Clinical trials: Strain
Inflammation, Gastrointestinal Symptoms
Evaluating the Ability of a Multi-Strain Postbiotic to Impact Inflammation, Immune Components, Gastrointestinal Symptoms, Recovery, Anxiety, and Intestinal Permeability
This study will evaluate the effects of a multi-strain postbiotic supplement on markers of inflammation, immune function, gastrointestinal symptoms, psychological well-being, and intestinal permeability in healthy adults.
- Trial name
- BIO (NCT07387991)
- Testing
- Multi-Strain Postbiotic
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Chagas Disease
Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas Disease
One of the most challenging issues of chronic Chagas disease is to provide earlier detection of heart involvement. Two-dimensional speckle tracking (2-D ST) echocardiography, a new imaging modality with useful applications in…
- Trial name
- NCT02327052
- Testing
- No intervention was performed.
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Sao Rafael
Diarrhea
Low-dose Challenge Model With Enterotoxigenic E Coli
This study will validate a model for testing new vaccines designed to protect against intestinal infections with enterotoxigenic Escherichia coli (ETEC).
- Trial name
- NCT00844493
- Testing
- E coli strain H10407 and buffer, E coli H10407 and buffer
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Groin Strain
Effects of Active Tissue Release Techniques on Groin Pain in 2nd Trimester of Pregnancy
The study will focus on the effects of active tissue release techniques on groin pain, hip range of motion, and functional disability in 2nd trimester of pregnancy.
- Trial name
- NCT06340126
- Testing
- Active release techniques, Relaxation exercises
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy Eating Index, Muscle Strain
Evaluation of the Relationship Between Healthy Eating and Intrinsic Capacity in Elderly Individuals
The aim of this study is to evaluate the relationship between intrinsic capacity and healthy eating in elderly individuals.
- Conditions
- Healthy Eating Index, Muscle Strain, Frailty
- Trial name
- NCT05335343
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Echocardiography, Pregnancy Related Conditions, Unspecified, First Trimester
Echocardiographic Assessment of Ventricular Strain During a Healthy Pregnancy in the First, Second, and Third Trimester.
Pregnancy is a physiological situation that produces transient preload and afterload changes. The heart is subjected to reversible morphological remodelings and hemodynamic and functional adaptations.
- Conditions
- Echocardiography, Pregnancy Related Conditions, Unspecified, First Trimester, Pregnancy Related Conditions, Unspecified, Second Trimester, Pregnancy Related Conditions, Unspecified, Third Trimester
- Trial name
- VStrain123P (NCT04395014)
- Testing
- 2D Echocardiography
- Where
- Mexico
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Miguel Ayala León
Stress, Psychological
Stress Free UCR: The Impact of 8 Weeks of Headspace on Stress in a Heterogeneous University Employee Cohort
The aim of this study is to test the effects of a digital meditation intervention in a sample of high stress UCR employees. We will randomize UCR employees to 8-weeks of either a digital mindfulness intervention (using the…
- Trial name
- NCT03695627
- Testing
- Meditation
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of California, Riverside
Hypertension
The Double Exposure Study: The Impact of Job Strain and Marital Cohesion on Blood Pressure
Psychosocial and lifestyle stressors, such as job strain (JS) and marital factors have previously been associated with a sustained increase in blood pressure (BP).
- Trial name
- NCT00133653
- Testing
- Observational
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
SARS-CoV-2
Safety and Immune Response of Adjuvanted SARS-CoV-2 (COVID-19) Beta Variant RBD Recombinant Protein (DoCo-Pro-RBD-1 + MF59®) and mRNA (MIPSCo-mRNA-RBD-1) Vaccines in Healthy Adults
This is a study of two experimental SARS-CoV-2 vaccines against the virus called SARS-CoV-2 virus. The first of the experimental vaccines is called DoCo-Pro-RBD-1 + M59® and contains a laboratory made protein which looks the same…
- Trial name
- NCT05272605
- Testing
- Adjuvanted SARS-CoV-2 beta variant RBD recombinant protein vaccine (DoCo-Pro-RBD-1 + MF59), SARS-CoV-2 beta variant RBD mRNA vaccine, Normal Saline
- Where
- 2 sites in Australia
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Cystitis, Urinary Tract Infections
Incidence of Cystitis in Women Consuming a Mixture of Cranberry, Cinnamon, Probiotics
Cranberries are traditionally used for urinary comfort and prevention of urinary disorders of bacterial origin and despite an EFSA opinion invalidating the clinical efficacy of cranberries, its mechanism of action has been…
- Trial name
- NCT04987164
- Testing
- Feminabiane CBU
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- CEN Biotech
Heart Failure, Diastolic, Echocardiography
Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking Echocardiography
The goal of this single-center, prospective, observational study is to validate a software package based on an artificial intelligence algorithm for automated non-invasive estimation of LVFP against invasively measured ones by…
- Trial name
- LVEDP (NCT05768698)
- Testing
- Software algorithm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
Atrial Fibrillation, Myocardial Infarction, Acute
Prognostic Role of LA Strain in Acute Myocardial Infarction
This is a single-center retrospective observational study in which we consecutively selected patients diagnosed with acute myocardial infarction from September 2019 to March 2024 at the Affiliated Hospital of Xuzhou Medical…
- Conditions
- Atrial Fibrillation, Myocardial Infarction, Acute, Stroke Ischemic, Mortality
- Trial name
- CMR-MI (NCT06408636)
- Testing
- Cardiac MRI
- Where
- China
- Volunteers
- 780 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Urinary Incontinence, Urinary Incontinence, Stress
Elastographic Assessment of Suburethral Tissue in Continent and Incontinent Women
Strain elastography (SE) will be utilized as a non-invasive imaging technique to evaluate tissue elasticity and biomechanical properties in women with stress urinary incontinence (SUI) and in continent controls.
- Conditions
- Urinary Incontinence, Urinary Incontinence, Stress, Urinary Incontinence (UI), Urinary Bladder, Overactive
- Trial name
- SE-inc1 (NCT06933407)
- Testing
- Strain Elastography
- Where
- Hungary
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Szeged University
Health Care Workers
SEEK Study - Study on Emergency Health Care Workers' Job Strain Evaluated by Karasek Questionnaire
Emergency health care workers are exposed to job strain - defined by Karasek as a combination of high job demands and low job control.
- Trial name
- SEEK (NCT02401607)
- Testing
- Karasek questionnaire and Saliva prelevement
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Cultural Adaptation, Reliability
Turkish Version of Digital Eye Strain Questionnaire (DESQ)
The aims of this study were to perform cultural adaptation of the DESQ and provide information regarding the factor structure, reliability and validity of the instrument in Turkish speaking adults.
- Conditions
- Cultural Adaptation, Reliability, Validity, Adults
- Trial name
- NCT06054542
- Testing
- Cultural adaptation, reliability and validity
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University
H. Pylori Eradication Failure
Mixed Strain H. Pylori Infection in Patients Who Have Problems With Eradication of H. Pylori
The purpose of this study is to determine whether mixed H. pylori strain infection is the reason for eradication failure during treatment of H. pylori infection.
- Trial name
- NCT01164969
- Testing
- Antibiotics to which H. pylori can not develope resistance
- Where
- Slovenia
- Volunteers
- 10 people
- Sponsor
- University Medical Centre Ljubljana
Pancreatic Cancer, Secondary Malignant Neoplasm of Lymph Node
Clinical Impact of EUS Elastography Mean Strain Histograms (SH) and Contrast Peak-enhancement in Focal Pancreatic Masses and Lymph Nodes
The study protocol is based on a multi-center semi-quantitative approach of EUS elastography data in combination with contrast-enhanced EUS, consisting of measuring SR and SH for focal pancreatic masses and lymph nodes, as well…
- Conditions
- Pancreatic Cancer, Secondary Malignant Neoplasm of Lymph Node, Benign Neoplasm of Lymph Nodes, Benign Pancreatic Tumors
- Trial name
- ADVEUS (NCT02459041)
- Testing
- Elastography, contrast enhancement
- Where
- Romania
- Volunteers
- 100 people
- Sponsor
- University of Medicine and Pharmacy Craiova
Measles/Rubella
Freeze-dried Live Attenuated Measles/Rubella Combined Vaccine (Schwarz FF-8 Strain/TO-336 Strain) Special Drug Use Surveillance of Vaccinees After the First Vaccination
The purpose of this survey is to assess the safety freeze-dried live attenuated measles and rubella combined vaccine (Schwarz FF-8 strain/TO-336 strain) (freeze-dried live attenuated measles and rubella combined vaccine "Takeda")…
- Trial name
- NCT02151773
- Testing
- Freeze-dried live attenuated measles and rubella combined vaccine (Schwarz FF-8 strain/TO-336 strain)
- Volunteers
- 3,493 people
- Sponsor
- Takeda
Healthy Volunteers
Deriving Cardiac Reference Ranges at 3.0Tesla in Healthy Volunteers
Current MRI society guidelines recommend that reference ranges for specific imaging techniques (T1, T2 mapping, perfusion) are acquired on the MRI scanner that clinical work and research studies are being carried out on.
- Trial name
- DECADENT-HV (NCT05241184)
- Testing
- Multiparametric stress CMR protocol
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Glasgow
Irritable Bowel Syndrome With Diarrhea, Effects of Probiotics
Multi Strain Probiotic Preparation in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders characterized by recurrent abdominal pain associated with defecation or a change in bowel habits without any structural abnormalities.
- Trial name
- NCT04662957
- Testing
- Maltodextrin
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Children's Memorial Health Institute, Poland