Clinical trials: Strain
Shoulder Impingement, Shoulder Pain
Comparison of Pragmatic Posterior Capsular Stretch and Crossbody Stretch on the Shoulder Mobility
Various stretches are used to lengthen the posterior shoulder capsule. No study has reported the comparison of the pragmatic posterior capsular stretch and cross body stertch
- Conditions
- Shoulder Impingement, Shoulder Pain, Adhesive Capsulitis, Rotator Cuff Tears
- Trial name
- NCT04692649
- Testing
- pragmatic posterior capsular stretch, cross body stretch
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Helping Hand Institute of Rehabilitation Sciences
Cardiovascular Disease
Does OCT Imaging Allow us to See Blood Vessel Development in and Around Deposits of Fat and Calcium Inside Blood Vessels
Cardiovascular disease is the leading cause of illness and death in the world. The disease involves narrowing of blood vessels due to deposits of fat which can become coated in calcium.
- Trial name
- NCT03182348
- Testing
- Optical coherence tomography
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Leicester
Neck Pain, Posterior, Trapezius Muscle Strain
Central Pain Modulatory Effects of Dry-Needling in Patients With Non-Specific Neck Pain
An experimental study will be conducted to evaluate the effect of a single dry needling session, compared to a sham needling session, on pain intensity, local and peripheral hyperalgesia, and conditioned pain modulation in…
- Trial name
- NCT04725825
- Testing
- Dry needling
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- University Ghent
Acute Pain
Diclofenac Patch for the Treatment of Acute Pain Due to Mild to Moderate Wrist Sprain, Strain or Contusion
The purpose of the study is to assess the effectiveness of once daily application of a diclofenac sodium topical patch in reducing acute pain due to mild to moderate wrist sprain, strain or contusion when applied to the painful…
- Trial name
- WIND (NCT00869063)
- Testing
- Diclofenac Sodium Patch
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Cerimon Pharmaceuticals
Adductor Strain
The Effect of 6 Week Adductor Exercise Programs on Adductor Muscle Function and Performance
This research project will investigate the effects of two 6-week adductor (hip muscle) exercise programmes on adductor muscle function and performance.
- Trial name
- NCT05733247
- Testing
- Copenhagen adductor exercise, The adduction and abduction partner exercise
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dublin City University
Influenza
A Dose Ranging Study Comparing Different Combinations of Adjuvanted and Non-adjuvanted Influenza Vaccines in Healthy Children 6 to <36 Months of Age
This study will evaluate the safety and immunogenicity of different combinations of influenza vaccine in healthy young children.
- Trial name
- NCT00848887
- Testing
- Adjuvanted and un-adjuvanted influenza vaccines
- Where
- Belgium
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Novartis
Heart Failure With Preserved Ejection Fraction, Beta Blocker
Carvedilol in HF With Preserved EF
Beta-blockers improve clinical outcomes in heart failure and reduced ejection fraction (HFrEF); but not in those with preserved EF.
- Conditions
- Heart Failure With Preserved Ejection Fraction, Beta Blocker, Myocardial Strain
- Trial name
- NCT05553314
- Testing
- Carvedilol
- Where
- 2 sites in South Korea
- Volunteers
- 63 people
- Sponsor
- Seoul National University Bundang Hospital
Neck Pain
Active Release Versus Strain-Counter-strain Technique in Patients With Non-Specific Neck Pain
The study design will be a randomized clinical trial (RCT) aims to compare the effects of Active Release Technique and Strain-Counterstrain on pain, range of motion, cranio-vertebral angle, and disability in patients with…
- Trial name
- NCT07026006
- Testing
- Active Release Technique, Strain-counterstrain
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Muscle Strain
Skeletal Muscle Strain Injuries and the Connective Tissue: Characterization, Recovery and Optimal Treatment
Firstly, the investigators aim to study the biochemical, structural and functional changes associated with acute muscle strain injury in the acute phase and during rehabilitation in vivo.
- Trial name
- NCT02152098
- Testing
- Acute Early onset of rehabilitation, Acute Delayed onset of rehabilitation, Chronic Exercise
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Bispebjerg Hospital
Dry Eye
Bilberry-containing Capsules for Dry Eye Mitigation
This study investigates whether the oral intake of a bilberry capsule product may relieve dry eye symptoms. Participants will be aged between 20 - 65 years of age, with confirmed diagnosis of dry eye status.
- Trial name
- NCT05737108
- Testing
- Bilberry capsule product
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chung Shan Medical University
Plasmodium Falciparum Infection
A Systems Biology Approach to Malaria Immunity
This is a phase I study that will assess the acquisition of immunity to Pf malaria over the course of 5 sequential Controlled Human Malaria Infections (CHMI) over 2-4 years, in 10 healthy adult participants.
- Trial name
- NCT03014258
- Testing
- NF54 P. falciparum malaria challenge
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Chronic Stress-Induced Strain
Efficacy and Safety of Gynostemma Pentaphyllum(Dungkulcha) Extract on Alleviation of Chronic Stress-induced Strain
The investigators performed a 8-week, randomized, double-blind, placebo-controlled human trial to evaluate the efficacy and safety of Gynostemma Pentaphyllum(Dungkulcha) on alleviation of chronic stress-induced strain.
- Trial name
- NCT03277833
- Testing
- Gynostemma Pentaphyllum(Dungkulcha) Extract(400mg/day)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Parkinson Disease, Anxiety
Treating Anxiety in Parkinson's Disease With a Multi-Strain Probiotic
This study evaluates the use of an oral multi-strain probiotic in the treatment of anxiety in individuals with Parkinson's Disease. Participants will be randomized to either 12-week multi-strain probiotic treatment or placebo.
- Trial name
- TAP (NCT03968133)
- Testing
- Probiotic
- Where
- Canada
- Volunteers
- 61 people
- Sponsor
- University of British Columbia
Constipation
Lactobacillus Casei Strain Shirota Fermented Milk for Alleviating Hard Stools in Vietnam
The objective of this study is to provide evidence supporting the efficacy of fermented milk containing Lactobacillus casei strain Shirota in alleviating hard or lumpy stools.
- Trial name
- NCT05982743
- Testing
- Lactobacillus casei strain Shirota fermented milk
- Where
- Vietnam
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Yakult Honsha Co., LTD
Muscle Tightness, Muscle Strain
Changes in the Quadriceps Muscle After Dry Needling Treatment
The present study aims to examine the mechanical changes following dry needling of the quadriceps muscle. To this end, structural and mechanical changes in quadriceps muscle activity will be measured using M-mode ultrasound.
- Trial name
- NCT06396741
- Testing
- The quadriceps muscle will be punctured with ultrasound control
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Daniel Pecos Martín
Dengue
Dengue Controlled Human Infection Model in Dhaka, Bangladesh
The primary objective is to determine, among dengue-naïve adults in an endemic population, the protective efficacy of TetraVax-DV TV005 vaccine against dengue infection induced by a live recombinant attenuated rDEN2∆30-7169…
- Trial name
- NCT05229354
- Testing
- TV005, rDEN2Δ30-7169 attenuated virus strain
- Where
- Bangladesh
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Beth Kirkpatrick
Irritable Bowel Syndrome
SH-DS01 on Fecal Metagenomic Stability
This is a randomized, double blind, Phase 1 study. There will be a 12-week comparison of the safety of DS-01 versus placebo with a secondary outcome measure of the efficacy in a cohort of 100 men or women with IBS with…
- Trial name
- NCT04598295
- Testing
- DS-01
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Beth Israel Deaconess Medical Center
Heart Failure, Atrial Fibrillation
Statins in Reducing Events in the Elderly (STAREE) Heart Sub-study
The STAREE-HEART sub-study will examine the effect of statin treatment over a 3-year period compared with placebo on markers of cardiac ageing (myocardial dysfunction).
- Conditions
- Heart Failure, Atrial Fibrillation, Healthy Ageing, Hypercholesterolemia
- Trial name
- STAREE-HEART (NCT04536870)
- Testing
- Echocardiography, ECG screening
- Where
- 2 sites in Australia
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- Monash University
Sprain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Transdel Pharmaceuticals is investigating a topical cream formulation consisting of 10% ketoprofen for the local treatment of pain associated with mild to moderate acute soft tissue injury in this confirmatory Phase 3 trial.
- Trial name
- NCT01223053
- Testing
- Ketoprofen 10% cream
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Healthy Volunteer
Human Challenge Model Refinement With Enterotoxigenic Escherichia Coli Strain B7A
The purpose of this study is to determine the safe and optimal dose and regimen (fasting duration) for administering the challenge ETEC strain B7A, a CS6 expressing ETEC strain.
- Trial name
- NCT02773446
- Testing
- ETEC strain B7A (O148:H28 CS6+ LT+ST+) (Lot 0481) in Buffer
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health