Clinical trials: Strain
Chagas Disease
Assessment of Speckle Tracking Strain Predictive Value for Myocardial Fibrosis in Chagas Disease
One of the most challenging issues of chronic Chagas disease is to provide earlier detection of heart involvement. Two-dimensional speckle tracking (2-D ST) echocardiography, a new imaging modality with useful applications in…
- Trial name
- NCT02327052
- Testing
- No intervention was performed.
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Hospital Sao Rafael
Vocal Cord Strain (Disorder)
The Impact of Hyperbaric Oxygen Therapy on Vocal Performance in Professional Singers
The aim of the current study is to evaluate the Impact of Hyperbaric Oxygen Therapy on Vocal Performance in Professional Singers
- Trial name
- NCT07879040
- Testing
- Device: hyperbaric oxygen therapy
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Overweight, Healthy
The Effects of a Ruminococcus Torques Strain Bacterium in Healthy Adults.
A randomized, placebo controlled crossover study investigating the potential metabolic effects of the naturally occurring gut microbe Ruminococcus torques in healthy, overweight adults.
- Trial name
- NCT05448274
- Testing
- Ruminococcus torques
- Where
- Denmark
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Oluf Pedersen
Muscle Strength, Botulinum Toxins, Type A
Assessment of the Effect of Botulinum Toxin in Extensor Digitorum Brevis Via Strain Gauge and Nerve Conduction Studies
The purpose of this feasibility study is to determine if temporary weakness of a small foot muscle caused by local injection of botulinum toxin into that muscle can be measured with a strain gauge in addition to the previously…
- Trial name
- NCT00822523
- Testing
- Botulinum Toxin, Type A, Saline
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Influenza Disease
Safety and Immunogenicity of Surface Antigen, Inactivated, Influenza Vaccine Using the Strain Composition 2009/2010 Recommended in Northern Hemisphere in Non-elderly Adult and in Elderly Subjects
Annual trial for registration influenza vaccine with the strain composition for season 2009/2010.
- Trial name
- NCT00918268
- Testing
- Influenza vaccine
- Where
- 3 sites in Italy
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Exogenous Ketosis, Endurance Cycling Performance
The Effects of Exogenous Ketosis on Ultra-endurance Recovery and Performance
The study aims to investigate the effects of post-exercise and pre-sleep ketosis via oral ketone ester supplementation on physical and mental recovery during a multi-day cycling stage race.
- Conditions
- Exogenous Ketosis, Endurance Cycling Performance, Fatigue; Muscle, Heart, Fatigue, Mental
- Trial name
- NCT06965491
- Testing
- Ketone ester supplement
- Where
- Belgium
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Adductor Strain
Impact of Tailored Preventive Exercise Program for Reducing Risk of Hip Adductors Injury
this study will be conducted : To investigate the impact of tailored preventive exercise program in reducing hip adductor loss of isometric strength in professional football players.
- Trial name
- NCT06694220
- Testing
- Tailored preventive exercises, Traditional exercises
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bacterial Vaginosis
Vaginal lIve Biotherapeutic RANdomized Trial
The goal of this randomized clinical trial is to evaluate safety and biologic effect of a multi-strain vaginal L. crispatus live biotherapeutic product (LBP) in people receiving antibiotic treatment for bacterial vaginosis (BV).
- Trial name
- VIBRANT (NCT06135974)
- Testing
- LC106, LC115, Metronidazole Oral
- Where
- 2 sites in United States, South Africa
- Volunteers
- 24 people
- Sponsor
- Massachusetts General Hospital
Acute Otitis Media
Effect of a New Probiotic Strain on Recurrent Acute Otitis Media in Children (PROMAR)
An interventional, randomized, double-blind, placebo-controlled study will be conducted to investigate the effect of a new probiotic strain Lactobacillus salivarius PS7 on Acute Otitis Media (AOM) in children with recurrent AOM…
- Trial name
- PROMAR (NCT03614117)
- Testing
- Lactobacillus salivarius PS7 during 6 months, Lactobacillus salivarius PS7 during 3 months
- Where
- Spain
- Volunteers
- 222 people
- Sponsor
- ProbiSearch SL
Poliomyelitis
A Study on Immunity Duration Against Polio Over 18 Months Infants After 2 or 3 Primary Doses Sabin IPV in China
In 2017, China CDC conducted a study titled "A Study of Immunogenicity and Seroconversion With Sabin IPV Schedules in China". At present, all the infants in the monitoring cohort were over 18 months old and at least one year had…
- Trial name
- NCT04614597
- Testing
- Sabin strain inactivated polio vaccine
- Where
- China
- Volunteers
- 774 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Injuries, Genetic Change
Candidate Gene Association Study With Injury in Elite Male Youth Football Players
Understanding how candidate genes, previously associated with injury susceptibility, influence the incidence of muscle, bone, ligament, and tendon injuries across the development pathway of elite footballers may provide valuable…
- Trial name
- NCT04952662
- Testing
- Genetic variants
- Where
- 2 sites in United Kingdom
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Plantar Fascitis
Active Release Technique Versus Strain-Counter Strain in Improving Pain and Function in Plantar Fasciitis
This randomized controlled trial compares the effectiveness of Active Release Technique (ART) and Strain-Counterstrain (SCS) in treating plantar fasciitis.
- Trial name
- NCT07078513
- Testing
- Active release Technique, Strain counter strain tecnhnique
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Healthy
Dose-Finding Study of Lyophilized Shigella Sonnei 53G Challenge Strain
Development of an S. sonnei human challenge model using a newly manufactured lyophilized lot of S. sonnei strain 53G (Lot 1794) that can be used in the future as a challenge strain for all S. sonnei vaccine candidates.
- Trial name
- NCT02816346
- Testing
- Shigella sonnei 53G
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- PATH
Surgery
Global Longitudinal Peak Systolic Strain (GLPSS) Derived From Transesophageal Echocardiography - A Reliable Measure of Systolic Function?
Systolic function is a substantial determinant of overall hemodynamics and organ function. Therefore assessment of left ventricular systolic function (LVF) has been of central interest in Echocardiography.
- Trial name
- 2DSonTOEcho (NCT00877565)
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Cervicogenic Headache
Comparative Effects of Strain-counterstrain and Muscle Energy Techniques on Neck Pain and Functional Disability in Patients with Cervicogenic Headache
The primary objective of this study is to compare effects of SCS and METs on reduction of neck pain intensity and improvement in functional disability in individuals with CGH.
- Trial name
- SCS METs (NCT06811766)
- Testing
- Strain-counterstrain, Muscle energy techniques
- Volunteers
- 54 people
- Sponsor
- University of Faisalabad
High-dose Steroids, Myocardial Function, Longitudinal Strain
The Effect of High Dose Glucocorticoid Steroids on Myocardial Function
Long term steroid exposure, as in Cushing's disease, causes myocardial dysfunction, hypertrophy and fibrosis in addition to causing obesity, hypertension and glucose intolerance.
- Trial name
- NCT04649294
- Where
- Israel
- Volunteers
- 23 people
- Sponsor
- Hillel Yaffe Medical Center
Preventive Avian Flu
Phase I Safety and Immunogenicity of Live Attenuated Influenza H5 Candidate Vaccine Strain A/17/Turkey/Turkey/05/133 (H5N2) in Healthy Thai Volunteers
The purpose of this study is to evaluate safety and reactogenicity of live attenuated influenza H5 vaccine candidate strain A/17/turkey/Turkey/05/133 (H5N2) manufactured by GPO, in Thailand to previously healthy Thais.
- Trial name
- NCT01656356
- Testing
- Avian Flu Vaccine
- Where
- Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mahidol University
Dengue
Expansion of a Dengue-1 Live Virus Human Challenge
To evaluate the effectiveness of candidate dengue vaccine formulations, it is prudent to develop an appropriate challenge model.
- Trial name
- NCT03869060
- Testing
- Dengue-1 Virus-Live Virus Human Challenge (DENV-1-LVHC)
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Seasonal Influenza, Vaccine
Safety and Immunogenicity of Trivalent Split Influenza Vaccine Using the Strain Composition 2007/2008
Annual trial for registration of trivalent split influenza vaccine with the strain composition of the season 2007/2008 in healthy adult and elderly subjects
- Trial name
- NCT00498303
- Testing
- trivalent split influenza vaccine
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Novartis
Solid Tumor, Immune Checkpoint Inhibitor
Safety and Efficacy of RX-af01 Combined With PD-1 Antibody
This phase I trial evaluates the effects of RX-af01 in combination with toripalimab (PD-1 antibody), in treating patients with refractory advanced solid tumors, including melanoma, nasopharyngeal squamous carcinoma, esophageal…
- Conditions
- Solid Tumor, Immune Checkpoint Inhibitor, Intestinal Flora
- Trial name
- NCT05576961
- Testing
- RX-af01, Mixed bacteria, High dose RX-af01
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University