Clinical trials: Strain
Heart Failure and Reduced Ejection Fraction
Cardiac Left Atrial Evaluation and Response in HFrEF With Sacubitril/Valsartan
Heart failure is an increasingly common condition that can have a significant impact on quality of life and reduce life expectancy. In recent decades, a number of drugs have been developed specifically for this condition.
- Trial name
- CLEAR (NCT07088471)
- Testing
- Sacubtril/Valsartan
- Where
- Ireland
- Volunteers
- 334 people
- Sponsor
- Connolly Hospital Blanchardstown
Coronavirus Infections
Study of Tixagevimab/Cilgavimab and Regdanvimab Efficacy for Treatment of COVID-19
Study hypothesis: the viral neutralizing monoclonal antibodies Tiksagevimab/Cilgavimab and Regdanvimab have high neutralizing activity against SARS-CoV-2 coronavirus, including Omicron strain, and may be effective in treating…
- Trial name
- NCT05982704
- Testing
- tixagevimab/cilgavimab 150+150 mg, tixagevimab/cilgavimab 300+300 mg, regdanvimab
- Where
- Russia
- Volunteers
- 82 people
- Sponsor
- City Clinical Hospital No.52 of Moscow Healthcare Department
Coronary Artery Disease, Anesthesia
Myocardial Strain Analysis in Anaesthetized Coronary Artery Disease Patients During Hyperoxia and Normoxaemia
The purpose of this study is to investigate the impact of supraphysiologic oxygen (hyperoxia) on myocardial function in anaesthetized patients with coronary artery disease.
- Trial name
- Strecho-O₂ (NCT04424433)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 106 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cirrhosis, Chronic Liver Disease
The Role of Strain Elastography in Staging Liver Fibrosis
AIM: To evaluate the role of Strain Elastography in the assessment of liver fibrosis in chronic hepatopathy
- Trial name
- SELF (NCT02184000)
- Where
- 2 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy Craiova
Childhood Cancer
Cardiac 3D MRI in Pediatric Cancer Patients
This is a non-randomized prospective pilot study in a single academic center with historic controls. This study will compare Cardiac Magnetic Resonance Images (MRI) of patients who have undergone childhood cancer treatment that…
- Trial name
- NCT02130934
- Testing
- Cardiac 3D MRI
- Where
- 2 sites in United States
- Sponsor
- Majd Makhoul
Spasm
Development and Evaluation of a Portable Wedge Device for Calf Stretching to Alleviate Strain and Spasms
This research aimed to contribute valuable insights into the potential benefits of incorporating the portable wedge device into preventive or therapeutic interventions for calf-related musculoskeletal issues.
- Trial name
- NCT06441253
- Testing
- Deep Friction massage, Therapeutic exercises
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Superior University
Neck Muscle Issue, Sternocleidomastoid; Contracture
Functional and Morphological Characteristics of Neck Muscles in Acrobatic Skydivers
An observational cohort study, following the Strengthening the Reporting of Observational Studies in Epidemiology(STROBE) guidelines.
- Conditions
- Neck Muscle Issue, Sternocleidomastoid; Contracture, Deltoid Muscle Strain
- Trial name
- NCT04784195
- Testing
- Observation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
ST-Segment Elevation Myocardial Infarction, Multivessel Coronary Artery Disease
The FAVOR V AMI Trial
The FAVOR V AMI study is a prospective, multicenter, blinded, randomized, sham-controlled trial comparing the long-term clinical outcomes of the "Functional and Angiography-derived Strain inTegration (FAST)" technique…
- Conditions
- ST-Segment Elevation Myocardial Infarction, Multivessel Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- NCT05669222
- Testing
- FAST Technique, Angiography
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Pulmonary Hypertension, Thromboembolism, Pulmonary
Perioperative Portal Vein Pulsatility as a Postoperative Prognostic Indicator in Pulmonary Endarterectomy
The investigators aim to evaluate the utility of portal vein pulsatility as a predictor of the composite outcome of persistent organ dysfunction plus death in patients undergoing elective or urgent pulmonary endarterectomy for…
- Conditions
- Pulmonary Hypertension, Thromboembolism, Pulmonary, Perioperative/Postoperative Complications, Venous Hypertension
- Trial name
- PVP-ETO-CPC (NCT03197792)
- Testing
- All patients
- Where
- France
- Volunteers
- 39 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction
Validating the Speckle Tracking Methods on Soft Tissue Strain, Displacement, and Roles in Physical Therapy
This three-year research project aims to test the hypothesis that strain and displacement characteristics of human soft tissues are influenced by (1) habitual physical activity, (2) functional impairment, and (3) training…
- Conditions
- Ulnar Collateral Ligament Sprain, Tibialis Posterior Dysfunction, Anterior Cruciate Ligament Reconstruction Rehabilitation, Ultrasound Evaluation
- Trial name
- NCT07485530
- Testing
- blood flow restriction training, nordic exercise training
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Constipation, Gastrointestinal Discomfort
Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults
The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its…
- Trial name
- NCT07083596
- Testing
- Experimental: Probiotic with LcS, Control
- Where
- Philippines
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Santo Tomas
Subarachnoid Hemorrhage (SAH), Left Ventricular Dysfunction
Detection of Myocardial Dysfunction in Non-severe Subarachnoid Hemorrhage (WFNS 1-2) Using Speckle-tracking Echocardiography (STRAIN)
Subarachnoid hemorrhage (SAH) can cause transient myocardial dysfunction. Recently, it have been reported that myocardial dysfunctions that occur in SAH are associated with poor outcomes.
- Conditions
- Subarachnoid Hemorrhage (SAH), Left Ventricular Dysfunction, Stress Cardiomyopathy
- Trial name
- SAH-STRAIN (NCT03761654)
- Testing
- Global Longitudinal Strain measure
- Where
- France
- Volunteers
- 117 people
- Sponsor
- University Hospital, Bordeaux
Chronic Low Back Pain
Modifiable Work and Movement Solutions Low Back Pain in Seafood Workers
Chronic low back pain has been identified as a major problem for seafood and agricultural workers, and is known to affect worker health and productivity.
- Trial name
- NCT03524378
- Testing
- Ergonomic and movement modifications
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Florida
Dysbiosis, Prophylaxis
Lactobacillus Reuteri DSM 17938 in Gut Microbiota Development in Infant Born by Caesarean Section
The aim of this study is to assess influence of probiotic Lactobacillus reuteri DSM 17938 on formation of gut microbiota in infant born by Caesarean section.
- Trial name
- NCT03675048
- Testing
- BioGaia Protectis drops
- Where
- Russia
- Volunteers
- 97 people
- Sponsor
- BioGaia AB
Trapezius Muscle Strain
To Compare the Efficacy of Instrument Assisted STM vs BT in Alleviating Pain and Tightness of Trapezius Muscle
Trapezius muscle pain and tightness are common musculoskeletal issues that can significantly impair movement and quality of life.
- Trial name
- NCT07037147
- Testing
- instrument assistance soft tissue mobilisation, Bowen technique
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Superior University
Embolic Stroke of Undetermined Source
Embolic Stroke of Undetermined Source, Continuous Electrocardiography and Transthoracic ECHOcardiography in Hospitalized Patients With Ischemic Stroke
Transthoracic echocardiography (TTE) is recommended in patients with ischemic stroke when cardiac etiology is suspected to help plan secondary stroke management.
- Trial name
- ESECHO (NCT04808258)
- Testing
- C3+ Holter Monitor
- Where
- 2 sites in Denmark
- Volunteers
- 500 people
- Sponsor
- Herlev and Gentofte Hospital
Constipation
Efficacy of Lacticaseibacillus Paracasei Strain Shirota on Clinical Manifestation of Functional Constipation in Mexican Adults
Chronic functional constipation is a gastrointestinal disorder with an approximate prevalence of 14% of the Mexican population, which is characterized by difficult or incomplete defecation and/or infrequent bowel movements, with…
- Trial name
- FC (NCT06432608)
- Testing
- fermented milk, Yakult
- Volunteers
- 50 people
- Sponsor
- University of Guadalajara
Abdominal Aortic Aneurysm, Arterial Stiffness
EndoVascular Aneurysm Repair: Heart Remodeling and Aortic Stiffness Study
Abdominal aortic aneurysm (AAA) is associated with a high burden of cardiovascular morbidity and mortality. Although endovascular aneurysm repair (EVAR) has become the preferred treatment for many patients with infrarenal AAA…
- Conditions
- Abdominal Aortic Aneurysm, Arterial Stiffness, Left Ventricle Remodeling
- Trial name
- EVAR-HRAS (NCT07722793)
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Josip Juraj Strossmayer University of Osijek
Cardiotoxicity, Systolic Dysfunction
Aerobic Exercise is Cardio-protective in Hemato-oncological Disease and New-onset Chemotherapy
Oncological diseases are the main cause of death in developed countries and also in Uruguay. Advances in therapeutics have made possible to aspire to cure and in other cases long-term remission with a significant increase in…
- Conditions
- Cardiotoxicity, Systolic Dysfunction, Exercise, Aerobic
- Trial name
- AEROHEMONCO (NCT04476576)
- Testing
- Aerobic exercise (experimental), Flexibility exercise (active comparator)
- Where
- Uruguay
- Volunteers
- 38 people
- Sponsor
- Lucía Florio
Postoperative Complications
Left Ventricular Global Longitudinal Strain and Postoperative Myocardial Injury
To use left ventricular global longitudinal strain as a means of monitoring myocardial exercise function during anaesthesia in patients with coronary artery disease, to explore the association with the occurrence of postoperative…
- Trial name
- NCT05392426
- Testing
- Left Ventricular Global Longitudinal Strain, EF CO SV EDV ESV
- Where
- 2 sites in China
- Volunteers
- 58 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University