Clinical trials: Strain
Valve Heart Disease, Aortic Stenosis
Comparative Imaging Assessment of Valvular Heart Disease
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right…
- Conditions
- Valve Heart Disease, Aortic Stenosis, Aortic Regurgitation
- Trial name
- NCT04126018
- Testing
- MRI with strain measurement, Echocardiography
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The Cleveland Clinic
Hypertrophic Cardiomyopathy (HCM)
LA-HCM Study : Rivaroxaban for Antithrombotic Prevention in Hypertrophic Cardiomyopathy Patients With Abnormal Left Atrial Strain.
Hypertrophic cardiomyopathy (HCM) is a common (> 1/500 in the general adult population) genetically transmitted disease impacting markedly patients' lives from the early ages to the latest.
- Trial name
- LA-HCM (NCT07202897)
- Testing
- Anticoagulant treatment Rivaroxaban, Best medical therapy
- Where
- 17 sites in France
- Volunteers
- 532 people
- Sponsor
- Rennes University Hospital
Metastatic Colorectal Cancer
MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases
The goal of this study is to investigate the value of MR elastography-based SII as a means of detecting HGP noninvasively in patients with pathology-proven CRLM.
- Trial name
- NCT06208397
- Testing
- Magnetic Resonance Elastography and routine MRI
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Groin Strain
Effects of Active Tissue Release Techniques on Groin Pain in 2nd Trimester of Pregnancy
The study will focus on the effects of active tissue release techniques on groin pain, hip range of motion, and functional disability in 2nd trimester of pregnancy.
- Trial name
- NCT06340126
- Testing
- Active release techniques, Relaxation exercises
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Endometriosis, Bacterial Vaginosis
Effects of a Multi-strain Oral Probiotic on the Vaginal Microbiota Composition in Healthy Women and Women with Endometriosis
Endometriosis is a chronic inflammatory disease affecting approximately 10-15% of reproductive age women, and, in recent years, an association between this pathology and dysbiosis, either involving the gut or the genital…
- Conditions
- Endometriosis, Bacterial Vaginosis, Healthy Volunteer
- Trial name
- NCT06592976
- Testing
- Multi-strain Oral Probiotic (CDS22-formula)
- Where
- Italy
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Musculoskeletal Strain, Ergonomics
Ergonomic Challenges for Surgeons; The Problem and Solutions
Work-related musculoskeletal disorders (WMSDs) are highly prevalent among surgeons. Despite growing awareness, there remains a lack of detailed data on the specific postures that contribute to ergonomic risk, particularly within…
- Conditions
- Musculoskeletal Strain, Ergonomics, Posture
- Trial name
- NCT06938958
- Testing
- Video and Motion Analysis
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Typhoid Fever
CVD 909 Vi Prime Boost Study
The purpose of this research study is to see if giving a typhoid vaccine by mouth (an experimental vaccine, CVD 909) before giving a vaccine shot (Typhim Vi) will result in a better immune response than giving Typhim Vi vaccine…
- Trial name
- NCT00326443
- Testing
- CVD 909, Vi Polysaccharide
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Postural; Strain
The Impact of Intraoperative Stretching Microbreaks on Otolaryngologists
There have been numerous survey-based and observational studies reporting a high percentage of otolaryngologists suffering from work-related musculoskeletal symptoms, in which more than half attributed to poor ergonomics in the…
- Trial name
- NCT04806308
- Testing
- Otolaryngology stretching micro-breaks (OSMB)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- George Washington University
Lower Back Myofascial Pain Syndrome
Effect of Strain Counter Strain Technique in Treatment of Lower Back Myofascial Pain Syndrome
This study aims to investigate the impact of impact of strain counterstrain technique on pain, lumbar range of motion and functional impairment in patients with lower back Myofascial pain syndrome.
- Trial name
- NCT06138860
- Testing
- strain counter strain technique, physical therapy exercises
- Where
- Saudi Arabia
- Volunteers
- 30 people
- Sponsor
- Cairo University
Inflammation
Efficacy of a Probiotic Strain on Level of Markers of Inflammation in an Elderly Population
To investigate the effectiveness of two doses of the probiotic strain Bif-038 on markers of low-grade inflammation in a elderly population
- Trial name
- NCT05529693
- Testing
- Experimental: Bif-038 arm, high dose, Experimental: Bif-038 arm, low dose
- Where
- Ireland
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Occupational Musculoskeletal Disorders, Healthy
Impact in Life Quality of a Educational Program for Prevention of Occupational Musculoskeletal Disorders in Workers
The study consists of evaluating the efficacy of an Educational Program for prevention of occupational musculoskeletal problems in workers.
- Trial name
- NCT00874718
- Testing
- educational program, General education
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Adductor Strain
The Effect of 6 Week Adductor Exercise Programs on Adductor Muscle Function and Performance
This research project will investigate the effects of two 6-week adductor (hip muscle) exercise programmes on adductor muscle function and performance.
- Trial name
- NCT05733247
- Testing
- Copenhagen adductor exercise, The adduction and abduction partner exercise
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dublin City University
Astrocytic Tumors, Glioblastoma Multiforme
Phase I Study of Safety and Immunogenicity of ADU-623
This is a study for patients with brain tumors called astrocytic tumors. The study will enroll patients who have received standard treatment. The study will test a vaccine called ADU-623.
- Conditions
- Astrocytic Tumors, Glioblastoma Multiforme, Anaplastic Astrocytoma, Brain Tumor
- Trial name
- NCT01967758
- Testing
- Cohort 1, Cohort 2, Cohort 3
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Healthy, Carotid Artery Diseases
Early Detection of Vascular Dysfunction Using Biomarkers From Lagrangian Carotid Strain Imaging
The purpose of this research is assess imaging and identification of soft plaque that undergoes large deformations or strain will identify plaque vulnerable to rupture which could lead to 'silent strokes'.
- Trial name
- NCT04632485
- Testing
- Ultrasound imaging, Magnetic Resonance Imaging (MRI), Neurocognitive testing
- Where
- United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison