCT05335343
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Burnout, Caregiver
Impact of the Change in Hospital Service of Caregivers During COVID-19 Health Crisis on Operational Strain
The French Armed Forces Health Service caregivers are confronted with specific operational constraints that require physiological adaptation on a daily basis.
- Trial name
- CovIdeDocS (NCT04667962)
- Testing
- Online questionnaire
- Where
- 2 sites in France
- Volunteers
- 307 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Overweight, Obesity
The Effect of PD01 on Cardiovascular Health and Microbial Environment
This randomized, placebo-controlled trial aims to determine the effects of daily administration of a carotenoid-producing Bacillus strain PD01 over a 6-week period on cardiovascular health biomarkers, microbiota composition and…
- Trial name
- NCT02622425
- Testing
- PD01
- Where
- Netherlands
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Brain Injuries, Caregiver Burden
Evaluating the Care Burden of Caregivers of Patients With Brain Injury and Determining the Influencing Factors
Acquired brain injury is a general term including trauma due to head injury or postsurgical damage, vascular accident such as stroke or subarachnoid hemorrhage, toxic or metabolic cause such as hypoglycemia, cerebral anoxia, and…
- Trial name
- NCT04936360
- Testing
- questionnaires for clinical assessments
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Exercise, Heat Strain
Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults
Life in space is completely void of physical and environmental stress. It is well known that living things need regular physical stress (e.g. exercise) to remain strong, functional and healthy.
- Conditions
- Exercise, Heat Strain, Control Condition
- Trial name
- NCT06872762
- Testing
- Exercise, Heat strain
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Muscle; Injury, Quadriceps (Thigh), Tendon Strain
Mechanisms of Tissue Repair After Muscle Injury and Tendon Strain
The study is a 5-week human study including 24 18-35 year old healthy men. Each participant will have muscle injury and tendon strain induced in one leg using neuromuscular electrical stimulation in conjunction with forced…
- Trial name
- NCT05809947
- Testing
- Neuromuscular electrical stimulation
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Monkeypox
A Study Evaluating the Safety and Immunogenicity of MVA Strain Monkeypox Attenuated Live Vaccine
This is a randomized, double blinded, controlled phase I clinical study. To evaluate the safety and immunogenicity of receiving two doses of MVA strain monkeypox attenuated live vaccine in individuals aged 18 years and above.
- Trial name
- NCT06771479
- Testing
- MVA strain monkeypox attenuated live vaccine (low dose), MVA strain monkeypox attenuated live vaccine (high dose)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute Of Biological Products
Heat Stress, Physiological Stress
Efficacy of Electric Fans in Children During Heat Waves
Extreme heat exposure is an escalating global public health concern, with climate change driving increases in the frequency, duration, and intensity of heat events.
- Conditions
- Heat Stress, Physiological Stress, Child Development
- Trial name
- NCT07864103
- Testing
- Simulated exposure to indoor overheating without fans, Simulated exposure to indoor overheating with fans
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Polio, Diphteria, Tetanus and Pertussis
Study of Concomitant Administration of the sIPV and DTaP or MMR
This study is a randomized, open-labeled phase IV clinical trial to evaluate the immunogenicity and safety of concomitant administration of sIPV and DTaP or MMR in infants aged 2 months.
- Conditions
- Polio, Diphteria, Tetanus and Pertussis, MMR Vaccine
- Trial name
- NCT06920069
- Testing
- sIPV, DTaP, bOPV 1,3
- Where
- 9 sites in China
- Volunteers
- 2,640 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Elevated Caregiver Strain, Dementia Caregiver
Leveraging Interventions for Caregiver Growth, Health, Training, Empowerment and Navigation: Comparing Group Behavioral Interventions to Improve Dementia Caregiver Strain
The goal of this clinical trial is to compare two group-based interventions for caregivers of persons with memory loss (N=450) delivered via telehealth.
- Conditions
- Elevated Caregiver Strain, Dementia Caregiver, Caregiver Stress
- Trial name
- LIGHTEN (NCT07868588)
- Testing
- Caring Together, Savvy Caregiver
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- Massachusetts General Hospital
Mechanical Low Back Pain, Chronic Low Back Pain (CLBP)
Iliopsoas Counterstrain and Mechanical Chronic Low Back Pain
The aim of this study is to determine the effects of the Strain-Counterstrain (SCS) technique on alleviating sudden and mechanical chronic low back pain and resolving limited lumbar flexion and extension in individuals with…
- Trial name
- NCT06748859
- Testing
- Counterstrain technique, Exercise therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Marmara University
Healthy
Evaluation of the Acceptability of a Multi-strain Probiotic Supplement (Smile Probio 45B) in Healthy Adults
The goal of this clinical trial is to examine the compliance and acceptability of the probiotic Smile Probio 45B in healthy adults, as well as its effect on gastrointestinal symptoms, fatigue levels, and quality of life.
- Trial name
- NCT07362251
- Testing
- Probiotic
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Anxiety, Digital Eye Strain
Reducing Eye Strain and Anxiety Using a Digital Intervention During Online Learning Class Recess Among Children at Home: A Randomized Controlled Trial
The primary aim of the current study is to conduct a cluster-randomized control trial to evaluate the effectiveness of a novel digital intervention in reducing anxiety and digital eye strain compared to usual care among Chinese…
- Trial name
- RESILIENT (NCT04309097)
- Testing
- Digital intervention, Information-only intervention
- Where
- China
- Volunteers
- 954 people
- Sponsor
- Sun Yat-sen University
Hypertrophic Cardiomyopathy
Study of Hypertrophic Cardiomyopathy Under Stress Conditions. Concordance Between Two Complementary Tests: Stress MRI and Exercice Stress Echocardiography
Hypertrophic cardiomyopathy (HCM) is a primitive myocardic disease and the first of genetic cardiac diseases. The definition of HCM is an increase of the myocardial thickness of the left ventricle (LV) wall without any other…
- Trial name
- CMHStress (NCT02500420)
- Testing
- Diagnosis examens
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Montpellier