Clinical trials: Strain
Body Temperature Changes, Heat Stress
Progressive Heat Exposure and Physiological Strain
Occupational heat-stress guidelines are commonly based on the level of environmental heat exposure and are largely derived from studies conducted under constant environmental conditions.
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT07847437
- Testing
- Constant Heat Exposure, Progressively Increasing Heat Exposure
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Underweight, Paediatrics
Impact of Bi-26 Supplementation on Weight Gain in Underweight Infants
The burden of disease experienced by underweight children is significant, particularly in low- and middle-income countries. Gut dysbiosis, an imbalance in microbial composition, is thought to play a role in nutrient malabsorption…
- Trial name
- NCT05952076
- Testing
- B. infantis Bi-26
- Where
- 5 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Gates Medical Research Institute
Overactive Bladder Syndrome, Multiple Sclerosis
Efficacy of Lower Limb Exercises on Overactive Bladder Symptoms in Patients With Multiple Sclerosis
The aim of the study (OVERACT_V1) is to verify if the isometric contraction of ankle plantarflexor and Hamstring muscles, induces a significant reduction of overactive bladder symptoms in patients with Multiple sclerosis.
- Conditions
- Overactive Bladder Syndrome, Multiple Sclerosis, Muscle Strain
- Trial name
- NCT03322748
- Testing
- Usual physical therapy+ strengthening of lower limbs muscles, Usual physical therapy
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Raffaele
Tularemia
Safety and Immunogenicity Study of a Live Francisella Tularensis Vaccine
This study is designed to determine the safety and immunogenicity of a Live Francisella tularensis Vaccine
- Trial name
- NCT00584844
- Testing
- Live F tularensis Vaccine
- Where
- United States
- Volunteers
- 484 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Ischemic Heart Disease
Correlation Between Left Ventricular Global Strain Measured by Speckle Tracking Echocardiography and Scar Burden Measured by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Heart Disease
To verify whether GLS and LV mechanical dispersion, measured by two-dimensional speckle-tracking echocardiography (2D-STE) correlate with LV scar burden measured by cardiac MRI in patients with ischemic heart disease.
- Trial name
- NCT04970017
- Testing
- Cardiac MRI, Echocardiography
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Assiut University
Erectile Dysfunction, Cardiovascular Diseases
Echocardiography in Men With Erectile Dysfunction
Cardiovascular disease is the leading cause of morbidity and mortality in the world. To curb disease development, there is, therefore, a need to identify more people at increased risk.
- Conditions
- Erectile Dysfunction, Cardiovascular Diseases, Cardiac Disease
- Trial name
- NCT05285280
- Testing
- Echocardiography
- Where
- Denmark
- Volunteers
- 386 people
- Sponsor
- Herlev and Gentofte Hospital
Systolic Function
Strain Analysis as a Right Ventricle Contractility Marker
The analysis of the systolic function (contractility) of the right ventricle (RV) is fundamental and central in many pathologies in intensive care unit. It can guide physicians in choosing therapeutics.
- Trial name
- NCT03090204
- Testing
- ultrasound measurements
- Where
- 2 sites in France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Sacroiliac Strain, Low Back Pain
Correction of Low Back Pain From Sacroiliac Malrotation With a Simple in Home Exercise
60 participants with low back pain will be examined to determine the direction and extent of sacroiliac malrotation. If malrotation exists, they will be randomized to 3 treatment groups: 1 will be taught how to use their thigh to…
- Trial name
- SIbackpain (NCT03888235)
- Testing
- Immediate corrective exercises, Immediate use of pelvic support belt, Delayed treatment
- Where
- Canada
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Dengue
Dengue 3 Human Infection Model (DENV-3)
To evaluate the effectiveness of candidate dengue vaccine formulations, it is prudent to develop an appropriate challenge model.
- Trial name
- NCT04298138
- Testing
- Dengue virus 3 Live Virus Human Challenge (DENV-3-LVHC)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Endometriosis, Bacterial Vaginosis
Effects of a Multi-strain Oral Probiotic on the Vaginal Microbiota Composition in Healthy Women and Women with Endometriosis
Endometriosis is a chronic inflammatory disease affecting approximately 10-15% of reproductive age women, and, in recent years, an association between this pathology and dysbiosis, either involving the gut or the genital…
- Conditions
- Endometriosis, Bacterial Vaginosis, Healthy Volunteer
- Trial name
- NCT06592976
- Testing
- Multi-strain Oral Probiotic (CDS22-formula)
- Where
- Italy
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Measles/Rubella
Freeze-dried Live Attenuated Measles/Rubella Combined Vaccine (Schwarz FF-8 Strain/TO-336 Strain) Specified Drug-use Survey of Vaccinees After the Second Vaccination
The purpose of this survey is to assess the safety of freeze-dried live attenuated measles and rubella combined vaccine (Schwarz FF-8 strain/TO-336 strain) (freeze-dried live attenuated measles and rubella combined vaccine…
- Trial name
- NCT02158364
- Testing
- Freeze-dried live attenuated measles and rubella combined vaccine (Schwarz FF-8 strain/TO-336 strain)
- Where
- Japan
- Volunteers
- 3,331 people
- Sponsor
- Takeda
Overweight (BMI > 25), Obese, Otherwise Healthy Volunteers
L. Acidophilus (Strain TW01) on Gut Health, Body Composition, and Inflammation
This is a pilot research study to investigate the effects of a probiotic supplement (L. acidophilus, strain TW01) on substances found in the stool and bloodstream, gut bacteria composition, body composition, as well as any…
- Trial name
- NCT06912100
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Elasticity Imaging Techniques, Tendinopathy
Discriminative Validity of Strain Elastography of the Supraspinatus Tendon
This study aims at testing the discriminative validity of strain elastography in the normal and abnormal/pathological Supraspinatus tendon due to tendinopathy
- Conditions
- Elasticity Imaging Techniques, Tendinopathy, Rotator Cuff Tendinitis, Musculoskeletal Disease
- Trial name
- NCT03425344
- Testing
- Diagnostic
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karen Brage
Prostate Cancer
Evaluation Ultrasound Elasticity/Tissue Strain-Hardening Imaging for Prostate Cancer Patients Undergoing Radical Prostatectomy
The primary objective is to perform a pilot trial evaluation of a novel prostate ultrasound imaging software utilizing tissue elasticity measurements to identify tumor foci among men who will undergo radical prostatectomy for…
- Trial name
- NCT00824902
- Testing
- Tissue Elastography Imaging
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- M.D. Anderson Cancer Center
High-Intensity Interval Training, Metabolic Syndrome
Effects of High-intensity Interval Training on Myocardial Strain in Metabolic Syndrome Patients
the effects of high-intensity interval training on myocardial function will be studied in a group of patients under medical treatment for the components of metabolic syndrome.
- Conditions
- High-Intensity Interval Training, Metabolic Syndrome, Myocardial Dysfunction
- Trial name
- NCT06262256
- Testing
- High-intensity interval training
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- University of Castilla-La Mancha
Heat Stress, Temperature Change, Body
Identifying the Limits of Survivability in Heat-exposed Older Females
Climate change increases extreme heat events, elevating global heat-illness risk. Females have reduced heat loss capacity (~5%) compared to males, driven by differences in skin blood flow and sweating responses.
- Conditions
- Heat Stress, Temperature Change, Body, Aging, Thermoregulation
- Trial name
- NCT07032493
- Testing
- Humidity-Ramp Protocol, Above-inflection fixed-condition exposure (5%), Below-inflection fixed-condition exposure (5%)
- Where
- 2 sites in Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Muscle Strength, Botulinum Toxins, Type A
Assessment of the Effect of Botulinum Toxin in Extensor Digitorum Brevis Via Strain Gauge and Nerve Conduction Studies
The purpose of this feasibility study is to determine if temporary weakness of a small foot muscle caused by local injection of botulinum toxin into that muscle can be measured with a strain gauge in addition to the previously…
- Trial name
- NCT00822523
- Testing
- Botulinum Toxin, Type A, Saline
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Necrotizing Enterocolitis of Newborn, Sepsis Newborn
Single Vs Multi-strain Probiotics for Preterm Neonates
The goal of this randomized control clinical trial is to determine if probiotics can prevent mortality and morbidity in preterm neonates. It also evaluates effects of probiotics on feeding pattern and growth.
- Conditions
- Necrotizing Enterocolitis of Newborn, Sepsis Newborn, Growth, Feeding Intolerance
- Trial name
- NCT07296718
- Testing
- Dextrose 10%, Lactobacillus Rhamnosus GG, Bifidobacterium BB-12, Lactobacillus paracasei, L casei-431, Streptococcus thermophilus TH-4
- Where
- Pakistan
- Volunteers
- 249 people
- Sponsor
- Madiha, MPhil
Patellar Tendinopathy / Jumpers Knee
Long-Hold Yielding Isometric Exercise for Patellar Tendinopathy in Weightlifting Athletes
The goal of this clinical trial is to evaluate whether a long-hold yielding isometric exercise program improves pain, tendon vascularity, mechanical properties, and functional performance in weightlifting athletes with patellar…
- Trial name
- QuantFlow (NCT07361848)
- Testing
- Long-Hold Yielding Isometric Exercise Program, Usual-Care Training Condition
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Universidad Complutense de Madrid
Myocardial Dysfunction, Liver Transplant; Complications
Strain Analysis for Assessment of Myocardic Dysfunction During Orthotopic Liver Transplantation
Mycocardial systolic function (contractility) is an essential element of cardio-circulatory physiology during major visceral surgery, in particular during liver transplantation during which several factors are likely to be at the…
- Trial name
- STRAIN ETO (NCT05037838)
- Testing
- Longitudinal strain obtained thanks to transesophageal ultrasound data recorded during liver transplantation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon