Clinical trials: Strain
Heart Disease
Cardiac Elastography to Determine Strain and Strain Rates in the Heart
Cardiac elastography is a new technique to analyze strain and strain rates in many organ systems, including the heart. In this study, cardiac elastography derived from the analysis of raw radiofrequency data obtained from a…
- Trial name
- NCT00205387
- Testing
- cardiac elastography and echocardiography
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Valve Heart Disease, Aortic Stenosis
Comparative Imaging Assessment of Valvular Heart Disease
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right…
- Conditions
- Valve Heart Disease, Aortic Stenosis, Aortic Regurgitation
- Trial name
- NCT04126018
- Testing
- MRI with strain measurement, Echocardiography
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Probiotics, Acute Exercise
The Effect of Probiotics on Exercise Performance and Recovery
This project will involve administering a multi-strain probiotic supplement to investigate the capacity to improve exercise performance and/or recovery. This will be done by assessing physiological measures (e.g.
- Trial name
- NCT05588674
- Testing
- Probiotic Supplement
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Tinnitus
Research Project About Psychological Strain, Quality of Life and Emotional Awareness in Patients With Tinnitus
Validation of PRISM (Pictorial Representation of Illness and Self Measure) as a assessment of quality of life and suffering in patients with tinnitus.
- Trial name
- NCT01837368
- Testing
- observational research
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- University of Zurich
Ankle Sprains, Talofibular; Sprain (Strain)
inStability Treated With Ligament RecOnstruction Augmented With iNternal bracinG
This study evaluates the effect of internal bracing in lateral ligament ankle surgery. Half of the patients will receive the standard Brostrom-Gould reconstruction followed by a standard revalidation protocol including 6 weeks of…
- Trial name
- STRONG (NCT03472404)
- Testing
- Internal Brace augmented ankle Ligament reconstruction, Brostrom-Gould ankle Ligament reconstruction
- Where
- 3 sites in Netherlands
- Volunteers
- 42 people
- Sponsor
- Walter van der Weegen
VRE Colonization
Probiotic Efficacy in VRE Eradication
This study will evaluate the efficacy of a probiotic lactobacillus strain in eradicating VRE in non-symptomatic carriers after 4 weeks of treatment. It will also evaluate the long-term efficacy after 8,16 and 24 weeks.
- Trial name
- PROVE (NCT03560700)
- Testing
- lactobacillus probiotic strain
- Where
- Denmark
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Fetal Cardiac Disorder
Fetal Cardiac Function Evaluation With aCMQ-Strain Fetal (STRAIN)
To assess whether the aCQM-Strain ultrasound method allows a good analysis of fetal cardiac function. Establish normality parameters and compare it with fetuses with risk factors of cardiac dysfunction.
- Trial name
- STRAIN (NCT03536000)
- Testing
- Fetal echocardiography using the aCMQ-Strain method
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Travelers' Diarrhea
Dose-Finding Study of CS19 Expressing ETEC Challenge Strains
This will be a strain and dose-finding study in which CS19-ETEC strain WS0115A will be administered at a starting inoculum of 5 x 108 colony forming units (cfu) to 5 subjects as the initial step to establish a human disease…
- Trial name
- NCT00564863
- Testing
- CS19 expressing ETEC strain
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Nitrate, Caffeine
The Effects of Nitrate, Caffeine, and Cold Exposure on Cardiovascular Function.
Dietary inorganic nitrate supplementation may have positive implications on cardiovascular function. The aim of this project is to determine if nitrate supplementation can attenuate the effects that caffeine and cold exposure…
- Conditions
- Nitrate, Caffeine, Cold Exposure
- Trial name
- NCT06602921
- Testing
- TruBeet inorganic beetroot juice, Caffeine, Cold pressor test
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Trigger Point Pain, Myofascial
Effect of Muscle Energy Technique Versus Strain-counterstrain on Upper Trapezius Trigger Points
Aim of the study To determine the comparative effects of muscle energy technique and strain counter strain in upper trapezius trigger point.
- Trial name
- NCT05258201
- Testing
- Strain-counterstrain, Muscle Energy Technique
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases
Cardioprotective Effects of SGLT2 Inhibitors and GLP-1 Receptor Agonists in Korean Patients With Type 2 Diabetes
This observational study will evaluate the cardiovascular effects of sodium-glucose cotransporter-2 inhibitors (SGLT2 inhibitors) and glucagon-like peptide-1 receptor agonists (GLP-1 receptor agonists) in Korean adults with type…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cardiovascular Diseases, Stage B Heart Failure
- Trial name
- NCT07770737
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Dongtan Sacred Heart Hospital
Hypertension, Left Ventricular Hypertrophy
Sacubitril/Valsartan Versus Amlodipine in Hypertension and Left Ventricular Hypertrophy.
1. Study name: Prospective Comparison of Angiotensin receptor neprilysin inhibitor (ARNI) with Amlodipine on ventricular remodeling in hypertension and left ventricular hypertrophy. 2.
- Trial name
- NCT04929600
- Testing
- sacubitril/valsartan, Amlodipine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Strain of Gastrocnemius Muscle (Diagnosis), Diathermy Plate Burn
Energy Transfer Therapy in Treatment of Medial Gastrocnemius
This study develops the effects of Capacitive and Resistive Energy Transfer Therapy (TECAR) on medial gastrocnemius using thermographic cameras, algometry and lunge tests, in a pre-post study with basketball players using a…
- Conditions
- Strain of Gastrocnemius Muscle (Diagnosis), Diathermy Plate Burn, Thermography, Sports Physical Therapy
- Trial name
- NCT04325750
- Testing
- TECAR Therapy
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Urosepsis, Bladder Cancer
Antibiotic Prophylaxis in Transurethral Prostate Resection (TURP) and Transurethral Bladder Tumour Resection (TURB)
To investigate the use of antibiotic prophylaxis in patients undergoing TURP and TURB. The investigators set up a prospective, randomized controlled trial in which (after exclusion of risk factors) patients will be randomized in…
- Conditions
- Urosepsis, Bladder Cancer, Prostate Hyperplasia, Antibiotic Resistant Strain
- Trial name
- Prophylaxis001 (NCT04212403)
- Testing
- Levofloxacin
- Where
- Belgium
- Volunteers
- 1,350 people
- Sponsor
- Jessa Hospital
Aging
The Effects of a High Protein Diet on Microbiota, Gastrointestinal Function and Wellness in Older Women
The purpose of the proposed study is to determine the effects of consuming a high protein diet on fecal microbial communities, gastrointestinal function and symptoms, and general wellness in older adults.
- Trial name
- NCT02445560
- Testing
- Probiotic capsule and Fiber Sachet
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of Florida
Constipation, Signs and Symptoms
Tolerability and Functional Assessment of a Novel Children's Synbiotic
Recent data support the use of specific probiotic strains in a pediatric population. However, given the wide number of commercial products available, and contradictory data in the literature, healthcare providers and consumers…
- Conditions
- Constipation, Signs and Symptoms, Digestive Signs and Symptoms, Infrequent or Difficult Evacuation
- Trial name
- PDS-08™ (NCT04534036)
- Testing
- PDS-08
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Seed Health
Lung Cancer
Endobronchial Ultrasound Elastography: the Utility of Strain Ratio for Lymph Node Staging in Lung Cancer Patients
The aim of this pilot study is to evaluate EBUS elastography strain ratio in assessment of mediastinal lymph nodes in patients with suspicion for lung cancer for the first time.
- Trial name
- NCT02009319
- Where
- Slovenia
- Volunteers
- 33 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Influenza, Seasonal Influenza
Yearly Strain Variation Study, 2009/2010
The purpose of this study is to verify the immunogenicity and tolerance of a trivalent seasonal influenza vaccine with strain composition according to World Heath Organization/European Union (WHO/EU) recommendation for the…
- Trial name
- NCT00943657
- Testing
- Preflucel [Trivalent seasonal influenza vaccine (split virus, Vero cell-derived)]
- Where
- Austria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alachua Government Services, Inc.
Digital Eye Strain (DES)
Lactic Acid Bacteria for Reducing Blue Light-Induced Eye Fatigue
With the widespread use of digital devices and prolonged screen exposure, digital eye strain (DES), also known as computer vision syndrome, has become a global public health concern.
- Trial name
- NCT07737938
- Testing
- BL531_low dose, BL531_high dose, LR1349_low dose
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Synbio Tech Inc.
Influenza Vaccination, Immune Response
Effects of Lactobacillus Coryniformis CECT5711 on Immune Response to Influenza Vaccination in Adults Over 65.
The objective of the present study is to evaluate the capability of the probiotic strain Lactobacillus coryniformis K8 CECT5711 (Lc K8) to enhance the immune response to influenza vaccine in elderly and the effect on respiratory…
- Conditions
- Influenza Vaccination, Immune Response, Probiotics
- Trial name
- NCT03167593
- Testing
- Lactobacillus coryniformis K8 CECT5711
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.